Group 1 - Overseas institutions conducted research on 214 listed companies in the past 10 days, with Bluestar Technology being the most focused, receiving attention from 38 overseas institutions [1][8] - A total of 566 companies were researched by institutions, with securities companies leading at 537, followed by fund companies at 468 [1][8] - The average stock price of companies researched by overseas institutions increased by 1.13% over the past 10 days, with notable gainers including Kailaiying, which rose by 28.17% [1][8] Group 2 - Among the companies that received attention from overseas institutions, 175 reported annual performance, with Petty Holdings and Hand Information showing significant net profit growth [1][8] - 19 companies issued annual performance forecasts, with 9 expecting profit increases, 3 expecting profits, 4 expecting profit declines, and 2 expecting losses [1][8] - The highest projected net profit growth was for Sitwei, with an expected year-on-year increase of 2671.00% [1][8] Group 3 - The top companies receiving overseas institutional research included Kailaiying, Zhongchong Co., and Nanshan Zhishang, with respective stock price increases of 28.17%, 26.89%, and 26.07% [1][2] - Companies with the largest stock price declines included Aibo Medical, which fell by 23.50%, and others like Yuyue Medical and Xinyuan Technology, which also experienced significant drops [7][8] - The report highlights a diverse range of industries involved, including pharmaceuticals, agriculture, textiles, and electronics, indicating broad interest from overseas institutions [1][8]

Core Viewpoint - Shenzhen Mindray Bio-Medical Electronics Co., Ltd. (Mindray Medical) reported a revenue of 36.726 billion yuan for 2024, marking a year-on-year growth of 5.14%, and a net profit of 11.668 billion yuan, with a growth of 0.74% [2][3] Financial Performance - The company achieved a net cash flow from operating activities of 12.432 billion yuan, reflecting a year-on-year increase of 12.38% [2] - Mindray Medical's revenue and net profit have seen continuous growth for seven consecutive years since its listing, with 2024 revenue being 2.2 times that of 2019 and net profit being 2.5 times that of 2019 [2] Business Segments - The revenue from the Life Information and Support segment reached 13.557 billion yuan, with the minimally invasive surgery business growing over 30% year-on-year [3] - The In-Vitro Diagnostics segment generated 13.765 billion yuan, showing a year-on-year growth of 10.82%, becoming the largest business segment for the first time [3] - The Medical Imaging segment reported revenue of 7.498 billion yuan, with a year-on-year increase of 6.60% [3] R&D and Innovation - Mindray Medical invested 4.008 billion yuan in R&D for 2024, accounting for 10.91% of total revenue, emphasizing its commitment to innovation [3] - The company launched the world's first clinical large model for critical care, named "Qiyuan," enhancing diagnostic precision and quality [4] Market Position and Strategy - Mindray Medical aims to break into the top 20 global medical device rankings, leveraging its competitive advantages in R&D, production, marketing, and service [2] - The company has established numerous successful cases in high-end customer groups both domestically and internationally [5] Shareholder Returns - Mindray Medical plans to distribute a cash dividend of 5.60 yuan per 10 shares, totaling 679 million yuan for 2024, with a cumulative cash dividend of 7.602 billion yuan, representing a payout ratio of 65.15% [6] - The company has consistently paid dividends for seven years without any refinancing, with total dividends reaching 34.111 billion yuan, nearly six times its IPO fundraising amount [6]

