Nov 25, 2025 9:25 AM Eastern Standard Time Allurion Announces Initial Results on Combining the Allurion Program With Low-Dose Tirzepatide to Optimize Muscle Mass and GLP-1 Adherence Share Average Total Weight Loss of 23% With 14% Increase in Lean Body Mass After 12 Months All patients remained adherent to tirzepatide for the duration of the study NATICK, Mass.--(BUSINESS WIRE)--Allurion Technologies, Inc. ("Allurion†or the "Company†) (NYSE: ALUR), a pioneer in metabolically healthy weight loss, today anno ...

Eli Lilly’s market capitalisation hit the $1tn mark in the past week, becoming the first healthcare company in the world to join the exclusive club dominated by technology companies. Buoyed by unprecedented demand for its weight loss drugs, the US drugmaker hit the trillion-dollar mark for the total value of its shares on 21 November. Share price in Lilly closed at $1,059.70 on 21 November, reflecting a 27% increase since January 2025. By trading at market open 24 November, share prices retreated slightl ...

Core Insights - GLP-1 medicines are experiencing significant growth in the pharmaceutical industry, particularly for weight management, with Eli Lilly and Novo Nordisk as the leading companies [1][6] - Eli Lilly's tirzepatide has rapidly become the world's best-selling drug, generating $24.8 billion in revenue in the first nine months of 2025 [2] - Eli Lilly is advancing its position with additional candidates like orforglipron and retatrutide, which could enhance its competitive edge in the GLP-1 market [4][5] Eli Lilly's Position - Eli Lilly's tirzepatide, marketed as Mounjaro and Zepbound, has cannibalized sales of its previous best-seller, Trulicity, and has shown effectiveness in multiple indications [1] - The drug mimics both GLP-1 and GIP hormones, leading to superior performance in weight management compared to competitors [3] - Eli Lilly has completed phase 3 studies for orforglipron, an oral GLP-1 medicine, which could be a first in the weight management category [4] - Retatrutide, currently in phase 3 studies, mimics three hormones and may further improve treatment efficacy [5] Novo Nordisk's Challenges - Novo Nordisk, previously the market leader, has seen its global market share decline from 55.7% to 49.3% as of August [7] - The company markets semaglutide under well-known brands like Ozempic and Wegovy but is struggling to keep pace with Eli Lilly's advancements [6][7]

Core Insights - Eli Lilly has achieved a market capitalization exceeding one trillion dollars, becoming the first health industry company to reach this milestone [2][4] - The company's growth is primarily driven by the rising demand for weight loss drugs, particularly its offerings tirzepatide, Mounjaro, and Zepbound [5][8] Financial Performance - Eli Lilly's stock price has increased by 35% this year, significantly contributing to its market valuation [5] - In the third quarter, the company generated over $10 billion from its weight loss drugs, which accounted for more than half of its total sales of $17.6 billion during that period [7] - By October, the weight loss drugs had already generated $25 billion in revenue, surpassing the company's total revenue for the entire year of 2020 [8] Competitive Landscape - Eli Lilly is in a competitive race with Novo Nordisk, which is also seeking FDA approval for its oral weight loss drug [9] - Both companies are reducing prices for their injectable weight loss drugs in response to calls from the Trump administration [9][10] - Despite Eli Lilly's success, Novo Nordisk has faced a decline in investor confidence, with its stock value dropping sharply in 2025 [11] Innovation and Future Prospects - Eli Lilly is developing a new oral weight loss drug, orforglipron, which is a candidate for early FDA approval [8] - The company emphasizes a shift in focus from merely delivering medicine to providing personalized and accessible healthcare solutions [13]

By Mrinalika Roy (Reuters) -Eli Lilly hit $1 trillion in market value on Friday, making it the first drugmaker to enter the exclusive club dominated by tech giants and underscoring its rise as a weight-loss powerhouse. A more than 35% rally in the company's ​stock this year has largely been driven by the explosive growth of the weight-loss drug market. In the last two years as new, highly effective ‌obesity treatments hit the market, the category has emerged as one of the most lucrative segments in heal ...

Key Points Eli Lilly's share price now stands above $1,000. The company's outlook through the next few years seems strong. The pharma giant looks likely to conduct a stock split in the (relatively) near future. 10 stocks we like better than Eli Lilly › Eli Lilly (NYSE: LLY) has had a tumultuous year. The pharmaceutical giant lagged the market for much of it, due to worse-than-expected financial results and a clinical setback. However, the Eli Lilly has roared back and is up 32% year to date. The ...

