格隆汇8月15日丨开拓药业-B(09939.HK)公布，董事会会议将于2025年8月28日（星期四）举行，藉以 （其中包括）考虑及批准本公司及其附属公司截至2025年6月30日止六个月的中期业绩及其发布。 ...

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示概不就因本公告全部或任何部份內容而產生或因 倚賴該等內容而引致的任何損失承擔任何責任。 開拓藥業有限公司 ＊ KINTOR PHARMACEUTICAL LIMITED ( 於開曼群島註冊成立的有限公司 ) KINTOR PHARMACEUTICAL LIMITED 董事會主席、執行董事及行政總裁 童友之博士 香港，2025 年 8 月 15 日 於本公告日期，執行董事為童友之博士 及倪翔博士 ；非執行董事為高維鵬先生及衛舸 琪女士；及獨立非執行董事為徐敏博士、楊懷嚴先生及童亮教授。 * 僅供識別 - 1 - ( 股份代號 : 9939) 董事會會議日期 開拓藥業有限公司*（「本公司」）董事（「董事」）會（「董事會」）謹此公佈， 董事會會議將於 2025 年 8 月 28 日（星期四）舉行，藉以（其中包括）考慮及批准本 公司及其附屬公司截至 2025 年 6 月 30 日止六個月之中期業績及其發佈。 承董事會命 ...

开拓药业-B(09939)发布公告，配售事项已于2025年8月5日根据协议的条款及条件完成，配售代理成功 配售合共2067.3万股配售股份予不少于六名承配人，配售价为每股配售股份2.08港元。据董事经作出一 切合理查询后所深知、尽悉及确信，承配人及彼等的最终实益拥有人均为独立于本公司或其关连人士且 与彼等概无关连的第三方。 由于完成认购事项的所有条件已达成，本公司已于2025年8月14日根据协议的条款及条件，按每股认购 股份2.08港元(与配售价相等)向卖方配发及发行2067.3万股认购股份。 ...

由于完成认购事项的所有条件已达成，公司已于2025年8月14日根据协议的条款及条件，按每股认购股 份2.08港元（与配售价相等）向卖方配发及发行20,673,000股认购股份。 格隆汇8月14日丨开拓药业-B(09939.HK)公布，配售事项已于2025年8月5日根据协议的条款及条件完 成，配售代理成功配售合共20,673,000股配售股份予不少于六名承配人，配售价为每股配售股份2.08港 元。 ...

Core Viewpoint - The company completed a placement of 20.673 million shares at a price of HKD 2.08 per share, with all conditions for the subscription being met [1] Group 1 - The placement was successfully executed by the placement agent to no fewer than six subscribers [1] - The subscribers and their ultimate beneficial owners are independent of the company and its related parties [1] - The company issued the subscription shares on August 14, 2025, at the same price as the placement [1]

表格類別： 股票 狀態： 新提交 公司名稱： 開拓藥業有限公司* 呈交日期： 2025年8月14日 如上市發行人的已發行股份或庫存股份出現變動而須根據《香港聯合交易所有限公司（「香港聯交所」）證券上市規則》(「《主板上市規則》」)第13.25A條 / 《香港聯合交易所有限公司GEM證券 上市規則》(「《GEM上市規則》」)第17.27A條作出披露，必須填妥第一章節 。 FF305 翌日披露報表 (股份發行人 ── 已發行股份或庫存股份變動、股份購回及/或在場内出售庫存股份) | 第一章節 | | | | | | | | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | | 於香港聯交所上市 | 是 | | | | 證券代號 (如上市) | 09939 | 說明 | | | | | | | | A. 已發行股份或庫存股份變動 | | | | | | | | | | | | | 已發行股份（不包括庫存股份）變動 | | 庫存股份變動 | | | | | 事件 | | 已發行股份（不包括庫 ...

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示概不就因本公告全部或任何部分內容而產生或因 倚賴該等內容而引致的任何損失承擔任何責任。 本公告或其任何副本概不得直接或間接在美國或在刊發或派發本公告屬違法的任何其他司 法權區刊發或派發。 本公告僅供參考，並不構成收購、購買或認購任何證券的邀請或要約。 本公告並不構成或組成在美國或在有關要約屬違法的任何其他司法權區購買或認購證券的 任何要約或招攬的一部分。本公告所述證券未曾亦不會根據經不時修訂1933年美國證券法（「美 國證券法」）或美國任何其他州證券法律登記，而且除非根據美國證券法登記或獲得美國證券 法登記規定的豁免或屬不受美國證券法登記規定約束的交易，否則不得在美國境內發售或出 售。本公司無意根據美國證券法登記本公告所述的任何證券或在美國公開發售證券。 開 拓 藥 業 有 限 公 司 * KINTOR PHARMACEUTICAL LIMITED （ 於 開 曼 群 島 註 冊 成 立 的 有 限 公 司 ） （股 份 代 號：9939） 完成先舊後新配售現有股份及 根據一般授權認購新股份 ...

