Financial Performance - Q1 2025 revenue increased by 210% year-over-year, reaching RMB 965 billion[13] - Adjusted non-IFRS net profit increased by 400% year-over-year, reaching RMB 268 billion[13] - Backlog for continuing operations increased by 471% year-over-year, reaching RMB 5233 billion[13] - Q1 2025 operating cash flow increased by 418% year-over-year, reaching RMB 303 billion[42] Segment Performance - WuXi Chemistry Q1 revenue increased by 329% year-over-year, reaching RMB 739 billion[19, 22] - TIDES revenue within WuXi Chemistry increased by 1876% year-over-year, reaching RMB 224 billion[19, 22] - WuXi Testing lab testing services revenue decreased by 49% year-over-year, reaching RMB 088 billion[26, 29] - WuXi Biology Q1 revenue increased by 82% year-over-year, reaching RMB 061 billion[30, 32] Regional Revenue - US revenue contribution is 66%, with RMB 638 billion, a 284% increase[16] - Europe revenue contribution is 13%, with RMB 130 billion, a 262% increase[16] - China revenue contribution is 16%, with RMB 153 billion, a 13% decrease[16] - Japan, Korea & Others revenue contribution is 5%, with RMB 045 billion, a 30% increase[16]

Financial Data and Key Metrics Changes - Revenue from continuing operations grew 23.1% year over year to RMB9.39 billion, while total revenue achieved RMB9.65 billion, representing a 21% year over year growth [9] - Adjusted non-IFRS net profit grew 40% year over year to RMB2.68 billion, with a record backlog for continuing operations of RMB52.33 billion, growing 47.1% year over year [9][10] - Adjusted IFRS gross profit margin reached 41.9%, with net profit attributable to the owners of the company increasing by 89.1% year over year [26][27] Business Line Data and Key Metrics Changes - Wuxi Chemistry's CRDMO business revenue grew 32.9% year over year to RMB7.39 billion, with adjusted non-IFRS gross profit margin improving 4.2 percentage points year over year to 47.5% [11][12] - Small molecule DNM business revenue grew 13.8% year over year to RMB3.85 billion, with both Changzhou and Taishin API manufacturing sites passing FDA inspections [13] - Tides business achieved RMB2.24 billion revenue in the first quarter, representing a strong growth of 187.6% year over year [14] Market Data and Key Metrics Changes - Revenue from the U.S. market grew 28.4% year over year, while revenue from Europe grew 26.2% year over year; however, China showed a slight decline [10] - Revenue generated from clinical CRO and SMO business was down 2.2% year over year to RMB0.61 billion, attributed to market price impact [21][22] Company Strategy and Development Direction - The company will continue to focus on the CRDMO business model with an emphasis on operational efficiency and exceptional services [29] - Full year guidance is maintained, expecting revenue from continuing operations to resume double-digit growth of 10% to 15% year over year, targeting total revenue of RMB41.5 billion to RMB43 billion [30] - The company plans to accelerate global D and M capacity expansion, with CapEx expected to reach RMB7 billion to RMB8 billion [30] Management Comments on Operating Environment and Future Outlook - Management expressed confidence in maintaining full year guidance despite external uncertainties, emphasizing the importance of operational resilience [30][31] - The company is committed to rewarding shareholders with a proposed 30% annual cash dividend payout ratio and additional one-time special cash dividend [31][32] Other Important Information - The company has successfully supported about 40% of successful out-licensing deals from Chinese biotech since 2022 [20] - The total amount of cash dividends and share repurchases is expected to exceed RMB6 billion, accounting for more than 60% of the company's net profit attributable to owners in 2024 [32] Q&A Session Summary Question: What are the key drivers behind the robust growth in Tides? - The growth is attributed to both strong demand and capacity ramping up from a low base last year [37] Question: How does the company view the impact of tariffs on business segments? - Tariffs are seen as a systemic challenge, with less than 10% of total revenue coming from exports to the U.S. [45][46] Question: What is the projected CapEx for 2025 and its allocation? - Projected CapEx is RMB7 billion to RMB8 billion, primarily for expanding D and M manufacturing capacity in various locations [50][54] Question: How does the company plan to address pricing pressures in testing and biology segments? - The company aims to focus on contracts with higher margins and differentiate its services to improve margins gradually [68] Question: What is the expected contribution from late-stage D and M projects in the next few years? - Specific numbers are difficult to provide, but the CRDMO business model is expected to sustain growth through a strong pipeline [71]

