10月15日，海普瑞盘中上涨2.16%，截至10:17，报11.81元/股，成交1928.86万元，换手率0.13%，总市 值173.29亿元。 资金流向方面，主力资金净流入5754.34元，大单买入187.13万元，占比9.70%，卖出186.56万元，占比 9.67%。 分红方面，海普瑞A股上市后累计派现42.10亿元。近三年，累计派现5.14亿元。 机构持仓方面，截止2025年6月30日，海普瑞十大流通股东中，香港中央结算有限公司位居第八大流通 股东，持股1131.76万股，相比上期增加637.65万股。创新药（159992）退出十大流通股东之列。 责任编辑：小浪快报 资料显示，深圳市海普瑞药业集团股份有限公司位于广东省深圳市南山区松坪山郎山路21号,香港湾仔 港湾道30号新鸿基中心47楼4724室，成立日期1998年4月21日，上市日期2010年5月6日，公司主营业务 涉及肝素钠原料药、下游低分子肝素产品的研究、生产和销售。主营业务收入构成为：制剂63.06%， CDMO18.59%，肝素钠以及低分子肝素钠原料药16.05%，其他2.30%。 海普瑞所属申万行业为：医药生物-化学制药-化学制剂。所属概 ...

2、赛湾生物具备向客户提供mRNA疫苗开发及生产CDMO服务的能力。赛湾生物凭借优秀的工艺开 发、准时交付以及成功的运营能力，继续推进mRNA疫苗供应链的工作，支持全球多个已商业化的 mRNA疫苗的生产。 3、深圳市海普瑞药业集团股份有限公司的主营业务是肝素产业链，生物大分子CDMO和创新药物的投 资，开发及商业化。 4、根据2024年年报，公司海外营收占比为93.04%，受益于人民币贬值。 (免责声明：分析内容来源于互联网，不构成投资建议，请投资者根据不同行情独立判断) 来源：新浪证券-红岸工作室 10月14日，海普瑞跌1.53%，成交额5958.26万元，换手率0.41%，总市值169.62亿元。 异动分析 创新药+生物疫苗+CRO概念+人民币贬值受益 1、2024年年报，海普瑞于 1998 年成立于深圳，是拥有 A+H 双融资平台的领先跨国制药企业，主要业 务覆盖肝素产业链、生物大分子 CDMO 和创新药物的投资、开发及商业化，致力于为全球患者带去高 质量的安全有效药物和服务，护佑健康。 技术面：筹码平均交易成本为11.57元 该股筹码平均交易成本为11.57元，近期筹码减仓，但减仓程度减缓；目前股价在 ...

Core Viewpoint - The company Haiprui experienced a decline of 1.68% in stock price, with a trading volume of 47.80 million yuan and a total market capitalization of 17.23 billion yuan [1] Company Overview - Haiprui, established in 1998 in Shenzhen, is a leading multinational pharmaceutical company with A+H dual financing platforms, focusing on the heparin industry chain, biopharmaceutical CDMO, and innovative drug investment, development, and commercialization [2][7] - The main business revenue composition includes formulations (63.06%), CDMO (18.59%), heparin sodium and low molecular weight heparin raw materials (16.05%), and others (2.30%) [7] Financial Performance - For the first half of 2025, Haiprui reported a revenue of 2.82 billion yuan, a year-on-year decrease of 0.71%, and a net profit attributable to shareholders of 422 million yuan, down 36.44% year-on-year [7] - The company has distributed a total of 4.21 billion yuan in dividends since its A-share listing, with 514 million yuan distributed over the past three years [8] Market Position and Trends - As of the 2024 annual report, overseas revenue accounted for 93.04% of total revenue, benefiting from the depreciation of the yuan [3] - The company operates in the pharmaceutical and biotechnology sector, specifically in chemical pharmaceuticals and chemical preparations, with concepts including raw materials, heparin, biopharmaceuticals, innovative drugs, and vaccines [7] Institutional Holdings - As of June 30, 2025, the eighth largest circulating shareholder is Hong Kong Central Clearing Limited, holding 11.32 million shares, an increase of 6.38 million shares from the previous period [9]

FF301 致：香港交易及結算所有限公司 公司名稱: 深圳市海普瑞藥業集團股份有限公司 呈交日期: 2025年10月3日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | H | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 09989 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 220,094,500 | RMB | | 1 RMB | | 220,094,500 | | 增加 / 減少 (-) | | | | | | RMB | | | | 本月底結存 | | | 220,094,500 | RMB | | 1 RMB | | 220,094,500 | | 2. 股份分類 | 普通股 | 股份類別 | A | | 於香港聯交所上市 (註1) | | 否 | | | --- | --- | --- | --- | --- | --- ...

