今日（7.23），港药继续飘红，可T+0交易的恒生生物科技ETF(513280)盘中大涨2%，现仍涨0.84%！资金面上，已连续 两日获资金净流入！值得注意的是，恒生生物科技ETF(513280)是同指数年内唯一净流入的ETF！ | 30સ્ત્ર 综合屏 F9 前复权 超级零加 画线 工具 © ② ાટસ્પ્ | = | | | 恒生生物科技ETF 1 | | 513280 | | --- | --- | --- | --- | --- | --- | --- | | RETF 2025/07/23 收 1.202 幅0.84%(0.010) 开 1.201 高 1.217 低 1.190 均四 | | | | .202 | | +0.010 +0.84% | | MA20 1.0951 MA60 0.9911 MA120 0.8941 MA250 0.7701 | | | (63日) / 63日) | SSE CNY 10:51:19 交易中 | | T+0 / 0 + | | .227 | | | | 净值走势 | | 汇添量恒生生物科技ETF | | 1.20 | | | | 委北 | -13.48 ...

智通财经APP获悉，CRO概念股早盘走强，截至发稿，方达控股(01521)涨14.49%，报1.58港元；康龙化 成(03759)涨7.9%，报19.4港元；金斯瑞生物科技 (01548)涨7.17%，报18.24港元；昭衍新药(06127)涨 7.06%，报22港元；凯莱英(06821)涨4.08%，报98.15港元；药明生物(02269)涨3.21%，报28.9港元。 中泰证券指出，7月10日，CRO、CDMO龙头公司药明康德及博腾股份发布中报业绩预告，其中药明康 德2025年上半年经调整归母净利润约63.1亿元，同比增长44%。该行认为CRO、CDMO板块自2024Q4海 外降息周期开启带来投融资逐步恢复、2025Q2地缘谈判带来悲观预期改善、2025年以来国内创新药大 型BD落地及重磅政策出炉等多重推动下需求端呈逐步恢复态势，叠加过去三年供给端持续出清，板块 有望迎来盈利与估值同时提升的"戴维斯双击"，建议重点布局相关投资机会。 消息面上，美东时间周二，海外CRO企业Medpace股价跳空高开逾44%，早盘涨幅一度扩大到62.3%， 后涨幅有所收窄，收涨近54.7%，创收盘最高纪录，并创上市将近九年来 ...

证券研究报告 | 公司深度报告 2025 年 07 月 17 日 普洛药业（000739.SZ）CDMO 四问四答 华丽蜕变，跻身国内 CDMO 头部梯队 消费品/生物医药 我们曾于 2021 年发布《三问普洛药业 CDMO：结构、兽药、优势》，时隔四 年，我们再用四问四答更新普洛药业 CDMO 业务近年进展，并看好公司 CDMO 业务的高潜力驱动公司持续发展。 强烈推荐（维持） 目标估值：NA 当前股价：14.8 元 基础数据 | 总股本（百万股） | 1158 | | --- | --- | | 已上市流通股（百万股） | 1158 | | 总市值（十亿元） | 17.1 | | 流通市值（十亿元） | 17.1 | | 每股净资产（MRQ） | 6.0 | | ROE（TTM） | 14.8 | | 资产负债率 | 44.9% | | 主要股东 | 横店集团控股有限公司 | | 主要股东持股比例 | 28.3% | 股价表现 % 1m 6m 12m 绝对表现 2 -0 13 相对表现 -2 -6 -1 -20 -10 0 10 20 30 40 Jul/24 Nov/24 Mar/25 Jun/25 ( ...

