Core Viewpoint - The article emphasizes the significance of spatial omics and mass spectrometry imaging (MSI) technology in clinical diagnostics and precision medicine, highlighting its potential for future research and applications [2][3]. Group 1: Spatial Omics and MSI Technology - In 2022, Nature recognized spatial omics as one of the seven most promising technologies, showcasing its potential in life sciences [3]. - MSI technology offers remarkable multi-scale visualization capabilities, enabling molecular spatial localization and qualitative analysis from whole organisms to single cells [3]. - This technology reveals the specific distribution of molecules within biological systems and provides critical information on the relationship between molecular function and spatial location, aiding in the understanding of biochemical processes and the roles of molecules in physiological and pathological mechanisms [3]. Group 2: Future Prospects of MSI Technology - The future of MSI technology appears promising, with a focus on high-throughput detection and precise identification at the single-cell level [4]. - MSI is expected to evolve into a new generation of molecular pathology diagnostic technology, contributing to the advancement of precision medicine through interdisciplinary and multi-technology integration [4]. - The integration of artificial intelligence (AI) with MSI is anticipated to enhance ion recognition and analysis efficiency, facilitating the development of new principles in mass spectrometry [4]. Group 3: Upcoming Events and Contributions - Professor Repaal Abulizi will present at the 18th China Scientific Instrument Development Annual Conference (ACCSI 2025) in Shanghai, sharing insights on MSI technology [4]. - The conference aims to promote healthy and rapid development in the scientific instrument industry, providing a platform for effective communication among various stakeholders [11].

Core Viewpoint - The Chongqing Meteorological Information and Technology Support Center has announced procurement intentions for 14 types of meteorological instruments and equipment, with a total budget of 102 million yuan, expected to be procured between March and July 2025 [1][2][3]. Summary by Categories Procurement Overview - The procurement includes various instruments such as visibility measurement instruments, frozen soil measurement instruments, intelligent weather phenomenon observation instruments, acid rain observation instruments, and flux observation instruments [3][5]. Specific Projects and Budgets - The projects include: - "Tiangong" data support platform expansion with a budget of 23.7 million yuan, aimed at enhancing data service capabilities [5]. - Meteorological observation system upgrades, including the procurement of precision dew point meters and wind tunnels, with a budget of 4.99 million yuan [5]. - Construction of 4 flux observation systems in Chongqing with a budget of 11.2 million yuan [5]. - Establishment of a vegetation and phenology observation system in Fuling, Chongqing, with a budget of 800,000 yuan [5]. - Development of 13 sets of all-flash detection equipment in Chongqing with a budget of 2.99 million yuan [6]. Technological Enhancements - The procurement aims to enhance capabilities in data processing, storage management, and monitoring, as well as improve the safety and stability of meteorological operations through upgraded communication systems [5][6].

特别提示 微信公众号机制调整，请点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我们的推送。 仪粉e r们，今天是高薪精品仪器职位专辑，有不少 新的雇主 哦！ 销售精英，热招职位 Ho t r e c r u itme n t p o siti o n s 安捷伦科技（中国）有限公司 Ch a n n e l Sa l e s 病理业务 IVD 广州- 2 0 k - 3 0 k · 1 3薪 岗位要求： （分析化学、化学、化工、制药、仪器设备、电子电路、环境工程、食品科学等相关专业）或仪器等 本科及以上学历，学习能力 强。 常州磐诺仪器有限公司 色相气质销售 重庆- 8 k - 1 2 k · 1 3薪 岗位要求： 具有一定理工科背景（分析化学、化工、检验检疫、仪器设备、电子电路、环境工程、食品科学等相关专业优先）；具有良好的语 言表达、沟通及组织及协调能力。 天美仪拓 实验室产品销售 杭州- 8 k - 1 0 k · 1 3薪 岗位要求： 大专及以上学历，生物、医药或生命科学相关专业，3年以上市场销售相关工作经验；出色的谈判技巧和沟通能力。 岛津（上海）实验器材有限公司 ...

Core Viewpoint - The integration of AI into scientific instruments is transforming them from precise tools into intelligent entities, driving a revolution in productivity and innovation across various sectors [2][4]. Group 1: AI's Impact on Scientific Instruments - AI is enhancing the capabilities of scientific instruments, enabling features such as automatic parameter calibration in spectrometers and real-time ecological data analysis in environmental monitoring [3][4]. - The application of AI allows for smarter decision-making and optimization in scientific research, manufacturing processes, and data analysis, significantly reducing trial-and-error costs [3][4]. Group 2: Upcoming Forum Details - The "ACCSI 2025 Artificial Intelligence and Scientific Instruments Integration Development Forum" will take place in Shanghai on May 12-13, 2025, focusing on AI-driven innovations in scientific instruments [4][20]. - The forum will feature discussions on AI's role in advancing spectrometry and chromatography, with participation from over 20 leading experts from various sectors [4][5]. Group 3: Expert Contributions - Notable speakers include Professor Ouyang Wanli from Shanghai AI Laboratory, who will discuss the new ecosystem of high-end instrument development empowered by AI [4][8]. - Other experts will cover topics such as AI in environmental instrument development, non-invasive blood glucose detection, and the integration of AI in food safety monitoring [7][10]. Group 4: Industry Transformation - AI is not just a tool for efficiency but a catalyst for interdisciplinary innovation, reshaping how scientific instruments are developed and utilized across different fields [4][5]. - The forum aims to explore how traditional instrument companies can build new competitive advantages through AI integration in manufacturing and operational processes [5][6].

