Core Viewpoint - A team of scientists, including NASA researchers, has identified critical gaps in NASA's development of biological life support systems, which may hinder the U.S. in long-term manned space exploration and habitation, especially in competition with China [1][2]. Group 1: Current State of U.S. Space Life Support Systems - The U.S. space life support systems, including those used on the International Space Station, rely on supply missions for essential resources like water and food [1]. - Long-term manned missions beyond Earth's orbit face significant costs and logistical challenges due to reliance on supply launches, alongside safety concerns regarding radiation and microgravity effects on human health [2]. Group 2: Biological Life Support Systems (BLSS) - Biological life support systems (BLSS) are seen as a superior solution for long-term deep space missions, utilizing biological processes to create a sustainable closed-loop environment for food, water, and oxygen [2]. - The lack of available BLSS technology and systems is currently limiting the goals of manned lunar exploration programs [2]. Group 3: Historical Context and Funding Issues - NASA previously focused on biological regeneration methods in the 1990s, which led to the development of sustainable agricultural systems for space exploration [5]. - A significant shift in focus and budget cuts in 2004 led to the dismantling of the BIO-Plex project, which aimed to test life support systems for future space missions [5][6]. - Since the early 2000s, U.S. support for biological regeneration life support research has diminished, while China has actively advanced this area over the past two decades [6]. Group 4: China's Advancements in Space Exploration - China has established a strong position in biological life support technology, exemplified by projects like "Moon Palace 1," which is a closed ecological system for lunar base life support research [6]. - Recent plans from the China National Space Administration (CNSA) indicate that China has surpassed the U.S. and its allies in emerging technologies and capabilities for establishing lunar or Martian habitats [6][9]. Group 5: Future Implications and Challenges - The U.S. space program faces years of challenges in rebuilding the necessary facilities and infrastructure for biological life support systems [9]. - Despite ongoing research in the field, including private sector initiatives and international collaborations, there are concerns about funding and political support for these projects in the U.S. [11][12].