CANADA - 2025/04/03: In this photo illustration, the Abbott Laboratories logo is seen displayed on a ... More smartphone screen. (Photo Illustration by Thomas Fuller/SOPA Images/LightRocket via Getty Images)SOPA Images/LightRocket via Getty Images Abbott Laboratories (NYSE:ABT) has greatly exceeded the broader S&P 500 index this year, with its stock price increasing by 18% compared to the S&P 500’s 6% rise. This strong performance is due to the company’s solid quarterly results and positive future forecasts ...

招商通知： 第三届全球手术机器人大会 # 研究背景 左心耳是心房颤动异位激动和左心房血栓的重要来源，隔绝左心耳有助于减少脑卒中发生和血栓形成。 Atricure 是全球最早进入该领域的公司， 2010 年首款产品 AtriClip 经 FDA 批准在美国上市，迄今在全 球植入超过 65 万例 ，是目前 全球应用最多的左心耳闭合器。 2023 年底， 美敦力 的 Penditure 经 FDA 批准在美国上市，是 全球第 2 款一端开口的左心耳闭合器械 。 领健医疗 的 V-Clip ® 是 全球第 3 款获批的一端开口的左心耳闭合器械 。 V-Clip ® 作为 我国首个、全球第 3 款 问世的 V 型单端开口闭合夹式系统 ，其突破性结构设计显著优化 了左心耳的捕获与闭合效果，有效攻克了传统封堵器械因形态匹配问题产生的残余渗漏难题。该系统兼容 心脏开胸手术及微创入路，实施左心耳夹闭后，可大幅削减源自心脏的卒中风险，并降低患者对抗凝药物 的长期需求 。 心未来 近日， 北京领健医疗科技有限公司 （简称" 领健医疗 "）自主研发的 国内首款V型左心耳闭合系统V- Clip ® 正式获得NMPA 批准上市（国械注准 ...

Core Viewpoint - Abbott Laboratories has received FDA approval for its Tendyne transcatheter mitral valve replacement system, enhancing its Structural Heart portfolio and providing a minimally invasive solution for patients with severe mitral annular calcification [1][5][6]. Company Summary - Abbott's stock increased by 1.3% to $132.94 following the announcement of the Tendyne system approval [2]. - The company has a market capitalization of $231.29 billion and an earnings yield of 3.9%, significantly higher than the industry average of 0.6% [4]. - Abbott's Structural Heart division includes a diverse product range, such as MitraClip and TriClip, which positions the company favorably in the market [3]. Product Importance - The Tendyne system addresses mitral valve diseases caused by severe mitral annular calcification, offering a less invasive alternative for high-risk patients who may not be suitable for open-heart surgery [5]. - The system's innovative design allows for adaptability to various patient anatomies, with a self-expanding valve that can be repositioned during implantation [6]. Industry Prospects - The transcatheter mitral valve replacement market is expected to grow at a compound annual growth rate of 20% from 2025 to 2030, driven by the rising prevalence of mitral valve diseases and a preference for minimally invasive procedures [8]. Stock Performance - Over the past year, Abbott's shares have increased by 32%, outperforming the industry growth of 10.3% [11].

报名：首届全球骨科大会 | 议程更新 报名：首届全球心血管大会 | 重磅亮点 合作伙伴征集：2025全球手术机器人大会 2025年4月16日，雅培公司（Abbott，纽约证券交易所代码：ABT）报告称，其第一季度的业绩超过了华尔街分析师对盈利的共识预期，但收入未达预期。 随后雅培的股价在早间交易中上涨了5%，达到每股132.53美元。标普500指数则略有下跌。 公布最新财报的同时，雅培宣布将在美国开展新的价值5亿美元（约合人民币36.5亿）的投资，研发制造用于筛查血液和血浆捐献的设备。 预计到2025年底 将投入使用。 # 财报亮点 数据概览 剔除汇率波动及新冠检测业务下滑影响后，雅培2025年一季度全球销售额为 103.6亿美元。 第一季度每股摊薄收益为 0.76美元 ；调整后的每股摊薄收益为1.09美元。 第一季度报告的销售额增长为 4.0% ；有机销售额增长为6.9%，若剔除与COVID-19检测相关的销售额，则增长率为8.3%。 报告的毛利率为销售额的 52.8% ；调整后的毛利率为57.1%。 报告营业利润率为销售额的 16.3% ；调整后的营业利润率为21.0%。 2025年全年指引 Abbott ...

