Core Insights - Chinese scientists have made significant progress in brain mapping research, with 10 studies published in international journals, including "Cell" and "Neuron," showcasing advancements in understanding brain structure and function [1][2][3] Group 1: Research Achievements - The "Whole Brain Mesoscopic Neural Connectivity Atlas" project aims to create detailed brain maps of non-human primates and humans, addressing the complexity of mammalian brains, which contain nearly 100 billion neurons and over 100 trillion connections [2][3] - A team of over 300 researchers from more than 30 institutions has successfully completed studies that analyze brain cell diversity, connectivity patterns, and molecular mechanisms of brain diseases, enhancing China's international influence in this field [2][3][6] - The research includes the first high-resolution evolutionary atlas of 1.3 million brain cells from various species, revealing key gene evolution related to differences in brain cell types across species [3][12] Group 2: Technological Innovations - The development of specific genetic tools for primate brain research allows for precise delivery of functional proteins to targeted cells, potentially enabling targeted therapies for brain diseases [4][5][25] - A new collection of tools for specific labeling and observation of primate brain cells has been established, marking a significant advancement in understanding brain structure and diseases [4][25][30] Group 3: Collaborative Efforts - The establishment of the "International Primate Mesoscopic Brain Atlas Alliance" aims to enhance global collaboration in brain mapping research, with a focus on creating a shared database for brain atlas data [9][32] - The research integrates contributions from various international institutions, highlighting the collaborative nature of modern neuroscience research [9][32] Group 4: Future Directions - The goal is to complete the mesoscopic neural connectivity atlas for mice by 2025 and for macaques by 2035, indicating a long-term commitment to advancing brain mapping technologies [8][9] - Continued development of imaging and labeling technologies is essential for achieving high-quality brain maps, which are crucial for understanding complex brain functions [14][15]

Core Insights - A significant collaborative research effort involving over 300 scientists from more than 30 institutions has published 10 papers on brain mapping in top-tier journals such as Cell and its sub-journals [2][3] Group 1: Research Findings - The studies reveal various cell types and their connections in the brains of mice and primates, with a notable cover image depicting a macaque gazing at a starry universe, symbolizing the brain's complexity [5] - The first multimodal atlas of the macaque claustrum has been created, identifying 48 cell types through single-nucleus RNA sequencing, highlighting the unique cell types in macaques compared to other species [6][7] - The research integrates single-cell transcriptomics, spatial data, and connectivity analysis, providing a comprehensive understanding of the claustrum's role as an "information hub" in the brain [8] Group 2: Methodological Innovations - A new high-speed imaging technique has been developed for whole-mouse peripheral nerves at subcellular resolution, allowing for unprecedented 3D mapping of the peripheral nervous system [16][20] - This technique enables the visualization of sensory and motor projections, revealing intricate structural features and pathways of the vagus nerve [20][21] Group 3: Implications for Future Research - The identification of cell type-specific enhancers in the macaque brain offers new tools for monitoring and manipulating neuronal activity, advancing the understanding of primate brain structure and cognitive principles [24][28] - The advancements in brain mapping technologies are expected to facilitate research into brain diseases and inspire developments in artificial intelligence systems [30]

Core Viewpoint - The collaborative research led by Chinese institutions and international scientists has achieved significant advancements in brain mapping at single-cell resolution, marking a leap from rodent to primate studies, with ten important results published in a special issue of the journal "Cell" [1] Group 1 - The series of results covers key species including reptiles, birds, rodents, non-human primates, and humans, expanding the international brain atlas in terms of cross-species comparison and spatiotemporal dynamics [1] - Unlike previous breakthroughs that focused on isolated points, this series of findings is expected to facilitate a transition from structural to functional research, providing new perspectives and critical tools for understanding the brain [1]

Core Viewpoint - The collaboration between Chinese research institutions and international scientists has achieved significant advancements in brain mapping at single-cell resolution across various species, with ten important results published in the Cell series journals [1] Group 1: Research Achievements - The research covers key species including reptiles, birds, rodents, non-human primates, and humans, expanding the international brain atlas in terms of cross-species comparison and spatiotemporal dynamics [1] - Chinese scientists have created the world's first whole-brain connectivity map of non-human primate prefrontal cortex at single-neuron resolution [1] - The most comprehensive whole-brain connectivity map of the non-human primate striatum has been developed [1] - A single-cell resolution spatial transcriptome map of the hippocampus in both normal individuals and Alzheimer's disease patients has been produced for the first time [1] Group 2: Implications for Understanding Brain Function - These advancements will provide crucial support for understanding the mechanisms of brain function [1]

