华泰研究 中报点评 2025 年 8 月 26 日│中国内地/中国香港 医疗服务 公司 1H25 实现收入/归母净利/扣非归母净利 31.88/6.17/5.66 亿元 （yoy+18.2%/+23.7%/+26.3%），其中 2Q25 实现收入/归母净利/扣非归母 净利 16.47/2.91/2.61 亿元（yoy+26.9%/+33.9%/+34.3%），医药行业筑底 回暖背景下，公司业绩持续提速。截至中报披露日，公司在手订单总额 10.88 亿美元，为实现全年业绩的稳健增长奠定基础。考虑行业需求持续回暖，公 司技术工艺行业领先，看好公司 25 年延续向好发展势头。公司 A、H 股均 维持"买入"。 毛利率积极提升，三大费用率同比下降 证券研究报告 凯莱英 (6821 HK/002821 CH) 业绩持续提速，新兴业务亮眼 小分子 CDMO：板块收入稳健增长，海外产能建设积极推进 小分子 CDMO 1H25 收入 24.29 亿元（yoy+10.6%），毛利率 47.8% （yoy+0.6pct），板块发展稳步向前。公司核心业务项目交付能力扎实，1H25 小分子交付项目数共 329 个，其中商业化、临床 ...

2 0 2 5年8月2 2日，中国香料香精化妆品工业协会（以下简称中国香妆协会）发布了一项备受关 注的调研结果——2 0 2 4年度化妆品原料企业3 0强。 这份调研结果之所以备受关注，一方面是因为中国化妆品原料企业，长期以来就像是在没有海 图的海洋中航行。下游品牌方选择供应商时，往往依赖零散口碑或价格高低；企业自身难以客 观定位竞争力；政策制定者也缺乏行业全景视图。整个生态，存在大量信息不对称。 另一方面是因为随着行业的发展，越来越多的人开始意识到原料创新的重要性，并将其视为化 妆品产业的"芯片"。在不少业内人士看来，中国香妆协会发布的这份调研结果实际上是一份洞 察产业核心竞争力的"芯片地图"。 上下滑动查看 那么，这份调研结果究竟是如何产生的，背后有哪些不为人知的故事？揭示了哪些重要的行业 趋势呢？ 中 国 香 妆 协 会 产 业 研 究 中 心 的 调 研 显 示 ， 2 0 2 4 年 中 国 化 妆 品 原 料 市 场 的 规 模 约 为 6 4 4 . 2 9 亿 元。整体呈现出"三大特点"和"三大趋势"。 首先，市场集中度高。 不过值得注意的是，调研结果显示中国化妆品原料市场也正在发生三大趋势性 ...

Summary of the Conference Call for Yaoshi Technology Industry and Company Overview - Yaoshi Technology has been deeply engaged in the molecular building block sector for 19 years, accumulating extensive experience in independent research and patent development, establishing an integrated service system from early research to commercial production [2][5][6] - The core growth point for the company is small molecules, which are essential for new drug development [2][5] Key Points and Arguments - The company has demonstrated excellent performance in cost reduction and efficiency enhancement, with faster delivery speeds and improved service quality, making it difficult for new entrants to penetrate the market [2][8] - In the first half of 2025, the overall revenue of the company grew by 32%, with CDMO (Contract Development and Manufacturing Organization) business increasing by over 60% and order growth approaching 20% [2][11] - The number of phase III and commercial projects increased by 51% year-on-year, indicating a strong pipeline of high-value projects [2][11] - The company expects to adjust its revenue forecast for 2025 to between 1.5 billion to 2 billion, driven by better-than-expected backend revenue and improved capacity utilization [3][13] Future Growth Trends - The backend CDMO business is entering a harvest period, with significant growth expected as commercial projects ramp up [4][12] - By the end of 2025, the company anticipates completing renovations at its Nanjing R&D center, which will alleviate supply-side pressures and restore growth in front-end demand [4] - The company’s integrated service model from research to commercialization is expected to return to a rapid growth trajectory, with net profit anticipated to show significant elasticity in 2026 [4][13] Unique Advantages - Yaoshi Technology has a dedicated information collection team that researches cutting-edge patents globally, allowing the company to provide innovative building blocks to clients [7] - The company’s ability to design, synthesize, and scale building blocks enhances customer dependency and loyalty, creating a competitive edge [7][9] - The proprietary nature of the building blocks, protected by patents, ensures that certain technologies cannot be bypassed, further solidifying the company's market position [9][10] Financial Performance and Projections - The company’s gross margin is expected to recover to between 30% and 35%, with profit elasticity becoming evident as capacity utilization improves [3][13] - The current valuation of the company is considered reasonable but has significant upside potential as order growth accelerates [14] Additional Important Insights - The company has established a comprehensive platform that spans from chemical drug discovery to chemical development and subsequent commercialization [10] - The anticipated increase in capacity utilization and the launch of new projects are expected to enhance profitability and market competitiveness [12][13]

