Core Insights - The biotechnology sector in the Hong Kong stock market has shown strong performance, with several stocks experiencing significant gains today, particularly药捷安康-B which surged over 30% [1] Stock Performance Summary - 药捷安康-B: Increased by 31.25%, latest price at 218.000, total market value of 86.524 billion, year-to-date increase of 1557.79% [2] - 康宁杰瑞制药-B: Increased by 7.15%, latest price at 14.680, total market value of 14.245 billion, year-to-date increase of 319.43% [2] - 帝王国际投资: Increased by 5.50%, latest price at 0.115, total market value of 0.0213 billion, year-to-date increase of 155.56% [2] - 映恩生物-B: Increased by 5.00%, latest price at 336.000, total market value of 29.58 billion, year-to-date increase of 255.18% [2] - 基石药业-B: Increased by 4.66%, latest price at 7.190, total market value of 10.612 billion, year-to-date increase of 212.61% [2] - 三叶草生物-B: Increased by 4.39%, latest price at 2.140, total market value of 2.776 billion, year-to-date increase of 787.97% [2] - 百奥塞图-B: Increased by 3.86%, latest price at 24.220, total market value of 9.673 billion, year-to-date increase of 184.94% [2] - 来凯医药-B: Increased by 3.71%, latest price at 14.540, total market value of 6.49217 billion, year-to-date increase of 55.18% [2] - 君实生物: Increased by 3.29%, latest price at 27.600, total market value of 28.337 billion, year-to-date increase of 138.34% [2] - MIRXES-B: Increased by 3.26%, latest price at 72.900, total market value of 20.145 billion, year-to-date increase of 212.88% [2]

Core Viewpoint - The China Securities Regulatory Commission has approved the A-share issuance registration application for the company on October 15, 2025 [1] Group 1 - The company is set to issue A-shares following the approval from the regulatory authority [1]

Core Viewpoint - The company, Baiaosaitu-B (02315.HK), has received approval from the China Securities Regulatory Commission (CSRC) for its A-share issuance registration application, effective October 15, 2025 [1] Group 1 - The approval marks a significant milestone for the company in its efforts to expand its capital base through A-share issuance [1] - The registration approval is expected to enhance the company's financial flexibility and support its growth strategies [1]

Core Viewpoint - Baiaosaitu (Beijing) Pharmaceutical Technology Co., Ltd. has successfully registered its IPO on the Sci-Tech Innovation Board, marking a significant milestone for the company in its growth trajectory [1] Company Overview - Established in 2009, Baiaosaitu is a preclinical CRO and biotechnology company [1] - The company offers various innovative animal models and preclinical pharmaceutical research and development services based on its proprietary gene editing technology [1] Technology and Services - Baiaosaitu utilizes its self-developed RenMice fully human antibody mouse platform, which includes multiple series such as RenMab, RenLite, RenNano, RenTCR, and RenTCR-mimic [1] - The platform targets nearly a thousand potential drug targets in the human body for large-scale drug discovery and development [1] - The company has plans to transfer, license, or co-develop promising antibody molecules [1] IPO Journey - The IPO application for Baiaosaitu was accepted on June 20, 2023, and the company passed the review on September 24, 2023 [1] - The registration for the IPO was submitted on September 26, 2023 [1]

Core Viewpoint - The China Securities Regulatory Commission has approved the A-share issuance registration application for Baiaosaitu-B (02315) on October 15, 2025 [1] Group 1 - The approval marks a significant step for the company in accessing the A-share market [1]

（股份代號：2315） 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示，概不就因本公告全部或任何部份內容而產生或因依 賴該等內容而引致的任何損失承擔任何責任。 BIOCYTOGEN PHARMACEUTICALS (BEIJING) CO., LTD. A股發行註冊獲中證監批准之公告 本公告由百奧賽圖（北京）醫藥科技股份有限公司（「本公司」）遵照香港聯合交易所 有限公司證券上市規則（「上市規則」）第13.09(2)(a)條及證券及期貨條例（香港法 例第571章）第XIVA部的內幕消息條文（定義見上市規則）而發出。 茲提述本公司日期為2023年3月6日、2023年3月15日、2023年6月20日及2025年9 月17日及2025年9月24日的公告及日期為2023年3月31日的通函，當中載有（其中 包括）建議首次公開發行A股（「建議A股發行」）並在上海證券交易所（「上交所」） 科創板上市的相關事宜。除另有界定者外，本公告所用詞彙與上述公告及通函所 界定者具有相同涵義。 百奧賽圖（北京）醫藥科技股份有限公司 （於中華人民共和國註冊成立的股份有 ...

