Market Performance - The Hong Kong stock market indices continued to rise, with the Hang Seng Index up 1.23% to 25,077.62 points, the Tech Index up 4.06% to 5,674.31 points, and the China Enterprises Index up 0.73% to 8,947.79 points [2] - The Hang Seng Index has seen a cumulative increase of over 13% since its rise began in May, despite a volatile performance in August [3] Reasons for Underperformance - Compared to A-shares, the Hang Seng Index's performance has lagged, with the Shanghai Composite and ChiNext rising 7.97% and 15.32% respectively [5] - Key reasons for the underperformance include: - Liquidity issues, with the Hibor rate rising sharply from near zero to nearly 3%, tightening liquidity in the Hong Kong banking sector [5] - Continuous downward revisions in earnings forecasts, with the 2025 earnings expectation for the Hang Seng Index down to -1.4% and nearly 60% of constituent stocks facing earnings downgrades [5] - A decline in the AH premium below 125%, reducing the attractiveness of Hong Kong stocks for dividend-seeking investors [5] Notable Stock Performances - Dongfeng Motor Group (00489.HK) led the market with an 88.04% increase, attributed to its subsidiary Lantu Motors' upcoming listing and the company's privatization [6] - LiJin Technology (00558.HK) rose 69.94% after signing strategic cooperation agreements for a magnesium alloy humanoid robot project [6] - Rongchang Bio (09995.HK) increased by 62.77% following positive clinical trial results for its core product [6] - Gold stocks like Lingbao Gold (03330.HK) and China Gold International (02099.HK) saw increases of 15.46% and 61.48% respectively, benefiting from rising international gold prices [6] Sector Highlights - Cryptocurrency stocks performed well, with notable increases in Guotai Junan International (01788.HK) and Huajian Medical (01931.HK) [8][9] - Pharmaceutical stocks gained attention, with WuXi Biologics (02269.HK) and WuXi AppTec (02359.HK) rising 6.96% and 6.52% respectively [10][11] - Gold stocks were boosted by favorable market conditions, with Lingbao Gold and others seeing significant gains [12][13] - Lithium battery stocks benefited from supply concerns and industry signals aimed at reducing competition, with TianNeng Power (00819.HK) rising 10.79% [14][15] Weak Performances - The film and entertainment sector saw declines, with major players like DaMai Entertainment (01060.HK) and Huayi Brothers (5.48.HK) experiencing significant drops [18][19] - Shipping stocks also performed poorly, with COSCO Shipping Holdings (01919.HK) reporting a decrease in profits amid weak demand [20] Individual Stock Movements - ZhiZi Cheng Technology (09911.HK) surged nearly 20% after reporting a 40% increase in revenue for the first half of the year [22][23] - China Nonferrous Mining (01258.HK) rose 8.37% with a 20.2% increase in net profit despite a revenue decline [24]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並表明概不就因本公告全部或任何部份內容而產生或因依賴該等 內容而引致的任何損失承擔任何責任。 RemeGen Co., Ltd.* 榮 昌 生 物 製 藥（ 煙 台 ）股 份 有 限 公 司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：9995） 董事會宣佈，於2025年8月29日，本公司與浦發銀行煙台分行訂立浦發銀行理 財產品協議，據此本公司同意以人民幣300.0百萬元的閒置自有資金向浦發銀行 煙台分行購買理財產品。 上市規則的涵義 由於本公司在2025年7月與浦發銀行訂立了另外兩份其他理財產品協議且仍然 持有該等協議項下的理財產品，因此該等理財產品協議及浦發銀行理財產品協 議項下擬進行的各項交易均在12個月內與同一家銀行進行且性質相似，就根據 上市規則第14.22條計算相關百分比率而言，該等交易在各情況下將合併處理， 猶如該等交易為與該銀行進行的一次交易。 根據上市規則第14.07條（按與前述兩份其他理財產品協議合併基準）計算的浦發 銀行理財產品協議之適用百分比率有一項超過5%，但所有 ...