Core Viewpoint - The news highlights the performance and potential of state-owned enterprises (SOEs) in China, particularly in the context of ongoing reforms and the integration of artificial intelligence in operations, which may enhance their competitiveness and market performance [2][4]. Group 1: ETF Performance - As of April 29, 2025, the National Enterprise Win-Win ETF (159719) decreased by 0.47%, with a latest price of 1.48 yuan. Over the past week, it has seen a cumulative increase of 0.54% [1]. - The National Enterprise Win-Win ETF had a turnover of 1.2% during the trading session, with a transaction volume of 2.3576 million yuan. The average daily transaction volume over the past year was 17.9394 million yuan [1]. - The Greater Bay Area ETF (512970) increased by 0.43%, with a latest price of 1.16 yuan. Over the past year, it has accumulated a rise of 13.72% [4]. Group 2: Index and Component Stocks - The National Enterprise Win-Win ETF closely tracks the FTSE China National Enterprise Open Win-Win Index, which consists of 100 constituent stocks, including 80 A-share companies and 20 Chinese companies listed in Hong Kong. The top ten constituent stocks are predominantly "China National" stocks [4][6]. - The top ten stocks in the index include China Petroleum, China Petrochemical, China Construction, and China Mobile, with respective weightings of 15.58%, 12.33%, and 8.89% [6]. - The Greater Bay Area Development Theme Index (931000) saw a slight increase of 0.06%, with notable performers including Keda Manufacturing and Weigao Medical, which rose by 6.95% and 4.54%, respectively [4]. Group 3: Policy and Market Outlook - The State-owned Assets Supervision and Administration Commission (SASAC) is actively promoting the "AI+" initiative, focusing on integrating artificial intelligence into enterprise operations to enhance efficiency [1]. - According to Galaxy Securities, SOEs are expected to play a crucial role in China's modernization process, with ongoing reforms aimed at improving core competitiveness and operational efficiency [2]. - The market-oriented operational mechanisms of SOEs are being refined, with plans to implement performance adjustments and exit strategies for underperforming entities by 2025, which may lead to improved profitability [2].

Financial Performance - In 2024, the company achieved total revenue of 36.726 billion CNY, a year-on-year increase of 5.14% [2] - The net profit attributable to shareholders was 11.668 billion CNY, up 0.74% year-on-year; excluding financial expenses, the net profit growth was 4.36% [2] - Operating cash flow reached 12.432 billion CNY, reflecting a year-on-year increase of 12.38% [2] - For Q1 2025, total revenue was 8.237 billion CNY, a decline of 12.12% compared to the same period last year, with net profit down 16.81% [9] Dividend Distribution - The company plans to distribute 679 million CNY (including tax) as dividends for 2024, with a cumulative cash dividend of 7.602 billion CNY, representing a payout ratio of 65.15% [3] - A proposal for a mid-year dividend of 1.71 billion CNY (including tax) for 2025 is also in place, pending shareholder approval [3] Market Performance International Market - The international market grew by 21.28% in 2024, with the Asia-Pacific region seeing nearly 40% growth driven by countries like Australia, Thailand, and India [4] - International revenue accounted for approximately 45% of total revenue, with high-potential segments like minimally invasive surgery and cardiovascular care nearing 10% of international income [4] Domestic Market - The domestic market experienced a decline of 5.10% due to sluggish hospital equipment procurement and the impact of DRG 2.0 [4] - A recovery is anticipated in Q3 2025 as local fiscal pressures ease and medical equipment projects are initiated [4] Product Line Performance In Vitro Diagnostics (IVD) - The IVD segment grew by 10.82% in 2024, with international IVD growth exceeding 30% [5] - IVD revenue now constitutes 37.48% of total company revenue, surpassing the life information and support segment [5] Medical Imaging - The medical imaging segment grew by 6.60%, with international growth over 15% [7] - The launch of the high-end Resona A20 ultrasound is expected to enhance market presence [7] Life Information and Support - This segment saw a decline of 11.11%, although international growth was in double digits [8] - The company maintains a leading market share in domestic monitoring and respiratory devices despite challenges [8] Research and Development - R&D investment for 2024 was 4.008 billion CNY, accounting for 10.91% of revenue, while Q1 2025 saw 847 million CNY in R&D, representing 10.28% of revenue [11] - New product launches include advanced systems in life information and support, IVD, and medical imaging [12][13] Sustainability Efforts - The company received an AA rating from MSCI ESG and was included in the S&P Global Sustainable Development Yearbook [14] - Carbon emissions intensity decreased by 11.6% compared to 2021, with ongoing projects contributing to sustainability goals [15] Future Outlook - The company anticipates a significant recovery in domestic revenue starting Q3 2025, driven by the resumption of medical equipment projects [10] - Long-term growth strategies focus on digitalization, internationalization, and enhancing the supply chain to adapt to changing market conditions [24][25]

