Nam, could you just tell us about the shift that's taking place right now in the global market for for weight loss drugs. >> So, I mean, we're we're going really from a few years where Novon Nordisk couldn't make enough semiglutide to supply the market um in the US, let alone in the rest of the world. um to a time when um in a growing number of countries there will be a lot of generic competitors on the market and people will suddenly have access that they never had before to super powerful obesity medicine ...

Market Overview - Eli Lilly and Novo Nordisk are leading the weight loss drug market, which is projected to reach nearly $100 billion by 2030 due to soaring demand [1] - The market has experienced product shortages at times, indicating strong consumer interest and demand [1] Product Launches - Novo Nordisk was the first to market with semaglutide, branded as Ozempic for type 2 diabetes and Wegovy for weight loss, with approvals in 2017 and 2021 respectively [2][4] - Eli Lilly entered the market later with tirzepatide, marketed as Mounjaro for type 2 diabetes and Zepbound for weight loss, receiving approvals in 2022 and 2023 [5] Competitive Dynamics - Despite the challenges of entering a market with established products, Eli Lilly has successfully gained market share due to strong demand and strategic manufacturing investments [5] - A head-to-head study indicated that Zepbound may be more effective than Wegovy, with Zepbound achieving over 20% average weight loss compared to over 13% for Wegovy after 72 weeks [6] Market Share Trends - As of May 2024, Eli Lilly began to gain market share in the U.S. incretin analog market, while Novo Nordisk started to lose share [7] - Currently, Eli Lilly holds over 60% of the market share, compared to approximately 39% for Novo Nordisk, indicating a significant shift in competitive positioning [7]

Novo Nordisk A/S (NYSE:NVO) is trading higher on Friday after falling for two consecutive days on lower-than-expected fiscal 2026 guidance and compounding concerns. • Novo Nordisk stock is showing exceptional strength. What’s behind NVO gains?On Tuesday, the company said it expects adjusted sales growth for 2026, which excludes revenue from the reversal of 340B provisions, to be -5% to -13% at constant exchange rates (CER).Hims and Hers said that eligible customers can access treatment plans that include Co ...

Group 1 - The share price of Novo Nordisk A/S (NVO) experienced significant appreciation at the start of 2026 but faced a drastic decline following an announcement [1] - The company is noted for its strong fundamentals and good cash flows, making it an attractive option for long-term value investing despite market fluctuations [1] - The analyst expresses a focus on undervalued companies and sectors, particularly in Oil & Gas and consumer goods, which may offer substantial returns [1] Group 2 - The analyst holds a beneficial long position in NVO shares, indicating confidence in the company's future performance [2] - The article reflects the analyst's personal opinions and is not influenced by compensation from any company mentioned [2] - Seeking Alpha emphasizes that past performance does not guarantee future results and that the views expressed may not represent the platform as a whole [3]

Core Viewpoint - Novo Nordisk's stock has experienced a significant decline of over 20% this week and is down 68% from its all-time highs in early 2024, primarily due to weak guidance for 2026 and increasing competition in the weight-loss drug market [1][2][3]. Financial Performance - Novo Nordisk reported a revenue growth of 10% year-over-year in constant currency for 2025, despite facing pressure from competitors like Eli Lilly [2]. - The company's guidance for 2026 indicates a potential decline in sales and earnings by 5%-13% compared to 2025, raising concerns among investors [3]. Competitive Landscape - The weight-loss drug market is becoming increasingly competitive, with new entrants like the TrumpRx website offering discounted versions of Novo Nordisk's products, including Wegovy [3]. - Generic versions of weight-loss drugs are already available in some countries, which management anticipates will negatively impact sales [4]. - Telehealth marketplace Hims & Hers has launched a competing product at a significantly lower price, adding further uncertainty to Novo Nordisk's market position [4]. Historical Context - The current price drawdown represents the worst in Novo Nordisk's history since 1990, although the stock has delivered a cumulative total return of over 30,000% for shareholders since then [5]. Business Outlook - Novo Nordisk has a long history of steady innovations, having first invented insulin over 100 years ago, and continues to focus on weight-loss drugs as a major market opportunity [6]. - The stock is currently trading at a price-to-earnings ratio (P/E) of 13, suggesting that investors are heavily discounting the company's ability to maintain market share in weight-loss drugs and any future innovations [7].

