股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年12月31日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: 艾迪康控股有限公司 呈交日期: 2026年1月5日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 09860 | 說明 | | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | | 法定/註冊股本 | | | 上月底結存 | | | 2,500,000,000 | USD | | 0.00002 | USD | | 50,000 | | 增加 / 減少 (-) | | | 0 | | | | USD | | | | 本月底結存 | | | 2,500,000,000 | USD | | 0.00002 | USD | | 50,000 | 本月底法定/註冊股本 ...

11月21日下午，由华夏时报社主办的"2025第五届华夏大健康产业发展暨康复服务大会"在北京成功举 行。本次大会以"智领健康未来"为主题，汇聚产业界、学术界、研究机构及投资方等多方代表，旨在整 合全链条资源，把脉行业趋势，探索发展路径。 现场设置了多场高水平圆桌对话，聚焦创新药、脑机接口、AI医疗、中医药转化等前沿议题，深入探 讨行业热点与突破方向。会议还集中发布并展示了一批具有示范意义与前瞻价值的创新典型案例，涵盖 赋能美好生活、ESG、创新药、中医药、生物科技、AI医疗、硬核科技与社会心理服务等八大类别，从 企业实践、技术应用、品牌建设与人物故事等多维度，展现了大健康领域的活力、深度与创新成果。 文/华夏大健康研究院 晶泰控股（2228.HK）是一家基于量子物理、人工智能赋能、机器人技术和大数据驱动的创新药物及新 材料研发平台。2015年由三位麻省理工学院博士后创立，公司利用"AI+机器人+数据"，打造了AI4S垂 直领域超级大模型，提供药物及材料科学研发解决方案及服务。晶泰为全球前20大国际药企中的17家提 供AI药物研发服务。特别地，晶泰加速了辉瑞新冠口服药paxlovid提前6个月上市；与DoveT ...

致：香港交易及結算所有限公司 公司名稱: 艾迪康控股有限公司 股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年11月30日 狀態: 新提交 呈交日期: 2025年12月4日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | | 於香港聯交所上市 (註1) | | 是 | | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 09860 | 說明 | | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | | 法定/註冊股本 | | | 上月底結存 | | 2,500,000,000 | | USD | | 0.00002 | USD | | 50,000 | | 增加 / 減少 (-) | | | 0 | | | | USD | | | | 本月底結存 | | | 2,500,000,000 | USD | | 0.00002 | USD | | 50,000 | 本月底法定/註冊股 ...

Summary of Key Points Core Viewpoint - As of November 26, a total of 39 stocks reached their 52-week highs, with notable performances from Fire Rock Holdings (02975), Crocodile Garments (02977), and Aisuo Holdings (08585) showing significant increases in their high rates [1]. 52-Week Highs - Fire Rock Holdings (02975) achieved a closing price of 0.114 with a peak of 0.231, marking a high rate of 285.00% - Crocodile Garments (02977) closed at 0.085, reaching a high of 0.189, reflecting a high rate of 170.00% - Aisuo Holdings (08585) closed at 0.021, with a peak of 0.040, resulting in a high rate of 110.53% - Other notable stocks include: - Fulltech Electric Group Holdings (01750) with a high rate of 23.64% - Century United Holdings (01959) at 22.05% - Cassava Resources (00841) at 20.19% [1]. 52-Week Lows - The stock with the largest decline was Jia Jin Investment International (00310), which closed at 0.141, reaching a low of 0.137, resulting in a decline rate of -25.95% - Crown Central Properties (00193) closed at 0.168, with a low of 0.141, reflecting a decline rate of -18.02% - Lion Holdings (02562) had a closing price of 4.710, with a low of 4.680, showing a decline rate of -9.48% - Other significant declines include: - Huading Holdings (03398) at -7.14% - XL Two South Strategy - U (09799) at -5.96% [2].

