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复星医药回应“九期一”热议:确证性临床研究获药审中心认可
Core Viewpoint - Fosun Pharma is acquiring a controlling stake in Green Valley Pharmaceutical for approximately RMB 1.412 billion, aiming to integrate its core drug GV-971 into its innovative drug pipeline for Alzheimer's disease treatment [1][2]. Group 1: Acquisition Details - The acquisition involves a combination of "transferring existing equity + subscribing to new registered capital," with Fosun Pharma set to hold 51% of Green Valley's shares [2]. - The total transaction amount of RMB 1.269 billion will be paid in installments, with the first payment of RMB 635 million made on the closing date, and the remaining RMB 634 million to be paid within three years based on the company's R&D progress [2][3]. - The founder-controlled entity of Green Valley will pledge 10% of the company's shares post-acquisition to provide guarantees against potential risks [2]. Group 2: Clinical Trial and Product Development - The acquisition will provide necessary funding for the clinical trials of GV-971 and support its commercialization, including clinical operations, registration, and marketing [3]. - The clinical trial design for GV-971 has been revised to extend the double-blind medication period from 36 weeks to 48 weeks and increase the sample size from 1,312 to 1,950 participants, in accordance with the latest guidelines from the National Medical Products Administration [3][4]. - As of December 15, 2025, 580 participants have been enrolled in the clinical study, with completion of enrollment expected by the end of 2027 and data readout anticipated in early 2029 [4]. Group 3: Strategic Positioning - Fosun Pharma has been focusing on the central nervous system degenerative disease sector, enhancing its product portfolio with a collaborative innovation model that includes both drugs and devices [4][5]. - This acquisition represents a strategic move to address unmet clinical needs in the treatment of Alzheimer's disease, further enriching the company's innovative product pipeline and market positioning [5].
复星医药 (02196) 回应收购绿谷医药:甘露特钠胶囊确证性临床研究获药审中心认可,已累计入组580例
Zhi Tong Cai Jing· 2025-12-23 01:15
Core Viewpoint - Fosun Pharma has announced a strategic acquisition of 51% stake in Green Valley Pharmaceutical, aimed at enhancing its capabilities in the Alzheimer's disease treatment sector and ensuring funding for clinical trials of the drug Ganluo Sodium Capsule [1][3]. Group 1: Acquisition Details - The acquisition will be executed through a combination of "acquiring existing equity + subscribing to new registered capital," with a total payment of 1.269 billion yuan, structured in installments [1]. - The first payment of 635 million yuan will be made on the closing date, while the remaining 634 million yuan will be paid within three years based on the clinical progress of the target company [1]. - The founder-controlled entity of the target company will pledge 10% of its shares post-acquisition to provide collateral against potential risks [1]. Group 2: Clinical Trial Progress - Fosun Pharma has revised the post-marketing confirmatory clinical trial protocol for the Alzheimer's drug, extending the double-blind treatment period from 36 weeks to 48 weeks and increasing the sample size from 1,312 to 1,950 participants [2]. - As of December 15, 2025, a total of 580 participants have been enrolled in the clinical study, with completion of enrollment expected by the end of 2027 and data readout anticipated in early 2029 [2]. Group 3: Strategic Focus - Fosun Pharma is committed to the field of neurodegenerative diseases, enhancing its product portfolio with a collaborative innovation model that includes both drugs and medical devices [3]. - The acquisition is part of the company's strategy to address unmet clinical needs in this therapeutic area and to further enrich its pipeline of innovative products [3].