Market Overview - The A-share market opened slightly lower on July 17 but then experienced a rebound, with all three major indices showing positive performance, particularly the ChiNext index which rose nearly 1% [2] - The total market capitalization reached 14.20 trillion CNY, with a trading volume of 7698.06 million hands and a turnover rate of 1.46% [3] Pharmaceutical Sector - The pharmaceutical sector saw a significant surge, with multiple stocks hitting the daily limit up, including Weikang Pharmaceutical and Chengdu Xian Dao, both reaching a 20% increase [4][5] - Notable stocks in the pharmaceutical sector included: - Chengdu Xian Dao: 21.46 CNY, up 20.02% - Weikang Pharmaceutical: 20.71 CNY, up 19.99% - Other stocks like Lifespring Pharmaceutical and Zhejiang Zhenyuan also saw increases of around 10% [5][6] - The Hong Kong pharmaceutical and biotechnology sector also experienced notable gains, with companies like Fudan Zhangjiang and Kanyin Biotech showing significant price increases [6] Robotics Sector - The humanoid robot concept stocks remained active, with Nanjing Julong hitting the daily limit up of 20%, and other companies like Dongshan Precision and Taijing Technology also seeing substantial gains [7][8] - On July 17, the stock of Aowei New Materials achieved a 20% limit up, marking its seventh consecutive trading day of gains, with a closing price of 27.89 CNY [10][11] Policy Impact - The National Healthcare Security Administration recently announced the initiation of the 11th batch of centralized drug procurement, which will include 55 drug varieties, focusing on mature "old drugs" while excluding innovative drugs from the procurement list [6]

近期CXO及科研服务板块涨幅明显，东吴证券朱国广团队指出，看好该板块主要原因有三：其一业绩 拐点显著。药明康德、博腾股份、纳微科技等纷纷发布Q2业绩预增，尤其是药明康德明显提速。预期 皓元医药、百普赛斯、奥浦迈等也将有不错的业绩；其二国家全面打响反内卷第一枪。光伏、新能源汽 车等已经全面限产，对CXO板块同等受益，利于板块走出低谷；其三中美关系缓和及美联储降息等。4 月中美贸易战受损最大的CXO等出海，谈判后中美关系有所改善利好CXO等；另外美联储降息预期促 使美元指数连续下跌，降息利于一市场融资改善及并购案的加速。 中泰证券认为，从基本面来看，创新药仍是当前医药板块中产业趋势最为明确且具备未来成长空间的子 行业，全年维度创新药作为医药板块的投资主线不会变化，创新药大时代已然到来，建议积极拥抱，加 配医药板块；此外，7月中报业绩预告/快报陆续披露，CRO&CDMO、GLP-1景气赛道、困境反转的原 料药等表现亮眼，建议继续积极布局有望逐步走出拐点的细分板块，如CRO&CDMO、科研上游、特色 原料药等。 天风医药杨松团队更是直言"买全球最好的中国创新药"！杨松认为，立足当下，中国创新药已经凭借坚 实产业基础， ...

Investment Rating - The report upgrades Tigermed-A to Buy from Sell, with target prices increased to Rmb67/HK$73 from Rmb34/HK$37 [3][10] - WuXi AppTec and WuXi Bio are identified as top picks in the CDMO sector, expected to report beats in 1H25 [10][11] Core Insights - The CXO sector in China's healthcare is gaining attention due to improving fundamentals, attractive valuations, and growth in orders backlog [1] - WuXi AppTec is projected to beat its FY25 guidance, supported by strong growth in orders backlog and strategic disposals [2][11] - Tigermed is expected to benefit from innovative drug development and increasing out-licensing activities, leading to stronger revenue growth [3][10] Summary by Sections Top Picks in CDMO Sector - WuXi AppTec and WuXi Bio are favored for their potential to outperform in 1H25, with Tigermed-A also upgraded due to increased clinical trial activities [10] 1H25 Results Preview - WuXi AppTec's 1H25 results are expected to exceed consensus, driven by strong TIDES business and asset disposals [11] - WuXi Biologics and WuXi XDC are also anticipated to report revenue beats [11] Backlog vs. Revenue Growth - WuXi AppTec's backlog growth accelerated to 47% year-on-year in 1Q25, indicating potential revenue growth acceleration [5][48] - Tigermed's backlog grew 12% year-on-year in 2025, suggesting a positive revenue outlook [34] Global Biotech Funding - Overseas innovative drugs' primary market financing rose 28% year-on-year in 2024, with expectations for recovery in 2H25 [44] Company-Specific Insights - WuXi AppTec's management projects revenue to reach Rmb41.5-43.0 billion in 2025, with a focus on profitability improvements [47] - Tigermed is positioned as a key beneficiary of China's drug innovation, with expected revenue growth driven by clinical trial activities [3][10]