近日，合肥工业大学发布7项仪器设备采购意向，预算总额达1.69亿元，涉及晶圆缺陷检测自动对焦平台、晶圆形貌自 动测量运动平台、高精度气浮旋转轴系、5轴运动检测平台、光纤双频激光干涉仪、高精度五轴气浮运动平台、全场非 接触扫描三维振动测试系统等，预计采购时间为2025年4~6月。 合肥工业大学2025年4~6月仪器设备采购意向汇总表 | 采购 | 需求概况 | 预算 | 采购 | | --- | --- | --- | --- | | 项目 | | 万元 | 时间 | | | 采购国产设备，包括晶圆缺陷检测自动对焦平台、晶圆形 | | | | 精密测量 | 貌自动测量运动平台、高精度气浮旋转轴系、5轴运动检 | | 2025 | | 仪器原理 | 测平台、光纤双频激光干涉仪、高精度五轴气浮运动平 | 1507 | 年4月 | | 验证平台 | 台、全场非接触扫描三维振动测试系统、多自由度微纳位 | | | | | 移驱动传感测试标定系统等。 | | | | | 采购进口设备，包括超高精度坐标测量仪、可自动跟踪反 | | | | 跨尺度精 | 射镜的激光干涉仪、多束激光干涉仪、机器人性能测量及 | | 2025 ...

导读： 近日，武汉大学发布多批政府采购意向，仪器信息网特对其中的仪器设备品目进行梳理，统计出3项仪器设备采购意向，预算 总额达1.99亿元。 特别提示 微信公众号机制调整，请点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我们的推送。 近日，武汉大学发布3项仪器设备采购意向，预算总额达1 . 9 9亿元，涉及超低温固体高通量测试系统、多功能物质结构 表征测试平台、原位谱学探测系统、微观物种收集分析系统、荷端物相检测高分辨液相色谱质谱联用仪、荷端物相检测 电化学质谱联用仪、光源感知探测运用系统等，预计采购时间为2 0 2 5年4月。 武汉大学2 0 2 5年4月仪器设备采购意向汇总表 | 采购 | | 预算 | 采购 | | --- | --- | --- | --- | | | 需求概况 | | | | 项目 | | 万元 | 时间 | | 水风光清 | （一）采购标的名称：水风光清洁能源互补运行与控制模 | 8472 | 2025年 | | 洁能源互 | 拟交叉集成创新支撑中心项目四期 （二）采购标的需实现 | | 4月 | | 补运行与 | 的主要功能或目标：项目面向国家大 ...

Core Viewpoint - The ACCSI 2025 8th Inspection and Testing Industry Summit highlights the integration of digital economy and food safety, emphasizing that digital capabilities are essential for building quality barriers in enterprises [3][8]. Group 1: Summit Overview - The summit will take place on May 13 at the Shanghai Fuyue Hotel, focusing on the deep integration of artificial intelligence and big data with food testing and quality control [5]. - Key industry experts and representatives from leading companies will discuss core topics such as food authenticity testing, laboratory digitization, and dairy quality management [5][7]. Group 2: Industry Participation - Major dairy companies such as Yili, Bright Dairy, and Mengniu will participate, marking a new phase of ecological collaboration in China's food testing industry [7]. - Mengniu's Technical Director will present on the integration of laboratory digitization and production collaboration, sharing experiences on optimizing testing processes through AI technology [7]. Group 3: Industry Signals and Future Outlook - The summit serves as a platform for technical exchange and signals a clear industry trend: digital capabilities are becoming a core element for enterprises to establish quality barriers [8]. - Experts believe that through a three-dimensional breakthrough of "technology + management + ecology," the food testing industry can take a more proactive role in global quality safety governance [8]. - The event will also focus on aligning domestic standards with international rules to enhance the competitiveness of China's food testing industry [8].

导读： 近日，诺华核药Pluvicto新适应症上市申请获CDE受理，这是该药在中国申报的第二个适应症，2024 年， Pluvicto 销售额达 13.9亿美元，是首个年销售 额破10亿美元的核药。 特别提示 微信机制调整，点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我们的推送。 近日， 诺华核药Pluv i c t o新适应症上市申请获CDE受理 ，这是该药在中国申报的第二个适应症，此次新适应症若获批，将进一步扩大其覆盖 人群，把治疗线数前移至化疗前阶段。 | 序号 | 受理号 | 药品名称 | 药品类型 | 申请类型 | 注册分类 | 企业名称 | 承力日期 | | --- | --- | --- | --- | --- | --- | --- | --- | | | JXHS2500054 | 撸[177Lu] 特昔维匹肽 | 化药 | 进口 | | Novartis Pharma AG;Advanced Accelerator | 2025-04-28 | | | | | | | | Schweiz | | | | | 注射液 | | | 5.1 | | | | | ...

