证券代码：000710 证券简称：贝瑞基因 公告编号：2025-046 成都市贝瑞和康基因技术股份有限公司 关于为全资子公司提供担保的进展公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 一、担保审批情况概述 成都市贝瑞和康基因技术股份有限公司（以下简称"贝瑞基因""公司"） 于 2025 年 8 月 20 日召开第十届董事会第十六次会议审议通过了《关于为全资 子公司提供担保的议案》。公司之全资子公司杭州贝瑞和康基因诊断技术有限 公司（以下简称"杭州贝瑞"）向杭州联合农村商业银行股份有限公司高沙支 行（以下简称"杭州联合银行高沙支行"）申请综合授信 4,000 万元，授信期 限 1 年。公司同意为杭州贝瑞使用上述授信所形成的债务提供连带责任保证担 保。具体内容详见公司于 2025 年 8 月 21 日在巨潮资讯网上披露的《关于为全 资子公司提供担保的公告》（公告编号：2025-042）。 5、法定代表人：高扬 6、注册资本：11,500 万元人民币 7、注册地点：浙江省杭州经济技术开发区白杨街道 6 号大街 260 号 9 幢,16 幢一层、二层 8、经营 ...

成都市贝瑞和康基因技术股份有限公司 2025 年半年度报告全文 成都市贝瑞和康基因技术股份有限公司 2025 年半年度报告 2025 年 8 月 1 所有董事均已出席了审议本次半年报的董事会会议。 本报告中涉及的未来计划等前瞻性陈述，不构成公司对投资者的实质承诺， 投资者及相关人士均应当对此保持足够的风险认识，并且应当理解计划、预 测与承诺之间的差异。 公司在本报告第三节"管理层讨论与分析"之"十、公司面临的风险和应 对措施"中描述了公司未来经营中可能面对的风险，敬请广大投资者注意阅 读。 公司计划不派发现金红利，不送红股，不以公积金转增股本。 2 | | | 成都市贝瑞和康基因技术股份有限公司 2025 年半年度报告全文 第一节 重要提示、目录和释义 公司董事会、监事会及董事、监事、高级管理人员保证半年度报告内容 的真实、准确、完整，不存在虚假记载、误导性陈述或者重大遗漏，并承担 个别和连带的法律责任。 公司负责人高扬、主管会计工作负责人王冬及会计机构负责人(会计主管 人员)高莉声明：保证本半年度报告中财务报告的真实、准确、完整。 | 第二节 | 公司简介和主要财务指标 6 | | --- | --- | ...

Investment Rating - The report initiates coverage with a "Buy" rating for the company [3][4]. Core Insights - The company focuses on reproductive health and genetic disease testing, providing a comprehensive solution of "products + services" and is a leading player in the domestic genetic testing field [1][15]. - The market for life science sequencing solutions in China is expected to grow at a compound annual growth rate (CAGR) of 14.9% from 2018 to 2023, reaching 138.8 billion yuan by 2033, indicating potential for the company's continued market penetration [1]. - The company is leveraging its data and technology to build competitive barriers in the AI healthcare industry, with the AI medical market projected to reach 11.43 billion yuan by 2025 and 28.61 billion yuan by 2027 [2]. Summary by Sections Company Overview and Business Layout - The company, established in 2010 and listed in 2017, began with non-invasive prenatal testing (NIPT) and has expanded into genetic disease testing and research services [15]. - It utilizes high-throughput sequencing and third-generation HiFi sequencing technologies to provide genetic testing services and related equipment, reagents, and software [15]. Industry Development and Core Business - The company’s core business includes high-throughput sequencing technology and third-generation sequencing services, focusing on reproductive health and genetic disease testing [40]. - The company has established a comprehensive service model for hospitals and third-party laboratories, integrating advanced sequencing technology with AI applications [40]. Financial Performance and Forecast - The company’s revenue is projected to be 1.05 billion yuan in 2025, with a gradual increase to 1.42 billion yuan by 2027, while net profit is expected to improve from a loss of 140 million yuan in 2025 to a profit of 400 million yuan in 2027 [3][4]. - The company’s gross margin has shown an upward trend, increasing from 42.72% in 2022 to 46.86% in 2024, driven by a higher proportion of reagent sales [29]. AI Medical Sector - The company is positioned to capitalize on the AI medical sector, with its GENOisi™ intelligent model facilitating a smart data management and clinical decision-making process [2][20]. - The AI medical market is rapidly expanding, supported by favorable domestic policies, and the company aims to leverage its extensive clinical data and self-developed algorithms for commercial applications [2].