Core Viewpoint - The company, Shenzhen Hepalink Pharmaceutical Group Co., Ltd., is a leading multinational pharmaceutical enterprise with a focus on heparin, biopharmaceutical CDMO, and innovative drug development, benefiting from the depreciation of the RMB and a strong overseas revenue stream [2][3]. Company Overview - Established in 1998 and listed in 2010, Hepalink operates primarily in the heparin industry, with its main business segments including formulations (63.06%), CDMO (18.59%), and heparin raw materials (16.05%) [7]. - As of June 30, 2025, the company reported a revenue of 2.817 billion yuan, a year-on-year decrease of 0.71%, and a net profit of 422 million yuan, down 36.44% year-on-year [7]. Financial Performance - The company’s overseas revenue accounted for 93.04% of total revenue, benefiting from the depreciation of the RMB [3]. - The total market capitalization of Hepalink is 17.666 billion yuan, with a trading volume of 37.9727 million yuan on September 25, 2023 [1]. Shareholder Information - As of June 30, 2025, the number of shareholders decreased by 7.29% to 26,300, with the average circulating shares per person remaining at zero [7]. - The company has distributed a total of 4.21 billion yuan in dividends since its A-share listing, with 514 million yuan distributed over the past three years [8]. Market Activity - On September 25, 2023, the stock price of Hepalink fell by 1.15%, with a turnover rate of 0.25% [1]. - The stock is currently near a resistance level of 12.33 yuan, with an average trading cost of 11.57 yuan [6].

Core Viewpoint - The recent trading activity and financial performance of Haiprui Pharmaceutical indicate a mixed outlook, with notable fluctuations in financing and stockholder dynamics [1][2]. Financing Activity - On September 24, Haiprui's stock rose by 1.16%, with a trading volume of 41.77 million yuan. The financing buy-in amounted to 4.87 million yuan, while the financing repayment was 5.70 million yuan, resulting in a net financing outflow of 0.83 million yuan [1]. - As of September 24, the total financing and securities lending balance for Haiprui was 258 million yuan, with the financing balance of 256 million yuan accounting for 1.69% of the circulating market value, which is above the 60th percentile of the past year [1]. - In terms of securities lending, Haiprui repaid 6,200 shares and sold 8,500 shares on the same day, with a selling amount of 0.1035 million yuan. The remaining securities lending volume was 10,840 shares, with a balance of 1.32 million yuan, exceeding the 90th percentile of the past year [1]. Financial Performance - For the first half of 2025, Haiprui reported a revenue of 2.817 billion yuan, reflecting a year-on-year decrease of 0.71%. The net profit attributable to shareholders was 422 million yuan, down 36.44% year-on-year [2]. - Since its A-share listing, Haiprui has distributed a total of 4.21 billion yuan in dividends, with 514 million yuan distributed over the past three years [2]. Shareholder Dynamics - As of June 30, 2025, Haiprui had 26,300 shareholders, a decrease of 7.29% from the previous period. The average circulating shares per shareholder remained at 0 [2]. - Among the top ten circulating shareholders, Hong Kong Central Clearing Limited ranked as the eighth largest, holding 11.32 million shares, an increase of 6.38 million shares from the previous period [2].

Core Viewpoint - The company, Haiprui, is a leading multinational pharmaceutical enterprise with a focus on the heparin industry chain, biopharmaceutical CDMO, and innovative drug development, benefiting from the depreciation of the RMB and a significant overseas revenue share [2][3]. Company Overview - Haiprui was established in 1998 in Shenzhen and has both A and H share financing platforms [2]. - The main business segments include heparin sodium raw materials, downstream low molecular weight heparin products, and CDMO services for biopharmaceuticals [7]. - As of June 30, 2025, Haiprui reported a revenue of 2.817 billion yuan, a year-on-year decrease of 0.71%, and a net profit of 422 million yuan, down 36.44% year-on-year [7]. Financial Performance - The company’s overseas revenue accounted for 93.04% of total revenue, benefiting from the depreciation of the RMB [3]. - The revenue composition includes 63.06% from formulations, 18.59% from CDMO, 16.05% from heparin sodium and low molecular weight heparin raw materials, and 2.30% from other sources [7]. - Cumulative cash dividends since the A-share listing amount to 4.21 billion yuan, with 514 million yuan distributed over the past three years [8]. Market Activity - On September 22, Haiprui's stock price fell by 0.81%, with a trading volume of 45.2628 million yuan and a market capitalization of 18.062 billion yuan [1]. - The stock has seen a net outflow of 3.1095 million yuan from major funds today, indicating a reduction in holdings over the past three days [4][5]. Technical Analysis - The average trading cost of the stock is 11.56 yuan, with the current price approaching a resistance level of 12.33 yuan, suggesting potential for a price correction if this level is not surpassed [6].

