Core Viewpoint - Goldman Sachs has slightly reduced its net profit forecasts for Kanglong Chemical (03759) for the years 2025 to 2027, while maintaining a "Buy" rating for its H-shares and a neutral rating for its A-shares [1] Group 1: Financial Performance - Kanglong Chemical's Q3 revenue reached 3.65 billion RMB, representing a year-on-year growth of 13.4% and a quarter-on-quarter growth of 9.1%, slightly exceeding Goldman Sachs' previous expectation of 3.48 billion RMB [1] - The adjusted non-IFRS net profit margin improved to 12.9%, compared to 11.3% in Q1 and 12.2% in Q2, benefiting from increased utilization and operational leverage [1] Group 2: Management Guidance - The management has raised its full-year revenue growth guidance from 10%-15% to 12%-16%, indicating a Q4 year-on-year growth of 6%-20% [2] - The management remains confident in achieving the revised guidance, citing strong growth in CMC orders, ongoing capacity expansion, and improved core business profit margins [2] Group 3: Strategic Outlook - Continued investment in the biopharmaceutical sector and strategic acquisitions are expected to strengthen Kanglong Chemical's growth and leadership position in the CDMO field [2]

Investment Rating - The report maintains a "Buy" rating for the company, with an increased target price of HKD 30 for the Hong Kong stock and RMB 39.6 for the A-share [10][19]. Core Insights - The company has experienced a significant acceleration in new orders, particularly in the laboratory services segment, leading to an upward revision of the full-year revenue growth guidance to 12%-16% [3][10]. - The acquisition of Bai Aode is expected to enhance the company's service capabilities in the laboratory services sector, attracting more clients and projects [2][9]. - The revenue for Q3 2025 was approximately RMB 3.64 billion, reflecting a year-on-year increase of 13.4% and a quarter-on-quarter increase of 9.1%, aligning with expectations [2][3]. Summary by Sections Revenue and Profitability - For the first nine months of 2025, the overall new orders increased by over 13% year-on-year, with laboratory services showing a growth rate of over 12% [3][4]. - The CMC segment achieved a revenue growth of 12.7% year-on-year and 29.6% quarter-on-quarter in Q3 2025, driven by strong new orders and project deliveries [9][10]. - The gross margin for Q3 2025 was 34.3%, stable year-on-year and up 0.6 percentage points quarter-on-quarter [2][3]. Client Contributions - The top 20 pharmaceutical companies contributed a revenue growth of 22.2% year-on-year in Q3 2025, despite a slight slowdown from the first half of the year [4][10]. - The management indicated that the strategic expansion with top clients has led to impressive growth across CMC, laboratory services, and bioscience services [4][9]. Future Outlook - The company anticipates that the recovery of overseas financing and a strong performance in the Chinese capital market will lead to a more pronounced recovery among small and medium clients in 2026 [3][10]. - The report projects a slight adjustment in the company's adjusted net profit for 2025E to RMB 1.664 billion, reflecting a year-on-year decrease of 7.2% [11][12].

Core Viewpoint - 康龙化成 is experiencing a positive trend in its CMC service gross margin, with expectations for continued growth in the upcoming quarters [1] Financial Performance - The gross margin for CMC services in Q3 2025 is reported at 34.6%, reflecting a 4 percentage point increase quarter-over-quarter [1] - The company anticipates that the gross margin for Q4 will continue to improve sequentially, with the full-year gross margin expected to be slightly above 33%, compared to the same period last year [1] Capital Expenditure - The projected capital expenditure for 2025 is over 2 billion yuan, primarily allocated for laboratory services in China and small molecule CDMO capacity expansion, including new capacity in Beijing and the second phase project in Shaoxing [1] - Future capital expenditures are expected to remain at similar levels, with operating cash flow sufficient to cover these expenditures [1] Innovation and Technology Investment - 康龙化成 is committed to ongoing investments in new technology areas, including organoids and AI [1] - The company aims to maintain sustainable positive free cash flow [1]

