Summary of Jiuzhou Pharmaceutical Conference Call Company Overview - **Company**: Jiuzhou Pharmaceutical - **Industry**: CDMO (Contract Development and Manufacturing Organization) Key Points and Arguments Financial Performance - Jiuzhou Pharmaceutical reported a revenue growth of **42%** in the first three quarters of 2025, driven by sales growth and improved gross margins [2][3] - Operating cash flow increased by over **100%**, reaching **1.34 billion RMB**, due to timely collection of payments [2][3] - For Q3 2025, the company achieved a net profit of **220 million RMB**, a **42%** year-on-year increase, attributed to sales growth and higher product margins [3] Market Trends and Industry Outlook - The CDMO industry is expected to rebound starting Q4 2024, influenced by a declining interest rate cycle and improved investment environment [2][7] - Jiuzhou Pharmaceutical's **80%** of orders come from overseas, with strong business certainty from major clients [7] - The Japanese and Korean markets are projected to maintain a growth rate of **30%** over the next 1-2 years, while the U.S. market is expected to see contract amounts grow by over **30%** [2][7] Production Capacity and Utilization - New factory capacity utilization exceeded expectations, with the Taizhou factory operating at near full capacity with **17 projects** simultaneously [2][6] - The company plans to maintain a stable expense ratio for the year, with a slight decrease in R&D expense ratio anticipated [2][14] Product Development and Pipeline - The company has introduced over **30** high-value projects in the formulation sector, with **22** projects in the generic drug pipeline, of which **8** have been approved and **9** submitted for approval [4][9] - The Taizhou factory is expected to start production in November 2025, with an annual capacity of **800 kg**, and **30-40%** of this capacity already has confirmed orders [8] Strategic Initiatives - Jiuzhou Pharmaceutical is focusing on enhancing collaboration with core clients and actively expanding its customer base [2][3] - The company is also pursuing mergers and acquisitions to establish overseas commercial production bases [4][13][16] Challenges and Risks - The raw material prices have seen a decline, but an improvement is expected in Q4 2025 [4][15] - The company faces challenges in the raw material sector due to domestic overcapacity and intense competition, leading to price fluctuations [15] Future Plans - Capital expenditure for 2025 is projected to be controlled within **1 billion RMB**, with a focus on talent acquisition in emerging fields such as peptides and small molecules [17] - Jiuzhou Pharmaceutical aims to establish high-automation overseas commercial bases, with an estimated project scale of **100 million USD** [20] Asset Impairment - The company anticipates no significant changes in asset impairment for 2025, maintaining overall stability [21] Additional Important Information - Jiuzhou Pharmaceutical has established a strong presence in the Japanese market, being a core supplier to over half of the top ten pharmaceutical companies [13] - The company is actively working on expanding its capabilities in the peptide and small nucleic acid sectors, with plans for mid-scale production capacity [8][12]

Core Viewpoint - The company reported significant revenue and profit growth for 2024 and Q1 2025, indicating strong operational performance and market demand for its products [1][2]. Financial Performance - In 2024, the company achieved revenue of 1.625 billion yuan, a year-on-year increase of 57.21%, and a net profit attributable to shareholders of 404 million yuan, up 148.19% [1]. - For Q1 2025, the company reported revenue of 566 million yuan, a growth of 58.96%, and a net profit of 153 million yuan, reflecting a 130.10% increase [1][2]. - The gross margin for 2024 was 67.68%, an increase of 6.71 percentage points, while the net profit margin was 24.61%, up 8.60 percentage points [2]. Product and Market Development - The company's self-selected products, including peptides, oligonucleotides, and formulations, showed robust growth, with revenue from self-selected products reaching 1.129 billion yuan, a 79.49% increase [4]. - Strategic collaborations have been established for various innovative drug raw materials and formulations, enhancing market presence and growth potential [4]. - The company is expanding its production capacity, with new facilities expected to contribute significantly to output in the coming years [4]. CDMO Business - The CDMO segment generated revenue of 494 million yuan in 2024, a 22.34% increase, with large orders being progressively delivered [5]. - Long-term contracts with major pharmaceutical companies, including a $100 million contract with a European firm, have commenced delivery, indicating strong demand for CDMO services [5]. Future Projections - Revenue forecasts for 2025-2027 are projected at 2.276 billion yuan, 3.218 billion yuan, and 4.576 billion yuan, with growth rates of 40.06%, 41.42%, and 42.19% respectively [5]. - Net profit estimates for the same period are 559 million yuan, 755 million yuan, and 1.027 billion yuan, with growth rates of 38.20%, 35.09%, and 36.02% respectively [5].

Core Insights - The company reported a strong recovery in revenue and profit growth in the first quarter, with a focus on its unique CRDMO business platform [1][3] - The company achieved a revenue of 9.655 billion yuan, with a year-on-year growth of 23.1% in its continuing operations [1] - The company’s net profit attributable to shareholders increased by 89.06% year-on-year, reaching 3.672 billion yuan [3] Revenue Breakdown - Chemical business generated 7.391 billion yuan in revenue, a year-on-year increase of 32.87% [1] - Testing business revenue was 1.292 billion yuan, showing a decline of 4.04% [1] - Biological business revenue reached 608 million yuan, with a growth of 8.25% year-on-year [1] Regional Performance - Revenue from U.S. clients was 6.38 billion yuan, up 28.4% year-on-year [1] - Revenue from European clients was 1.3 billion yuan, reflecting a growth of 26.2% [1] - Revenue from Chinese clients was 1.53 billion yuan, showing a slight decline of 1.3% [1] - Revenue from other regions was 450 million yuan, with a growth of 3% [1] Order Backlog and Growth Potential - The company’s order backlog for continuing operations reached 52.33 billion yuan, a year-on-year increase of 47.1% [4] - TIDES business orders grew by 105.5% year-on-year, indicating strong demand in the peptide sector [4] - The TIDES business revenue reached 2.24 billion yuan, with a remarkable growth of 187.6% [4] Strategic Insights - The company’s integrated "end-to-end" CRDMO business model has shown significant effectiveness, particularly in the chemical sector [2] - The growth in clinical and commercialization projects has led to improved capacity efficiency [2] - The demand for peptides is expected to continue rising, with the company planning to increase its solid-phase synthesis reactor capacity to 100,000L by the end of 2025 [4]