复星医药(02196)回应收购绿谷医药:甘露特钠胶囊确证性临床研究获药审中心认可,已累计入组580例
智通财经网· 2025-12-23 00:12
Core Viewpoint - Fosun Pharma is acquiring a 51% stake in Green Valley Pharmaceutical through a combination of stock transfer and capital subscription, with a total investment of 1.269 billion yuan, structured to manage clinical and investment risks effectively [1] Group 1: Acquisition Details - The acquisition involves a phased payment structure, with an initial payment of 635 million yuan at the time of closing and the remaining 634 million yuan to be paid within three years based on the company's subsequent R&D progress [1] - The founder-controlled entity of the target company will pledge 10% of its shares post-acquisition to provide collateral against potential risks [1] Group 2: Clinical Development Progress - Fosun Pharma is revising the post-marketing confirmatory clinical trial protocol for its Alzheimer's drug, extending the double-blind treatment period from 36 weeks to 48 weeks and increasing the sample size from 1,312 to 1,950 participants [2] - As of December 15, 2025, 580 participants have been enrolled in the clinical study, with full enrollment expected by the end of 2027 and data readout anticipated in early 2029 [2] Group 3: Strategic Focus - Fosun Pharma is enhancing its product portfolio in the field of neurodegenerative diseases, having developed a collaborative innovation model that includes both drugs and devices [3] - The acquisition is part of the company's strategy to address unmet clinical needs in this therapeutic area and to further enrich its pipeline of innovative products [3]
复星医药回应收购绿谷医药:甘露特钠胶囊确证性临床研究获药审中心认可,已累计入组580例
Zhi Tong Cai Jing· 2025-12-23 00:11
Core Viewpoint - Fosun Pharma is acquiring a 51% stake in Green Valley Pharmaceutical through a combination of stock transfer and capital subscription, with a total investment of 1.269 billion yuan, structured to manage clinical and investment risks effectively [1][2]. Group 1: Acquisition Details - The acquisition involves a phased payment structure, with an initial payment of 635 million yuan at the time of closing and the remaining 634 million yuan to be paid within three years based on the company's R&D progress [1]. - The founder of the target company will pledge 10% of the company's shares post-acquisition to provide collateral against potential risks [1]. Group 2: Clinical Development - Fosun Pharma is committed to funding the clinical trials for the drug Ganluo Sodium Capsule, which will also be integrated into its innovative drug pipeline [1]. - The clinical trial for Alzheimer's disease has been revised to extend the double-blind medication period from 36 weeks to 48 weeks and increase the sample size from 1,312 to 1,950 participants, in line with the latest regulatory guidelines [2]. Group 3: Strategic Focus - Fosun Pharma is enhancing its product portfolio in the field of neurodegenerative diseases, aiming to address unmet clinical needs and strengthen its market position through a collaborative innovation model that includes both drugs and medical devices [3].
复星医药拟14.12亿元接盘绿谷医药,净资产1036万元!郭广昌图的啥?公司今年因行贿医被罚款
Xin Lang Cai Jing· 2025-12-16 02:04
Core Viewpoint - Fosun Pharma plans to acquire Green Valley Pharmaceutical for 1.412 billion yuan, despite the latter's net assets being only 10.36 million yuan. The acquisition aims to integrate Green Valley's core product, Manzot sodium capsules, into Fosun's innovative drug pipeline for treating mild to moderate Alzheimer's disease [1][17]. Group 1: Acquisition Details - The acquisition will make Green Valley a subsidiary of Fosun Pharma, enhancing its product offerings in the central nervous system treatment area [1][11]. - The core product, Manzot sodium capsules, received conditional approval from the National Medical Products Administration in November 2019 and was included in the national medical insurance catalog in 2021 [1][17]. - Due to the expiration of the registration certificate, commercial production of the product will not resume until after November 2024, pending the completion of post-marketing confirmatory clinical trials [1][17]. Group 2: Financial Performance - In 2023, Green Valley reported revenues of 378 million yuan, with a pre-tax loss of 9.81 million yuan and a net profit of 31.48 million yuan [2][18]. - For 2024, the company expects revenues to rise to 572 million yuan, with a pre-tax profit of 70.77 million yuan and a net profit of 70.77 million yuan [2][18]. - However, in the first nine months of 2025, revenues dropped to 102 million yuan, with a pre-tax and net loss of 67.61 million yuan [3][19]. Group 3: Operational Challenges - Since May 2023, Green Valley has faced supply issues with Manzot sodium capsules, leading to reports of drug shortages and rising prices [4][20]. - The company has been under significant operational pressure, with tight cash flow reported [4][20]. - Green Valley was fined 400,000 yuan for commercial bribery related to the promotion of its drug [5][21]. Group 4: Company Overview - As of September 30, 2025, Green Valley's total assets were 806 million yuan, with total liabilities of 795 million yuan, indicating a precarious financial position [4][20]. - The company is primarily focused on cognitive health solutions and has plans to expand its product pipeline beyond Manzot sodium [1][27].