Summary of the Conference Call for 康龙化成 (Crown Bioscience) Company Overview - 康龙化成 reported a revenue of 10.086 billion yuan for the first three quarters of 2025, representing a year-on-year growth of 14.4% [2][4] - Adjusted net profit for the same period was 1.227 billion yuan, up 10.8% year-on-year [2][4] - The company has raised its full-year revenue guidance to a growth of 12%-16% [5][10] Key Business Segments Performance Laboratory Services - Revenue for the laboratory services segment in the first three quarters was 6.004 billion yuan, a 15% increase year-on-year [2][6] - Gross margin maintained around 45% with new orders growing over 12% [2][6] - In Q3 alone, revenue was 2.111 billion yuan, a 3.7% increase from the previous quarter and a 14.3% increase year-on-year [6] CMC Services - CMC services generated 2.293 billion yuan in revenue for the first three quarters, a 16% year-on-year increase [2][6] - Gross margin for this segment was 34.6%, with new orders increasing approximately 20% [2][6] - Q3 revenue was 903 million yuan, showing a significant 29.6% quarter-on-quarter increase and a 12.7% year-on-year increase [6][17] Clinical Services - Clinical services revenue for the first three quarters was 1.44 billion yuan, up 10.3% year-on-year [2][6] - Q3 revenue was 501 million yuan, a 1.7% increase from the previous quarter and an 8.2% increase year-on-year [6][22] Macromolecule and CGT Services - Revenue for this segment was 336 million yuan in the first three quarters, an 8% year-on-year increase [2][6] - Q3 revenue was 125 million yuan, a 10.6% quarter-on-quarter increase and a 25.1% year-on-year increase [6] Customer and Geographic Performance - North American clients accounted for 64% of total revenue, with multinational corporations contributing 18% and Chinese clients 15% [7][8] - The company serves 15 out of the top 20 global pharmaceutical companies, which contributed 18% of total revenue, showing a strong year-on-year increase of 37.9% [7] M&A Activities - 康龙化成 plans to acquire Wuxi Baode Biological Science to enhance its structural biology capabilities and improve early antibody discovery and optimization [9] Future Outlook - The company expects continued growth driven by increasing health demands and technological innovations, with a positive outlook for both overseas and domestic client demands [10][11] - The anticipated capital expenditure for 2025 is over 2 billion yuan, focusing on laboratory and CDMO capacity expansion [21] Competitive Landscape and Strategy - The laboratory R&D market remains competitive, but 康龙化成 is increasing its market share, particularly in the biological sciences segment, which has grown over 15% [15] - The company is committed to enhancing automation and AI capabilities to improve R&D efficiency and is focusing on long-term growth in new segments like macromolecules and gene cell therapy [27][28] Recruitment Plans - 康龙化成 is increasing recruitment efforts in 2025 to support the growth in laboratory service orders [24][26] Conclusion - 康龙化成's overall performance in 2025 is optimistic, with significant growth across various segments and a strategic focus on enhancing capabilities through acquisitions and technological investments [25]

Investment Rating - The investment rating for the company is "Buy" for both A and H shares, maintained from previous assessments [7]. Core Insights - The company has demonstrated steady performance with a revenue of 10.086 billion RMB and a non-IFRS adjusted net profit of 1.227 billion RMB for the first three quarters of 2025, reflecting year-on-year growth of 14.4% and 10.8% respectively [1]. - The company has raised its revenue growth guidance for 2025 from 10-15% to 12-16%, indicating strong confidence in its growth prospects [1]. - The acquisition of Wuxi Bai'ao is expected to enhance the company's integrated service capabilities and international reach, aligning with its strategic focus on a comprehensive, integrated, and multi-therapy approach [3][4]. Summary by Sections Financial Performance - For the first three quarters of 2025, the company reported a gross margin of 34.2%, an increase of 0.4 percentage points year-on-year, supported by scale effects and improved capacity utilization in its CMC business [1]. - The net cash flow from operating activities reached 2.436 billion RMB, marking a year-on-year increase of 37.6% [1]. - The company’s new order intake grew by over 13% year-on-year, with a notable acceleration in the third quarter [2]. Business Segments - The laboratory services segment, as the flagship business, generated 6.004 billion RMB in revenue, up 15.0% year-on-year, with new orders increasing by over 12% [2]. - The CMC segment reported revenue of 2.293 billion RMB, reflecting a year-on-year growth of 16.0%, with new orders increasing by approximately 20% [2]. - The clinical CRO segment achieved revenue of 1.440 billion RMB, up 10.3% year-on-year, while the large molecules and CGT segment saw revenue of 336 million RMB, an 8.1% increase [2]. Acquisition Details - The company plans to acquire 82.54% of Wuxi Bai'ao for approximately 1.346 billion RMB, which is positioned as a leading CRO in structural biology [3]. - The acquisition is expected to create strong synergies, leveraging Bai'ao's advanced capabilities in structural biology and protein preparation, enhancing the company's service offerings [4]. Profit Forecast and Valuation - The projected net profits for the company from 2025 to 2027 are 1.729 billion RMB, 2.105 billion RMB, and 2.529 billion RMB respectively, with slight upward adjustments from previous estimates [5]. - The company is assigned a PE ratio of 37x for A shares and 26x for H shares in 2026, with target prices set at 43.81 RMB and 33.69 HKD respectively [5].