Group 1: Financial Performance - The company achieved a revenue of 920 million yuan in the first half of 2025, representing a year-on-year growth of 23.48% [2] - The net cash flow from operating activities was 467 million yuan, an increase of 240.62% compared to the same period last year [3] - The gross profit margin has shown a slight improvement of 1.4 percentage points from Q1 to Q2, indicating a stabilization trend [3] Group 2: Strategic Focus and Business Development - The company is focusing on three key strategies: concentrating on strategic clients, enhancing technological innovation, and expanding new business growth areas [2] - There has been a 19.88% year-on-year increase in new orders for CDMO business [3] - Revenue from multinational pharmaceutical companies (MNCs) increased by 69.73% year-on-year, reflecting deepening collaborations [3] Group 3: Operational Efficiency and Cost Management - The company is maintaining a capacity utilization rate of 60%-70% in mature workshops, which is considered a reasonable industry level [4] - Cost control measures are being strengthened to balance between cost management and strategic development [3] - The company has implemented various cost-reduction and efficiency-enhancing measures since the second half of last year [5] Group 4: Future Outlook and Market Trends - The company anticipates continued revenue growth in the second half of the year, supported by a favorable order backlog and market demand recovery [4] - There is a plan to expand fixed asset investments to meet the growing demand for new molecular drugs [6] - The company is confident in stabilizing and gradually returning the gross profit margin to an ideal level [5] Group 5: AI and Technological Integration - The company has systematically integrated AI applications across multiple business areas, generating over 80 million novel molecular blocks [10] - AI tools are being utilized to enhance operational efficiency, particularly in project reporting and document processing [10] - Future plans include expanding AI investments and deploying automated laboratory and robotic equipment [10]

Summary of Jiuzhou Pharmaceutical Conference Call Company Overview - **Company**: Jiuzhou Pharmaceutical - **Industry**: Pharmaceutical Contract Development and Manufacturing Organization (CDMO) Key Points CDMO Business Growth - Jiuzhou Pharmaceutical's CDMO business is experiencing steady growth with a rich project pipeline, including 38 projects that have been launched and 90 in Phase III clinical trials, along with over 1,000 projects in Phase I and II [2][4][5] - The company serves over 80 global clients, covering more than 100 active projects, including innovative drugs, generics, and high-barrier formulations [2][4] Emerging Business Segments - Rapid growth in emerging businesses such as peptides and pentavalent vaccines, with over 20 new clients acquired, and orders nearing $10 million [2][6] - Successful delivery of over ten projects in these segments, indicating significant future growth potential [2][6] Generic Drug Business - Steady progress in the generic drug sector, with two specialty raw materials and two generic formulations approved in the first half of the year [2][7] - A total of 22 projects in the generic pipeline, with 8 approved and 9 under review [2][7] Financial Performance - For the first half of 2025, Jiuzhou Pharmaceutical reported revenue of 2.87 billion yuan, a year-on-year increase of 3.86%, and a net profit of 526 million yuan, up 10.7% [3] - The company has strengthened relationships with major clients, particularly in the Japanese and Korean markets, leading to significant project growth [3] Capacity Utilization and Profit Margins - CDMO capacity utilization is steadily increasing, with optimistic gross margin expectations for the next two to three years due to process optimization and a higher proportion of high-value products [2][10] - The gross margin for the first half of 2025 was approximately 41%, with expectations for stability throughout the year [12] New Factory Developments - The new factory in Taizhou has completed validation for five CDM raw material projects and is attracting numerous follow-up projects due to high management standards and successful FDA inspections [2][13] - The factory's capacity utilization is expected to continue increasing in the coming years [13] Market Trends and Client Structure - The client structure remains predominantly large pharmaceutical companies, accounting for 70-75% of business, with significant growth in the U.S. market [14][15] - The company anticipates an increase in collaboration with large pharmaceutical firms, driven by successful partnerships and potential acquisitions of biotech clients [15] Future Plans and Capital Expenditure - Jiuzhou Pharmaceutical plans to enhance global R&D capabilities and expand advanced production capacity, with a multi-functional GMP production line expected to be operational by late 2025 [9][21] - The company has approximately 3 billion yuan in cash reserves for strategic investments and acquisitions [21] International Expansion - The company has made significant inroads into the Japanese market, becoming a supplier for over half of the top ten pharmaceutical companies in Japan, with a growth rate of 30-40% annually [22] - Plans for further expansion into Europe and the U.S. are underway, focusing on small molecule production lines [17] New Product Development - Jiuzhou Pharmaceutical is focusing on new business areas such as small nucleic acids and ADCs, with expectations for significant contributions in the next two to three years [23][24][26] - The company is also expanding its peptide production capacity to meet growing demand, with a new facility set to produce 800 kg annually [25] Overall Confidence - The company expresses strong confidence in continued growth across all business segments, particularly in overseas client expansion and recovery in industry cycles [31]

