另据中信建投（601066）证券，第44届J.P.摩根医疗健康大会（JPM）将于2026年1月12日至15日在旧金 山举行，预计吸引超8000名全球参与者。 作为始于1982年的行业顶级峰会，本届大会将汇聚500多家上 市公司与数千家初创企业，围绕"资本+战略"展开深度交流。该行认为，国内上市药企正迎来创新收获 期，呈现"自主研发+海外BD"双轮驱动格局。整体看，中国药企从"单一市场驱动"转向"全球价值创 造"，JPM大会将成为展示临床数据、洽谈海外合作的核心舞台。 消息面上，1月3日晚间，国家药监局官方微信公号发文称，2025年我国已批准上市的创新药达76个，大 幅超过2024年全年48个，创历史新高。此外，2025年我国创新药对外授权交易总金额超过1300亿美元， 授权交易数量超过150笔，同样创历史新高。 医药股走势强劲。截至发稿，歌礼制药-B(01672)涨9.9%，报12.66港元；科伦博泰生物-B(06990)涨 6.29%，报427.8港元；云顶新耀(01952)涨6.28%，报40.28港元；信达生物(01801)涨5.96%，报83.5港 元；三生制药(01530)涨5.7%，报25.98港 ...

另据中信建投证券，第44届J.P.摩根医疗健康大会（JPM）将于2026年1月12日至15日在旧金山举行，预 计吸引超8000名全球参与者。 作为始于1982年的行业顶级峰会，本届大会将汇聚500多家上市公司与数 千家初创企业，围绕"资本+战略"展开深度交流。该行认为，国内上市药企正迎来创新收获期，呈现"自 主研发+海外BD"双轮驱动格局。整体看，中国药企从"单一市场驱动"转向"全球价值创造"，JPM大会将 成为展示临床数据、洽谈海外合作的核心舞台。 智通财经APP获悉，医药股走势强劲。截至发稿，歌礼制药-B(01672)涨9.9%，报12.66港元；科伦博泰 生物-B(06990)涨6.29%，报427.8港元；云顶新耀(01952)涨6.28%，报40.28港元；信达生物(01801)涨 5.96%，报83.5港元；三生制药(01530)涨5.7%，报25.98港元。 消息面上，1月3日晚间，国家药监局官方微信公号发文称，2025年我国已批准上市的创新药达76个，大 幅超过2024年全年48个，创历史新高。此外，2025年我国创新药对外授权交易总金额超过1300亿美元， 授权交易数量超过150笔，同样创历 ...

Core Viewpoint - The article highlights the unprecedented surge in business development (BD) activities in China's biotech sector, with the total amount of domestic innovative drug licensing exceeding $100 billion by November 18, 2025, marking a doubling compared to 2024. This trend reflects the increasing global competitiveness and value of Chinese pharmaceutical assets, while also prompting a deeper examination of transaction quality and product value realization post-agreement [1][2]. Summary by Sections BD Market Dynamics - The BD market in China is experiencing a significant boom, with a projected compound annual growth rate (CAGR) for external BD activities expected to remain in double digits over the next five years, despite a forecasted decline in growth rate [2]. - Key characteristics of future transactions include an increase in late-stage pipeline contributions and a shift from pure technology transfer to models involving "licensing + co-development + commercialization" [2]. Major Transactions - Notable transactions in 2025 include: - Hengrui Medicine's collaboration with GSK, involving a total potential amount of approximately $120 billion, with an upfront payment of $500 million [3]. - Innovent Biologics' agreement with Takeda, with a potential total of $114 billion and an upfront payment of $1.2 billion [3]. - A record-setting deal between 3SBio and Pfizer, with an upfront payment of $12.5 billion and potential milestone payments reaching $48 billion [5][6]. Global Interest in Chinese Biotech - Chinese innovative drugs are gaining significant traction in global markets, with multinational corporations increasingly sourcing early-stage innovation pipelines from China due to cost-effectiveness and potential efficacy [7][8]. - The trend indicates a shift where Chinese biotech firms are evolving from technology providers to value co-creators in the global pharmaceutical landscape [7]. Transaction Models - The dominant transaction model remains "License-out," which accounted for 91% of upfront payments and 99% of total amounts in related transactions in the first half of the year [10]. - NewCo models are gaining popularity, allowing companies to inject parts of their product pipelines into newly formed entities with foreign capital, reflecting a flexible asset operation strategy [10][11]. Future Outlook - The BD market is expected to continue thriving, driven by the need for multinational companies to replenish their pipelines as many blockbuster drugs face patent expirations, creating a significant market opportunity [15]. - Emerging technologies, particularly in ADCs and bispecific antibodies, are anticipated to dominate future BD transactions, with a notable interest in metabolic and autoimmune products [16][17]. Challenges and Considerations - Despite the growth, challenges remain in ensuring compliance with international standards and protecting intellectual property during global collaborations [13]. - The market is expected to stabilize, with a rational return to expectations regarding BD transactions, as the industry matures and the focus shifts from explosive growth to sustainable value creation [17].

