证券代码：920009 证券简称：丹娜生物 公告编号：2025-126 二、募集资金监管协议的签署情况 为规范公司募集资金管理，保护投资者权益，根据《北京证券交易所股票上 市规则》和《北京证券交易所上市公司持续监管指引第 9 号——募集资金管理》 以及公司《募集资金管理制度》相关要求，公司开设募集资金专项账户存放本次 向不特定合格投资者发行股票的募集资金，并已分别与存放募集资金的商业银行 （乙方）和招商证券股份有限公司（丙方）签订《募集资金三方监管协议》（以 下简称"三方监管协议"）。 1/3 丹娜（天津）生物科技股份有限公司 关于签署募集资金三方监管协议的公告 本公司及董事会全体成员保证公告内容的真实、准确和完整，没有虚假 记载、误导性陈述或者重大遗漏，并对其内容的真实性、准确性和完整性承 担个别及连带法律责任。 一、募集资金情况概述 丹娜（天津）生物科技股份有限公司（以下简称"公司"）向不特定合格投 资者公开发行股票并在北京证券交易所上市申请于 2024 年 12 月 27 日经北京证 券交易所上市委员会审核同意，并于 2025 年 9 月 13 日获得中国证券监督管理委 员会（以下简称"中国证监会"）出 ...

Summary of Key Points Core Viewpoint The Beijing Stock Exchange (BSE) has seen a decrease in trading volume and value over the past week, with a total of 282 listed companies as of November 9, 2025. The market is also witnessing new listings and ongoing IPO activities, indicating a dynamic but challenging environment for investors. Trading Activity - As of November 9, 2025, the BSE has 282 listed companies with a total share capital of 39.225 billion shares and a circulating share capital of 25.056 billion shares [2] - For the week of November 3 to November 9, the trading volume was 4.925 billion shares, a decrease of 17.24% week-on-week, while the trading value was 1136.16 billion yuan, down 21.40% from the previous week [3] - The average trading price during this period was 23.07 yuan, reflecting a decrease of 5.03% [3] - The BSE 50 Index fell by 3.79% to 1522.73 points, with 9 stocks rising and 41 stocks declining [3] New Listings and IPOs - Two companies successfully listed on the BSE during the week of November 3 to November 9, 2025 [7] - The newly listed companies include: - **Danna (Tianjin) Biotechnology Co., Ltd.**: Listed on November 3, 2025, with a first-day trading surge of 497.08% and a closing price of 102.10 yuan [8][10] - **Zhongcheng Consulting Group Co., Ltd.**: Listed on November 7, 2025, with a first-day increase of 170.08% and a closing price of 35.60 yuan [13][30] - Both companies aim to raise approximately 1.37 billion yuan for various projects, including R&D and infrastructure [10][30] Financial Performance of Newly Listed Companies - **Danna Biotechnology**: - Revenue for 2022-2024: 295 million yuan, 237 million yuan, 240 million yuan; Net profit: 44.62 million yuan, 77.60 million yuan, 87.19 million yuan [10] - 2025 H1 revenue decreased by 1.38% to 116 million yuan, while net profit increased by 29.55% to 49.96 million yuan [11] - **Zhongcheng Consulting**: - Revenue for 2022-2024: 303 million yuan, 368 million yuan, 396 million yuan; Net profit: 64.36 million yuan, 81.06 million yuan, 105 million yuan [13] - 2025 H1 revenue decreased by 4.08% to 191 million yuan, and net profit decreased by 2.66% to 53.29 million yuan [14] Ongoing IPO Activities - As of November 9, 2025, there are 104 companies awaiting approval for listing on the BSE, with various stages of the IPO process [6] - Two companies submitted registration during the week, while three companies passed the listing committee meetings [25][26] - Notable companies that passed the listing committee include: - **Qilong Ocean**: Engaged in oil drilling equipment manufacturing, aiming to raise 382 million yuan [27] - **Haiseng Medical**: Focused on medical device manufacturing, seeking to raise 370 million yuan [30] - **Guoliang New Materials**: Specializing in refractory materials, aiming to raise 175 million yuan [33] Market Dynamics - The BSE is experiencing fluctuations in trading activity and new listings, reflecting both opportunities and challenges in the current market environment [3][6][25]