Core Viewpoint - The China Securities Regulatory Commission (CSRC) has approved the initial public offering (IPO) registration application of Bai Aosai Tu (Beijing) Pharmaceutical Technology Co., Ltd. for listing on the Sci-Tech Innovation Board [1] Company Summary - Bai Aosai Tu is set to launch its IPO, indicating a significant step towards raising capital for its operations and growth [1] - The approval from the CSRC reflects the company's compliance with regulatory requirements and its readiness for public investment [1] Industry Summary - The approval of IPOs in the biotech sector, such as Bai Aosai Tu, highlights the growing interest and investment potential in the pharmaceutical technology industry in China [1] - The listing on the Sci-Tech Innovation Board is part of China's broader strategy to support innovative companies and enhance the development of the biotech industry [1]

Group 1 - The China Securities Regulatory Commission (CSRC) has approved the registration application for the initial public offering (IPO) of Bai Ao Sai Tu (Beijing) Pharmaceutical Technology Co., Ltd. on the STAR Market [1] - This approval marks a significant step for the company in its efforts to raise capital and expand its operations in the pharmaceutical sector [1] - The listing on the STAR Market is expected to enhance the company's visibility and credibility in the industry [1]

Core Viewpoint - The company Bai Aosai Tu is on the verge of achieving a dual listing in Hong Kong and on the Sci-Tech Innovation Board, with its IPO registration submitted to the China Securities Regulatory Commission after passing the review [3][4]. Company Overview - Bai Aosai Tu, established in 2009, focuses on preclinical CRO services and biopharmaceuticals, including antibody development and drug discovery based on mouse models [5]. - The company reported revenues of approximately 534 million yuan, 717 million yuan, and 980 million yuan for the years 2022, 2023, and 2024, respectively, with net profits of -602 million yuan, -383 million yuan, and 33.54 million yuan during the same period [5][6]. Financial Performance - The company experienced significant losses in 2022 and 2023 due to high R&D expenditures in antibody and new drug development, which have not yet generated substantial revenue [6]. - Bai Aosai Tu's gross profit margins were 73.38%, 70.59%, and 77.67% for 2022, 2023, and 2024, respectively, while net profit margins were -112.79%, -53.42%, and 3.42% [5]. R&D Investment - R&D expenditures decreased from approximately 699 million yuan in 2022 to 324 million yuan in 2024, representing 130.96%, 66.17%, and 33.04% of revenue for those years [9][10]. - The number of R&D personnel dropped from 627 in 2022 to 337 in 2024, with a significant reduction in full-time R&D staff [9][10]. Business Segments - The sales revenue from model animals is projected to grow from approximately 169 million yuan in 2022 to 389 million yuan in 2024, becoming the largest revenue source for the company [6][7]. - The antibody development business is also expected to grow, with revenues of approximately 127 million yuan, 176 million yuan, and 318 million yuan from 2022 to 2024, respectively [7]. Strategic Adjustments - The company has shifted its strategy to focus on partnerships for drug development, reducing its own R&D costs while increasing revenue from antibody development [6][11]. - Bai Aosai Tu aims to maintain a strong technological foundation and innovation capability, with plans to continue investing in R&D in line with business development and cash flow forecasts [4][11].

股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年9月30日 狀態: 新提交 致：香港交易及結算所有限公司 | 2. 股份分類 | 普通股 | 股份類別 | 其他類別 (請註明) | | | 於香港聯交所上市 (註1) | 否 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | - | 說明 | 非上市股份 | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 288,616,500 | RMB | | 1 RMB | | 288,616,500 | | 增加 / 減少 (-) | | | 0 | | | RMB | | | | 本月底結存 | | | 288,616,500 | RMB | | 1 RMB | | 288,616,500 | 本月底法定/註冊股本總額： RMB 399,398,420 FF301 第 1 頁 共 10 頁 v 1.1.1 公司名稱: 百奧賽圖(北京) ...