Core Viewpoint - The two leading companies in the weight-loss drug market, Novo Nordisk and Eli Lilly, have provided contrasting outlooks on the future of the industry, highlighting uncertainties regarding demand, supply, and pricing dynamics [1][2]. Market Dynamics - The weight-loss drug market, particularly for GLP-1 medicines, has seen a surge in demand that consistently outpaces supply, leading to reported shortages and delays for patients [3][4]. - Novo Nordisk's semaglutide and Eli Lilly's tirzepatide are key products in this market, both demonstrating significant weight loss and improved metabolic outcomes in clinical trials [4]. Supply and Coverage Challenges - Capacity issues are critical, as building manufacturing capabilities requires time and investment, with potential delays impacting pharmacies and clinics [6]. - Insurance coverage remains a significant concern, with varying levels of access based on employer and health plan decisions, affecting patient affordability and availability [7]. Investor Insights - Mixed guidance from the two companies may lead to short-term stock volatility, with investors closely monitoring production updates, regulatory approvals, and pricing strategies [8]. - The market's future will depend on the ability of companies to align capacity expansion with payer negotiations and demand management [14]. Future Trends - Several trends could influence the market, including potential cardiovascular outcome data that may expand coverage, the introduction of oral GLP-1 formulations, and regulatory validation of manufacturing investments [12]. - Analysts suggest multiple scenarios for the market's trajectory, ranging from steady growth with expanded supply and coverage to potential slowdowns due to bottlenecks and tighter budgets [13]. Conclusion - The current landscape indicates strong market demand and differing company outlooks, necessitating close monitoring of production milestones, payer decisions, and regulatory developments to gauge the market's direction [15].

这一价格远低于诺和诺德在其直连消费者的官网诺和关怀上的定价 —— 该平台上，维格卫起始剂量的 售价为 149 美元。 来源：环球市场播报 作者：埃尔莎・奥伦 这张图片为示意图，智能手机屏幕上显示着 Hims & Hers 健康公司的品牌标识。 受诺和诺德发出法律威胁影响，远程医疗企业 Hims & Hers 的股价在本周五早盘交易中走低。 这家线上远程医疗公司于周四宣布，计划推出诺和诺德减肥药丸的平价仿制品，此举直接引发诺和诺德 采取法律行动。 消息传出后，Hims 的股价在周四的交易中一度飙升 15%，但在诺和诺德指认该行为 "涉嫌违法" 后，股 价迅速回吐涨幅，最终收跌 3.8%，创 12 个月新低；本周五早盘交易中，其股价再度下跌 6.5%。 Hims 方面表示，将推出一款维格卫同款减肥药丸，其有效成分与原研药一致，均为司美格鲁肽。用户 订阅后，首月用药价格低至 49 美元，首月过后，价格将上调至 99 美元。 与此同时，巴克莱银行分析师詹姆斯・戈登认为，这款定价 49 美元的维格卫仿制品，成为诺和诺德面 临的 "新隐患"。 他补充道："尽管这类复合仿制药短期内可能吸引对价格敏感的患者，但该类产品的监管 ...

Core Insights - Hims & Hers Health, Inc. is entering the weight-loss market with a new compounded semaglutide pill, offering a needle-free alternative to existing injectable options from competitors like Novo Nordisk and Eli Lilly [1][7] Pricing Strategy - The compounded oral semaglutide pill is introduced at an introductory price of $49 for the first month, followed by $99 per month for the subsequent four months, making it a more accessible option compared to the higher-priced injectables [2] Market Impact - Following the announcement of Hims & Hers' new product, shares of Novo Nordisk and Eli Lilly experienced significant declines, indicating potential disruption in their market dominance [3][7] Competitive Landscape - Novo Nordisk's Wegovy and Ozempic have seen commercial success, with Wegovy priced at approximately $149 per month for its starting dose, while Eli Lilly's tirzepatide products have also contributed significantly to its growth [4][6][5] Regulatory Concerns - Novo Nordisk plans to pursue legal actions to protect its intellectual property and has raised concerns about the safety and effectiveness of compounded GLP-1 therapies, which are not FDA-approved [7][8][9] Stock Performance - Hims & Hers stock initially rose but fell by 3.77% by the end of the trading day, while Novo Nordisk and Eli Lilly also saw declines of 8% and 7.8%, respectively, amid broader market reactions [11][12]

Core Viewpoint - Hims & Hers Health has launched a compounded semaglutide pill priced at $49, causing a 6.2% drop in its stock and putting pressure on competitors Novo Nordisk and Eli Lilly, with Novo Nordisk planning legal action against the compounded drug practices [1][1]. Company Summary - Hims & Hers Health's stock fell by 6.2% following the introduction of a compounded semaglutide pill [1]. - The new product is priced at $49, which is significantly lower than existing options in the market [1]. Industry Summary - The launch of the compounded semaglutide pill by Hims & Hers Health is expected to create competitive pressure on major pharmaceutical companies like Novo Nordisk and Eli Lilly [1]. - Novo Nordisk has vowed to take legal action against the large-scale compounded drug practices initiated by Hims & Hers Health [1].

Novo Nordisk’s patents on semaglutide, the active ingredient in Ozempic, are starting to expire. On the Big Take podcast, @davidgura talks to @naomikresge and @AmberTongPW about how the company is navigating a dire 2026 sales projection https://t.co/vFQ40vZGYb ...