Investment Rating - The report maintains a "Buy" rating for Asymchem, Kangji Medical, Weigao, Angelalign, and Hygeia, while Tigermed, WuXi XDC, WuXi Biologics, and Frontage are rated as "Neutral" [11][15][18][27][36]. Core Insights - The report highlights a recovery in the healthcare sector, particularly in the CDMO segment, with expectations for earnings resilience driven by new order growth and demand from both US and EU markets, as well as from Chinese biotech licensing [2][3]. - The Medtech sector is anticipated to see clearer recovery in the second half of 2025, supported by normalized hospital activity and new product contributions [3]. - The report emphasizes the importance of monitoring pricing competition and consumption recovery signals in the services sector, particularly in consumer-related categories [4]. Summary by Sections CRO/CDMO - Earnings are expected to remain resilient, especially for companies with exposure to late-stage development and manufacturing projects [2]. - Key investor focus areas include new order growth, client behavior shifts amid policy uncertainties, and pricing and margin recovery [2][13]. - EPS estimates have been revised upward by an average of 1.3% to 1.4% for 2025-2027, with target prices adjusted by an average of 4% [1]. Medtech - Recovery is expected to materialize more clearly in the second half of 2025, with key areas to watch including the pace of VBP rollout and surgical volume trends [3]. - Companies like Weigao and Kangji are ramping up new product launches and global expansions, despite some tariff-related uncertainties [3]. Services - Reimbursement control and DRG/DIP pressure are likely to persist, impacting pricing and volumes [4]. - The report notes a cautious outlook for M&A activity, with companies like Hygeia becoming more positive while others remain cautious [9]. Financial Estimates - The report provides detailed financial estimates for various companies, indicating expected sales growth and net income projections for FY25 and beyond [14][19]. - For instance, WuXi Apptec is projected to achieve a revenue growth of 10-15% for FY25, while Asymchem anticipates double-digit revenue growth alongside margin improvements [19]. Target Price Changes - Target prices for several companies have been adjusted, with Asymchem's target price increased to HK$85.5, reflecting a 13% change [11][15]. - WuXi Biologics' target price is set at HK$25.6, based on a 12-month forward P/E of 22x [15][31]. Backlog and Order Trajectory - The report includes a detailed analysis of backlog and new order trajectories for key players in the CRO/CDMO space, indicating significant year-on-year growth in sales and backlog for companies like WuXi Apptec and WuXi Biologics [17].

