Core Viewpoint - Bayer's new product, Thiamidol 630, represents a significant milestone in the integration of global research and local market needs, showcasing a model of innovation that combines "German precision" with "Shanghai speed" [3][4][24]. Group 1: Product Development and Market Integration - Thiamidol 630 is the second new whitening ingredient approved in China and the first to receive approval after the implementation of the Cosmetics Supervision and Administration Regulations in 2021, marking a significant achievement in localizing global innovations [5][24]. - The product's development process, referred to internally as the "211 project," took nine years and reflects Bayer's commitment to thorough research and development [5][11]. - The unveiling of the Chinese trademark for Thiamidol 630 signifies Bayer's deepening integration into the Chinese market and its role as a key node in the company's global research network [5][11][23]. Group 2: Research and Innovation Strategy - Bayer's strategy emphasizes a dual approach of "global innovation + local insight," which drives the company's research and development efforts in China [18][21]. - The company has established a comprehensive research framework that includes basic research, clinical validation, and market transformation, creating a closed-loop system that enhances product efficacy and safety [18][21][26]. - Thiamidol 630's clinical data shows significant improvements in skin conditions after 12 weeks of use, demonstrating its effectiveness and safety compared to traditional whitening agents [16][18]. Group 3: Industry Impact and Future Directions - The successful launch of Thiamidol 630 serves as a model for international brands navigating the Chinese regulatory landscape, providing a pathway for future cross-border research collaborations [26][27]. - The product's introduction is expected to shift industry standards towards more scientifically validated approaches in skincare, moving away from traditional models that rely on less effective ingredients [26][27]. - Bayer's commitment to rigorous scientific validation and consumer safety positions it as a leader in the skincare industry, reinforcing its brand strength and market presence in China [27][28].

2025 年，提安明多630的产业化步伐持续加速：2月，拜尔斯道夫旗下的优色林将上海定为全球首发 地，发布以提安明多®630为核心成分的第二代光引精华及系列产品。因为彼时还未拿到批文，当时是 以跨境购商品进行销售。但很快，优色林拿到特证，5月在国内以大贸形式全面上市，而集团旗下的妮 维雅全新630系列获得国妆特进字批件，9月实现大贸渠道全面上市。 记者采访了解到，前述新品在短时间内落地，得益于今年2月发布的《支持化妆品原料创新若干规 定》，该政策通过建立新原料和关联产品同步申报工作机制，大大缩短特殊类产品的备案期，加速推进 使用新原料的产品上市。 公司方面也表示，正是受益于相关化妆品政策的东风，这款祛斑美白专利成分及系列产品才能在短时间 里在中国市场顺利完成"研发—审评—投产—中文商标发布"的全链路落地。 从原料研发到产品上市，时间缩短了。 今年以来，陆续出台的化妆品相关政策，为外资企业在中国实现新原料快速转化提供了支持，也加深了 它们深耕中国的决心。 9月末，上海经信委颁布《关于进一步促进化妆品产业高质量发展的若干措施》。"其中有一系列的政策 和一些补贴的方式，为（化妆品）企业提供了资金的支持，而我们的提安 ...

Core Insights - The article highlights the development of the cosmetics industry in Qingpu District, leveraging strategic advantages from the Yangtze River Delta integration, the China International Import Expo, and the Hongqiao Business District to create a comprehensive "R&D - Production - Marketing - Logistics" ecosystem [2][4]. Group 1: Industry Development - The conference focused on "Supporting the High-Quality Development of the Cosmetics Industry in Qingpu District," showcasing innovative achievements and future prospects of the cosmetics sector in the Yangtze River Delta integration demonstration zone [2]. - Qingpu District is committed to fostering an innovative environment, enhancing the entire value chain from R&D to manufacturing, and creating a high-resilience industrial ecosystem [2][5]. Group 2: Regulatory and Collaborative Efforts - The approval of the new whitening and freckle-removing ingredient, TIANMINGDUO®630, marks a significant milestone for the Chinese cosmetics industry, being the first new ingredient approved by the National Medical Products Administration after the implementation of the Cosmetics Supervision and Administration Regulations [4]. - The successful development and approval process involved collaboration between various stakeholders, including the Qingpu District government, which provided tailored support for enterprises [4]. Group 3: Future Directions - Qingpu District plans to deepen collaboration among government, enterprises, and research institutions, optimize the business environment, and accelerate the gathering of high-end resources to advance the cosmetics industry towards scientific and high-end development [5].