FANGDA PARTNERS http://www.fangdalaw.com 中国北京市朝阳区光华路一号 电子邮件 E-mail: email@fangdalaw.com 北京嘉里中心北楼 27 层 电 话 Tel.: 86-10-5769-5600 邮政编码：100020 传 真 Fax: 86-10-5769-5788 27/F，North Tower, Beijing Kerry Centre 1 Guanghua Road, Chaoyang District Beijing 100020, PRC 上海市方达（北京）律师事务所 关于无锡药明康德新药开发股份有限公司 2024 年年度股东大会、2025 年第一次 A 股类别股东会议及 2025 年第一次 H 股类别股东会议的法律意见书 致：无锡药明康德新药开发股份有限公司 上海市方达（北京）律师事务所（以下简称"本所"）是具有中华人民共和国 境内法律执业资格的律师事务所。根据相关法律顾问协议，本所指派律师出席无 锡药明康德新药开发股份有限公司（以下简称"药明康德"或"公司"）2024 年年度 股东大会、2025 年第一次 A 股类别股东会议及 20 ...

无锡药明康德新药开发股份有限公司 章 程 (2025年修订) | 第一章 | 总则 1 | | --- | --- | | 第二章 | 经营宗旨和范围 2 | | 第三章 | 股份 3 | | 第一节 | 股份发行 3 | | 第二节 | 股份增减和回购 5 | | 第三节 | 股份转让 7 | | 第四节 | 购买公司股份的财务资助 9 | | 第五节 | 股票和股东名册 9 | | 第四章 | 股东和股东大会 11 | | 第一节 | 股东 11 | | 第二节 | 股东大会的一般规定 13 | | 第三节 | 股东大会的召集 17 | | 第四节 | 股东大会的提案与通知 19 | | 第五节 | 股东大会的召开 20 | | 第六节 | 股东大会的表决和决议 23 | | 第七节 | 类别股东表决的特别程序 27 | | 第五章 | 董事会 29 | | 第一节 | 董事 29 | | 第二节 | 独立董事 32 | | 第三节 | 董事会 34 | | 第六章 | 经理（总裁、首席执行官）及其他高级管理人员 40 | | 第七章 | 监事会 43 | | 第一节 | 监事 43 | | 第二节 | ...

董事會包括執行董事李革博士、陳民章博士、胡正國先生、楊青博士及張朝暉先生；非執行董事童小幪先生及吳亦兵博士；以及獨 立非執行董事盧韶華女士、俞衛博士、張新博士、詹智玲女士及冷雪松先生。 | | 股東類型 | 稅率 | 有關代預扣所得稅之更多補充 | | --- | --- | --- | --- | | | | | （如適用） | | | 非居民企業 | | | | | （非中國內地登記地址） | 10% | 本公司向名列於本公司H股股東名 | | | | | 冊上的非居民企業股東派發年度股 | | | | | 息前，有義務代扣代繳企業所得 | | | | | 稅，稅率為10%。任何以非個人股 | | | | | 東名義，包括以香港中央結算（代 | | | | | 理人）有限公司、其他代理人或受 | | | | | 託人，或其他組織及團體名義登記 | | | | | 的H股股份均被視為非居民企業股 | | | | | 東所持的H股股份，其應得的股息 | | | | | 將被扣除中國企業所得稅。 | | | 於香港聯交所投資本公司A股 | 10% | 本公司按照10%的稅率代扣所得 | | 股票 | | | 稅 ...

EF001 免責聲明 | 公告全部或任何部份內容而產生或因倚賴該等內容而引致的任何損失承擔任何責任。 | 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性或完整性亦不發表任何聲明，並明確表示，概不對因 | | | | --- | --- | --- | --- | | 股票發行人現金股息公告 | | | | | 發行人名稱 | 無錫藥明康德新藥開發股份有限公司 | | | | 股份代號 | 02359 | | | | 多櫃檯股份代號及貨幣 | 不適用 | | | | 相關股份代號及名稱 | 05265 WXAT B2510 | | | | 公告標題 | 2024年股東週年大會通函 | | | | 公告日期 | 2025年4月29日 | | | | 公告狀態 | 更新公告 | | | | 更新/撤回理由 | 現金股息派發日落實 | | | | 股息信息 | | | | | 股息類型 | 末期 | | | | 股息性質 | 普通股息 | | | | 財政年末 | 2024年12月31日 | | | | 宣派股息的報告期末 | 2024年12月31日 | | | | 宣派股息 | ...