Core Viewpoint - The Hong Kong stock market is experiencing a collective rise, particularly in the innovative drug sector, with leading CXO company WuXi AppTec seeing a significant increase in stock price after its earnings report [1][3]. Group 1: Market Performance - The Hong Kong stock market is showing strong performance, with the innovative drug sector leading the gains, particularly the CXO segment [1]. - WuXi AppTec's stock rose over 13% following its earnings report, contributing to the overall strength of the CXO sector [1][3]. - The Hong Kong Stock Connect innovative drug ETF (159570) increased by 1.4%, with trading volume surpassing 1.6 billion RMB, and has attracted over 5 billion RMB in the last 60 days [1][3]. Group 2: Company Earnings - WuXi AppTec reported an expected revenue of 20.8 billion RMB for the first half of 2025, representing a year-on-year growth of approximately 20.64% [3]. - The net profit attributable to shareholders is projected to be around 8.561 billion RMB, showing a year-on-year increase of about 101.92% [3]. - Adjusted net profit is expected to be approximately 6.315 billion RMB, reflecting a year-on-year growth of about 44.43% [3]. Group 3: Industry Outlook - According to Fengzheng Securities, the innovative drug sector is expected to enter a new upcycle, driven by the recovery of domestic demand and potential interest rate cuts in the U.S. [4]. - The CDMO sector is anticipated to recover quickly due to its reliance on orders from large overseas pharmaceutical companies [4]. - Guotai Junan Securities indicates that the CDMO industry has reached a bottom and is poised for recovery, with strong performance expected in 2025 [4]. Group 4: Policy and Market Dynamics - The upcoming commercial insurance policy for innovative drugs is expected to open up long-term payment avenues for the sector [7]. - The National Healthcare Security Administration has emphasized comprehensive policy support for innovative drugs, which is likely to enhance their market potential [7]. - The commercial health insurance market in China is projected to grow significantly, with premium income expected to reach 977.3 billion RMB in 2024, a year-on-year increase of 8.2% [7]. Group 5: Investment Opportunities - The Hong Kong Stock Connect innovative drug ETF (159570) has a high concentration in innovative drug companies, with the top ten holdings accounting for nearly 72% of the index [8]. - The ETF has shown a remarkable performance, with a 62.78% increase in the first half of 2025, outperforming other medical indices [8]. - The underlying assets of the ETF are Hong Kong stocks, allowing for T+0 trading, which enhances liquidity for investors [8].

从政策破冰到 CRO 供需重塑，把握预期差带来的布局机会 20250709 摘要 CRO 行业经历产能快速扩张后，面临同质化竞争加剧和盈利能力削弱的 挑战。创新药融资受阻和医药政策变化导致 CRO 企业订单需求降低，行 业正处于艰难的去产能阶段，小型企业面临生存危机，头部企业则通过 结构调整实现转型升级。 国家药品审评中心数据显示，2024 年中国药物临床试验数量同比增长 16%，三期临床试验增速达 31%，反映国内药企在创新药研发后期阶 段加速推进。但 BE 实验占比接近 50%，一期实验占比下降，表明早期 临床试验推动放缓。 CRO 企业人均创收及人均创利在 2023 年至 2024 年均出现下滑，订单 价格下行背景下，大型企业虽未大规模裁员，但仍面临效益压力。头部 公司如昭衍新药、泰格等员工人数保持增长，表明其在价格压力下仍扩 充市场份额。 CDMO 行业中，大单品对业绩拉动显著。新冠药物商业化订单曾对药明 康德、凯莱英和博腾股份等企业业绩有明显推动作用。2021 至 2023 年，这三家公司大订单销售额合计实现 42 亿美元收入，利润达 17 亿美 元。 Q&A 如何看待 CRO 行业的当前发展状况及 ...

CXO 及上游行业观点更新 20250710 摘要 中国生物科技行业投融资在 2024 年经历低迷后，2025 年订单数量显 著增长，国内临床试验项目数量跃居全球第一，显示行业正快速复苏， 为相关股票交易策略提供积极信号。 尽管中国生物科技公司 BD 金额与默沙东等国际巨头相比仍有差距，但 对跨国公司而言，中国项目因交易金额相对较低而具有较高性价比，值 得关注。 药明康德在小分子 CDMO 赛道几乎没有竞争对手，业绩表现良好，但受 中美关系影响，其估值较欧美同行存在折价，艾伯维 BTK 抑制剂伊布替 尼和减肥药替尔泊泰等新项目表现超预期。 药明康德、凯莱英等公司港股折价正在缩小，但康龙化成、泰格医药等 公司折价仍较高。海外收入为主的公司新签订单和利润率恢复良好，但 受中美关系影响，估值存在折价。 CRO 行业利润率在 2021 年达到顶峰后，2023-2024 年下滑严重。临 床前 CRO 公司通过裁员和竞争出清迅速去产能，睿智医药和美迪西等公 司在 2025 年第一季度已实现利润率提升。 Q&A 今年以来中国证监会在支持未盈利企业上市方面有哪些举措？ 今年（2025 年）年初以来，中国证监会表示将更大力度支 ...