Investment Rating - The report maintains a "Buy" rating for the company and raises the target price for both the Hong Kong and A-share listings to HKD 27.0 and RMB 39.0 respectively [5][9]. Core Insights - The company reported a revenue of RMB 3.342 billion in Q2 2025, reflecting a year-on-year increase of 13.9% and a quarter-on-quarter increase of 7.9%, aligning closely with previous profit forecasts [1]. - The overall new order growth for the first half of 2025 continued at a rate of over 10% year-on-year, with the company maintaining its full-year revenue growth guidance of 10%-15% [4]. - The top 20 pharmaceutical companies showed strong revenue growth of 48% year-on-year in the first half of 2025, with expectations for continued growth in the second half [2]. Summary by Sections Financial Performance - In Q2 2025, the adjusted net profit attributable to the parent company was RMB 406 million, up 15.6% year-on-year and 16.3% quarter-on-quarter, slightly below expectations due to higher-than-expected losses from non-operating items [1]. - The gross margin for Q2 2025 was 33.7%, remaining stable year-on-year and quarter-on-quarter, while the adjusted net profit margin was 11.7%, showing a slight increase [1]. Revenue Breakdown - Laboratory services revenue grew by 15.2% year-on-year and 9.6% quarter-on-quarter, driven by strong growth in biological science services [3]. - CMC services revenue increased by 17.4% year-on-year and 0.5% quarter-on-quarter, primarily due to growth from top 20 pharmaceutical clients [3]. - Clinical research services revenue rose by 8.9% year-on-year and 10.0% quarter-on-quarter, although margins declined due to competitive pricing in the domestic market [3]. Market Outlook - The company expects continued revenue growth in the second half of 2025, although year-on-year growth may moderate due to a high base in the second half of 2024 [4]. - The report highlights that laboratory services and CMC will remain the main drivers of revenue growth, with profit margins expected to improve in the latter half of the year [4].

Core Viewpoint - 康龙化成 reported a strong performance in the first half of 2025, with a revenue increase of 14.9% year-on-year, driven by significant growth in orders and robust demand from top pharmaceutical clients [1][4]. Financial Performance - The company achieved a revenue of 6.441 billion yuan in the first half of 2025, reflecting a year-on-year growth of 14.9% [4]. - The net profit attributable to shareholders was 701 million yuan, a decrease of 37.0% year-on-year, primarily due to last year's substantial gains from the disposal of PROTEOLOGIX, INC. shares [4]. - Adjusted net profit under non-IFRS standards was 756 million yuan, representing a year-on-year increase of 9.5% [4]. - New orders signed in the first half of 2025 increased by over 10% year-on-year [4]. Client and Market Dynamics - Revenue from MNC (Top 20 pharmaceutical companies) clients grew significantly by 48.0% year-on-year, attributed to the maturity of CMC project pipelines and deepened collaboration in laboratory services [2][4][9]. - The company added over 480 new clients, with active clients exceeding 2,600 [4]. Strategic Development - 康龙化成 is committed to its long-term development strategy, having established 21 R&D centers and production bases globally, including in China, the UK, and the US [5]. - The company has a workforce of 22,908 employees, with over 1,700 based overseas, and more than 90% of employees engaged in R&D, production, and clinical services [5]. Business Segment Performance - Laboratory services generated revenue of 3.89 billion yuan, up 15.5% year-on-year, with a gross margin of 45.2% [6]. - CMC (small molecule CDMO) services achieved revenue of 1.39 billion yuan, reflecting an 18.2% increase year-on-year, with a gross margin of 30.5% [6]. - Clinical research services reported revenue of 940 million yuan, a year-on-year growth of 11.4% [7]. - Revenue from large molecule and cell & gene therapy services was 210 million yuan, showing a slight increase of 0.1% [8]. Technological and Operational Advancements - The company is enhancing its AI capabilities by integrating clinical data resources with AI technology, aiming to improve service efficiency [6]. - Continuous investments in various technologies, including continuous flow technology and high-throughput experimentation, are being made to support the CMC service segment [11]. Industry Outlook - The company perceives good resilience in overseas client demand, while domestic client demand is expected to gradually recover [3][12].