智通财经财经APP获悉，交银国际发布研报称，内地"十五五"开局定调，市场步入政策验证与盈利修复 期。定价权结构演变，新核心资产吸引长线回流。1月重点关注三大变量：1）"十五五"首批重大项目与 增收政策细则；2）海外流动性；3）春节长假前的消费数据与季节性流动性。该行建议，行业配置聚 焦"内需重构"与"出海韧性"，进攻与防御并重。该行1月研选的股份包括：置富产业信托(00778)、英伟 达(NVDA.US)、禾赛-W(02525)、三生制药(01530)、伊利股份(600887.SH)、协鑫科技(03800)。 ...

Core Insights - The surge in BD (business development) transactions in China's innovative pharmaceutical sector is a reflection of the industry's maturation and increasing global recognition, with 2025 marking a significant year for License-out agreements [3][4][5] Group 1: BD Transactions Overview - In December 2025, several Chinese pharmaceutical companies, including Ganli Pharmaceutical and Heng Rui Medicine, announced significant BD agreements, indicating a trend towards increased collaboration and innovation in the sector [2] - The total value of BD transactions for Chinese innovative drugs reached $135.655 billion in 2025, with upfront payments totaling $7 billion, marking a historical high in both transaction volume and value [3] - The number of BD transactions involving Chinese companies and top multinational corporations (MNCs) increased from 3 in 2015 to 35 in 2025, highlighting the growing interest from global players [3] Group 2: Market Dynamics and Future Outlook - The BD transaction boom is expected to continue into 2026, with industry experts predicting sustained high activity levels, although the focus may shift from quantity to value [5][14] - The NewCo model, which allows for "technology equity + capital cooperation," is emerging as a new pathway for Chinese pharmaceutical companies to engage in international markets, although its prevalence may decrease in 2026 [14][15] - The overall trend indicates a shift from isolated transactions to a more collaborative ecosystem, where companies leverage partnerships to enhance their global market presence [16][20] Group 3: Transaction Structures and Strategies - The structure of BD transactions is evolving, with companies increasingly engaging in co-development and co-commercialization agreements, allowing for shared risks and benefits [10][11] - The pricing of BD transactions is becoming more rational, with companies focusing on the clinical value and market potential of their products, which influences upfront payment amounts [19][18] - Legal and advisory services are becoming integral to BD transactions, reflecting the increasing complexity and importance of these deals in the pharmaceutical landscape [17]