Group 1 - Pharmaceutical stocks showed strong performance today, with notable increases in share prices for companies such as Heptares Therapeutics-B (up 16.3% to HKD 14.77), Rongchang Biopharmaceutical (up 12.5% to HKD 99), and Kintor Pharmaceutical-B (up 11.92% to HKD 22.34) [1] - Upcoming major events include the World Lung Cancer Conference (WCLC) in September and the European Society for Medical Oncology (ESMO) in October, where several innovative domestic drug research results will be presented, including AK112 from Kangfang Biopharmaceutical and DB-1311 from Ying'en Biopharmaceutical [1] - Several Chinese pharmaceutical companies have announced significant patent licensing transactions since August, including Rongchang Biopharmaceutical's agreement with Santen Pharmaceutical for RC28-E injection, involving an upfront payment of CNY 250 million, potential milestone payments of up to CNY 520 million, and sales milestone payments of up to CNY 525 million [1] Group 2 - Guoyuan Securities noted that as the mid-year report season concludes, the market is shifting focus towards new directions, particularly in innovative drugs, overseas expansion, and the clearing of centralized procurement [2] - The innovative drug sector in China is entering a stage of result realization, with many research and development catalysts expected to drive growth, unaffected by trade wars, making it a key investment theme for the pharmaceutical sector in 2025 [2] - Some innovative drug stocks have seen significant price increases, and it is recommended to pay attention to those with research and development catalysts that have previously lagged in stock performance [2]

Group 1 - Pharmaceutical stocks showed strong performance today, with notable increases in share prices for companies such as Heptares Therapeutics-B (up 16.3% to HKD 14.77), Rongchang Biopharmaceutical (up 12.5% to HKD 99), and Kintor Pharmaceutical-B (up 11.92% to HKD 22.34) [1] - Upcoming major conferences, including the 2025 World Lung Cancer Conference (WCLC) and the European Society for Medical Oncology (ESMO) annual meeting, will showcase research results from various domestic innovative drugs, such as AK112 from Kangfang Biopharmaceutical and DB-1311 from Ying'en Biopharmaceutical [1] - Several Chinese pharmaceutical companies have announced significant patent licensing transactions since August, including Rongchang Biopharmaceutical's agreement with Santen Pharmaceutical regarding RC28-E injection, which involves an upfront payment of CNY 250 million, potential milestone payments of up to CNY 520 million, and sales milestone payments of up to CNY 525 million [1] Group 2 - Guoyuan Securities noted that as the interim report season comes to a close, the market is shifting focus towards new directions, particularly in innovative drugs, overseas expansion, and the clearing of centralized procurement [2] - The innovative drug sector in China is entering a stage of result realization, with many research advancements expected to catalyze growth, unaffected by trade wars, making it a key investment theme for the pharmaceutical sector in 2025 [2] - Some innovative drug stocks have seen significant price increases, and it is recommended to monitor stocks with research catalysts that have previously lagged in price performance [2]

Group 1 - The A-share biopharmaceutical sector experienced a significant surge in the afternoon of August 29, with Rongchang Biopharmaceutical rising over 12% [2] - Maiwei Biopharmaceutical saw a sharp increase of 9% [2] - Kangchen Pharmaceutical previously hit the daily limit, while Sanofi and Wanzhe shares, as well as Sanyuan Gene, all rose over 6% [2]

Group 1 - The biopharmaceutical ETF (159859) has shown strong performance, rising 1.16% with a trading volume exceeding 94 million yuan, making it the top performer among its peers [1] - The ETF has seen a net inflow of over 61 million yuan over the past three trading days, indicating strong investor interest [1] - The ETF closely tracks the National Index of Biopharmaceuticals (399441.SZ), which covers various sectors including innovative drugs, CXO, vaccines, and blood products [1] Group 2 - The innovative drug ETF Tianhong (517380) is the largest in the market, covering both A-shares and Hong Kong stocks, and is the only ETF tracking the Hang Seng-Hushen-Hong Kong Innovative Drug Selected 50 Index [2] - The Tianhong ETF has also experienced a net inflow of over 64 million yuan over the past three trading days, reflecting positive market sentiment [2] - A recent meeting emphasized the need for comprehensive reforms in drug regulation and innovation, which could positively impact the pharmaceutical industry [2] Group 3 - Overall, the market may face short-term fluctuations, but there are signs of capital rotation, with many undervalued stocks beginning to rebound [3] - The expectation of interest rate cuts and economic recovery may lead to a focus on cyclical sectors in the future [3]