Core Viewpoint - The company reported significant revenue and profit growth for 2024 and Q1 2025, indicating strong operational performance and market demand for its products [1][2]. Financial Performance - In 2024, the company achieved revenue of 1.625 billion yuan, a year-on-year increase of 57.21%, and a net profit attributable to shareholders of 404 million yuan, up 148.19% [1]. - For Q1 2025, the company reported revenue of 566 million yuan, a growth of 58.96%, and a net profit of 153 million yuan, reflecting a 130.10% increase [1][2]. - The gross margin for 2024 was 67.68%, an increase of 6.71 percentage points, while the net profit margin was 24.61%, up 8.60 percentage points [2]. Product and Market Development - The company's self-selected products, including peptides, oligonucleotides, and formulations, showed robust growth, with revenue from self-selected products reaching 1.129 billion yuan, a 79.49% increase [4]. - Strategic collaborations have been established for various innovative drug raw materials and formulations, enhancing market presence and growth potential [4]. - The company is expanding its production capacity, with new facilities expected to contribute significantly to output in the coming years [4]. CDMO Business - The CDMO segment generated revenue of 494 million yuan in 2024, a 22.34% increase, with large orders being progressively delivered [5]. - Long-term contracts with major pharmaceutical companies, including a $100 million contract with a European firm, have commenced delivery, indicating strong demand for CDMO services [5]. Future Projections - Revenue forecasts for 2025-2027 are projected at 2.276 billion yuan, 3.218 billion yuan, and 4.576 billion yuan, with growth rates of 40.06%, 41.42%, and 42.19% respectively [5]. - Net profit estimates for the same period are 559 million yuan, 755 million yuan, and 1.027 billion yuan, with growth rates of 38.20%, 35.09%, and 36.02% respectively [5].

Investment Rating - The investment rating for the company is "Outperform" (maintained) [1] Core Insights - The company reported a strong recovery in performance with a 10.10% year-on-year increase in revenue for Q1 2025, reaching 1.541 billion yuan, driven by rapid growth in emerging businesses [4][7] - The net profit attributable to shareholders increased by 15.83% year-on-year to 327 million yuan, with a notable 20.14% growth in non-recurring net profit, indicating effective cost management and improved gross margins in emerging businesses [4][7] - Emerging businesses, including peptides and oligonucleotides, showed impressive growth with revenue increasing over 80% and gross margins improving to 33.05% [7] Financial Data and Profit Forecast - Total revenue forecast for 2025 is 6.468 billion yuan, with a projected year-on-year growth rate of 11.4% [6] - The net profit forecast for 2025 is 1.071 billion yuan, reflecting a 12.9% increase compared to the previous year [6] - The company expects to maintain a stable gross margin of around 43.2% in 2025, with a gradual increase in return on equity (ROE) from 6.0% in 2025 to 6.9% in 2027 [6][7]