Investment Rating - The report maintains a positive investment rating for the pharmaceutical industry, focusing on innovation and growth opportunities in various segments [4]. Core Insights - The pharmaceutical sector is experiencing a comprehensive recovery, with a focus on innovative drug development, particularly in oncology, autoimmune diseases, GLP-1, stem cell therapy, and gene therapy [1][2]. - The report highlights the importance of domestic innovation in pharmaceuticals, with significant attention on the upcoming AACR and ASCO conferences, where numerous Chinese companies are expected to present their research [2][13]. - The report emphasizes the potential for growth in the CXO sector due to recovering domestic demand and stable overseas demand, suggesting a valuation recovery for leading companies [8]. - The report identifies key companies to watch, including 恒瑞医药, 百济神州, and others across various segments such as innovative drugs, medical devices, and IVD [3]. Summary by Sections Innovative Drugs - The report notes the approval of 康方依沃西单抗 for first-line treatment of PD-L1 positive NSCLC, showing a 22.3% reduction in mortality risk [2]. - It highlights the upcoming AACR conference with over 120 Chinese pharmaceutical companies presenting nearly 300 new drug research results [13]. CXO Sector - The CXO sector is expected to benefit from supportive policies and a reduction in geopolitical risks, leading to a potential valuation uplift [8]. Traditional Chinese Medicine - The report suggests monitoring companies related to pediatric medications, such as 济川药业 and 葵花药业, due to their relevance to fertility subsidies [2]. Blood Products - The report emphasizes the growth potential in the immunoglobulin market over the next 3-5 years, driven by increased demand and pricing improvements [2][25]. Vaccines - The vaccine sector is under pressure, but there are opportunities in HPV vaccines and other high-value products [27]. Upstream Supply Chain - The report recommends focusing on companies with strong brand recognition and overseas growth potential in the chemical and biological reagent sectors [30]. IVD Sector - The report indicates that the IVD industry is poised for growth due to the implementation of centralized procurement policies and increasing domestic demand [33]. Medical Devices - The report highlights the potential for growth in the CGM market, particularly with the FDA approval of related products [38]. Medical Services - The report suggests focusing on eye and dental medical service companies, anticipating a boost from consumer stimulus policies [44]. Offline Pharmacies - The report notes that the pharmacy sector is stabilizing, with a recommendation to focus on companies with strong supply chain capabilities [46]. Raw Materials - The report discusses the importance of quality and cost management in the raw materials sector, suggesting a focus on companies with strong product capabilities [50]. Innovative Devices - The report emphasizes the potential for AI applications in medical devices, particularly in surgical navigation and pathology screening [53]. Instrumentation - The report anticipates a recovery in the scientific instrumentation sector, driven by increased domestic demand and new product launches [57].

Investment Rating - The report maintains a positive investment rating for the pharmaceutical industry, highlighting a recovery and focus on innovation [4]. Core Views - The pharmaceutical sector is experiencing a sustained recovery in fundamentals, supported by favorable policies, with a focus on innovative drug growth, particularly in areas such as oncology, autoimmune diseases, GLP-1, stem cell therapy, and gene therapy [1][2]. - The report emphasizes the importance of domestic pharmaceutical substitution and the growth of medical consumption, especially in aesthetic medicine [1]. Summary by Sections Innovative Drugs - The AACR conference is ongoing, with significant participation from over 120 Chinese pharmaceutical companies presenting nearly 300 new drug research results [11]. - Key approvals include the domestic approval of 康方依沃西单抗 for PD-L1 positive NSCLC and the FDA approval of 派安普利单抗 for nasopharyngeal carcinoma [2][72]. CXO Sector - The CXO sector is expected to see valuation recovery due to supportive policies for innovative drug development and a reduction in geopolitical risks [6]. Traditional Chinese Medicine - The SW secondary index for traditional Chinese medicine has underperformed compared to the broader market, indicating challenges in this segment [19]. Blood Products - The report highlights the increasing demand for immunoglobulin products and the potential for price improvements in the blood products sector, particularly for companies like 天坛生物 and 派林生物 [23]. Vaccines - The vaccine sector is facing challenges due to low birth rates, but there is potential for growth in HPV vaccines and other areas [25]. Upstream Supply Chain - The report suggests focusing on companies with strong brand and operational capabilities in the chemical and biological reagent sectors [28]. IVD (In Vitro Diagnostics) - The IVD industry is expected to benefit from the implementation of centralized procurement policies, which may accelerate domestic substitution [31]. Medical Devices - The report recommends attention to the CGM market, particularly products from 三诺生物, as they align with the growth of GLP-1 drugs [36]. Medical Services - The report suggests focusing on eye and dental medical service companies, anticipating a boost from consumer stimulus policies [43]. Offline Pharmacies - The offline pharmacy sector is stabilizing, with a recommendation to focus on companies with strong supply chain capabilities [45]. Raw Materials - The report emphasizes the importance of quality and cost management in the raw materials sector, suggesting a focus on companies like 华海药业 and 海正药业 [49]. Innovative Instruments - The report highlights the potential for AI applications in the medical device sector, particularly in surgical navigation and pathology screening [52]. Instrument Equipment - The scientific instrument sector is expected to recover as demand improves, with a focus on companies enhancing their market presence through new product launches [57]. Low-value Consumables - The report notes a potential recovery in the low-value consumables sector, particularly for companies like 采纳股份 and 美好医疗 [60].

