Core Insights - Johnson & Johnson Medical Technology launched the ETHICON 4000, the first 3D stapler for laparoscopic surgery in Asia, aimed at enhancing patient outcomes by improving tissue integrity during surgical procedures [1] - The CEREGLIDE 71 distal access catheter made its Asian debut, designed for neurovascular systems, which can reach critical areas in the brain, thus providing timely intervention for stroke patients [2] - The strong and flexible blood flow-directed mesh stent, developed in collaboration with a domestic medical innovation company, was also introduced, showcasing advancements in neurointerventional devices [2] Group 1 - The ETHICON 4000 laparoscopic stapler represents a significant technological advancement, transitioning from 2D to 3D stapling, which enhances the integrity of tissue connections and reduces the risk of complications such as blood leakage [1] - The innovative pre-set chip technology in the ETHICON 4000 allows for dynamic adjustment during the stapling process, potentially decreasing postoperative complications and improving patient recovery [1] Group 2 - The CEREGLIDE 71 distal access catheter is capable of reaching the M1-M2 segments of the brain, facilitating rapid access for stroke treatment, which is critical for patient outcomes [2] - The introduction of a complete thrombectomy product line, including the EMBOTRAP III and EMBOVAC devices, highlights Johnson & Johnson's commitment to advancing neurointerventional solutions [2] - The collaboration with a domestic company to develop the blood flow-directed stent emphasizes the trend of partnerships in the medical technology sector to enhance product offerings and address specific clinical needs [2]

Core Viewpoint - The Shanghai Stock Exchange has accepted the IPO application of Shenzhen Core Medical Technology Co., Ltd., marking it as the first innovative medical device company to be accepted under the newly restarted fifth set of listing standards [1][4]. Group 1: Company Overview - Core Medical is focused on providing artificial heart products and has developed 5 implantable and 6 interventional artificial heart products, with one implantable product already commercialized and two interventional products in the registration approval stage [3]. - The company's first commercialized product, the Corheart6, is the smallest and lightest magnetic levitation implantable artificial heart globally, with the highest cumulative implantation volume and market share in China [3]. Group 2: Financial Status - As of June 30, 2025, Core Medical reported a cumulative undistributed profit of -367 million yuan, indicating it is still in a non-profitable state [4]. - The company aims to raise 1.217 billion yuan through its IPO to support product development, establish an industrialization base for artificial hearts, and enhance its marketing network and digital infrastructure [4]. Group 3: Investment and Market Position - Core Medical has undergone multiple rounds of financing, attracting investments from notable shareholders including Hillhouse Capital, Zhengxin Valley Investment Management, and others [6]. - The acceptance of Core Medical's IPO application under the fifth set of standards exemplifies the Shanghai Stock Exchange's efforts to broaden financing channels for innovative enterprises [5].

本报讯 （记者毛艺融）11月6日，深圳核心医疗科技股份有限公司（以下简称"核心医疗"）科创板IPO 申请获上交所受理，成为重启科创板第五套上市标准后，首家成功获受理的创新医疗（002173）器械公 司。 招股说明书显示，核心医疗获多家资深专业机构投资者投资。根据上交所发布的《发行上市审核规则适 用指引第8号——资深专业机构投资者》，核心医疗认定和披露珠海高瓴私募基金管理有限公司、上海 正心谷投资管理有限公司为其资深专业机构投资者。这也是继珠海泰诺麦博制药股份有限公司后第二家 认定资深专业机构投资者的科创板申报企业。 业内人士认为，此次核心医疗IPO申请获受理，是创新医疗器械领域"科创-资本"双循环的实践落地，也 彰显了科创板为研发投入大、盈利周期长的优质科技企业提供关键资本市场支持的明确导向。 ...

Core Points - Shenzhen Core Medical Technology Co., Ltd. has become the first innovative medical device company to submit an IPO application under the reactivated fifth set of listing standards for the Sci-Tech Innovation Board [1][5] - The company focuses on providing comprehensive, innovative, and high-quality artificial heart products, addressing significant clinical needs in acute and chronic heart failure [3][4] - Core Medical has developed 5 implantable and 6 interventional artificial heart products, with one implantable product already commercialized and two interventional products in the registration approval stage [3][4] Financial Performance - Core Medical has not yet achieved profitability, with projected revenues of approximately 0, 16.55 million, 93.69 million, and 70.48 million CNY for the years 2022 to 2025, and net losses of approximately -178 million, -170 million, -132 million, and -72.75 million CNY for the same periods [4] - As of June 30, the company reported cumulative undistributed profits of -367 million CNY, indicating ongoing financial challenges [4] Market Position and Challenges - The artificial heart industry in China is still in its early development stages, with commercialization affected by factors such as clinical penetration, discipline development, surgical promotion, and patient payment capabilities [4] - Core Medical aims to become the first company to obtain approval for interventional artificial heart products in China, facing challenges in product promotion, market education, and brand building [4][5] IPO Details - The company plans to raise up to 1.217 billion CNY through its IPO, with funds allocated for research and development of circulatory support products, establishment of an artificial heart industrialization base, marketing network and digital construction, and working capital [5] - Core Medical meets the listing standards set forth in the Sci-Tech Innovation Board's regulations, which emphasize technological advancement and research capabilities over short-term financial metrics [5]

