Core Viewpoint - The article discusses the rising popularity of fish oil in health circles, questioning whether it is a beneficial supplement or merely a "smart tax" with no real health benefits [1][2]. Summary by Sections What is Fish Oil? - Fish oil is derived from fish and is rich in omega-3 fatty acids, particularly EPA (Eicosapentaenoic Acid) and DHA (Docosahexaenoic Acid) [4]. - EPA is known for potentially lowering triglyceride levels, while DHA is crucial for the development of the nervous system and is significant for brain and eye health [4]. Can Fish Oil Prevent Heart Disease? - There is insufficient evidence to support the claim that fish oil can prevent heart disease [5]. - Initial beliefs stemmed from observations of Inuit populations consuming omega-3-rich diets, but further research indicated that genetic factors also play a role in their low heart disease rates [5]. - Numerous studies have produced inconsistent results regarding the effectiveness of fish oil in preventing cardiovascular diseases, with some suggesting it may even be harmful [6][7]. Health Benefits of Fish Oil - Current evidence suggests that fish oil can help regulate triglyceride levels, which is beneficial for patients with coronary heart disease and high triglyceride levels [9]. - DHA and EPA are beneficial for the neurological and visual development of infants [9]. Recommendations on Fish Oil Consumption - If individuals cannot consume 300-500 grams of fish or seafood weekly, fish oil supplements may be a convenient alternative [14]. - The best source of DHA and EPA remains whole foods, as they provide additional nutrients that may contribute to health benefits [14]. - The Chinese dietary guidelines recommend adults consume 120-200 grams of fish weekly, with increased intake for pregnant women [12][15]. Choosing Fish Oil Products - Consumers are advised to select reputable brands and differentiate between fish oil and cod liver oil, as they serve different purposes [16][17]. - It is important to check the concentration of EPA and DHA in fish oil products, as higher concentrations generally indicate better quality [18]. - Recommended daily intake for adults is around 200 mg of DHA, with pregnant women advised to consume 250 mg of DHA and EPA combined [19]. Conclusion - Fish oil should not be overhyped or completely dismissed; a balanced diet rich in omega-3 fatty acids from fish is ideal [21]. - For those unable to meet dietary recommendations, fish oil supplements can be considered, but consumers should be cautious and seek professional advice [21].

Core Insights - Altimmune, Inc. has appointed Linda M. Richardson as Chief Commercial Officer, effective September 16, 2025, bringing over 30 years of experience in sales, marketing, and business development across various therapeutic areas [1][2] - The appointment is seen as a strategic move as the company approaches the initiation of Phase 3 development of pemvidutide for Metabolic Dysfunction-Associated Steatohepatitis (MASH) [2] - Richardson believes pemvidutide has significant potential to improve patient outcomes in hepato-metabolic diseases and sees opportunities in Alcohol Use Disorder and Alcohol-associated Liver Disease [2] Company Overview - Altimmune is a late clinical-stage biopharmaceutical company focused on developing peptide-based therapeutics for liver and cardiometabolic diseases [5] - The lead product candidate, pemvidutide, is a GLP-1/glucagon dual receptor agonist targeting MASH, Alcohol Use Disorder, Alcohol-associated Liver Disease, and obesity [5] Inducement Grant Details - As part of her appointment, Richardson will receive options to purchase 278,000 shares and 96,000 restricted stock units (RSUs) [3][4] - The options will vest over four years, with one-fourth vesting on the one-year anniversary of the grant date [3][4]