Investment Rating - The report maintains an "Outperform" rating for the company with a target price of RMB 97.16, compared to the current price of RMB 74.47 [1][10]. Core Insights - The company is experiencing rapid growth in emerging businesses, leading to improved profitability. The focus on polypeptide capabilities and global expansion is expected to drive long-term growth [1][10]. - In Q1 2025, the company reported revenue of RMB 1.54 billion, a 10.10% increase year-on-year, and a net profit attributable to shareholders of RMB 327 million, up 15.83% [10]. - The gross profit margin for Q1 2025 was 42.54%, showing a year-on-year decline of 0.98 percentage points but an increase of 3.28 percentage points quarter-on-quarter [10]. Financial Summary - Revenue projections for 2025-2027 are RMB 6.63 billion, RMB 7.79 billion, and RMB 9.32 billion, respectively, with expected growth rates of 14.2%, 17.5%, and 19.5% [3][5]. - Net profit attributable to shareholders is forecasted to be RMB 1.09 billion in 2025, RMB 1.28 billion in 2026, and RMB 1.53 billion in 2027, reflecting growth rates of 15.1%, 16.8%, and 19.5% [3][5]. - The earnings per share (EPS) for 2025-2027 are projected at RMB 3.03, RMB 3.54, and RMB 4.23, respectively [3][10]. Business Performance - The small molecule CDMO business remained stable, while emerging business revenues grew over 80% year-on-year, with a gross profit margin of 33.05%, up 15.75 percentage points from 2024 [10]. - The company secured a total order backlog of USD 1.052 billion, representing a growth of over 20% year-on-year, ensuring stable revenue growth [10]. - The European R&D and pilot base commenced operations in August 2024, contributing to the expansion of the company's capabilities [10].

Core Viewpoint - 凯莱英 (002821) reported a robust growth in revenue and profit margin for Q1 2025, with a year-on-year revenue increase of 10.1% and a net profit increase of 15.8%, leading to an "overweight" rating from Tianfeng Securities [1][2]. Financial Performance - In Q1 2025, the company achieved a revenue of 1.541 billion yuan and a net profit of 327 million yuan, with gross profit margin and net profit margin at 42.5% and 21.2% respectively [2]. - The net profit growth rate outpaced revenue growth by 5.7 percentage points, indicating effective cost control measures [3]. Cost Control and Efficiency - The company implemented cost reduction and efficiency improvement measures, resulting in a decrease in all expense ratios year-on-year and quarter-on-quarter [3]. - Sales expenses were 44.15 million yuan with a sales expense ratio of 2.9%, down 0.3 percentage points year-on-year and 1.7 percentage points quarter-on-quarter [3]. - Management expenses totaled 184 million yuan with a management expense ratio of 11.9%, down 0.4 percentage points year-on-year and 5.5 percentage points quarter-on-quarter [3]. - R&D expenses were 138 million yuan with a ratio of 8.9%, down 3.2 percentage points year-on-year and 1.1 percentage points quarter-on-quarter [3]. Business Segments - The small molecule CDMO business remained stable with a gross profit margin of 45.17%, and 12 projects expected to reach the PPQ stage in 2025 [3]. - Emerging business revenue grew over 80% year-on-year, with a gross profit margin of 33.05%, indicating a recovery compared to the previous year [3]. - The company plans to add a new OEB5 facility and R&D building to support the growing demand for toxin-linker projects [3]. Employee Incentives - The company launched a restricted stock incentive plan, granting 4.896 million shares at a price of 37.52 yuan per share to 648 individuals, including directors and key personnel [4]. - The plan includes performance-based vesting conditions tied to revenue and profit growth targets from 2025 to 2028 [4]. Profit Forecast and Investment Rating - The company forecasts revenues of 6.617 billion yuan, 7.617 billion yuan, and 8.782 billion yuan for 2025, 2026, and 2027 respectively, with net profits of 1.114 billion yuan, 1.310 billion yuan, and 1.532 billion yuan [5]. - The investment rating remains "overweight" based on the positive financial outlook and growth potential [5].

Investment Rating - The report maintains a "Buy" rating for the company, with a target price set at 74.47 CNY [7][5]. Core Insights - The company reported a revenue of 1.541 billion CNY for Q1 2025, representing a year-on-year growth of 10.1%, and a net profit of 327 million CNY, up 15.8% year-on-year [1]. - The gross profit margin and net profit margin for Q1 2025 were 42.5% and 21.2%, respectively [1]. - The company has implemented cost reduction and efficiency improvement measures, resulting in a net profit growth rate that outpaced revenue growth by 5.7 percentage points in Q1 2025 [2]. - The small molecule CDMO business showed stable performance with a gross margin of 45.17%, while emerging businesses saw revenue growth exceeding 80% and a gross margin of 33.05% [3]. - A stock incentive plan was introduced, granting 4.896 million shares at a price of 37.52 CNY per share, aimed at enhancing employee motivation and company cohesion [4]. Financial Projections - Revenue projections for 2025-2027 are estimated at 6.617 billion CNY, 7.617 billion CNY, and 8.782 billion CNY, respectively [5]. - The expected net profit for the same period is projected to be 1.114 billion CNY, 1.310 billion CNY, and 1.532 billion CNY [5]. - The report anticipates a consistent increase in revenue and net profit margins over the forecast period [5].