Core Viewpoint - The company, Kelun Pharmaceutical, announced that its subsidiary, Sichuan Kelun Botai Biopharmaceutical Co., Ltd., received approval from the National Medical Products Administration (NMPA) for its antibody-drug conjugate (ADC) A166 (also known as Trastuzumab deruxtecan) for the treatment of adult patients with unresectable or metastatic HER2-positive breast cancer who have previously received one or more anti-HER2 therapies [1] Group 1 - The ADC A166 targets the human epidermal growth factor receptor 2 (HER2) [1] - The approval is specifically for patients with unresectable or metastatic HER2-positive breast cancer [1] - The indication is for those who have previously undergone treatment with one or more anti-HER2 drugs [1]

Core Viewpoint - Kolon Biotech-B (06990) reported a significant decline in revenue for the six months ending June 30, 2025, with a 31.3% year-on-year decrease, leading to a loss attributable to equity shareholders of RMB 145 million [1] Financial Performance - The company achieved revenue of RMB 950 million, down 31.3% year-on-year [1] - Research and development expenses amounted to RMB 612 million, a decrease of 6.3% year-on-year [1] - The loss attributable to equity shareholders was RMB 145 million, with a loss per share of RMB 0.64 [1] Product Development and Commercialization - The company has received marketing approvals for sac-TMT (Jiatailai), Tagolizumab (Ketailai), and Cetuximab N01 (Datailai) and has commenced commercialization [1] - The company anticipates launching Botuzumab (Shutailai) in the Chinese market in the second half of 2025, pending regulatory communication and approval [1] - Total commercial sales for the first half of 2025 reached RMB 309.8 million, with Jiatailai accounting for 97.6% of sales [1] Accounts Receivable Management - All accounts receivable from drug sales were collected within the payment period, indicating efficient and stable cash flow management [1]