Group 1 - The core point of the article highlights the significant price drop in various vaccines in the domestic market, with the three-valent flu vaccine priced at only 5.5 yuan, marking a new low for public flu vaccines [1] - The price of the two-valent HPV vaccine from Watson Bio has plummeted from 245 yuan per dose in 2022 to 27.5 yuan per dose in 2025, a decrease of nearly 90% [1] - The nine-valent HPV vaccine from Wantai Bio is priced at 499 yuan per dose, significantly lower than imported products, prompting the latter to engage in promotional activities to lower prices [1] Group 2 - The sharp decline in vaccine prices is expected to reduce public vaccination costs, theoretically improving vaccine accessibility and uptake [2] - Concerns have been raised regarding the potential impact of such low prices on public trust in vaccine quality, with fears that low-cost vaccines may compromise safety and effectiveness [2] - The public's skepticism may lead to a mindset of avoiding vaccinations altogether due to perceived risks associated with low-priced vaccines [2]

HPV疫苗价格降至一杯奶茶钱，流感疫苗甚至跌至个位数……在疫苗行业愈发"内卷"的当下，中国疫苗 行业协会发声，倡议协会会员坚决抵制无序低价竞争，严禁以低于成本的报价参与竞标。目前，中国疫 苗行业协会会员达到334家，主要疫苗厂商均涵盖在内。 疫苗行业的价格战，也使相关企业业绩出现承压，今年前三季度，A股14家疫苗企业中，有10家企业归 属净利润同比出现下滑，其中万泰生物、百克生物、智飞生物等更是由盈转亏。在业内人士看来，上述 倡议若能有效落实，有助于遏制恶性价格战，稳定市场价格环境，从而减少企业利润压力，促进资源向 研发和创新倾斜。 严禁以低于成本报价参与竞标 11月19日，中国疫苗行业协会发布《关于反对"内卷式"竞争 促进疫苗及其相关生物制品行业高质量发 展的倡议》。中国疫苗行业协会表示，该倡议旨在通过强化自律、鼓励创新，助力行业打破"内卷"，构 建健康有序的良性生态，共同开启以质量、安全、创新为核心的行业发展新篇章。 倡议提到，中国疫苗行业协会全体会员须严格遵循《中华人民共和国疫苗管理法》《中华人民共和国价 格法》，严格遵守行业自律公约，坚持公平、合法、诚实信用原则，以生产经营成本与市场供求状况为 定价基 ...

Core Viewpoint - The Chinese Vaccine Industry Association has issued an initiative to combat chaotic price competition in the vaccine industry, advocating for self-discipline and innovation to promote high-quality development in the sector [4][5]. Group 1: Industry Challenges - The vaccine industry is experiencing intense price wars, with the price of the bivalent HPV vaccine dropping to as low as 27.5 yuan per dose, and flu vaccines reaching as low as 5.5 yuan per dose [7][9]. - In the first three quarters of this year, 71.43% of A-share vaccine companies reported a decline in net profit, with notable losses from companies like Wantai Biological Pharmacy and BCG Biological [8][9]. Group 2: Association's Initiative - The initiative calls for all members of the association to adhere to the Vaccine Administration Law and the Price Law, ensuring fair and legal pricing based on production costs and market demand [4][5]. - The association emphasizes the need to resist disorderly low-price competition and prohibits bidding below cost, aiming to stabilize market prices and improve product quality [4][6]. Group 3: Long-term Outlook - If effectively implemented, the initiative could lead to a more orderly competitive landscape, enhancing the industry's sustainable development and improving the safety and efficacy of vaccine products [5][6]. - Companies are encouraged to increase R&D investment to develop differentiated products, optimize production processes, and explore international markets to mitigate risks and enhance competitiveness [10].