今年，港股创新药势不可挡，成为资本市场的重磅热点。 数据最具说服力，港股创新药概念指数从年初至今涨幅已超100%，不仅大幅跑赢恒生指数，更以扎实 的上涨态势重塑了市场对创新药产业的信心。 这轮行情的背后并非偶然，机构普遍认为，其核心驱动力是政策、基本面、资金面的三重共振，而非短 期利好的临时拉动。譬如，7月国家医保局首次将具备高临床价值但暂未纳入医保的创新药纳入商保支 付范围，为创新药开辟了更多元的变现路径；产业端的出海进程也取得历史性突破，大额BD合作频频 落地，整个创新药产业的活力正加速释放。 在行业整体向好的背景下，基金经理对下半年行情的预判也更为积极，更明确指出当前正是中长期布局 创新药板块的重要窗口期。例如，永赢医药创新智选基金经理储可凡与单林便一致认为，创新药是当前 医药领域确定性最强、置信度最高、增长空间最大的核心板块。随着国内企业持续产出优秀临床数据， 叠加出海能力不断强化，未来商业化兑现路径将愈发清晰，业绩落地节奏也会逐步加快，长期成长逻辑 坚实。 正是在这样的产业红利期，近日，眼科创新药企兆科眼科发布2025年中期财报，阿托品滴眼液、环孢素 A眼凝胶、贝伐单抗注射液三大重磅眼药均已提交上市 ...

Core Viewpoint - Zhaoke Ophthalmology is considered an undervalued innovative ophthalmic drug company, with significant potential for growth as it approaches a clinical drug harvest period and has seen a stock price increase of approximately 140% this year, despite a low price-to-book ratio of less than 1 [4][15]. Product Pipeline and Market Potential - Zhaoke Ophthalmology has a comprehensive pipeline focusing on three main products: NVK002 for myopia control, a modified cyclosporine A eye gel for moderate to severe dry eye syndrome, and TAB014 for wet age-related macular degeneration (wAMD) [5][10][11]. - The NVK002 product, a low-concentration atropine eye drop, has received significant regulatory attention, with a simplified new drug application accepted and a new drug listing application approved for the 0.02% concentration [5][7]. - The market for myopia treatment is substantial, with over 40 million children in China being potential users, indicating a large growth opportunity for NVK002 [7][9]. Competitive Landscape - The competition for NVK002 is intense, with other companies like Xingqi Eye Medicine already having launched similar products. Zhaoke aims to differentiate itself by enhancing patient compliance and addressing the stability issues of atropine [8][9]. - The modified cyclosporine A eye gel has shown promising clinical results, with a patient compliance rate of 98.94%, and is expected to receive faster approval due to proactive communication with regulatory authorities [10][11]. Future Outlook - Zhaoke Ophthalmology aims to have a total of 12 products on the market within the next 18 months, which would significantly enhance its influence in the ophthalmic field [14][15]. - The company has also received orphan drug designation from the FDA for a treatment for retinoblastoma, indicating its commitment to expanding its product offerings [12]. - The CEO expressed confidence in the company's future, emphasizing the importance of timely product approvals and the potential for market growth in various ophthalmic conditions [17].

2023年10月， 药渡数据库 刊文称，据预计到2030年中国干眼症药物市场规模将大幅增长至 67亿美元 。 干眼症市场具有巨大的潜力和不断增长的患者需求，特别是在中国，随着人口老龄化和现代生活方式的影响，干眼症的患病率和市场规模预计将持续增长。 同时， 患者对于更有效和便捷治疗方式的需求也在不断提升。 干眼常见治疗方式 01 干眼症发病原理 泪膜的结构和功能对于维持眼睛健康至关重要，由 粘 蛋白层、水液层和脂质层构成。 粘蛋白层提供泪膜与眼球表面的粘附力 ，使泪膜能够稳定地附着在眼表，防止泪膜过早破裂。 水液层保持角膜和结膜的湿润 ，提供必要的营养和氧气，帮助清除 眼表的异物和细胞代谢产物。 脂质层减少泪液与空气的接触 ，降低泪液的蒸发速率，维持泪膜的稳定性。 干眼（Dry Eye Disease, DED）是多因素引起的慢性疾病，由泪液的质、量及动力学异常导致的泪膜不稳定或眼表微环境失衡，可伴有眼表炎性反应、组织损伤及 神经异常，造成眼部多种不适症状和/或视功能障碍。 在2007年第1次国际干眼工作小组报告（DEWS 1）中， "干眼症"就已被正式确定为"干眼"，并定义为一种疾病。 根据《国人干眼多中心大 ...