Market Overview - The medical device sector experienced a slight decline of 0.13% on November 11, with Danaher Biomedical leading the drop [1] - The Shanghai Composite Index closed at 4002.76, down 0.39%, while the Shenzhen Component Index closed at 13289.0, down 1.03% [1] Top Performers - Anxu Bio (688075) saw a closing price of 42.54, with an increase of 4.39% and a trading volume of 23,700 [1] - Nanwei Medical (688029) closed at 86.17, up 3.89% with a trading volume of 31,700 [1] - Yirui Technology (688301) closed at 109.90, increasing by 2.65% with a trading volume of 22,000 [1] Underperformers - Danaher Biomedical (920009) closed at 77.69, down 4.91% with a trading volume of 16,300 [2] - Ruimait (301367) closed at 86.41, down 4.32% with a trading volume of 18,600 [2] - Tianchen Medical (688013) closed at 52.68, down 3.59% with a trading volume of 26,900 [2] Capital Flow - The medical device sector saw a net outflow of 642 million yuan from institutional investors, while retail investors contributed a net inflow of 463 million yuan [2][3] - The top net inflows from retail investors were observed in Nanwei Medical (688029) with 46.22 million yuan, and Tianchen Medical (688013) with 24.78 million yuan [3]

IPO Pipeline Status - As of November 9, there are 276 companies in the IPO pipeline, including 21 on the Shanghai Main Board, 35 on the Sci-Tech Innovation Board, 21 on the Shenzhen Main Board, 26 on the ChiNext, and 173 on the Beijing Stock Exchange [1] Newly Listed Companies - From November 3 to November 9, five companies were newly listed: - Dana (Tianjin) Biotechnology Co., Ltd. on the Beijing Stock Exchange with a closing price of 102.10 CNY per share, a rise of 497.08%, and a trading volume of 6.65 billion CNY [3] - Suzhou Fengbei Biotechnology Co., Ltd. on the Shanghai Main Board with a closing price of 66.76 CNY per share, a rise of 172.60%, and a trading volume of 16.50 billion CNY [3] - Daming Electronics Co., Ltd. on the Shanghai Main Board with a closing price of 64.45 CNY per share, a rise of 413.55%, and a trading volume of 16.94 billion CNY [4] - Delijia Transmission Technology (Jiangsu) Co., Ltd. on the Shanghai Main Board with a closing price of 70.52 CNY per share, a rise of 51.07%, and a trading volume of 18.50 billion CNY [5] - Zhongcheng Zhixin Engineering Consulting Group Co., Ltd. on the Beijing Stock Exchange with a closing price of 38.54 CNY per share, a rise of 170.08%, and a trading volume of 4.62 billion CNY [6] New Counseling Record Companies - During the same period, 10 companies were added to the counseling record, including: - Hangzhong Tianqi (Chongqing) Microelectronics Co., Ltd., focusing on communication and intelligent terminal chips [7] - Anwen Technology Group Co., Ltd., specializing in automotive cabin safety and comfort components [9] - Duality Biotherapeutics, Inc., a clinical-stage innovative biopharmaceutical company [9] - Wuhan Jiachen Electronics Technology Co., Ltd., engaged in high-voltage safety systems for new energy vehicles [9] - Guangdong Jingyi Furniture Co., Ltd., focusing on office seating solutions [9] - Inner Mongolia Dongyuan Environmental Protection Technology Co., Ltd., involved in wastewater treatment [9] - Ningbo Jinlai Chemical Co., Ltd., a chemical product manufacturer [9] - Shenzhen Zhongji Automation Co., Ltd., specializing in lithium battery automation production equipment [10] - Huanuo Star Technology Co., Ltd., engaged in radar and intelligent robotics research [10] - Anhui Xinyuan Technology Co., Ltd., focusing on fine chemicals [10] Companies Approved for Review - Five companies successfully passed the review process from November 3 to November 9: - Shandong Qilong Marine Oil Steel Pipe Co., Ltd., involved in marine drilling riser development [12] - Chongqing Zhixin Industrial Co., Ltd., specializing in automotive welding parts [12] - Shaanxi Tourism Culture Industry Co., Ltd., offering tourism-related services [12] - Zhejiang Haiseng Medical Devices Co., Ltd., providing anesthesia and monitoring medical devices [12] - Hebei Guoliang New Materials Co., Ltd., focusing on high-temperature industrial refractory materials [12] Companies Registered Successfully - Two companies received registration approval during the period: - Ningbo Jianxin Superconducting Technology Co., Ltd., involved in MRI equipment core components [15] - Inner Mongolia Shuangxin Environmental Protection Materials Co., Ltd., focusing on PVA and specialty fibers [15] Companies Terminated IPO Review - Two companies withdrew their IPO applications: - Fujian Haichuang Optoelectronic Technology Co., Ltd., specializing in laser technology [16] - Shandong Canon Technology Co., Ltd., focusing on energy-saving and environmental protection technologies [17]