Core Viewpoint - The "2025 Yangtze River Delta Integration Demonstration Zone Shanghai Qingpu Cosmetics Industry Innovation Development Conference" highlighted the release of the "Qingpu Cosmetics Industry White Paper," showcasing the region's commitment to high-quality development in the cosmetics sector through innovation and collaboration [1][3]. Group 1: Industry Development - Qingpu District has leveraged the strategic advantages of the Yangtze River Delta Integration Demonstration Zone, the China International Import Expo, and the Hongqiao Business District to establish a complete "R&D—Production—Marketing—Logistics" closed-loop ecosystem, demonstrating strong innovation capabilities and market competitiveness [3]. - The conference aimed to build a collaborative platform for government, enterprises, and research institutions, showcasing the innovative achievements and future vision of the Qingpu cosmetics industry [3]. Group 2: Government and Industry Collaboration - Qingpu District is focused on creating a scientific, standardized, and efficient development environment for the cosmetics industry, emphasizing the construction of a resilient industrial ecosystem from R&D to manufacturing [3]. - The Shanghai Municipal Economic and Information Commission highlighted cosmetics as one of the six key industries for development, crucial for enhancing the city's industrial capabilities and soft power [3]. Group 3: Product Innovation - The newly approved whitening and freckle-removing ingredient, TIANMINGDUO®630, represents a historic breakthrough for the Chinese cosmetics industry, marking the first new ingredient approved by the National Medical Products Administration since the implementation of the Cosmetics Supervision and Administration Regulations [5]. - The successful development and approval of TIANMINGDUO®630 were facilitated by the "spillover effect" from the China International Import Expo, with key milestones occurring in Qingpu, illustrating a complete "full-link innovation story" [5]. Group 4: Future Outlook - Qingpu District plans to continue enhancing collaboration among government, enterprises, and research institutions, optimizing the business environment, and accelerating the gathering of high-end resources to advance the cosmetics industry towards scientific and high-end development [6].

Core Insights - Bayer's new patented ingredient, Tiannmingduo®630, is the first inhibitor based on human tyrosinase screening, aimed at suppressing melanin production from the source [1][3] - The introduction of the Chinese trademark signifies the ingredient's localization for Chinese consumers and strengthens intellectual property protection [3] - Tiannmingduo®630 is a result of over 20 years of research and development, reflecting the strategy of "driving global R&D with Chinese demand" [3] Product Launch and Market Strategy - Bayer has launched 12 products containing Tiannmingduo®630, covering various skincare segments including mass market, dermatological, high-end skincare, and professional medical aesthetics [1] - The ingredient received approval as the first new whitening ingredient under the Cosmetic Supervision and Administration Regulations, indicating a significant regulatory milestone [4] - The second-generation light-activated essence featuring Tiannmingduo®630 was globally launched in Shanghai, marking a transition from cross-border to local sales [4] Research and Development - The development of Tiannmingduo®630 involved overcoming challenges in expressing recombinant human tyrosinase over 15 years, screening from over 50,000 molecules [3] - The ingredient has completed a full set of toxicological safety assessments and has been published in multiple SCI papers [3] Regulatory and Industry Support - The ingredient's market entry was facilitated by supportive policies, including the establishment of a synchronized application mechanism for new raw materials and related products [4] - Bayer emphasizes data-driven claims in the competitive beauty market and intends to combat false advertising related to unverified ingredients [4]