Core Viewpoint - Rongchang Biologics (09995) has seen a nearly 9% increase in stock price, reaching HKD 95.95, with a trading volume of HKD 383 million, following the release of its interim performance report [1] Financial Performance - For the first half of the year, the company reported a revenue of CNY 1.09 billion, representing a year-on-year growth of 48% [1] - The net profit attributable to shareholders was a loss of CNY 450 million, which is a reduction in loss by CNY 330 million compared to the previous year [1] Product Performance - The revenue growth is primarily attributed to the continuous increase in sales of its core products, Taitasip and Vidisizumab, both of which were included in the medical insurance catalog in 2021 [1] - According to Zhongjin Securities, the company's performance in the first half of the year met expectations, with Taitasip's gMG already approved for market launch [1] - The company anticipates submitting applications for market approval for pSS and IgAN in the second half of 2025 [1] - Vidisizumab has been approved for treating second-line HER2-positive breast cancer with liver metastasis, and applications for second-line HER2-low expressing breast cancer and first-line urothelial carcinoma have been submitted [1] - The continuous expansion of indications for core products is expected to accelerate commercialization [1]

Core Insights - Rongchang Biopharma (09995) shares increased by approximately 9%, reaching HKD 95.95 with a trading volume of HKD 383 million [1] Financial Performance - For the first half of the year, the company reported revenue of CNY 1.09 billion, representing a year-on-year growth of 48% [1] - The net loss attributable to shareholders was CNY 450 million, which is a reduction in loss by CNY 330 million compared to the previous year [1] Product Performance - The revenue growth is primarily driven by increased sales of its core products, Tai Taisip and Vidi Sima, both of which were included in the medical insurance directory in 2021 [1] - The approval of Tai Taisip for gMG has been granted, with expectations for pSS and IgAN to submit for market approval in the second half of 2025 [1] - Vidi Sima has received approval for treating second-line HER2-positive breast cancer with liver metastasis, and applications for additional indications are underway, which is expected to accelerate commercialization [1]

Group 1 - The company reported a revenue of 1.1 billion yuan (+48%) for the first half of 2025, with a net loss attributable to shareholders of 450 million yuan, meeting expectations [1] - Core products are experiencing continuous growth, with over 1,000 hospitals approved for both autoimmune and oncology treatments. The commercialization team for autoimmune diseases has approximately 900 members, while the oncology team has over 500 members [1] - The company successfully licensed Tai'tasip for the treatment of myasthenia gravis to Vor Bio, receiving an upfront payment of 45 million USD and potential milestone payments totaling up to 4.105 billion USD [2] Group 2 - The company licensed RC28 to Santen China, receiving an upfront payment of 250 million yuan and potential milestone payments totaling up to 525 million yuan [3] - The company expects revenues of 2.21 billion, 2.95 billion, and 4.26 billion yuan for the years 2025, 2026, and 2027, respectively, driven by the continued growth of Tai'tasip and Vidi'simab [3]

Core Viewpoint - The company reported a revenue of 1.09 billion yuan for the first half of 2025, representing a year-on-year growth of 48%, while the net loss attributable to shareholders was 450 million yuan, a reduction in loss by 330 million yuan compared to the previous year, aligning with expectations [1] Group 1: Financial Performance - The company's gross margin reached 84.0% in the first half of 2025, an increase of 5.8 percentage points compared to the same period in 2024 [1] - The sales expense ratio was 47.9%, a decrease of 4.6 percentage points year-on-year, indicating effective cost and expense management [1] - The company reduced its losses by 42.4% year-on-year and by 23.2% quarter-on-quarter in the second quarter of 2025 [1] Group 2: Product Development and Market Potential - The core product, Tai Tasi Pu (泰它西普), has been approved for market launch, with expectations for pSS and IgAN to submit applications in the second half of 2025 [1] - The company has received approval for the use of Vidi Xi Tuo (维迪西妥单抗) in treating second-line HER2-positive breast cancer with liver metastasis, and has submitted applications for other indications [1] - The PD-1/VEGF dual antibody is advancing in global clinical research, with a focus on its potential for international expansion [2] Group 3: Clinical Trials and Regulatory Approvals - Tai Tasi Pu has reached the primary endpoint in the Phase III clinical trial for IgA nephropathy in China, with plans to expedite the application for market approval [2] - The trial included 318 adult patients receiving standard treatment, showing a 55% reduction in the urine protein-to-creatinine ratio after 39 weeks of treatment [2] Group 4: Profit Forecast and Valuation - Based on the semi-annual report and expected potential collaboration funds, the profit forecast for 2025/2026 has been adjusted from a loss of 915 million yuan/333 million yuan to a loss of 345 million yuan and a profit of 34 million yuan, respectively [3] - The target price has been raised by 10.6% to 105.44 HKD, indicating a 20% upside potential from the current stock price [3]