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Can-Fite Granted Brazilian Patent for Treatment of Sexual Dysfunction
Globenewswire· 2025-12-26 12:00
Core Insights - Can-Fite BioPharma Ltd. has received a patent from the Brazilian Patent Office for the use of A3 Adenosine Receptor Agonists in treating sexual dysfunction, enhancing its intellectual property portfolio in a significant pharmaceutical market [1][3] Group 1: Patent and Market Implications - The granted patent provides protection in Brazil for Can-Fite's proprietary A3AR agonists, which is crucial as Brazil is one of the largest pharmaceutical markets in Latin America with increasing demand for innovative sexual health therapies [1][2] - The patent validates the therapeutic versatility of A3 adenosine receptor agonists and may lead to future commercialization opportunities in Latin America [3] Group 2: Company Overview and Drug Development - Can-Fite is an advanced clinical stage drug development company targeting multi-billion-dollar markets in cancer, liver, and inflammatory diseases [4] - The company's lead drug candidate, Piclidenoson, has reported topline results in a Phase III trial for psoriasis and is advancing in other trials for hepatocellular carcinoma and pancreatic cancer [4] - Can-Fite's drug candidate Namodenoson has received Orphan Drug Designation in the U.S. and Europe and is being evaluated in multiple clinical trials [4]
Oracle shares on pace for worst quarter since 2001 as new CEOs face concerns about AI buildout
CNBC· 2025-12-26 12:00
Core Viewpoint - Oracle's new CEOs, Clay Magouyrk and Mike Sicilia, are facing significant challenges as the company's stock has dropped 30% this quarter, marking its steepest decline since 2001 and the dot-com bust [1][2]. Financial Performance - Oracle reported weaker-than-expected quarterly revenue and free cash flow, prompting the new finance leader to announce a $50 billion capital expenditure plan for fiscal 2026, which is 43% higher than previously planned and double the amount from the previous year [3]. - The company is also planning $248 billion in leases to enhance cloud capacity alongside building new data centers [3]. Debt and Investment Concerns - To support its growth plans, Oracle raised $18 billion in a significant bond sale, one of the largest in the tech industry, raising concerns about its ability to maintain an investment-grade debt rating [4]. - Analysts express skepticism about Oracle's capacity to meet its financial obligations without restructuring its contract with OpenAI, which has committed over $300 billion to Oracle [5]. Market Position and Growth Strategy - Oracle's revenue backlog surged by 359% due to its agreement with OpenAI, which initially boosted its stock by nearly 36% [8]. - The company aims to increase revenue to $225 billion by fiscal 2030, primarily driven by AI infrastructure, although this growth may come at the expense of profitability, with gross margins expected to decline from 77% in fiscal 2021 to about 49% by 2030 [15][16]. Investor Sentiment - Some investors remain cautious about Oracle's long-term plans, particularly its heavy reliance on OpenAI, which is facing its own financial challenges [17]. - Analysts have mixed views, with some issuing buy ratings based on potential revenue growth from OpenAI, while others highlight the need for Oracle to improve its market share in cloud infrastructure, where it lags behind competitors like Amazon and Microsoft [18][19].
American Pacific Announces Share Payments to Three Former Employees
TMX Newsfile· 2025-12-26 12:00
Core Viewpoint - American Pacific Mining Corp. will issue 1,281,722 common shares at a deemed price of $0.175 per share to former employees, fulfilling employment-related liabilities totaling $224,301.35, expected to close on January 5, 2026, pending regulatory approvals [1]. Company Overview - American Pacific Mining Corp. is focused on precious and base metals exploration and development in the Western United States, with its flagship asset being the 100%-owned Madison Copper-Gold Project in Montana [3]. - The company has established a significant equity position in the Palmer Copper-Zinc VMS Project in Alaska through a transaction with Vizsla Copper, securing $15 million in milestone upside exposure [3]. - American Pacific's portfolio includes several high-grade precious metals projects in key mining districts in Nevada, with plans for partnerships, spin-outs, and direct exploration to provide shareholders with discovery and exploration upside [3].
Wall Street Breakfast Podcast: Three Forces That Defined 2025
Seeking Alpha· 2025-12-26 11:54
Group 1: Consumer Sentiment and Economic Indicators - Consumer sentiment for December was revised down to 52.9 from an initial estimate of 53.3, although it improved from 51.0 in November [4] - The Consumer Price Index rose 2.7% year-over-year in November, with regional variations; for example, inflation in Southern California was 4.5% compared to 1.1% in Dallas [4] - Year-ahead inflation expectations declined for the fourth consecutive month to 4.2%, the lowest level in 11 months, but still above the 3.3% recorded in January [5] Group 2: Capital Expenditures in the Tech Industry - Major tech companies, including Alphabet, Amazon, Microsoft, and Meta, are significantly increasing their capital expenditures (CapEx) in AI infrastructure as competition intensifies [9] - Meta expects its 2025 CapEx to be in the range of $70 billion to $72 billion, up from a prior outlook of $66 billion to $72 billion [10] - Alphabet raised its CapEx forecast for 2025 and 2026 to between $91 billion and $93 billion, up from a previous estimate of $85 billion [12] - Amazon reported cash CapEx of $34.2 billion in Q3 and a total of $89.9 billion spent so far this year, emphasizing continued significant investments in AI [13] Group 3: Market Outlook and Predictions - The S&P 500 is predicted to rise another 10-15% in 2026, driven by strong spending in technology and the resilience of major companies against tariffs [14] - The tech sector is expected to maintain expanding profit margins even as it enters lower-margin businesses like AI [14]
Wall Street Breakfast Podcast: Three Forces Defined 2025
Seeking Alpha· 2025-12-26 11:54
baona/iStock via Getty Images Listen below or on the go via Apple Podcasts and Spotify Consumer sentiment revised lower for December as year-ahead inflation expectation revised up a tick. Tech giants brace to spend billions more in CapEx as AI race heats up. 2026 S&P 500 Outlook: I'm The Lone Bull In The China Shop. This is an abridged transcript. 2025….has been a year. But don’t we say the same thing at the end of every year? Well, today we’re looking at the year as a whole and remembering three big ...