Group 1: New Stock Performance - Last week (November 3-7), 5 new stocks were listed with an average first-day price increase of 260.87%[3] - Four stocks had first-day gains exceeding 100%, including Danna Biotech at 497.08%[3] - No new stocks experienced a first-day decline below their issue price[3] Group 2: Weekly New Stock Issuance Trends - The total amount raised from new stock offerings last week was 35.85 billion yuan, a decrease of 55.82 billion yuan compared to the previous week[4] - The number of new stocks listed last week was 5, compared to 4 the week before[5] - The average first-day price increase for new stocks last week was 260.87%, up from 168.79% the previous week[5] Group 3: Monthly New Stock Trends - In the first week of November, 5 new stocks were listed, raising 35.85 billion yuan with 0% first-day decline rate[12] - In October, 9 new stocks raised 128.21 billion yuan, with an average first-day increase of 244.64%[12] - The average first-day price increase for new stocks in September was 258.52%[12] Group 4: Upcoming New Stock Subscriptions - This week, there are 2 new stocks available for online subscription, one from the main board and one from the North Exchange[20] - Hai'an Group is expected to raise 31.07 billion yuan, while Nant Technology is expected to raise 3.22 billion yuan[20] - The subscription dates are November 14 for Hai'an Group and November 11 for Nant Technology[20] Group 5: Risk Considerations - New stock performance is influenced by market sentiment, which can affect issuance outcomes[21] - If post-issuance performance does not meet expectations, it may impact future market performance of new stocks[21] - Newly listed stocks often have lower liquidity, leading to potential price volatility[21]

Macro Strategy - In October, China's exports showed a year-on-year decline of -1.10%, marking the first negative growth since March 2025, which affected the cumulative year-on-year growth rate, decreasing from 6.10% in September to 5.30% in October. This decline is attributed to a high base in October 2024 and a temporary escalation in trade conflicts between China and the US in early October 2025 [3][4]. Market Overview - From November 3 to November 7, 2025, A-share indices experienced wide fluctuations, with the Shanghai Composite Index rising by 1.08% and the ChiNext Index increasing by 0.65%. The market is expected to continue a "slow bull" trend with wide fluctuations in November due to reduced short-term trade conflict risks between China and the US [4][5]. - Among the 31 first-level industries, the top performers were electric equipment and coal, with weekly increases of 4.98% and 4.52%, respectively. Conversely, the beauty care and computer sectors saw declines of -3.10% and -2.54% [6][7]. North Exchange Market - As of November 7, 2025, the North Exchange had 282 listed stocks, with an average total market value of 908.24 billion yuan, reflecting a 1.24% increase from the previous week. The liquidity decreased, with average trading volume dropping by 17.23% [11][12]. - The highest weekly gain was recorded by Danna Biological, which surged by 377.78% in its first week of trading, while the largest decline was seen in Beiyikang, which fell by 12.35% [13]. Vaccine Industry - The vaccine industry is experiencing structural differentiation, with companies like Kangtai Biological and Zhonghui Biological making significant advancements in vaccine development for specific populations, such as infants and pregnant women. The updated technical guidelines emphasize the importance of vaccination for high-risk groups [17][21]. - The vaccine sector's performance remains under pressure, with a year-to-date decline of -1.57%. The industry is focusing on innovation and international expansion to navigate current challenges [19][21]. - The vaccine sector's price-to-earnings ratio (PE) is currently at 99.07X, reflecting a decrease of 4.97X from the previous week, while the price-to-book ratio (PB) remains stable at 1.94X [20]. Investment Recommendations - The vaccine industry is advised to focus on innovation and international markets, as the current market conditions present challenges due to supply-demand imbalances and intense competition. Companies with strong technological capabilities and differentiated product lines are recommended for investment [21][23].

Group 1 - The North Exchange 50 index decreased by 3.79%, but trading volume remained above 20 billion, showing an increase from the previous 17 billion [8][19] - The market adjustment was a natural pullback after a previous policy-driven surge, with a focus on sectors like electricity, chemicals, photovoltaics, lithium batteries, and energy storage, which performed well [8][9] - The themes of anti-involution and price increases are spreading, aligning with market demands for "high cuts and low" [9][10] Group 2 - The North Exchange's PE (TTM) average is 89.33 times, with a median of 44.73 times, indicating a decrease in valuation [22][30] - The trading volume for the week was 4.922 billion shares, a decrease of 17.23% from the previous week, while the trading amount was 113.591 billion yuan, down 21.37% [26][19] - The margin financing balance increased to 7.951 billion yuan, up by 0.47 billion yuan from the previous week [28][19] Group 3 - Two new stocks were listed this week: Danna Biological and Zhongcheng Consulting, with significant first-day price increases of 497.08% and 170.08% respectively [32][33] - As of November 7, 2025, there are 282 companies listed on the North Exchange [32] - Next week, one company (Nante Technology) is scheduled for subscription, and two companies (Tongbao Optoelectronics, Agricultural University Technology) are set for review [37] Group 4 - Among the North Exchange stocks, 52 increased while 229 decreased, resulting in a rise-fall ratio of 0.23 [40] - The top gainers included Caneng Electric (+31.13%) and Anda Technology (+20.38%) [41][40] - The top five stocks by turnover rate were Caneng Electric, Jinhua New Materials, and Deer Chemical, indicating high trading activity [46]