Summary of Key Points Core Viewpoint - As of November 21, 14 stocks reached their 52-week highs, with Hengfa Optical (01134), Chaowei Holdings (08059), and Cassava Resources (00841) leading the gains at 42.11%, 30.56%, and 22.49% respectively [1]. 52-Week Highs - Hengfa Optical (01134) closed at 0.375, with a peak price of 0.540, marking a 42.11% increase [1]. - Chaowei Holdings (08059) closed at 0.030, reaching a high of 0.047, reflecting a 30.56% rise [1]. - Cassava Resources (00841) closed at 0.200, with a maximum price of 0.207, indicating a 22.49% increase [1]. - Other notable stocks include Sibor Systems (08319) at 15.04%, MOS HOUSE (01653) at 11.46%, and Tianjin Jianfa (02515) at 5.19% [1]. 52-Week Lows - China Pengfei Group (03348) reached a low of 1.100, down 20.09% from its peak [1]. - China Information Technology (08178) closed at 0.285, reflecting a 19.35% decrease [1]. - XL Ernan Strategy - U (09799) saw a decline of 14.27% [1]. - Other significant declines include Hesai - W (02525) at -10.54% and MBC Bitcoin - U (03425) at -9.09% [1]. Additional Notable Stocks - Stocks like MBC Bitcoin (03430) and Tongyuan Kang Pharmaceutical - B (02410) also experienced declines of 6.64% and 6.62% respectively [2]. - The overall trend indicates a mix of significant gains in certain stocks while others are facing substantial losses, reflecting a volatile market environment [1][2].

Core Insights - The recent acquisition activity in the CRO sector highlights a trend of significant capital investments, with notable transactions including Hillhouse Capital's acquisition of WuXi AppTec's clinical CRO business for 2.8 billion yuan and Eddiecon Holdings' announcement to acquire Crown Bioscience for approximately 204 million USD [1][2] Group 1: Acquisition Details - Eddiecon Holdings plans to acquire 100% of Crown Bioscience, a leading oncology-focused CRO, with the transaction expected to be completed by mid-2026 [1] - Crown Bioscience, established in 2006, is recognized as the largest oncology specialty CRO globally, boasting a leading patient-derived xenograft (PDX) model library and organoid technology, along with over 5,000 high-quality in vivo and in vitro tumor models [1] Group 2: Financial Metrics and Valuation - The transaction's EV/EBITDA multiple is approximately 7 times, significantly lower than the over 50 times multiples seen in other preclinical CRO companies, indicating a notable valuation advantage [2] - This acquisition marks Eddiecon's strategic shift from the ICL sector to a dual focus on "clinical testing + drug development services," potentially reshaping the global pharmaceutical R&D service landscape [2] Group 3: Growth Potential - The acquisition is expected to inject new growth momentum into Eddiecon, as the stable cash flow from its independent clinical laboratory (ICL) business will complement the high-profit margin CRO services of Crown Bioscience, creating a more balanced and scalable business model [2] - Eddiecon's projected net profit for 2025-2027 is estimated at 56 million, 67 million, and 94 million yuan, reflecting year-on-year growth rates of 19.79%, 18.59%, and 41.47% respectively, with the company receiving an "overweight" rating from the securities firm [2]

Group 1 - The core viewpoint of the news highlights the recent surge in capital acquisitions within the CRO sector, with notable transactions including Hillhouse Capital's investment of 2.8 billion yuan in WuXi AppTec's clinical CRO business and Eddycon Holdings' announcement to acquire Crown Bioscience for approximately 204 million USD [1][2] - Eddycon Holdings plans to acquire 100% of Crown Bioscience, a leading oncology-focused CRO, which boasts a comprehensive library of patient-derived xenograft (PDX) models and organoid technology, along with over 5,000 high-quality in vivo and in vitro tumor models [1] - The acquisition is expected to be completed by mid-2026, marking a strategic shift for Eddycon from the ICL field to a dual-track model of "clinical testing + drug development services" [1][2] Group 2 - The transaction's EV/EBITDA multiple is approximately 7 times, significantly lower than the over 50 times multiples seen in the preclinical CRO sector, indicating a notable valuation advantage [2] - This acquisition is anticipated to inject new growth momentum into Eddycon, as the stable cash flow from its independent clinical laboratory (ICL) business will complement the high-margin CRO services of Crown Bioscience, creating a more balanced and scalable business model [2] - Eddycon's projected net profit for 2025-2027 is estimated at 56 million, 67 million, and 94 million yuan, reflecting year-on-year growth rates of 19.79%, 18.59%, and 41.47% respectively, with the company receiving an "overweight" rating from Industrial Securities [2]

