Core Viewpoint - The recent round of national drug procurement has resulted in 4,163 products from 1,020 companies being shortlisted, covering 316 commonly used drugs across 26 therapeutic areas, with only 21 original drugs selected, representing less than 10% of the total [1][2]. Group 1: Procurement Details - The procurement aims to reduce drug prices and patient burdens while reallocating saved healthcare funds to innovative drugs [2]. - The procurement process involved 51,000 medical institutions, with a high selection rate of 93% and an average of 14 companies selected per product [2][3]. - The results of this procurement are expected to be implemented by the end of March 2026, with a procurement cycle lasting until the end of 2028 [2]. Group 2: Original Drug Participation - The selected original drugs include various formulations from companies like Bristol-Myers Squibb, Sanofi, and Bayer, with some previously shortlisted in earlier rounds [3]. - Notable original drugs that did not participate in this round include AstraZeneca's gefitinib and Sanofi's clopidogrel, which had previously been selected [4][3]. Group 3: Market Dynamics - The phenomenon known as "patent cliff" has led to significant declines in sales and profits for original drugs post-patent expiration, making it challenging for them to maintain market share without substantial price reductions [6]. - Some original drug companies have reduced or dissolved their sales teams for products affected by procurement policies, yet many still find market opportunities outside public hospital procurement [7]. - Cross-national pharmaceutical companies are increasingly focusing on innovative drug development while divesting mature product lines to local firms [8][9].

2026.02. 12 本文字数：2499，阅读时长大约4分钟 作者 | 第一财经 林志吟 近日，1至8批国家集采药品新一轮接续采购已诞生拟中选结果，共有1020家企业的4163个产品获 得拟中选资格，涉及316种常用药品，覆盖抗感染、抗肿瘤、降血糖、降血压、降血脂、神经系统、 呼吸系统、消化系统等26个治疗领域。 从这接续采购的316种药品来看，据第一财经记者统计，有原研药中标的品种共有21个，整体占比 不到一成。 不到一成的原研药中标 国家药品集采，针对的仿制药以及过了专利保护期的原研药这两大类产品，一方面，挤掉药价虚高的 水分，降低患者用药负担；另外一方面，通过集采节省下的医保资金，转向支付临床价值显著的创新 药，满足临床亟需，鼓励药企研发创新。 本次是针对1-8批国家集采药品新一轮接续采购，由江苏、河南、广东三省医保局联合牵头，各省份 全部参与，实现了采购规则规范统一。企业只需在线投标一次，中选即可实现全国销售。具备投标资 格的企业绝大多数参与投标报价，整体中选率高达93%，每个品种平均14家企业中选。 本次接续采购，国内药品上市许可持有人（含药品注册批件持有人）、境外药品上市许可持有人及其 境内责任 ...

凭借品牌优势在院外市场找到新的发展空间。 近日，1至8批国家集采药品新一轮接续采购已诞生拟中选结果，共有1020家企业的4163个产品获得拟中 选资格，涉及316种常用药品，覆盖抗感染、抗肿瘤、降血糖、降血压、降血脂、神经系统、呼吸系 统、消化系统等26个治疗领域。 2018年以来，随着国家组织的药品集采启动，医药行业逐渐走向分水岭，过了专利保护期的原研药难以 在中国市场维持高利润且垄断局面，而原来以销售这类药物为生的跨国药企这几年已在密集调整业务， 重塑在华发展战略。 一些原研药虽然缺席集采，但并不意味着从市场消失，相反凭借品牌优势仍在院外市场找到新的发展空 间。 不到一成的原研药中标 国家药品集采，针对的仿制药以及过了专利保护期的原研药这两大类产品，一方面，挤掉药价虚高的水 分，降低患者用药负担；另外一方面，通过集采节省下的医保资金，转向支付临床价值显著的创新药， 满足临床亟需，鼓励药企研发创新。 本次是针对1-8批国家集采药品新一轮接续采购，由江苏、河南、广东三省医保局联合牵头，各省份全 部参与，实现了采购规则规范统一。企业只需在线投标一次，中选即可实现全国销售。具备投标资格的 企业绝大多数参与投标报价 ...

Core Insights - Qilu Pharmaceutical Group is establishing a global R&D headquarters in Zhangjiang Science City, with a total investment of approximately 3 billion yuan, focusing on innovative drug development in oncology, autoimmune diseases, metabolism, and neurological disorders [1] - The company has a rich product line with over 300 products covering multiple therapeutic areas, and it has established a strong sales network both domestically and internationally [2][4] - Qilu Pharmaceutical has been recognized as a leading player in the domestic pharmaceutical industry, ranking 3rd in the Ministry of Industry and Information Technology's list of China's top 100 pharmaceutical companies in 2023 [3] Investment and R&D - The company has consistently invested in R&D, with an expected expenditure of over 4.38 billion yuan in 2024, accounting for 12% of its sales revenue, and a cumulative investment of over 20 billion yuan during the 14th Five-Year Plan period [3] - Qilu Pharmaceutical has established a comprehensive innovation management system, focusing on both innovative and generic drugs, with annual R&D spending for generics stable at 1-1.2 billion yuan [3] Global Market Presence - Qilu Pharmaceutical's products have been certified by various international regulatory bodies, enabling its entry into global markets, with 28 of its 100 procurement-winning products sold in 33 countries and regions [2][4] - The company has established four innovation centers in the U.S. and China to enhance its global R&D footprint, with products sold in over 100 countries and regions [5][6] Strategic Location and Collaboration - The choice of Zhangjiang Science City for the new R&D headquarters is strategic, leveraging Shanghai's robust biopharmaceutical ecosystem and innovation environment [10] - The collaboration aims to strengthen resource integration and collaborative innovation, contributing to the development of the biopharmaceutical industry in Shanghai [10][11]