上述募集资金到位情况已由普华永道中天会计师事务所（特殊普通合伙）审 验，并已于 2018 年 10 月 10 日出具"普华永道中天验字(2018)第 0626 号"《验 资报告》。公司已对募集资金采取了专户存储，相关募集资金已全部存放于募集 资金专户，并且公司及相关子公司与存放募集资金的商业银行、保荐机构签订了 《募集资金三方监管协议》、《募集资金四方监管协议》。 二、募集资金投资项目的基本情况 根据《深圳迈瑞生物医疗电子股份有限公司首次公开发行股票并在创业板上 市招股说明书》及公司召开的第七届董事会第三次会议、第七届董事会第五次会 议、第七届董事会第十次会议、2019 年年度股东大会和 2020 年年度股东大会， 1 核查意见 华泰联合证券有限责任公司 关于深圳迈瑞生物医疗电子股份有限公司 部分募集资金投资项目结项 并将节余募集资金永久补充流动资金的公告 华泰联合证券有限责任公司（以下简称"华泰联合证券"、"保荐机构"）作 为深圳迈瑞生物医疗电子股份有限公司（以下简称"迈瑞医疗"、"公司"）首次 公开发行股票并在创业板上市持续督导阶段的保荐机构，根据《证券发行上市保 荐业务管理办法》、《上市公司监管指引第 ...

深圳迈瑞生物医疗电子股份有限公司 2024年度内部控制审计报告 安永华明（2025）专字第70024693_H01号 深圳迈瑞生物医疗电子股份有限公司 深圳迈瑞生物医疗电子股份有限公司全体股东： 按照《企业内部控制审计指引》及中国注册会计师执业准则的相关要求，我们审计 了深圳迈瑞生物医疗电子股份有限公司 2024 年 12 月 31 日的财务报告内部控制的有效 性。 一、企业对内部控制的责任 按照《企业内部控制基本规范》、《企业内部控制应用指引》、《企业内部控制评价指 引》的规定，建立健全和有效实施内部控制，并评价其有效性是深圳迈瑞生物医疗电子 股份有限公司董事会的责任。 二、注册会计师的责任 我们的责任是在实施审计工作的基础上，对财务报告内部控制的有效性发表审计意 见，并对注意到的非财务报告内部控制的重大缺陷进行披露。 按照中国证监会发布《上市公司实施企业内部控制规范体系监管问题解答》（2011 年第 1 期，总第 1 期）的相关豁免规定，深圳迈瑞生物医疗电子股份有限公司未将于 2024 年度并购的子公司深圳惠泰医疗器械股份有限公司及其下属子公司（"惠泰医疗集 团"）的内部控制包括在深圳迈瑞生物医疗电子股份 ...