Core Insights - The acquisition of Crown Bioscience by Adicon Holdings marks a strategic shift from ICL to a dual focus on "clinical testing + drug development services" [1][9] - The deal is valued at approximately $204 million, with an EV/EBITDA multiple of around 7, significantly lower than the industry average of over 50 for similar companies [1][9] Timing - The macro environment and industry policies are creating a favorable window for the transaction, with a resurgence in global pharmaceutical R&D and a growing demand for outsourcing services [2] - The CRO market is projected to grow from $98.4 billion in 2024 to $139.8 billion by 2029, with China being a key growth driver [2] Location - Adicon's acquisition targets the high-growth oncology CRO sector, which is experiencing rapid expansion due to high R&D investments and outsourcing penetration [4] - Crown Bioscience is recognized as a leading oncology CRO with a unique asset advantage, including a vast library of patient-derived xenograft (PDX) models and over 5,000 high-quality tumor models [4][5] People - The strategic vision of both companies aligns well, supported by the backing of Carlyle Group, which enhances the transaction's potential for long-term value creation [6][7] - The merger will enable a comprehensive end-to-end service from target discovery to clinical trials, significantly improving drug development efficiency [6][7] Financial Impact - The acquisition is expected to contribute approximately 28% to Adicon's total revenue, facilitating its transition from a local leader to a global integrated laboratory service platform [7][8] - The combination of Adicon's clinical data and Crown's preclinical capabilities will create a robust data resource for AI-driven drug discovery and patient stratification [8] Industry Implications - This acquisition could reshape the landscape of the ICL and CRO industries in China, prompting local companies to pursue cross-border competition and global integration [9] - The collaboration between Adicon and Crown Bioscience is anticipated to establish a new force in the global pharmaceutical R&D services sector [9]

Core Insights - Eddycon Holdings Limited has signed a definitive share purchase agreement to acquire all issued shares of Crown Bio for $204 million, including performance-related payments, with the transaction expected to close by mid-2026 [1][2] - The acquisition aims to enhance Eddycon's R&D capabilities in high-growth therapeutic areas, capitalizing on the increasing demand for precision diagnostics in China and global biopharmaceutical innovation trends [1] - Post-acquisition, approximately 23.1% of the company's combined revenue will come from outside China, providing a new growth engine for Eddycon's stable diagnostic business [1] Company Strategy - The acquisition represents a key milestone in Eddycon's development, expanding its business footprint across the entire healthcare value chain, from clinical testing to drug discovery and translational research [2] - Eddycon aims to become a trusted partner in the biopharmaceutical innovation and precision diagnostics sectors, leveraging Crown Bio's world-class CRO service capabilities [2] Financial Impact - The stable cash flow generated from Eddycon's Independent Clinical Laboratory (ICL) business will complement Crown Bio's high-margin CRO services, creating a more balanced and scalable business model [1]

Core Viewpoint - Aidi Kang Holdings (09860.HK) experienced a significant increase in stock price, opening over 7% higher and reaching a current price of 7.51 HKD, with a trading volume of 5.2683 million HKD [1] Summary by Category - **Stock Performance** - Aidi Kang Holdings opened with a rise of over 7% [1] - The current stock price is 7.51 HKD, reflecting a gain of 7.59% [1] - The trading volume recorded is 5.2683 million HKD [1]