Core Viewpoint - The overall performance of the company is steadily growing, with laboratory services and CMC services contributing the main incremental growth [2] Group 1: Financial Performance - The revenue from large multinational clients has significantly increased, indicating a positive trend in demand [2] - There is a noticeable recovery in demand from Chinese clients, suggesting a potential market rebound [2] Group 2: Industry Context - The company faces risks related to geopolitical uncertainties and tariffs, which could impact future performance [2] - The investment and financing in the biopharmaceutical industry are below expectations, posing a challenge for growth [2] - The competitive landscape in the industry is intensifying, which may affect market positioning [2]

Investment Rating - The report assigns a "Buy" rating for Kanglong Chemical (300759) based on its performance and growth potential [13]. Core Views - The overall performance of the company shows steady growth, with laboratory services and CMC services contributing significantly to revenue increases [2][3]. - The company maintains a full-year revenue growth guidance of 10-15% for 2025, supported by stable new order growth across its four main business segments [3]. Summary by Sections Financial Performance - In H1 2025, the company achieved revenue of 6.441 billion yuan, a year-on-year increase of 14.9%, and a net profit attributable to shareholders of 700 million yuan, a decline of 37.0% [1]. - The adjusted net profit attributable to shareholders was 756 million yuan, up 9.5% year-on-year, with operating cash flow increasing by 28.06% to 1.408 billion yuan [1]. Business Segments - **Laboratory Services**: Revenue reached 3.892 billion yuan, up 15.5% year-on-year, with a gross margin of 44.9%, an increase of 0.9 percentage points. New orders in this segment grew by over 10% [2]. - **CMC Services**: Revenue was 1.390 billion yuan, an 18.2% increase year-on-year, with a gross margin of 30.2%, up 2.4 percentage points. New orders in this segment grew by approximately 20% [2]. - **Clinical Research Services**: Revenue was 939 million yuan, an 11.4% increase year-on-year, with a gross margin of 12.3%, slightly down by 0.3 percentage points [3]. - **Large Molecule and Cell & Gene Therapy Services**: Revenue was 211 million yuan, remaining stable year-on-year, but with a gross margin of -54.7%, indicating losses due to high operational costs [3]. Customer and Regional Analysis - The company added over 480 new clients in H1 2025, contributing 128 million yuan, while existing clients generated 6.313 billion yuan, accounting for 98.01% of total revenue [4]. - Revenue from the top 20 global pharmaceutical companies was 1.168 billion yuan, a significant increase of 47.98% year-on-year [5]. - Revenue distribution by region showed North America contributing 4.073 billion yuan (up 11.02%), Europe 1.234 billion yuan (up 30.52%), and China 973 million yuan (up 15.48%) [5]. Financial Projections - Revenue projections for 2025-2027 are 13.865 billion yuan, 15.591 billion yuan, and 17.560 billion yuan, respectively, with net profits of 1.718 billion yuan, 1.985 billion yuan, and 2.302 billion yuan [7]. - The expected EPS for the same period is 0.97 yuan, 1.12 yuan, and 1.29 yuan, with corresponding P/E ratios of 31.16, 26.96, and 23.25 [7].

Financial Performance - Revenue for Q2 2025 reached RMB 3,342 million, a 7.9% increase from Q1 2025 and a 13.9% increase year-over-year from Q2 2024 [14] - Net profit attributable to shareholders for Q2 2025 was RMB 396 million, a 29.5% increase from Q1 2025 but a 55.2% decrease year-over-year from Q2 2024 [14] - Non-IFRS adjusted net profit for Q2 2025 was RMB 406 million, reflecting a 16.3% increase from Q1 2025 and a 15.6% increase year-over-year [14] Revenue Breakdown - For 1H 2025, total revenue was RMB 6,441 million, a 14.9% increase compared to 1H 2024 [15] - New orders increased by over 10% year-over-year, with revenue from top 20 pharmaceutical companies growing by 48% [15] - Revenue composition: 88% from domestic delivery and 12% from overseas delivery [18] Client and Market Insights - Active clients exceeded 2,600, including over 480 new clients, with significant contributions from the top 20 pharmaceutical companies [16] - Revenue growth from North American clients was 11%, European clients 30.5%, and Chinese clients 15.5% [19] - The company maintains a target of 10-15% revenue growth for the full year 2025 [55] ESG and Sustainability Initiatives - The company achieved an AA rating in the latest MSCI ESG assessment [24] - It has joined the United Nations Global Compact and aims for the highest ESG ratings in the Asia-Pacific region by 2025 [28][29] - Efforts include achieving 100% renewable electricity usage in some facilities and expanding information security management systems [26] Operational Highlights - The company participated in 795 drug discovery projects and has a robust pipeline for long-term growth [16] - Clinical research services included 1,027 projects, with 89 in Phase III trials [36] - The company is enhancing its AI capabilities through partnerships and new technology integrations [16]