FF305 翌日披露報表 (股份發行人 ── 已發行股份或庫存股份變動、股份購回及/或在場内出售庫存股份) 表格類別： 股票 狀態： 新提交 | 1). | 購回股份(或其他證券)但沒有註銷 | 379,300 | 0.02 % | RMB | 52.75 | | --- | --- | --- | --- | --- | --- | | | 茲提述本公司於2025年4月8日刊發的公告。 | | | | | | | 於2025年4月18日，本公司實施2025年第二次股份回購，并回購 | | | | | | | 379,300股A股股份。 | | | | | | | 變動日期 2025年4月18日 | | | | | | 2). | 購回股份(或其他證券)但沒有註銷 | | | | | | | | 374,000 | 0.01 % | RMB | 53.5 | | | 茲提述本公司於2025年4月8日刊發的公告。 | | | | | | | 於2025年4月21日，本公司實施2025年第二次股份回購，并回購 | | | | | | | 374,000股A股股份。 | | | | | | | 變動日期 2025年 ...

Investment Rating - The report maintains a "Buy" rating for WuXi AppTec (603259) [2] Core Insights - WuXi AppTec reported a significant revenue increase of 21.0% year-on-year, reaching 9.65 billion yuan in Q1 2025, with a notable 89.1% growth in net profit attributed to one-time investment gains [5][8] - The company has a strong order backlog of 52.33 billion yuan, reflecting a 47.1% year-on-year increase, with TIDES orders growing by 105.5% [8] - The company plans to distribute a special dividend of 1 billion yuan in addition to maintaining a 30% annual cash dividend ratio, alongside a share buyback of 1 billion yuan [8] Financial Data and Profit Forecast - Total revenue projections for 2025 are estimated at 42.77 billion yuan, with a year-on-year growth rate of 9.0% [7] - The forecasted net profit for 2025 is 11.27 billion yuan, representing a 19.3% increase compared to the previous year [7] - The report anticipates a continued double-digit growth trajectory for the company's core business, with overall revenue expected to reach between 41.5 billion and 43 billion yuan [8]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確 性或完整性亦不發表任何聲明，並表明概不對因本公告全部或任何部分內容而產生或因倚賴 該等內容而引致的任何損失承擔任何責任。 WUXI APPTEC CO., LTD. * 無錫藥明康德新藥開發股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：2359） (1) 2024年股東週年大會、2025年第一次A股類別股東大會和 2025年第一次H股類別股東大會投票結果； (2) 派付末期股息及特別股息； 及 (3) 修訂公司章程 茲提述(i)無錫藥明康德新藥開發股份有限公司（「本公司」）於2025年3月26日刊 發的通函（「通函」）；及(ii)於2025年3月26日刊發的2024年股東週年大會（「2024年 股東週年大會」）通告（「2024年股東週年大會通告」）及於2025年3月26日刊發的 本公司2025年第一次H股類別股東大會（「2025年第一次H股類別股東大會」）通告 （連同2024年股東週年大會通告，統稱為「該等通告」）。除非文義另有所指，否 則本公告已界定的詞語在通函及該等通告中具有相同涵義。 本公司董事（「 ...

Investment Rating - The investment rating for WuXi AppTec (603259) is "Buy" [5] Core Views - The company's Q1 2025 performance exceeded market expectations, with a revenue of 9.655 billion yuan, a year-on-year increase of 20.96%, and a net profit attributable to shareholders of 3.672 billion yuan, up 89.06% year-on-year [1][2] - The TIDES business significantly contributed to the core performance elasticity, with a revenue of 2.24 billion yuan, representing a remarkable growth of 187.6% year-on-year [2] - The company has a strong order backlog of 52.33 billion yuan, a year-on-year increase of 47.1%, indicating a continued high growth trend [2] Summary by Sections Financial Performance - For Q1 2025, the company achieved a revenue of 9.655 billion yuan, a 21.0% increase year-on-year, with adjusted profit reaching 2.68 billion yuan, up 40% [2] - The chemical business generated 7.39 billion yuan in revenue, a 32.9% increase year-on-year, while the small molecule CDMO business saw a revenue of 3.85 billion yuan, growing 13.8% [2] - The testing and biology segments reported revenues of 1.29 billion yuan and 610 million yuan, showing a decline of 4% and an increase of 8.2% respectively [2] Future Outlook - The company expects a revenue growth guidance of 10% to 15% for its continuing operations in 2025, supported by rapid order growth and ongoing cost reduction efforts [2] - The adjusted revenue forecasts for 2025-2027 are 42.724 billion yuan, 49.093 billion yuan, and 56.747 billion yuan respectively, with EPS estimates of 4.17 yuan, 4.94 yuan, and 5.85 yuan [3][8] Valuation Metrics - The PE ratios for 2025, 2026, and 2027 are projected to be 15, 12, and 10 respectively, based on the closing price of 60.45 yuan per share on April 29, 2025 [3]