5 ways to start the new year with less debt, according to experts
Yahoo Finance· 2025-12-26 11:43
Core Insights - The article emphasizes the importance of resetting financial habits in January to effectively manage and pay down debt, suggesting that even small changes can lead to significant progress by the end of the year [1][2] Group 1: Debt Management Strategies - Reviewing credit reports is crucial for identifying errors that can save money and improve credit scores, which can lead to lower interest rates [4][5] - Tracking spending helps individuals recognize spending patterns and encourages better financial habits, making it easier to allocate funds toward debt repayment [6][7][8] - Automating debt payments ensures consistent progress in paying down debt and reduces the risk of late payments, which can protect credit scores [9][10] Group 2: Psychological and Behavioral Approaches - Overcoming negative self-talk about financial management is essential for maintaining motivation in debt repayment; focusing on small wins can build confidence [10][11] - Implementing a 90-day spending freeze can help individuals redirect funds from non-essential spending to high-interest debt, promoting a reset in financial habits [12][13][14]
Alphabet Under $330: Your Last Chance to Buy?
The Motley Fool· 2025-12-26 11:41
Alphabet stock is down slightly from its November high. Here's why that's an opportunity, not a warning sign.Six years ago, on Dec. 23, 2019, I could have sold my Alphabet (GOOG +0.00%) (GOOGL 0.12%) shares at a market-crushing profit. After almost exactly nine years in my portfolio, my Alphabet Class A stock was up by 348%. The S&P 500 (^GSPC +0.32%) had gained 156% over the same period.But I didn't rebalance this successful position. Now, those Alphabet shares have gained a total of 2,084% (or 2,096% if y ...
What to Expect From Textron's Next Quarterly Earnings Report
Yahoo Finance· 2025-12-26 11:30
Providence, Rhode Island-based Textron Inc. (TXT) designs, manufactures, and supports a wide range of products and technologies across aerospace, defense, specialized industrial, and finance sectors. Valued at a market cap of $16 billion, the company is scheduled to announce its fiscal Q4 earnings for 2025 in the near future. Before this event, analysts expect this aerospace and defense company to report a profit of $1.78 per share, up 32.8% from $1.34 per share in the year-ago quarter. The company has s ...
Is Robinhood a Buy, Sell, or Hold in 2026?
The Motley Fool· 2025-12-26 11:30
Core Viewpoint - Robinhood's stock has surged over 200% in 2025 due to user base expansion and platform enhancements, but concerns exist regarding its ability to maintain this momentum in 2026 [1][2]. Financial Performance - Robinhood's revenue doubled to $1.3 billion in Q3, with non-GAAP earnings increasing by 259% to $0.61 per share [4]. - The average revenue per user rose by 82% to $191, and total users reached 26.8 million, a 10% increase year-over-year [4]. Market Context - The company's growth is significantly tied to the booming stock market, with the S&P 500 gaining 75% over the past three years and Bitcoin rising over 400% [5]. - Robinhood's revenue is heavily reliant on transactions from crypto investments and options trading, which are considered risky segments [6]. Economic Vulnerability - Robinhood has not yet faced a bear market since going public in 2021, raising concerns about its resilience during economic downturns [7]. - Current economic indicators show rising unemployment at 4.6% and a 22-year high in layoffs for October, suggesting potential economic slowdown [10]. Investment Outlook - Investors may consider holding onto Robinhood shares as long as the company continues to improve, but caution is advised due to potential declines if the U.S. economy slows [9]. - A significant market downturn could lead to a rapid sell-off of stocks, particularly among younger investors who have not experienced a bear market [11]. - It may be prudent for Robinhood investors to take profits soon rather than waiting for further gains in 2026, as the company has not demonstrated its ability to grow during prolonged market declines [12].
Gen X is behind on retirement savings more than any other generation. Here’s how to catch up and secure your future
Yahoo Finance· 2025-12-26 11:30
Core Insights - Generation X is facing a retirement crisis, with a report indicating they have a "fragile retirement foundation" and may enter retirement less secure than any previous generation [1][2] - The median retirement savings for Gen X is alarmingly low, with women saving $6,000 and men saving $13,000, and only 14% have access to traditional pensions compared to 56% of baby boomers [1] Group 1: Financial Preparedness - Generation X, born between 1965 and 1980, is currently aged 45 to 60, a critical period for increasing retirement savings [2] - This generation is often referred to as the "sandwich generation," as they are financially supporting both aging parents and their own children, leading to inadequate retirement preparation [2] Group 2: Economic Challenges - Gen X has experienced eight recessions, rising higher education costs, and significant stock market corrections, contributing to their financial struggles [4] - The shift from traditional pensions to defined contribution plans has placed the responsibility of retirement savings on workers, which has negatively impacted Gen X's financial security [5] Group 3: Reliance on Social Security - The report highlights that Social Security is facing "structural shortfalls," and Gen X is expected to rely heavily on it, despite it only being designed to replace about 40% of a retiree's pre-retirement income [5]