新浪科技讯 1月7日晚间消息，近日，前脑虎科技CEO彭雷与盛大集团、天桥脑科学研究院创始人陈天 桥联合创立超声波脑机接口公司格式塔（Gestala）成立。据悉，目前该公司已落地成都天府国际生物 城，并入驻上海脑机接口产业聚集区，旨在探索下一代全脑信号读写与分析。 长期以来，全球脑科学研究面临"全脑成像"与"实时响应"难以兼顾的困境：fMRI虽能实现全脑成像，但 血氧信号延迟达3-10秒，无法捕捉神经环路时序关系；侵入式电极虽能达到10微秒级实时响应，却局限 于局部脑区监测。而超声波技术通过采集血流信号间接解码神经活动，在侵入式脑机接口的同等设备体 积下可覆盖25%的全脑体积，既能触及大脑深部区域，又能实现多脑区同步监测，为脑科学研究提供了 全新工具。 据悉，在产品落地方面，格式塔计划分代系推进：第一代台架式设备将聚焦慢性疼痛管理，预计2026年 底启动国家药品监督管理局（NMPA）相关注册流程；第二代将推出可穿戴式设备，持续拓展"治病救 人"的应用场景。目前，公司已与华山医院、协和医院、华西医院等建立合作框架，未来将深化"产学研 医"协同，针对更多适应症展开临床研究。 陈天桥和妻子雒芊芊十年来深耕脑科学领域， ...

小鼠"航天员"启程 西工大太空实验舱成功入轨 同时，太空实验舱搭载了2只雄性小鼠，将在舱内开展小鼠在轨旷场试验、穿梭试验、位置偏爱和位置 厌恶试验以及社交和本能行为观察与测试。本次载荷还携带了自主开发的植入式脑机接口微系统在轨测 试其可靠性。 中新网西安12月17日电 (记者 阿琳娜)记者17日从西北工业大学获悉，13日09时08分45秒，由该校三航 脑科学与脑技术研究中心、生命科学与技术学院、航天学院、柔性电子全国重点实验室(柔性电子研究 院)、无人系统技术研究院联合团队研发的"AI辅助天地孪生太空小鼠无人智能实验舱"(AiTEM)装载2只 雄性小鼠，搭载迪迩五号空间试验飞行器，由快舟十一号遥八运载火箭从酒泉卫星发射中心发射升空， 成功入轨530公里近地球轨道，开展长期空间在轨与地面同步验证。 以上功能舱将为了解哺乳动物大脑在空间失重环境下的神经可塑性，尤其是在重力信号缺失情况下了解 大脑如何整合感觉调节身体位置与姿态，如何在资源有限情况下保持群体认知与协作等诸多关键科学问 题提供核心数据和技术支撑。 据了解，该太空实验舱专为小鼠在空间失重环境下脑科学研究和行为认知实验研究而设计研制，实现了 小鼠在太空环境 ...

2014年，程和平院士牵头启动国家重大仪器专项"超高时空分辨微型化双光子在体显微成像系统"的研 发，历经10余年完成4次技术迭代：第一代2.2克微型化双光子显微镜，首次实现自由活动小鼠神经突触 清晰稳定的功能成像；第二代系统将视野扩大7.8倍，并具备三维成像能力；第三代系统采用三光子荧 光成像原理，实现自由行为小鼠深脑海马区观测；而最新问世的第四代系统，在多色激发、深脑成像与 多尺度观测3个维度齐头并进，实现了标志性的技术突破。 "过去受空芯光纤功能限制，只能用微型显微镜看单种类型细胞。现在不同类型细胞都可用不同颜色的 荧光蛋白标记，就能清楚看到多种细胞间的复杂行为，研究其如何协同互作。"吴润龙介绍。 微型化双光子显微成像是一种基于双光子吸收和荧光激发的非线性光学成像技术，其关键部件之一是空 芯光纤。团队成功研制出的700—1060纳米超宽带反谐振空芯光纤，一举解决了传统带隙空芯光子晶体 光纤仅支持单色激光的限制，使得多波长飞秒脉冲激光得以低损耗、低色散地传输，为同时观测多种细 胞功能结构奠定了物理基础。 "通过它，阿尔茨海默病模型小鼠的脑部细胞和细胞器动态可清晰呈现。"研究团队成员邱姗介绍，在这 款显微镜的 ...

Core Insights - The research presents the first detailed cross-species mammalian brain cell development atlas, providing unprecedented reference for understanding early brain formation and the origins of neurodevelopmental disorders [1][2][3] - Approximately 15% of children and adolescents are affected by neurodevelopmental disorders, highlighting the urgency of understanding critical periods of brain development [1] Group 1: Research Findings - The study, part of the BRAIN Initiative Cell Atlas Network (BICAN), integrates single-cell genomics, spatial transcriptomics, and advanced imaging techniques to construct a comprehensive brain cell atlas across multiple species [1] - A focus on GABAergic inhibitory neurons in the mouse forebrain revealed their migration process from birthplace to functional locations, which is crucial for motor, memory, and emotional regulation [2] - The research tracked over 770,000 single cells in the mouse visual cortex from embryonic to early adult stages, showing that brain cell diversification continues after birth, particularly during the initial visual experiences [2] Group 2: Implications for Future Research - The use of BARseq technology allowed for the mapping of gene expression profiles of millions of neurons, confirming the critical role of sensory experiences in brain region specialization [3] - The findings provide a solid framework for studying the origins of developmental disorders such as autism and schizophrenia, potentially leading to early diagnosis and targeted interventions [3]

Group 1 - The company, Zhejiang Century Huatong Group Co., Ltd., has been found to have committed violations including false records in annual reports from 2018 to 2022, specifically regarding goodwill and fictitious software copyright transfer business [1] - The company’s executives, including Wang Yifeng and Shao Heng, failed to fulfill their duties to ensure the authenticity and completeness of the annual report information, violating exchange regulations [1] - The Shenzhen Stock Exchange issued warning letters to the involved executives and recorded their actions in the securities and futures market integrity archives [1] Group 2 - ST Huatong was established in 2005 and listed on the Shenzhen Stock Exchange in July 2011, initially starting with automotive parts before transitioning to the internet gaming industry in 2014 [2] - In 2019, the company completed the acquisition of Shengqu Games for 29.8 billion, becoming a leading company in the cultural media sector in A-shares [2] - Currently, the company operates in three main business areas: internet gaming, automotive parts manufacturing, and artificial intelligence cloud data, along with various other fields including brain science research and application development [2] Group 3 - As of the close on May 12, ST Huatong's stock price was 8.01 yuan per share, with a slight increase of 0.12%, and a total market capitalization of approximately 59.7 billion [3]

Group 1: Breakthroughs in Life Sciences - The exhibition at the Zhongguancun Forum showcased significant advancements in life sciences, including high-speed heavy ion bombardment for tumor treatment and the artificial cultivation of neuron cells from stem cells [1] - A self-developed two-photon microscope, weighing only 2.2 grams, allows real-time imaging of brain cells in running mice, contributing to groundbreaking research in autism and neural resilience [2] - The development of a 3D brain organoid culture system enables the simulation of human brain growth and development, which is crucial for understanding diseases like autism [3] Group 2: Medical Equipment Advancements - The domestically developed heavy ion accelerator has been utilized for tumor treatment, significantly reducing treatment costs compared to imported systems [4] - Robotic-assisted surgeries have improved precision and reduced incision sizes, allowing younger doctors to perform complex procedures with greater ease [5] - The integration of internet technology with robotic surgery enables remote operations, bringing quality medical resources closer to the public [5]