KN026(HER2双抗)

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天风证券:维持石药集团“买入”评级 看好公司创新兑现长期价值
Zhi Tong Cai Jing· 2025-09-29 03:28
天风证券(601162)发布研报称,维持石药集团(01093)"买入"评级,预测公司2025-2027年营业收入分 别为283.98、301.45、322.42亿元,归母净利润为55.21、59.40、64.57亿元。公司发布2025年中期业绩。 公司实现收入132.73亿元,同比减少18.5%;实现净利润25.48亿元,同比减少15.6%。业绩下滑主要受集 采全面执行,成药业务收入压力较大影响。 天风证券主要观点如下: 成药业务产品销售承压,但授权收入大幅增长 2025H1,成药业务收入102.48亿元(包含授权收入10.75亿元),同比下滑24.4%。若扣除授权收入,产品 销售收入同比下滑32.3%。其中神经系统、抗肿瘤、抗感染、心血管等均有比较大的下滑,分别下滑 28.3%、60.8%、28.2%、29.3%。2025-2027多款创新药陆续申报上市,成药收入有望进入新增长曲线。 预计近3年提交上市的药物包括:SYS6010(EGFRADC)、KN026(HER2双抗)、多西他赛(白蛋白结合 型)、JSKN003(HER2ADC)、JMT101(EGFR单抗)、TG103(Fc-GLP1)等。 2025 ...
石药集团(01093):2025年上半年业绩承压,看好公司创新兑现长期价值
Tianfeng Securities· 2025-09-28 12:57
Investment Rating - The report maintains a "Buy" rating for the company [6][8]. Core Viewpoints - The company experienced a revenue decline of 18.5% year-on-year, with total revenue of 13.273 billion yuan and a net profit decrease of 15.6% to 2.548 billion yuan, primarily due to the impact of centralized procurement [1]. - The sales of traditional pharmaceutical products faced significant pressure, with a 24.4% decline in revenue to 10.248 billion yuan, and a 32.3% drop in product sales when excluding licensing income [2]. - The company is expected to enter a new growth phase with multiple innovative drugs set to be launched between 2025 and 2027, including SYS6010, KN026, and others [2]. - Licensing income has become a strong revenue and profit source, with a notable 120 million USD upfront payment for SYH2086 expected to contribute to future earnings [2]. - The company has initiated overseas clinical trials for SYS6010, which has received multiple regulatory recognitions, including Fast Track Designation from the FDA [3]. - The HER2 bispecific antibody KN026 has had its new drug application accepted by the Chinese National Medical Products Administration, showing promising clinical trial results [4]. Summary by Sections Financial Performance - For the first half of 2025, the company reported revenues of 13.273 billion yuan and a net profit of 2.548 billion yuan, reflecting a year-on-year decrease of 18.5% and 15.6%, respectively [1]. Traditional Pharmaceutical Business - The traditional pharmaceutical business generated 10.248 billion yuan in revenue, down 24.4% year-on-year, with a 32.3% decline in product sales when excluding licensing income [2]. Innovative Drug Pipeline - The company plans to submit multiple innovative drugs for approval from 2025 to 2027, including SYS6010 and KN026, which are expected to drive future revenue growth [2][4]. Licensing Income - Licensing income has significantly increased, with the company securing 6 business development deals and expecting continued contributions from these agreements [2]. Clinical Trials and Regulatory Approvals - SYS6010 has received Fast Track Designation from the FDA and Breakthrough Therapy Designation from NMPA, indicating strong regulatory support for its clinical development [3]. - The KN026 application is based on positive results from a pivotal clinical trial, demonstrating improved efficacy and safety compared to existing treatments [4]. Profit Forecast - The company is projected to achieve revenues of 28.398 billion yuan, 30.145 billion yuan, and 32.242 billion yuan, with net profits of 5.521 billion yuan, 5.940 billion yuan, and 6.457 billion yuan from 2025 to 2027 [6].