Group 1: Poly Developments - Poly Developments reported a net profit of 5 billion yuan for 2024, a decrease of 58.6% year-on-year [1] - The company achieved total revenue of 311.67 billion yuan in 2024, down 10% from the previous year [2] - The gross profit margin for settlements was 14%, a decline of 2 percentage points compared to the same period last year [1][2] - The company signed a total area of 17.9661 million square meters, a decrease of 24.7% year-on-year, while sales contracts amounted to 323.029 billion yuan, down 23.5% [2] - The company maintained a cash balance of 134.2 billion yuan at the end of the year, with a net cash flow from operating activities of 6.257 billion yuan [3] Group 2: Mindray Medical - Mindray Medical reported a revenue of 36.726 billion yuan for 2024, an increase of 5.14% year-on-year [5][6] - The net profit attributable to shareholders was 11.668 billion yuan, a slight increase of 0.74% compared to the previous year [5][6] - The company's cash flow from operating activities was not disclosed in the provided data [6] Group 3: Unisplendour - Unisplendour announced plans to issue H-shares and apply for listing on the Hong Kong Stock Exchange [9] - The company achieved a revenue of 79.024 billion yuan in 2024, a growth of 2.22% year-on-year [10] - The net profit attributable to shareholders was 1.572 billion yuan, a decrease of 25.23% compared to the previous year [10] Group 4: SF Holding - SF Holding reported a revenue of 69.849 billion yuan for the first quarter, an increase of 6.9% year-on-year [17][18] - The net profit attributable to shareholders was 2.234 billion yuan, reflecting a growth of 16.9% compared to the same period last year [17][18] - The company plans to repurchase shares worth between 500 million and 1 billion yuan [17] Group 5: Qingdao Beer - Qingdao Beer reported a revenue of 10.445 billion yuan for the first quarter, a growth of 2.91% year-on-year [20][21] - The net profit attributable to shareholders was 1.710 billion yuan, an increase of 7.08% compared to the previous year [20][21] Group 6: China State Construction - China State Construction reported a revenue of 555.3 billion yuan for the first quarter, a growth of 1.1% year-on-year [23] - The net profit attributable to shareholders was 15.01 billion yuan, reflecting a growth of 0.6% compared to the same period last year [23] Group 7: WuXi AppTec - WuXi AppTec reported a revenue of 9.655 billion yuan for the first quarter, a growth of 20.96% year-on-year [24] - The net profit attributable to shareholders was 3.672 billion yuan, a significant increase of 89.06% compared to the previous year [24] Group 8: China Nuclear Power - China Nuclear Power reported a revenue of 20.273 billion yuan for the first quarter, a growth of 12.7% year-on-year [25] - The net profit attributable to shareholders was 3.137 billion yuan, reflecting a growth of 2.55% compared to the same period last year [25] Group 9: Haitian Flavoring - Haitian Flavoring reported a revenue of 8.315 billion yuan for the first quarter, a growth of 8.08% year-on-year [26] - The net profit attributable to shareholders was 2.202 billion yuan, an increase of 14.77% compared to the previous year [26] Group 10: Yunnan Baiyao - Yunnan Baiyao reported a revenue of 10.841 billion yuan for the first quarter, a growth of 0.62% year-on-year [27] - The net profit attributable to shareholders was 1.935 billion yuan, reflecting a growth of 13.67% compared to the same period last year [27]

子公司管理制度 第一章 总则 若公司合并报表范围内的子公司属于上市公司的，在不违背该等上市子公 司股票上市地证券监管规则的前提下，其仍应当适用本制度的相关规定和 要求。 第三条 各子公司应遵循本制度, 结合公司的相关内部控制规定, 根据自身经营 特点, 可制定具体的实施细则, 以保证本制度的贯彻和执行。公司各职能 部门应按相关内控制度, 及时对子公司做好服务、指导、监督等工作。 公司亦可结合各子公司的组织架构、内部控制特点，在符合法律法规的前 提下，对组织架构或职能较为简单的子公司采取垂直管理、直接管理等管 理方式，并及时对子公司做好服务、指导、监督等工作。 第四条 公司的子公司同时控股其他公司的, 应参照本制度的要求逐层建立对其 1 第一条 为加强深圳迈瑞生物医疗电子股份有限公司(以下简称"公司")内部控 制, 促进公司规范运作和健康发展, 保护投资者合法权益, 加强对控股 子公司(或称"子公司")的管理控制, 规范控股子公司行为, 保证控股 子公司规范运作和依法经营, 根据《中华人民共和国公司法》《中华人民 共和国证券法》等法律法规和规范性文件, 以及《深圳迈瑞生物医疗电子 股份有限公司章程》(以下简称" ...