Core Viewpoint - The article discusses the performance and business operations of Shenzhen Hepalink Pharmaceutical Group Co., Ltd., highlighting its focus on heparin, biopharmaceuticals, and innovative drugs, as well as the impact of RMB depreciation on its overseas revenue. Company Overview - Shenzhen Hepalink Pharmaceutical Group Co., Ltd. was established in 1998 and is a leading multinational pharmaceutical company with A+H dual financing platforms, primarily engaged in the heparin industry chain, biopharmaceutical CDMO, and innovative drug investment, development, and commercialization [2][7] - The company's main business revenue composition includes: formulations (63.06%), CDMO (18.59%), heparin sodium and low molecular weight heparin raw materials (16.05%), and others (2.30%) [7] Financial Performance - For the first half of 2025, the company achieved operating revenue of 2.817 billion yuan, a year-on-year decrease of 0.71%, and a net profit attributable to shareholders of 422 million yuan, a year-on-year decrease of 36.44% [7] - As of June 30, 2025, the company's overseas revenue accounted for 93.04%, benefiting from the depreciation of the RMB [3] Market Activity - On September 19, the company's stock price fell by 0.72%, with a trading volume of 55.9683 million yuan and a turnover rate of 0.36%, resulting in a total market capitalization of 18.209 billion yuan [1] - The stock has seen a net outflow of 9.4339 million yuan from main funds today, with a continuous three-day reduction in main fund positions [4][5] Technical Analysis - The average trading cost of the stock is 11.56 yuan, with recent chip reduction slowing down; the current stock price is near a resistance level of 12.64 yuan, indicating potential for a pullback if this level is not surpassed [6]

(A joint stock company incorporated in the People's Republic of China with limited liability) （於中華人民共和國註冊成立的股份有限公司） Stock Code 股份代號 : 9989 Interim Report 中期報告 2025 | 管理層討論與分析 | | | --- | --- | | Corporate Governance and Other Information Disclosed | 22 | | 企業管治及其他披露資料 | | | Interim Condensed Consolidated Statements of Profit or Loss | 36 | | 中期簡明綜合損益表 | | | Interim Condensed Consolidated Statements of Comprehensive Income | 37 | | 中期簡明綜合全面收益表 | | | Interim Condensed Consolidated Statements of Financial Posi ...

Core Insights - The article highlights the changes in the Hong Kong Stock Connect holdings, with notable increases and decreases in ownership percentages for various companies [1][2]. Group 1: Increased Holdings - Heng Rui Medicine (01276) saw the largest increase in ownership percentage, rising by 1.49% to a total of 13.84% [2]. - Kanglong Chemical (03759) experienced a 1.35% increase, bringing its ownership to 60.51% [2]. - Zhaoyan New Drug (06127) increased by 1.27%, reaching a holding of 43.70% [2]. - Other companies with significant increases include Junshi Biosciences (01877) at +1.24% (59.08%) and China Pacific Insurance (02601) at +1.20% (44.16%) [2]. Group 2: Decreased Holdings - Shandong Molong (00568) had the largest decrease, with a drop of 1.99% to 57.67% [2]. - Yisou Technology (02550) decreased by 0.99%, now holding 37.95% [2]. - Nanjing Panda Electronics (00553) saw a reduction of 0.98%, bringing its ownership to 42.65% [2]. - Other notable decreases include Kailai Ying (06821) at -0.95% (43.35%) and Meizhong Jiahe (02453) at -0.95% (32.06%) [2]. Group 3: Five-Day Changes - In the last five trading days, China Merchants Energy (01138) had the highest increase in ownership, up by 6.19% to 65.63% [3]. - Shandong Molong (00568) also saw a significant increase of 3.74% [3]. - Other companies with notable increases include Zhongchu Innovation (03931) at +3.62% (10.35%) and Youbao Online (02429) at +3.33% (17.38%) [3]. Group 4: Twenty-Day Changes - Over the past twenty days, Anjiren Food (02648) experienced the largest increase, up by 12.29% to 20.54% [4]. - China Merchants Energy (01138) also saw a significant increase of 9.07% [4]. - Other companies with notable increases include Yimai Sunshine (02522) at +7.70% (43.02%) and Lens Technology (06613) at +7.56% (13.64%) [4].