Group 1: Market Overview - The Hang Seng Index rose by 1.88%, gaining 470 points to close at 25,439 points, while the Hang Seng Tech Index increased by 2.35% [1] - The early trading volume in the Hong Kong stock market reached HKD 143.8 billion [1] Group 2: Biotechnology Sector - The Hang Seng Biotechnology Index surged by 3.77%, driven by a collective rise in pharmaceutical stocks following the debut of the "dual directory" for drug applications [1] - Zhonghui Biotech-B (02627) saw a significant increase of 24%, while Jiuyuan Gene (02566) rose by 8.99%, and Kintor Pharmaceutical (09939) increased by 5.7% [1] - Innovent Biologics (01801) experienced a rise of 7.27%, and He Yu-B (02256) reached a new high with a 7.38% increase, reporting a 59% year-on-year growth in net profit for the first half of the year [1] Group 3: Pharmaceutical Developments - Daqi Pharmaceutical-B (06996) rose over 15% as Claudin 18.2 ADC was proposed for inclusion as a breakthrough therapy [2] Group 4: Technology Sector - Tencent's subsidiaries reported generally better-than-expected earnings, with Tencent Music-SW (01698) rising by 15%, and Reading Group (00772) also increasing by over 15% [2] - Weimeng Group (02013) saw an increase of over 7% [2] Group 5: Industrial and Manufacturing Sector - Chongqing Machinery (02722) rose by 8.9%, with an expected 50% year-on-year growth in net profit due to rapid growth in AIDC engine demand [3] - Zhongyan Hong Kong (06055) increased by over 7%, maintaining its position in the domestic cigarette export tax-free business, with earnings to be announced next Friday [3] Group 6: Technology and Electronics - Qiu Tai Technology (01478) rose by over 8%, reporting a 167% year-on-year increase in net profit for the first half of the year, leading to target price upgrades from multiple institutions [4] - Hong Teng Precision (06088) increased by over 9% post-earnings, with a cumulative rise of over 60% in the month, reporting an 11% revenue growth but a 3% decline in net profit [5] - Minmetals Resources (01208) rose by over 9% after reporting a 15-fold increase in net profit for the first half of the year and lowering cost guidance for its mines [6] Group 7: Performance Review - 361 Degrees (01361) fell by over 10% post-earnings, with institutions stating that the first half performance met expectations, but net profit growth was slightly lower than revenue growth [7]

Core Viewpoint - The company, Akeso Inc. (09939), experienced a stock price increase of over 3% during trading, closing at HKD 2.16 with a trading volume of HKD 8.0645 million, following the announcement of positive results from its Phase II clinical trial for the acne treatment compound GT20029 [1]. Group 1: Clinical Trial Results - The Phase II clinical trial for GT20029, a novel targeted androgen receptor (AR) protein degradation compound, successfully met its primary endpoint with statistically significant and clinically meaningful results [1]. - The efficacy, safety, and pharmacokinetic characteristics of GT20029 were reported to be excellent, with a recommended dosage for the Phase III clinical trial set at 0.5% [1]. - The trial was a multicenter, randomized, double-blind, placebo-controlled study conducted at 10 centers nationwide, led by Professor Xiang Leihong from Huashan Hospital affiliated with Fudan University [1].

Core Viewpoint - The company, 开拓药业-B, has seen a stock price increase of over 3% during trading, currently at 2.16 HKD, following the announcement of successful Phase II clinical trial results for its PROTAC compound GT20029 in treating acne [1] Company Summary - 开拓药业-B announced on August 12 that its self-developed PROTAC compound GT20029 has successfully met the primary endpoint in a Phase II clinical trial for acne treatment, showing statistical significance and clinical relevance [1] - The trial demonstrated excellent efficacy, safety, and pharmacokinetic characteristics, with a recommended dosage for the upcoming Phase III trial set at 0.5% [1] - The Phase II trial was a multicenter, randomized, double-blind, placebo-controlled study conducted at 10 centers nationwide, led by Professor 项蕾红 from Huashan Hospital affiliated with Fudan University [1] Industry Summary - The successful results of the Phase II clinical trial for GT20029 may indicate a positive trend in the dermatological treatment market, particularly for acne, which could attract further investment and interest in similar therapeutic developments [1]