C君是一名年轻背包客，他习惯住在景区周边，这样能极大节约游玩时间成本。 01 最近不少计划寒假期间来北京旅游的外地朋友，不约而同地向劲旅君抱怨：北京的酒店怎么这么贵啊？！ A君想要趁着年前拖家带口来北京玩一趟，但在制定旅行计划时就对北京酒店的高价格感到无语。他在OTA上仔细寻摸一圈发现， 但凡是北京知名旅游景点周边，尤其是靠近地铁站的品牌连锁经济型酒店，动辄就七八百一晚起步，稍好一点的品牌连锁中高端酒 店价格直接破千。想要找便宜一点的，要么就是市区二环内不知名的小旅馆，要么只能往远郊区县找品牌连锁经济型酒店，距离市 内核心景区坐地铁都得一两个小时，就这还得四百多一晚。 劲旅君安慰道，或许是因为寒假旅游旺季，北京酒店涨点价格多少能理解。B君却摇头苦笑，这两年非节假日北京酒店的价格也不 见得便宜啊。 为此他在北京的住宿多以青旅为主。只不过他发现，主打廉价的北京青旅现在价格也在悄悄上涨。一个普通床位从原来的60-80元 涨到逼近百元，旺季甚至飙到150元以上。更让他无奈的是，即便频频涨价，北京现存的优质青旅还在不断减少，至少自己这几年 在北京住过的三五家青旅，已经没了一半。 作为资深差旅人士，B君每年频繁赴京出差， ...

Group 1 - The core issue is the severe shortage of the antiviral drug Oseltamivir (Tamiflu) in the U.S. and globally, particularly in cold regions facing high flu activity [1][2][4] - The American Society of Health-System Pharmacists (ASHP) reported that the demand for Tamiflu has surged, with hospital visits for flu-like symptoms reaching the highest level in over 20 years [1][4] - The shortage of Oseltamivir is compared to the scarcity of DDR memory chips, indicating a critical supply-demand mismatch in the pharmaceutical sector [1][2] Group 2 - CVS Health reported a significant increase in demand for Oseltamivir, although it stated that there is not a widespread shortage across the U.S., with some areas experiencing more severe shortages than others [3] - The flu season has been exacerbated by a new variant of the flu virus, known as subclade K, which has led to a notable increase in hospital visits due to flu symptoms [4][5] - The Centers for Disease Control and Prevention (CDC) noted that only 43% of Americans have received the antiviral vaccine, contributing to the severity of the current flu season [4][6] Group 3 - Oseltamivir is classified as a neuraminidase inhibitor, effective in treating Influenza A and B, and is most effective when administered within 48 hours of symptom onset [5][6] - The FDA has approved Oseltamivir for use in individuals aged 2 weeks and older, with an emphasis on early treatment for high-risk populations [6] - Other antiviral medications listed by the CDC include Zanamivir, Peramivir, and Baloxavir, each with different mechanisms of action [6]