Financial Data and Key Metrics Changes - The company achieved high single-digit sales growth of 7% in Q1 2025, with adjusted earnings per share (EPS) growing 11% to $1.09, finishing at the high end of the guidance range [12][29][27] - Excluding COVID testing sales, sales growth was over 8% [12] - Gross margin expanded by 140 basis points, and operating margin increased by 130 basis points compared to the prior year [27][30] Business Line Data and Key Metrics Changes - Nutrition sales increased by 7%, driven by high single-digit growth in adult nutrition and double-digit growth in US pediatric nutrition [14] - Diagnostics sales declined by 5%, primarily due to a decrease in COVID-19 testing sales; core laboratory diagnostics grew 6.5% excluding China [15][29] - Established a new system, Alinity N, for molecular nucleic acid testing, representing a billion-dollar market opportunity [17] - Medical devices sales grew 12.5%, with continuous glucose monitors achieving over 20% growth [19] Market Data and Key Metrics Changes - Sales in the EPD segment increased by 8%, with double-digit growth in more than half of the key 15 markets [18] - The US dollar's weakening had a favorable impact on sales compared to exchange rates at the time of the previous earnings call [29] Company Strategy and Development Direction - The company is focused on navigating the complexities of a dynamic economic environment, including the impact of new tariff policies [10][11] - A diversified business model is emphasized as a strength, allowing the company to manage global challenges effectively [10] - The company plans to launch over 25 key new products over the next three years, contributing to sustained growth [27] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in maintaining guidance despite tariff impacts, estimating a few hundred million dollars in tariff-related costs for 2025 [45][46] - The company is actively assessing various scenarios to mitigate tariff impacts and is optimistic about its manufacturing network's flexibility [50][52] - Management expects the second half of 2025 to outperform the first half due to new product launches and improved market conditions [102] Other Important Information - The company is investing in R&D and expanding its portfolio in biosimilars and diagnostics, with a focus on enhancing its competitive position [18][90] - The company is also exploring M&A opportunities in medical devices and diagnostics while maintaining a disciplined approach to capital allocation [94][96] Q&A Session Summary Question: Impact of tariffs on full-year guidance - Management confirmed that tariffs will have a financial impact, estimating a few hundred million dollars for 2025, with a focus on mitigating strategies [45][46] Question: State of the EP franchise and Volt approval timeline - Management expressed optimism about the EP franchise, highlighting strong initial feedback for Volt and a potential US approval timeline in early 2026 [65][66] Question: Broader diagnostic strategy and M&A considerations - Management acknowledged challenges in the diagnostics segment, particularly in China, and emphasized the importance of M&A to enhance growth [82][90] Question: Acceleration of top-line growth in the second half - Management indicated that new product launches and favorable comparisons to previous year performance will drive growth acceleration [102][106] Question: Gross margin expectations amid tariff impacts - Management confirmed that tariffs would primarily affect gross margins, but favorable FX movements could help offset some impacts [108] Question: Plans for seeking exemptions from tariffs - Management stated that while they are engaged with industry associations, they do not rely on hope for tariff exemptions and are focused on data-driven strategies [130][132] Question: Diversified model and potential for unlocking value - Management reiterated the value of their diversified model and stated that they are continuously evaluating opportunities to create value without current plans for divestitures [138][140]

Core Insights - Abbott's TriClip transcatheter edge-to-edge repair system shows significant and sustained improvements in treating tricuspid regurgitation (TR) after two years, reducing hospitalizations due to heart failure compared to medical therapy [1][6][7] - The TRILUMINATE Pivotal trial highlights the device's effectiveness in improving patients' quality of life and reducing the severity of TR [4][5][6] Group 1: Trial Results - The TRILUMINATE Pivotal trial demonstrated that after two years, TriClip therapy significantly reduced heart failure hospitalizations (HFH) compared to the control group, with rates of 0.19 vs. 0.26 events per patient-year [7] - 84% of patients treated with TriClip achieved a reduction in TR to moderate or less (grade ≤ 2), compared to only 21% in the control group [7] - Patients receiving TriClip experienced an average improvement of over 15 points in the Kansas City Cardiomyopathy Questionnaire (KCCQ) score, indicating enhanced quality of life [7] Group 2: Patient Impact - TriClip offers a viable treatment option for patients with severe TR who are not suitable candidates for surgery, improving their quality of life and reducing hospitalization risks [2][5] - The trial results reinforce the importance of TriClip in managing TR, allowing patients to reclaim their lives while minimizing the risk of heart failure [5][6] Group 3: Study Details - The TRILUMINATE Pivotal trial is the first randomized, controlled study comparing the safety and effectiveness of the TriClip system against medical therapy alone for severe TR [8] - The primary endpoint of the trial included all-cause mortality, tricuspid valve surgery, heart failure hospitalizations, and quality-of-life improvement as measured by the KCCQ score [8]

合作伙伴征集：2025全球手术机器人大会 报名：首届全球眼科大会 | 暂定议程 报名：首届全球心血管大会 | 奖项报名 报名：首届全球骨科大会 | 奖项报名 心未来 近日， Laplace Interventional 宣布完成了 2200万美元 （约合 人民币1.6亿 ）的 C轮 融资 ，以支持 Laplace TTVR系统 的开发。 # 高管评价 Laplace Interventional 的创始人兼首席执行官 Ramji Iyer 表示："本轮融资对公司而言是一个重要的里程碑，进一步验证了我们过去几年取得的进展。我们感谢患 者、医生以及新老投资者的持续支持，期待尽快启动关键性试验。" Aphelion Capital 的 Ned Scheetz 表示："Aphelion Cardeation 是一家风险基金，旨在投资与美国心脏协会使命相一致的创新医疗保健产品、服务和技术，它很自豪能 够参与本轮融资。Laplace TTVR系统及其改变全球数百万患者护理的潜力让我们深受启发。" # 关于Laplace TTVR系统 Laplace TTVR系统是一种用于治疗 严重或症状明显的三尖瓣反流 的新型微创手术技 ...