Core Viewpoint - The A-share pharmaceutical sector in 2025 exhibits structural differentiation, with innovative drugs and CXO sectors thriving due to overseas demand and business development, while traditional Chinese medicine, medical devices, and pharmaceutical commerce face performance pressures [3][20]. Summary by Category Overall Market Performance - The A-share pharmaceutical and biotechnology sector saw an overall increase of 25.64% from January 1 to December 30, 2025, despite a slight decline in revenue and a stabilization in profits, with total revenue of 18,544.52 billion yuan, down 1.42% year-on-year, and net profit of 1,407.32 billion yuan, down 1.65% year-on-year [4][21]. Innovative Drug Sector - The innovative drug sector was a standout performer in 2025, with the chemical pharmaceutical segment rising by 32.58% and the medical services segment by 32.91% [4][21]. - Companies like BeiGene (百济神州) reported significant growth, achieving revenue of 27.595 billion yuan, a 44.2% increase year-on-year, surpassing the total revenue of 27.21 billion yuan for 2024 [4][22]. Business Development (BD) Trends - The business development landscape for innovative drug companies is evolving, with significant partnerships such as the 11.4 billion USD deal between Innovent Biologics and Takeda, and a 12.5 billion USD collaboration between Hengrui Medicine and GlaxoSmithKline [5][22][24]. - The total value of business development transactions reached approximately 94.158 billion USD in the first three quarters of 2025, significantly exceeding the total for 2024 [25]. CXO Sector Performance - The CXO sector, driven by the demand for innovative drug research, achieved a 32.91% increase in 2025, with total revenue of 1,365.72 billion yuan, up 3.63% year-on-year, and net profit of 209.12 billion yuan, up 36.47% year-on-year [10][27]. - Leading companies like WuXi AppTec (药明康德) and Kanglong Chemical (康龙化成) returned to growth, with WuXi AppTec reporting a revenue increase of 18.61% and net profit growth of 84.84% [28][31]. Traditional Chinese Medicine and Medical Devices - The traditional Chinese medicine sector experienced a modest increase of 6.75% in 2025, with total revenue of 2,590.69 billion yuan, down 4.33% year-on-year, and net profit of 294.99 billion yuan, down 1.53% year-on-year [36]. - The medical device sector reported a revenue of 1,792.10 billion yuan, down 2.24% year-on-year, with notable performance differences among sub-sectors, where companies like Mindray Medical (迈瑞医疗) showed strong overseas revenue growth [33][34].

Core Insights - The year 2025 marks a significant milestone for China's innovative pharmaceutical industry, characterized by intense interactions between capital and industry, with BD transaction totals exceeding $130 billion, setting a historical record and surpassing 50% of the global market share [1][5] - The market has experienced a rollercoaster ride, with a resurgence in the first half of the year followed by a collective pullback in the third quarter, highlighting the importance of distinguishing between companies driven by solid fundamentals versus those reliant on market sentiment [3][10] - The industry is transitioning from "scale expansion" to "value realization," indicating a shift towards more sustainable growth and resilience in the face of external uncertainties [1][12] BD Transactions - In 2025, China saw explosive growth in license-out transactions, with over 100 deals totaling more than $110 billion, including 15 transactions with upfront payments exceeding $100 million [5][6] - Notable milestone BD transactions include a $12.5 billion deal between 3SBio and Pfizer, and a $114 billion strategic partnership between Innovent Biologics and Takeda, marking a shift in traditional licensing models [5][6] - The total value of license-out transactions reached $130 billion, a year-on-year increase of over 150%, underscoring China's emergence as a key player in global pharmaceutical innovation [5][6] Market Dynamics - The traditional pharmaceutical companies are adapting and showing resilience, with firms like Hengrui Medicine and 3SBio successfully navigating the transition from generics to innovative drugs [4][10] - The industry is expected to continue its upward trajectory, supported by increased R&D investments, a growing number of clinical trials, and a dual payment system that enhances patient access to innovative therapies [10][11] - The anticipated "data validation year" in 2026 will see more Chinese innovative pipelines entering global clinical development, influencing market expectations for Chinese innovation [10][11] Future Outlook - The innovative pharmaceutical sector is poised for a more solid and resilient future, with a focus on delivering effective treatment solutions for patients and contributing to the global pharmaceutical landscape [12][13] - The ongoing demand for innovative assets from multinational corporations (MNCs) is expected to rise, driven by patent expirations and declining R&D efficiency, leading to a strategic focus on "in China for global" initiatives [6][7] - The industry is entering a new era characterized by value-driven growth, where the emphasis will be on the contribution of products to revenue rather than mere availability [7][9]