复星医药拟14亿元控股绿谷医药 后者核心产品已停产1年
Core Viewpoint - Fosun Pharma plans to invest 1.412 billion yuan to acquire a controlling stake in Green Valley Pharmaceutical, aiming to enhance its product pipeline in the central nervous system degenerative disease sector [5] Group 1: Acquisition Details - The acquisition will be executed through purchasing existing shares from original shareholders and subscribing to newly registered capital, resulting in Fosun Pharma holding 51% of Green Valley Pharmaceutical [5] - Green Valley Pharmaceutical's assessed valuation is 1.674 billion yuan [5] Group 2: Product Information - Green Valley Pharmaceutical's main product is the mannitol sodium capsule for treating Alzheimer's disease, which has been suspended from production since November 2024 due to the expiration of its registration certificate [5][6] - The product was conditionally approved for market entry in November 2019 and included in the national medical insurance drug list in 2021 [5] Group 3: Financial Performance - Green Valley Pharmaceutical reported owner equity of 22.98 million yuan in 2023, -16.43 million yuan in 2024, and 10.36 million yuan as of September 30, 2025 [6] - The company achieved revenues of 378 million yuan in 2023, 572 million yuan in 2024, and 102 million yuan in the first nine months of 2025, with a net profit of 31.48 million yuan in 2023, 70.77 million yuan in 2024, and a loss of 67.61 million yuan in 2025 [6] Group 4: Operational Challenges - Green Valley Pharmaceutical faced operational challenges, including the closure of its office and production areas related to the mannitol sodium capsule in June 2025 [7] - The company was fined 400,000 yuan for illegal kickback practices aimed at increasing drug sales, involving 587 academic meetings and significant financial misconduct from July 2022 to July 2024 [7][8]
复星医药:拟出资14.12亿元投资绿谷医药 加码布局中枢神经系统领域创新药管线
Zhong Zheng Wang· 2025-12-15 12:00
Core Viewpoint - Fosun Pharma is investing 1.412 billion yuan to acquire a controlling stake in Green Valley Pharmaceutical, which focuses on the research, production, and sales of drugs for neurodegenerative diseases, particularly Alzheimer's disease [1][2]. Group 1: Investment Details - The acquisition will make Green Valley Pharmaceutical a subsidiary of Fosun Pharma [1]. - Green Valley's main product, Ganluo Sodium Capsule, received conditional approval from the National Medical Products Administration in November 2019 for treating mild to moderate Alzheimer's disease [1]. - The product is included in the national medical insurance directory as of 2021 [1]. Group 2: Financial Performance - In 2024, Green Valley is projected to achieve revenue of 572 million yuan and a pre-tax profit of 70.77 million yuan [2]. - From January to September 2025, Green Valley is expected to generate revenue of 102 million yuan but will incur a pre-tax loss of 67.61 million yuan due to the expiration of the original registration certificate [2]. Group 3: Strategic Focus - The investment is part of Fosun Pharma's strategy to enhance its presence in the central nervous system treatment sector, addressing unmet clinical needs in neurodegenerative diseases [3]. - The company plans to support the post-marketing confirmatory clinical trials for Ganluo Sodium Capsule to expedite its approval process [3]. - Fosun Pharma is also exploring a multi-technology approach to treatment solutions, including non-invasive diagnostic equipment and new oral drugs for Alzheimer's disease [3].