Core Insights - The healthcare sector has significantly outperformed the broader market, with the S&P 500 Healthcare Sector index rising over 6% since mid-October, compared to a mere 0.05% increase in the S&P 500 index [1] Group 1: Performance Drivers - Major pharmaceutical companies like Novo Nordisk and Eli Lilly have positively impacted the sector by securing a deal with the Trump administration, allowing them to avoid tariffs for three years and gain access to Medicare and Medicaid patients for their GLP-1 drugs [3] - Eli Lilly's third-quarter results exceeded Wall Street expectations, leading to a 27% increase in its share price over the past month, significantly influencing the sector's performance due to its large market cap [4] - Pfizer also entered a similar agreement with the White House, resulting in a 4% increase in its stock price over the past month [5] - AbbVie reported strong quarterly results, with a 6% increase in its stock price, and projected significant future revenues for its drugs [6] - Amgen's stock surged nearly 15% after reporting better-than-expected revenue and earnings, with its cholesterol drug showing promising results [7] Group 2: Market Sentiment - There is a noticeable flight to safety among investors, as concerns about market overvaluation grow, leading to increased interest in defensive stocks like healthcare [8] - The healthcare sector, along with consumer staples and energy, has outperformed technology and consumer discretionary sectors, indicating a shift in investor sentiment [9]

Core Insights - Eli Lilly has secured a deal with the Trump administration that could significantly boost its stock value [1][5] - The company’s drug tirzepatide, marketed as Mounjaro and Zepbound, has become the best-selling drug globally, with year-to-date sales of $24.8 billion [2][10] - The agreement will allow Medicare to cover GLP-1 weight loss drugs at discounted prices, expanding access to millions of recipients [6][10] Company Overview - Eli Lilly's current stock price is $1017.78, with a market capitalization of $962 billion and a gross margin of 83.03% [3] - The company leads the weight-loss drug market with a 57% market share, and the market is projected to exceed $200 billion in annual sales by 2031 [10][11] Market Dynamics - The deal with the Trump administration will lower the cash price of Zepbound from approximately $500 to as low as $150 for eligible Medicare recipients [8] - An estimated 1-in-10 Medicare recipients may qualify for the discounted drugs, which could significantly increase the number of prescriptions [6][9] - The overall number of patients starting GLP-1 treatments for non-diabetic purposes has surged by 700% since 2019, indicating a growing market potential [9] Future Prospects - The agreement is expected to enhance Eli Lilly's position in the expanding weight-loss drug market, with additional eligibility for Medicaid recipients anticipated by 2027 [7][10] - The introduction of a new "TrumpRx" website will facilitate access to these medications at reduced prices [8]

Summary of China Obesity KOL Event Industry Overview - The focus is on the **China obesity market**, which is currently **under-penetrated** with significant potential for growth [2][3][6] Key Insights 1. **Market Potential**: The obesity market in China has substantial growth potential due to its current under-penetration [2][3] 2. **GLP-1 Therapies**: The brand value of currently approved **GLP-1 therapies** in China is considered modest, primarily due to their short market presence and high costs, which significantly influence patient adoption [2][3][6] 3. **Patient Demographics**: GLP-1 therapies are mainly utilized by the younger generation (under 40 years old) for cosmetic weight loss rather than for health-related obesity treatment, unless severe comorbidities are present [3][6] 4. **Tirzepatide Uptake**: **Tirzepatide** has shown strong market uptake due to its effective weight loss results and manageable safety profile, with fewer gastrointestinal adverse events reported compared to competitor GLP-1s [2][3][7] 5. **Cost Considerations**: The current price range for GLP-1 therapies is between **RMB 4,000 to RMB 4,500** (approximately **$560 to $630**) per month, with potential for significant price reductions (up to **90%**) upon the entry of generics [6][7] 6. **Oral and Long-acting GLP-1s**: Oral and long-acting GLP-1s are expected to drive market expansion, particularly in less developed regions due to lower supply chain requirements and potentially lower prices [7] 7. **Government Reimbursement**: There is caution regarding government reimbursement for obesity treatments due to high costs, although potential exists if cardiovascular or other comorbidity benefits are recognized [3][6] 8. **Online Purchases**: The popularity of purchasing weight loss drugs online is increasing, although this trend may face regulatory changes if serious adverse events arise [6][7] Additional Considerations - The average treatment duration for GLP-1s in China is currently **2-3 months**, with patients not yet viewing it as a lifelong therapy [7] - The KOL was unaware of a compounded GLP-1 market in China but noted sufficient capacity to significantly lower active pharmaceutical ingredient (API) costs [7] - Direct-to-consumer (DTC) advertising significantly impacts patient preferences, especially when potential benefits on comorbidities are recognized [7] This summary encapsulates the critical insights from the KOL event regarding the current state and future potential of the obesity treatment landscape in China, particularly focusing on GLP-1 therapies and market dynamics.

Core Insights - Earnings season presents opportunities for lesser-known companies to gain attention, with three stocks highlighted for potential comebacks if their earnings reports are favorable [2] Company Overview - Scholar Rock Holding Corp. (NASDAQ: SRRK) is a biotech firm focused on developing protein therapeutics for neuromuscular diseases [3] - The lead asset, apitegromab, targets Type 2 and Type 3 Spinal Muscular Atrophy (SMA) and has shown promising Phase 3 data, indicating strong potential for regulatory approval in 2026 [4] Financial Performance - Scholar Rock's shares have declined approximately 33% year-to-date due to manufacturing site issues, raising short-term concerns [4] - The company is projected to report a loss per share of 76 cents for the third quarter, with no revenue expected yet [6] Clinical Development - A Phase 2 study of apitegromab demonstrated over 54% lean mass preservation compared to control when combined with GLP-1 agonist tirzepatide, indicating the drug's therapeutic promise [5] - Investors should look for updates on apitegromab and other drugs in the pipeline during the upcoming earnings report [6] Market Sentiment - Quarterly earnings reports can significantly impact share prices, with Scholar Rock, along with Globant and NiCE, being identified as companies that may see a rebound if they deliver strong earnings [7]