Core Viewpoint - Qilu Pharmaceutical Group is establishing a global R&D headquarters in Zhangjiang Science City, Shanghai, with a total investment of approximately 3 billion yuan, focusing on innovative drug development in areas such as oncology and autoimmune diseases [2][4]. Group 1: Company Overview - Qilu Pharmaceutical is a large modern pharmaceutical enterprise in China, engaged in the research, production, and sales of drugs for various diseases, including oncology and cardiovascular conditions [2][3]. - The company has over 300 products on the market, with a sales network that extends to North America, Europe, Japan, and Australia, establishing partnerships with global firms like Pfizer and Novartis [3][5]. - Qilu has been recognized as the 3rd largest pharmaceutical company in China by the Ministry of Industry and Information Technology in 2023, reflecting its leading position in the domestic pharmaceutical industry [4]. Group 2: R&D Investment and Achievements - The company has committed to a stable annual R&D investment of 4.38 billion yuan in 2024, which constitutes 12% of its sales revenue, with a projected total R&D investment exceeding 20 billion yuan during the 14th Five-Year Plan period [4][5]. - Qilu has developed numerous significant new drugs, including Erlotinib and Bevacizumab, and has received over 100 invention patents, contributing to its strong innovation capabilities [4][5]. - The company has established a comprehensive technology innovation management system, focusing on both innovative and generic drugs, creating a "dual-drive" development model [4]. Group 3: Global Market Expansion - Qilu's products are sold in over 100 countries and regions, with 31 formulations exported to the U.S. and 17 to Europe, demonstrating its competitive position in the global pharmaceutical market [6][8]. - The company has achieved significant market shares in various regions, with 38 products holding the top market position in their respective countries [6][8]. - Qilu has set up four innovation centers in the U.S. to enhance its global R&D layout, forming a complete innovation development system that covers the entire process from early discovery to commercialization [5][8]. Group 4: Strategic Development in Zhangjiang - The new global R&D headquarters in Zhangjiang Science City will cover a total area of approximately 46,000 square meters, with a focus on creating a collaborative innovation environment [7][8]. - This strategic move follows the establishment of the Shanghai R&D center in 2018 and aims to leverage Shanghai's strong biopharmaceutical ecosystem to drive high-quality industry development [8][9]. - The collaboration is expected to enhance resource integration and collaborative innovation, contributing to the development of a new highland for the biopharmaceutical industry in Shanghai [8][9].

Policy Developments - The National Medical Products Administration (NMPA) is seeking public opinions on the revised procedures for conditional approval of drug listings to improve the review and approval system [2] Drug and Device Approvals - Xuno Pharmaceutical's oral cancer drug, Abexinostat, is proposed for priority review by the NMPA, aimed at adult patients with relapsed or refractory follicular lymphoma who have received at least two prior systemic therapies [5] - LuKang Pharmaceutical has received the drug registration certificate for Gefitinib tablets, a first-generation targeted drug for non-small cell lung cancer with EGFR gene mutations [6] Capital Market Activities - Shenzhen Keximingde Medical Technology Co., Ltd. completed a multi-hundred million RMB A+ round financing, with funds allocated for brand building and R&D of soft endoscope products [8] - Buchang Pharmaceutical announced the abandonment of the preferential right to acquire shares in its subsidiary, Shaanxi Modern Innovation, resulting in an 86.50% ownership stake post-transfer [9] - Taiji Group plans to optimize its equity structure by acquiring stakes in its subsidiaries for a nominal price [10] Industry Developments - Chugai Pharmaceutical and Gero PTE have signed a $220 million collaboration agreement to integrate Gero's AI-driven platform into Chugai's R&D strategy for developing therapies for age-related diseases [12] - Kanghua Biotech has terminated its collaboration with Xiran Bochuang on the development of mRNA vaccines for tuberculosis, indicating a strategic shift towards in-house R&D capabilities [13] Shareholder Activities - Guizhou Jin Domain Medical Testing Group announced that major shareholder Guochuang Kaiyuan intends to reduce its stake by up to 1% through market transactions [16] - Haichuang Pharmaceutical reported that shareholder Yingchuang Power has cumulatively reduced its stake by 0.28% [17] - Tongrentang announced the resignation of its executive vice president, Zhang Chunyou, who will continue to serve in a managerial role at a subsidiary [18]

Core Viewpoint - LuKang Pharmaceutical (600789) has received the drug registration certificate for Gefitinib tablets and the approval notice for the raw material drug from the National Medical Products Administration, indicating a significant advancement in its oncology product portfolio [1] Company Summary - Gefitinib is an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) patients with sensitive EGFR gene mutations [1] - The company has invested approximately 11.1491 million yuan in the research and development of Gefitinib tablets and about 9.9 million yuan in the raw material drug [1] Industry Summary - There are currently 15 existing drug registration numbers for Gefitinib tablets in China, with projected sales of 263 million yuan in 2024 [1]