Workflow
多组学融合
icon
Search documents
中国学者连发4篇Cell论文,登上Cell期刊封面
生物世界· 2025-07-11 08:40
Core Insights - A significant collaborative research effort involving over 300 scientists from more than 30 institutions has published 10 papers on brain mapping in top-tier journals such as Cell and its sub-journals [2][3] Group 1: Research Findings - The studies reveal various cell types and their connections in the brains of mice and primates, with a notable cover image depicting a macaque gazing at a starry universe, symbolizing the brain's complexity [5] - The first multimodal atlas of the macaque claustrum has been created, identifying 48 cell types through single-nucleus RNA sequencing, highlighting the unique cell types in macaques compared to other species [6][7] - The research integrates single-cell transcriptomics, spatial data, and connectivity analysis, providing a comprehensive understanding of the claustrum's role as an "information hub" in the brain [8] Group 2: Methodological Innovations - A new high-speed imaging technique has been developed for whole-mouse peripheral nerves at subcellular resolution, allowing for unprecedented 3D mapping of the peripheral nervous system [16][20] - This technique enables the visualization of sensory and motor projections, revealing intricate structural features and pathways of the vagus nerve [20][21] Group 3: Implications for Future Research - The identification of cell type-specific enhancers in the macaque brain offers new tools for monitoring and manipulating neuronal activity, advancing the understanding of primate brain structure and cognitive principles [24][28] - The advancements in brain mapping technologies are expected to facilitate research into brain diseases and inspire developments in artificial intelligence systems [30]