来源：证券时报 作者：许盈 | | 券商金股组合2025年收益排名 | | | --- | --- | --- | | | (截至12月29日) | | | 排名 | 存商 | 累计收益率 | | 1 | 国元证券月度金股 | 83.73% | | 2 | 东北证券月度金股 | 67.47% | | 3 | 开源证券月度金股 | 67.00% | | ব | 东兴证券月度金股 | 61.53% | | 5 | 华鑫证券月度金股 | 60.67% | | 6 | 招商证券月度金股 | 60.31% | | 7 | 光大证券月度金股 | 55.50% | | 8 | 东莞证券月度金股 | 51.82% | | ਰੇ | 国泰海通月度金股 | 51.62% | | 10 | 长城证券月度金股 | 50.95% | 证券时报记者 许盈 每市APP显示，截至12月29日收盘，共有10家券商推荐的金股组合年内录得了超过50%（收益率计算规 则：将券商推荐的月度金股等权编制成指数，每月调仓）的收益率。 具体来看，来自国元证券的金股组合收益率最高，为83.73%；东北证券、开源证券的金股组合以 67.47%、67%的收益率分 ...

证券时报记者 许盈 2025年收官在即，券商金股也在一波三折的年度长阳行情中脱颖而出。 数据显示，截至12月29日，今年有10家券商的金股组合取得了超过50%的亮眼收益。提早在低位挖掘相关个股并 持续向市场推荐，是不少券商斩获超额战绩的秘诀。比如，某券商自低位起连续4个月推荐新易盛，完整地吃到了 该股超4倍的涨幅。 值得一提的是，腾讯控股以每月获7家左右券商推荐的超高人气，荣登年度最热门金股。 10家券商金股收益率超50% 每市APP显示，截至12月29日收盘，共有10家券商推荐的金股组合年内录得了超过50%（收益率计算规则：将券商 推荐的月度金股等权编制成指数，每月调仓）的收益率。 具体来看，来自国元证券的金股组合收益率最高，为83.73%；东北证券、开源证券的金股组合以67.47%、67%的 收益率分列第二、三名；东兴证券、华鑫证券、招商证券的金股组合也都取得了超过60%的收益率。此外，光大 证券、东莞证券、国泰海通、长城证券的金股组合，收益率均在50%以上。 近几年，经过加码发展，券商金股已成为多家券商研究所一项成熟的金牌业务——以每月一期（通常为10只股 票），展示券商最为看好的标的。作为券商月度策略 ...

Group 1: Market Overview - The CITIC Pharmaceutical Index increased by 1.2% during the week of June 3-6, 2025, outperforming the CSI 300 Index by 0.3 percentage points, ranking 16th among CITIC's primary industry classifications [1] - Year-to-date, the CITIC Pharmaceutical and Biotechnology Index has risen by 8.3%, surpassing the CSI 300 Index by 9.9 percentage points, ranking 5th among CITIC's industry classifications [1] - The top five performing stocks for the week included Yiming Pharmaceutical (+33.09%), Wanbangde (+32.59%), Anglikang (+30.28%), Xinnowei (+21.36%), and Haichen Pharmaceutical (+20.93%) [1] Group 2: Patent Cliff and Market Opportunities - By 2037, 27 blockbuster drugs with projected sales exceeding $4 billion in 2024 will face patent expiration, creating a market opportunity of over $240 billion for new entrants [2][12] - China is positioned as a core player in global innovative drug supply, leveraging its technological platforms and research efficiency, with the highest number of clinical pipelines in cell therapy, ADC, and bispecific antibodies [2][21] - The projected revenue from licensing agreements for Chinese projects from 2020 to 2025 is estimated to generate approximately $8.2 billion in net profit, translating to a potential market capitalization increase of $81.7 billion based on a 10x PE ratio [2] Group 3: Investment Recommendations - Focus on authorized blockbuster products with overseas clinical progress, including companies like Kangfang Biotech, Kelun Biotech, and Sanofi [2] - Potentially significant products for licensing out include Innovent Biologics, CSPC Pharmaceutical Group, and Zai Lab [2] - Companies with approved products showing strong commercialization performance include BeiGene, Kingsoft Biotech, and Hutchison China MediTech [2] Group 4: Mid to Long-term Investment Strategy - The investment strategy emphasizes three main lines: innovation, recovery, and policy support [4] - The innovation line focuses on biopharmaceuticals with competitive advantages in international markets and companies with second growth curves in pharmaceuticals [4] - The recovery line anticipates a rebound in medical device tenders and consumer healthcare, while the policy line supports high-dividend companies and encourages mergers and acquisitions [4]