Market Performance - The Shanghai Composite Index experienced slight fluctuations, closing up 0.18% at 3461.15 points, while the Shenzhen Component Index rose 1.17% to 10534.58 points, and the ChiNext Index increased by 1.9% to 2164.09 points [1] - The total trading volume in the Shanghai and Shenzhen markets was 13336 billion, a decrease of over 700 billion compared to the previous day [1] - The pharmaceutical sector showed strong performance, with gains in home appliances, automotive, electricity, brokerage, and real estate sectors [1] Coal Industry Insights - Coal prices are gradually stabilizing after a period of decline, with domestic coal production growth slowing down since May and power demand turning positive [2] - Citic Securities indicates that coal prices are expected to rise slightly after hitting a bottom, with potential for further increases in the dividend index and leading coal companies [2] - The recommendation is to strategically invest in dividend-leading stocks and undervalued assets within the coal sector [2] Regulatory Developments - The Ministry of Industry and Information Technology is addressing low-price disorder in the photovoltaic industry to promote sustainable development and enhance product quality [3] - The National Medical Products Administration is expediting the release of standards for high-end medical devices, including exoskeleton robots and imaging equipment [3] Food Industry Update - D-Allulose has been approved as a new food ingredient in China, which may lead to increased downstream demand and accelerated capacity release for companies involved in its production [2] Medical and Technology Innovations - The National Medical Products Administration is enhancing regulation of botulinum toxin to prevent illegal distribution, ensuring public safety in drug use [4] - Chinese scientists have made significant advancements in brain mapping, achieving precise mapping of mouse brain regions, which could aid in brain science research [4] - BOE Technology Group has collaborated with Honor to develop a new lightweight flexible OLED folding screen solution for the Honor Magic V5 smartphone [4]

Group 1 - The Chinese Ministry of Commerce expressed a consistent and clear stance on the potential visit of a U.S. business delegation to China, emphasizing mutual respect and cooperation to enhance Sino-U.S. economic relations [2] - Siemens confirmed that the U.S. government has lifted the licensing requirements for exporting chip design software to China, allowing full access for Chinese customers to their software and technology [2] - The Ministry of Commerce reported that China's service trade grew steadily in the first five months of 2025, with total service trade reaching 32,543.6 billion yuan, a year-on-year increase of 7.7% [3] Group 2 - The Ministry of Industry and Information Technology held a meeting focusing on accelerating the high-quality development of the photovoltaic industry, addressing issues of low-price competition and promoting the exit of outdated capacity [3] - The Tianjin Municipal Government is soliciting opinions on a plan to enhance the development of new productivity through technology finance, aiming to support 300 companies in listing and establishing a reserve of 100 technology firms with listing potential [4] - Chinese scientists made a breakthrough in brain mapping research, successfully creating a three-dimensional brain region and stereotactic atlas with a resolution of 1 micron, providing a key tool for neuroscience [4] Group 3 - The National Medical Products Administration announced measures to optimize the lifecycle supervision of high-end medical devices, supporting the rapid market entry of innovative medical devices with significant clinical value [5] - The U.S. Department of Labor reported that the non-farm employment population in June increased by 147,000, significantly exceeding expectations, while the unemployment rate unexpectedly dropped to 4.1% [5] Group 4 - Li Lecheng, Minister of Industry and Information Technology, emphasized the need for comprehensive governance of the photovoltaic industry to promote sustainable development [3] - Huazhong Steel received a stake increase from Xintai Life Insurance, raising its holding to 5% [7] - China Merchants Bank has been approved to establish a financial asset investment company with a registered capital of 15 billion yuan [15]

Core Viewpoint - Chinese scientists have made significant progress in the field of brain mapping, successfully creating a three-dimensional brain region and stereotaxic atlas of mice, which provides a crucial tool for unraveling the mysteries of brain science [1] Group 1 - The research was published in the journal "Nature" on July 2, highlighting the importance of the findings [1] - The team achieved precise mapping of the brain atlas with an isotropic resolution of 1 micron, marking a breakthrough in brain mapping technology [1] - This advancement is expected to facilitate further research and understanding in the field of neuroscience [1]