Core Viewpoint - Danah Biotechnology (920009) experienced a decline of 2.16% in its stock price, with a trading volume turnover rate of 21.20% and a total transaction value of 1.25 billion yuan on the day of reporting [2] Trading Activity Summary - The stock was listed on the exchange due to its turnover rate reaching 21.20%, with institutional investors net selling 158,900 yuan [2] - The top five trading departments accounted for a total transaction value of 39.72 million yuan, with a buying transaction value of 21.99 million yuan and a selling transaction value of 17.73 million yuan, resulting in a net buying of 4.25 million yuan [2] - Among the trading departments, one institutional specialized seat was present, with a buying amount of 2.23 million yuan and a selling amount of 2.39 million yuan, leading to a net sell of 158,900 yuan [2] Detailed Trading Department Activity - The top buying departments included: - Dongfang Caifu Securities, with a buying amount of 6.24 million yuan and a selling amount of 0.22 million yuan - Guotou Securities, with a buying amount of 5.24 million yuan and no selling [2] - The top selling departments included: - Guojin Securities, with a selling amount of 6.15 million yuan and a buying amount of 0.15 million yuan - Guotou Securities, with a selling amount of 3.45 million yuan and a buying amount of 0.0008 million yuan [2]

Core Viewpoint - Dana Biological (920009) experienced significant trading activity on November 7, 2025, with a turnover rate of 21.20% and a transaction volume of 1.5265 million shares, amounting to 1.25 billion yuan [1][2]. Trading Activity Summary - The stock reached a turnover rate of 21.20% on the trading day [1]. - Total transaction volume was 1.5265 million shares, with a total transaction value of 1.25 billion yuan [1]. - The top buying seat was from Dongfang Caifu Securities, which purchased approximately 6.238 million yuan worth of shares [2]. - The top selling seat was from Guojin Securities, which sold approximately 6.150 million yuan worth of shares [2]. Detailed Trading Data - Buying and selling activities were recorded from various securities firms, with notable transactions including: - Dongfang Caifu Securities: Buy 6,238,064.33 yuan, Sell 215,498.42 yuan [2]. - Guojin Securities: Buy 1,472,445.97 yuan, Sell 6,150,367.76 yuan [2]. - Other significant buying and selling activities were noted from institutions and other securities firms [2].

Market Overview - On November 6, the Shanghai Composite Index rose by 0.97%, with the total margin balance reaching 24,988.49 billion yuan, an increase of 7.371 billion yuan compared to the previous trading day [1] - The margin balance in the Shanghai market was 12,736.82 billion yuan, up by 6.533 billion yuan, while the Shenzhen market's margin balance was 12,172.10 billion yuan, increasing by 0.856 billion yuan [1] Industry Analysis - Among the industries tracked by Shenwan, 15 sectors saw an increase in margin balances, with the electronics sector leading with an increase of 4.468 billion yuan, followed by the power equipment and non-ferrous metals sectors, which increased by 2.510 billion yuan and 0.737 billion yuan, respectively [1] Stock Performance - A total of 1,764 stocks experienced an increase in margin balances, accounting for 47.15% of the market, with 301 stocks seeing an increase of over 5% [1] - Tianming Technology had the largest increase in margin balance, reaching 13.886 million yuan, a rise of 132.38% from the previous trading day, although its stock price increased by only 0.88%, underperforming the Shanghai index [1] - Other notable stocks with significant margin balance increases included Caneng Power and Fengyuan Co., with increases of 80.22% and 58.92%, respectively [1] Top Margin Balance Increases - The top 20 stocks by margin balance increase averaged a rise of 0.36%, with China West Electric, Jin'an Guoji, and Leshan Power leading with increases of 10.01%, 7.13%, and 7.11%, respectively [2] - Conversely, stocks like C Fengbei, Hopu Co., and Caneng Power saw declines of 14.42%, 7.33%, and 5.06% [2] Margin Balance Decreases - A total of 1,977 stocks experienced a decrease in margin balances, with 218 stocks seeing declines of over 5% [3] - Danan Biology had the largest decrease, with a margin balance of 6.628 million yuan, down by 63.72% from the previous trading day [4] - Other stocks with significant declines included Jingji Zhino and Xianying Technology, with decreases of 34.09% and 27.44%, respectively [4]