Group 1 - The stock price of Berry Genomics closed at 15.94 yuan on August 26, 2025, down 4.03% from the previous trading day, with a trading volume of 977 million yuan [1] - Berry Genomics operates in the medical device, AI pharmaceutical, and assisted reproduction sectors, focusing on the research and application of gene sequencing technology [2] - The company's subsidiary, Hangzhou Berry Health and Technology Co., Ltd., recently received a medical device registration certificate from the National Medical Products Administration for its NovaSeq6000Dx-CN-BG gene sequencer, which meets various gene testing needs for the prevention of birth defects [2] Group 2 - On August 26, 2025, the main capital outflow for Berry Genomics was 193 million yuan, accounting for 3.71% of its circulating market value [2] - Over the past five days, the main capital inflow was 261 million yuan, representing 5.01% of its circulating market value [2]

证券代码：000710 证券简称：贝瑞基因 公告编号：2025-044 成都市贝瑞和康基因技术股份有限公司 关于全资子公司基因测序仪获得医疗器械注册证的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有 虚假记载、误导性陈述或重大遗漏。 成都市贝瑞和康基因技术股份有限公司（以下简称"公司"）全资子公司杭 州贝瑞和康基因诊断技术有限公司的NovaSeq™ 6000Dx-CN-BG基因测序仪于近日 正式获得国家药品监督管理局（NMPA）颁发的医疗器械注册证（注册证编号：国 械注准20253221734）。现将具体情况公告如下： | 产品名称 | 基因测序仪 | | --- | --- | | 注册人名称 | 杭州贝瑞和康基因诊断技术有限公司 | | 注册证编号 | 国械注准20253221734 | | 型号及规格 | NovaSeqTM 6000Dx-CN-BG | | 有效期 | 2025年8月25日至2030年8月24日 | | 结构及组成 | 产品功能上由移液模块，光学模块，数据处理模块和触屏显示控制部分组成。 结构上由一个触摸显示器，一个状态显示区，一个测序芯片室和一个试剂存 | | ...

Core Viewpoint - Berry Genomics (000710) announced that its wholly-owned subsidiary, Hangzhou Berry Genomics and Health Technology Co., Ltd., has recently received a medical device registration certificate from the National Medical Products Administration for its NovaSeq6000Dx-CN-BG gene sequencer, which can meet various genetic testing needs for the three-level prevention of birth defects [1] Company Summary - The NovaSeq6000Dx-CN-BG high-throughput sequencer is designed to fulfill the genetic testing requirements related to the prevention of birth defects [1]

Core Viewpoint - Berry Genomics' subsidiary has received a medical device registration certificate for its NovaSeq™6000Dx-CN-BG gene sequencer, indicating a significant advancement in the company's product offerings in the field of DNA sequencing [1]. Company Summary - Berry Genomics announced that its wholly-owned subsidiary, Hangzhou Berry Genomics Technology Co., Ltd., has obtained a medical device registration certificate from the National Medical Products Administration for the NovaSeq™6000Dx-CN-BG gene sequencer [1]. - The NovaSeq™6000Dx-CN-BG utilizes reversible terminator sequencing technology, which is clinically applied for human deoxyribonucleic acid (DNA) sequencing [1].

