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2026年创新药行业年度投资策略:看好工程师红利下创新突围
ZHESHANG SECURITIES· 2025-11-21 07:45
Group 1 - The report highlights the "engineer dividend" period for China's innovative drug industry, indicating that local innovations have gained full recognition from multinational corporations (MNCs) [4][5][53] - The report emphasizes the strong performance of various Chinese biotech stocks, with notable price increases observed in companies like Rongchang Biopharmaceutical (+199%) and Mawei Biopharmaceutical (+124%) in the A-share market [4][16] - The report identifies a significant increase in the number of first-in-class (FIC) drugs entering clinical trials in China, from only 9 in 2015 to an expected 120 in 2024, with China's global share of FIC drugs exceeding 30% [4][22] Group 2 - The report discusses the leading position of Chinese companies in the antibody-drug conjugate (ADC) sector, with over 50% global pipeline share in key targets such as HER2 and TROP2 [25][32] - It notes that two Chinese ADC drugs have entered the top ten global upfront payment rankings, indicating strong valuation potential for local innovations [30][31] - The report highlights the anticipated growth in bispecific antibodies (bsAbs), with Chinese companies dominating the top five global upfront payments for related assets [37][41] Group 3 - The report recommends several companies with significant global single product potential, including Kolon Biotech and Innovent Biologics, while also highlighting others like 3SBio and BeiGene as companies to watch [6][52] - It emphasizes the potential for substantial global pricing power for assets, particularly for companies like Rongchang Biopharmaceutical and Zai Lab, which are expected to see continued clinical data readouts [6][52] - The report suggests that companies like Innovent Biologics and Rongchang Biopharmaceutical are likely to turn profitable, with expectations of improved financial performance in the coming years [6][52]
港股异动|君实生物(01877)一度拉升超11% PD-(L)1/VEGF赛道景气度提高
Jin Rong Jie· 2025-08-08 04:05
Group 1 - The stock of Junshi Biosciences (01877) experienced a significant increase, rising over 11% recently, following a previous surge of over 33% on August 5 [1] - As of the latest report, the stock is up 8.14%, trading at HKD 29.5, with a trading volume of HKD 531 million [1] - Junshi Biosciences completed a placement of 41 million new shares on June 20, raising a net amount of approximately HKD 1.026 billion, with 70% allocated for innovative drug research and 30% for general corporate purposes [1] Group 2 - The company is focusing on the development of innovative drugs, including PD-1/VEGF bispecific antibodies, EGFR/HER3 ADC, and PD-1/IL-2 fusion proteins [1] - According to Fangzheng Securities, JJS207 has significant business development (BD) potential, as international pharmaceutical companies are interested in PD-1/VEGF products [1] - Open Source Securities noted that by May 2025, only Pfizer and Merck have entered this market segment among multinational corporations (MNCs), indicating potential for other early-stage PD-(L)1/VEGF bispecific antibodies to expand internationally as data matures [1]