钛媒体App 11月6日消息，上交所受理了深圳核心医疗科技股份有限公司（下称"核心医疗"）的科创板 IPO申请，成为重启科创板第五套上市标准后，首家获得受理的创新医疗器械企业。招股说明书显示， 核心医疗获多家资深专业机构投资者投资。这是继珠海泰诺麦博制药股份有限公司后，第二家认定资深 专业机构投资者的科创板申报企业。（科股宝播报） ...

Group 1 - The Shanghai Stock Exchange has accepted the IPO application of Shenzhen Core Medical Technology Co., Ltd., marking it as the first innovative medical device company to be successfully accepted under the new fifth listing standard of the Sci-Tech Innovation Board [1] - Core Medical has undergone multiple rounds of financing, attracting investments from notable shareholders including Hillhouse Capital, Zhengxin Valley Investment, Lianxin Capital, Junlian Capital, Cornerstone Capital, and P7 China [1]

Core Insights - Shenzhen Core Medical Technology Co., Ltd. has received acceptance for its IPO application on the Sci-Tech Innovation Board, marking it as the first innovative medical device company to be accepted under the fifth set of listing standards since their reactivation [1][2] - The company focuses on providing comprehensive, innovative, and high-quality artificial heart products, addressing significant clinical needs in acute and chronic heart failure [1] - Core Medical has achieved key milestones and is expected to have a market value of no less than 4 billion yuan, with its main products requiring approval from relevant national authorities [1] Company Overview - Core Medical is dedicated to the iterative upgrade of artificial heart products through original innovation and key core technology breakthroughs [1] - The company meets the listing criteria outlined in the "Listing Rules," specifically requiring at least one core product to have obtained approval for Phase II clinical trials [1] Industry Context - The acceptance of Core Medical's IPO application highlights the growing market space and potential for innovative medical device companies within the healthcare sector [1][2]

Core Points - Shenzhen Core Medical Technology Co., Ltd. has had its IPO application accepted by the Shanghai Stock Exchange on November 6, marking it as the first innovative medical device company to be accepted under the new fifth set of listing standards for the Sci-Tech Innovation Board [1] - The prospectus indicates that Core Medical has received investments from multiple experienced professional institutional investors [1]

Core Points - Shenzhen Core Medical Technology Co., Ltd. has had its IPO application accepted by the Shanghai Stock Exchange on November 6, marking it as the first innovative medical device company to be accepted under the fifth set of listing standards for the Sci-Tech Innovation Board [1] - The prospectus indicates that Core Medical has received investments from multiple qualified institutional investors, making it the second company after Zhuhai Tenomab Pharmaceutical Co., Ltd. to be recognized as having qualified institutional investors in its Sci-Tech Innovation Board application [1]

Market Overview - The medical services sector increased by 0.55% on November 6, with Haoyuan Pharmaceutical leading the gains [1] - The Shanghai Composite Index closed at 4007.76, up 0.97%, while the Shenzhen Component Index closed at 13452.42, up 1.73% [1] Top Gainers in Medical Services - Haoyuan Pharmaceutical (688131) closed at 77.71, up 4.13% with a trading volume of 44,300 shares and a transaction value of 338 million [1] - Bidai Pharmaceutical (688073) closed at 72.50, up 2.39% with a trading volume of 6,822 shares [1] - Innovative Medical (002173) closed at 24.25, up 2.32% with a trading volume of 448,800 shares and a transaction value of 1.077 billion [1] Top Losers in Medical Services - Baicheng Pharmaceutical (301096) closed at 54.08, down 3.41% with a trading volume of 128,600 shares and a transaction value of 706 million [2] - Berry Genomics (000710) closed at 13.79, down 2.41% with a trading volume of 277,400 shares [2] - Nossger (301333) closed at 64.59, down 2.05% with a trading volume of 33,800 shares [2] Capital Flow Analysis - The medical services sector experienced a net outflow of 472 million from institutional investors, while retail investors saw a net inflow of 280 million [2][3] - Notable net inflows from retail investors were observed in Innovative Medical and other companies, despite overall sector outflows [3] Individual Stock Capital Flow - Innovative Medical had a net outflow of 37.53 million from institutional investors, while retail investors contributed a net inflow of 47.58 million [3] - Haoyuan Pharmaceutical saw a net inflow of 12.35 million from institutional investors, with a slight net outflow from retail investors [3] - Bidai Pharmaceutical had a significant net inflow of 8.77 million from retail investors, despite a net outflow from institutional investors [3]