Core Viewpoint - The Chinese non-destructive testing (NDT) industry is experiencing significant growth and technological advancement, with domestic companies like Yirui Technology and Rilian Technology leading the way in innovation and market performance [2][9]. Group 1: Domestic Companies' Performance - Yirui Technology invested over 300 million yuan in R&D, achieving international leadership in photon counting detector technology, breaking a 20-year monopoly in medical CT detectors by Western companies [2]. - SanYing Precision reported a 91% increase in net profit, with its self-developed nanoVoxel series micro-CT achieving a resolution of 0.5 microns, effectively replacing imported equipment for major clients and saving over 40% in procurement costs [3]. - Rilian Technology's revenue and net profit both increased by 25%, successfully producing an 180 kV micro-focus X-ray source and enhancing defect detection accuracy to 99.5% with its AI detection system, significantly improving battery inspection efficiency for CATL [4]. Group 2: Technological Innovations - Steel Research Nake's phased array detection system was successfully applied in Baowu Steel's production line, achieving an international-leading automatic detection speed of 200 rods per hour [5]. - Ultrasonic Electronics achieved revenue and profit growth, breaking through 3D full-focus technology, with its wind turbine blade detection system applied to the world's largest 16MW offshore wind turbine, improving detection accuracy by 60% compared to traditional methods [6]. - Duopule developed a liquid-cooled plate water immersion detection system that addresses welding quality issues in electric vehicle batteries, receiving bulk orders from BYD and CATL [7]. - Zhongke Intelligent's self-developed electromagnetic ultrasonic corrosion detection instrument replaced Canadian products in the West-East Gas Pipeline project, achieving 100% localization [8]. Group 3: Market Overview - The NDT service market in China has exceeded 3 trillion yuan, with annual instrument sales surpassing 20 billion yuan. The demand for NDT technology is surging across various sectors, including new energy, semiconductors, aerospace, rail transportation, and life sciences [9]. - Domestic equipment manufacturers are breaking foreign monopolies through technological innovation, becoming the backbone of industry development [9]. Group 4: Upcoming Forum - The "ACCSI 2025 Second Non-Destructive Testing Technology Innovation Development Forum" will be held on May 13, 2025, in Shanghai, gathering top talents from industry, academia, and research to discuss the latest technological advancements and industrial applications [10]. - The forum will feature authoritative reports and discussions on cutting-edge technologies, including X-ray spectroscopy imaging and terahertz imaging technology, providing a platform for deep communication and collaboration [12][13].

Core Viewpoint - Microplastics and nanoplastics (MNPs) have emerged as significant environmental pollutants, raising concerns regarding their impact on ecological health and public well-being due to their microscopic size, widespread distribution, and resistance to degradation [2][3]. Group 1: Presence and Entry Pathways - Microplastics are found in various natural environments, including water sources, soil, air, and even within biological organisms [3]. - They can enter the human body through multiple pathways, such as the food chain, drinking water, air inhalation, and skin contact, making them a pervasive form of pollution [3][4]. Group 2: Toxicological Effects - Current research indicates that microplastics pose potential health risks, affecting multiple biological systems, including the nervous, urinary, and reproductive systems [6]. - Microplastics can induce oxidative stress, activate inflammatory responses, disrupt apoptosis and autophagy balance, and alter gene expression, leading to chronic inflammation, tissue damage, and metabolic disorders [6][17][18]. Group 3: Specific Systemic Impacts - **Nervous System**: Microplastics can cross the blood-brain barrier and accumulate in the brain, with concentrations significantly higher than in the liver and kidneys. This accumulation is linked to neurodegenerative diseases, such as Alzheimer's, potentially accelerating cognitive decline [8]. - **Urinary System**: Microplastics can accumulate in the kidneys, impairing their physiological functions and leading to chronic kidney diseases. They induce oxidative stress and activate inflammatory pathways, contributing to long-term health risks [10][11]. - **Reproductive System**: Exposure to polystyrene nanoparticles (PS-NP) during pregnancy has been shown to reduce testosterone levels and sperm quality in male offspring, indicating reproductive toxicity [13][14]. Group 4: Cellular Function Impact - Microplastics significantly affect cellular vitality, with studies showing that polystyrene nanoparticles can induce oxidative stress and apoptosis in both cancerous and normal cells, highlighting their specific toxicity [16][17]. Group 5: Future Research Directions - There is a pressing need to assess the long-term health impacts of microplastics due to their persistence in the environment and accumulation in biological systems. Establishing long-term tracking cohorts and health monitoring systems is essential for understanding the relationship between microplastic exposure and various diseases [20]. - Research should also focus on the synergistic effects of microplastics with other environmental pollutants, such as heavy metals and persistent organic pollutants, to understand their combined toxicological impacts [21].