Market Overview - On August 26, the AI medical sector experienced a slight decline of 0.01%, with Bei Rui Gene leading the losses [1] - The Shanghai Composite Index closed at 3868.38, down 0.39%, while the Shenzhen Component Index closed at 12473.17, up 0.26% [1] Stock Performance - Notable gainers in the AI medical sector included: - Saily Medical (603716) with a closing price of 36.40, up 4.99% and a trading volume of 707,500 shares, totaling 2.592 billion yuan [1] - Sichuang Medical (300078) closed at 3.80, up 2.98% with a trading volume of 666,200 shares, totaling 250 million yuan [1] - Jiahe Meikang (688246) closed at 38.21, up 2.00% with a trading volume of 56,600 shares, totaling 215 million yuan [1] - Major decliners included: - Bei Rui Gene (000710) closed at 15.94, down 4.03% with a trading volume of 609,700 shares, totaling 977 million yuan [2] - Yao Shi Technology (300725) closed at 45.18, down 3.91% with a trading volume of 165,300 shares, totaling 756 million yuan [2] - Anbiping (688393) closed at 31.66, down 3.21% with a trading volume of 40,200 shares, totaling 129 million yuan [2] Capital Flow - The AI medical sector saw a net outflow of 707 million yuan from institutional investors, while retail investors experienced a net inflow of 697 million yuan [2] - The table of capital flow indicates that: - Wei Ning Health (300253) had a net inflow of 75.39 million yuan from institutional investors [3] - Zhejiang Data Culture (600633) had a net inflow of 67.70 million yuan from institutional investors [3] - Huada Gene (300676) had a net inflow of 23.14 million yuan from institutional investors [3]

Core Viewpoint - The collaboration between Chengdu Berry Genomics Co., Ltd. and its partners aims to drive innovation in medical technology and industry upgrades through digital assetization, exploring RWA applications to reshape the global gene diagnostic asset value chain and maximize asset value [1][2]. Group 1: Company Overview - Berry Genomics focuses on technological innovation to advance precision medicine, utilizing high-throughput sequencing technology to create solutions across various fields, including reproductive health and genetic disease testing [2]. - The company has pioneered the clinical transformation of third-generation HiFi sequencing technology and has successfully launched multiple products, establishing a strong technological moat [2]. Group 2: Collaboration Details - The partners plan to use the stable revenue from Berry Genomics' third-generation HiFi sequencing production line and the technical service income from the GENOisi™ intelligent system as underlying assets for digital rights exploration and RWA tokenization [4]. - The project aims to quantify the value of the GENOisi™ intelligent system as a new type of digital asset, accelerating the integration of technology and capital, thereby injecting new momentum into the sustainable development of precision medicine [4]. Group 3: Future Directions - This collaboration represents a critical step in the digitalization of healthcare assets, standardizing data rights in the medical health sector and enhancing the quantification and circulation of new digital assets like AI intelligent systems [5]. - The company intends to deepen technical and resource collaboration with partners, actively exploring more digital paths for medical assets, contributing to the popularization of precision medicine, data value extraction, and the upgrade of the global healthcare ecosystem [5].

Market Performance - On August 22, the medical services sector rose by 1.29%, with Berry Genomics leading the gains [1] - The Shanghai Composite Index closed at 3825.76, up 1.45%, while the Shenzhen Component Index closed at 12166.06, up 2.07% [1] Top Gainers in Medical Services - Berry Genomics (000710) closed at 15.79, up 10.03% with a trading volume of 749,900 shares and a turnover of 1.153 billion yuan [1] - Haochen Medical (002622) closed at 4.21, up 9.92% with a trading volume of 1.4424 million shares and a turnover of 585 million yuan [1] - Golden Domain Medical (603882) closed at 11, up 4.02% with a trading volume of 148,600 shares and a turnover of 461 million yuan [1] Top Losers in Medical Services - Boji Pharmaceutical (300404) closed at 11.37, down 5.09% with a trading volume of 490,800 shares and a turnover of 557 million yuan [2] - ST Shenghua (000504) closed at 9.79, down 3.83% with a trading volume of 85,800 shares and a turnover of 84.73 million yuan [2] - Chengda Pharmaceutical (301201) closed at 30.34, down 3.38% with a trading volume of 104,000 shares and a turnover of 320 million yuan [2] Capital Flow Analysis - The medical services sector experienced a net outflow of 153 million yuan from institutional investors, while retail investors saw a net inflow of 246 million yuan [2][3] - Berry Genomics had a net inflow of 468 million yuan from institutional investors, but a net outflow of 214 million yuan from speculative funds [3] - Haochen Medical saw a net inflow of 116 million yuan from institutional investors, with a net outflow of 82.73 million yuan from speculative funds [3]