Avidity Biosciences – the San Diego rare disease biotech being acquired by Novartis for $12 billion – is spinning off its early-stage cardiology unit into a new company called Atrium Therapeutics. In a move that gives Avidity’s shareholders a parting gift as they surrender the rest of the company to Novartis, Avidity’s board designated February 12, 2026 as the record date (close of business, Eastern Time) for the pro rata distribution of Atrium shares ( PR Newswire ). Each Avidity holder on that date will r ...

Novo Nordisk downgraded by leading banks as CagriSema trial flops against Zepbound Proactive uses images sourced from Shutterstock The failure of its next-generation obesity drug to match Eli Lilly's blockbuster has blown a hole in Novo's post-Ozempic strategy, with analysts slashing price targets and two major banks walking away from bullish positions Novo Nordisk's (NYSE:NVO) last best hope for life after semaglutide has stumbled badly. The Danish drugmaker's CagriSema combination jab failed on Monday to ...

Core Insights - Novo Nordisk's recent trial data for its obesity drug CagriSema has underperformed compared to Eli Lilly's Zepbound, raising concerns about Novo's competitiveness in the weight-loss drug market [1] - Following the trial results, Novo's shares dropped by 16%, while Lilly's shares increased by 5%, indicating a shift in market sentiment towards Lilly's products [1] - Analysts express skepticism about Novo's ability to regain market share, citing repeated disappointments with CagriSema and the strong positioning of Lilly's portfolio [1] Novo Nordisk's Performance - CagriSema achieved a 23% reduction in body weight over 84 weeks, compared to a 25.5% reduction for Lilly's tirzepatide [1] - The trial results align with previous data for CagriSema but are seen as inferior to Lilly's offerings, which could solidify Lilly's dominance in the obesity market [1] - Novo's management attempted to downplay the trial results, but analysts and investors remain unconvinced, questioning the drug's value proposition [1] Market Dynamics - The obesity drug market is increasingly favoring Lilly, which has a stronger product range and is expected to receive U.S. approval for its weight-loss pill in April [1] - Novo's historical lead in the obesity drug market, particularly with the launch of Wegovy in 2021, has diminished as Lilly's valuation has surged to a trillion dollars [1] - Analysts suggest that Novo may struggle to compete effectively against Lilly's Zepbound, which is already well-established in the market [1]

Novo Nordisk AS (NYSE:NVO) , once the darling of the pharmaceutical world, tumbled Monday as investors reacted to what analysts are calling a “worst-case scenario.” NVO stock is tumbling. See the chart and price action here. Shares of Novo Nordisk stock plunged over 16% in morning trading, hitting a new 52-week low following disappointing results from the REDEFINE 4 Phase 3 clinical trial. This latest blow brings the stock’s one month decline to 36%.The Data Gap: CagriSema vs. TirzepatideThe 84-week trial i ...

LOS ANGELES--(BUSINESS WIRE)--The Schall Law Firm, a national shareholder rights litigation firm, announces that it is investigating claims on behalf of investors of Novo Nordisk A/S ("Novo Nordisk†or "the Company†) (NYSE: NVO) for violations of the securities laws. The investigation focuses on whether the Company issued false and/or misleading statements and/or failed to disclose information pertinent to investors. Novo Nordisk is the subject of a report by CNBC published on February 23, 2026, titled: "N ...

Now, Hims and Hers is set to report earnings after the close today. So, to help us preview the results, I'd now like to welcome in our next guest, Raul Shaw, CEO of Doc Shaw Financial. And so, Raul will thank you so much for kicking off this week with us, what are your overall expectations for him and hers given the fact that this name has has taken it on the chin a bit this year.I mean, we're down 54% since the start of 2026. >> We are down quite a bit. And before I get into everything, you know, Jenny, it ...

Core Insights - Brown Capital Management's Small Company Fund underperformed in Q4 2025, with a decline of 1.50% compared to the Russell 2000® Growth index's gain of 1.22% [1] - The Fund's performance for the entire year of 2025 was down 11.46%, significantly lagging behind the Index's return of 13.01% [1] - The Fund's investment strategy is based on company fundamentals, which showed strong revenue and earnings growth in 2025 [1] Company Focus: Veeva Systems Inc. - Veeva Systems Inc. (NYSE:VEEV) is a technology company providing a cloud-based software platform for the life sciences industry, with a market capitalization of $29.64 billion [2] - The stock of Veeva Systems Inc. experienced a one-month return of -19.57% and a 52-week decline of 20.26% [2] - Veeva Systems was identified as a detractor from the Fund's performance in Q4 2025, despite its strong market position and innovative solutions in the life sciences sector [3] - The company's offerings include Veeva Customer Relationship Management (CRM) and Veeva Vault, which have established a dominant market position and present opportunities for growth in clinical applications [3] - Veeva's client base includes major global pharmaceutical companies such as GlaxoSmithKline, AstraZeneca, Eli Lilly, Merck, and Novartis [3]

Core Insights - Gossamer Bio's experimental drug for a serious lung and heart condition failed to meet the primary endpoint in a late-stage clinical trial [1] Company Summary - Gossamer Bio announced the failure of its experimental drug in a late-stage study, which is a significant setback for the company [1]

Company Overview - Generate Biomedicines, a drug developer based in Somerville, Massachusetts, is targeting a valuation of up to $2.17 billion in its upcoming initial public offering (IPO) in the United States [1] - The company is backed by venture firm Flagship Pioneering and aims to raise up to $425 million by offering 25 million shares priced between $15 and $17 each [1] IPO Details - Generate Biomedicines plans to list on the Nasdaq under the symbol "GENB" [1] - The IPO comes as biotech offerings have seen a strong start this year, following a sluggish 2025, attributed to easing interest rates and increased capital inflows into the sector [1] Underwriters - The underwriters for the offering include Goldman Sachs, Morgan Stanley, Piper Sandler, Guggenheim Securities, and Cantor [1]

Novo shares slump after the Danish drugmaker's experimental obesity drug fails to beat Lilly's treatment in an 84-week trial. ...