Core Viewpoint - The article discusses the increasing interest and cautious use of GLP-1 medications for weight management in the elderly population, highlighting both potential benefits and necessary precautions in their application [4][8][12]. Group 1: GLP-1 Medications in Elderly Care - GLP-1 medications have gained popularity among patients aged 65 and older, with many seeking these treatments for obesity management [4]. - The CDC reports that nearly 40% of individuals aged 60 and above are classified as obese, which significantly impacts their health and quality of life [5]. - Experts emphasize the need for careful evaluation of elderly patients before prescribing GLP-1 medications, particularly for those with frailty or cognitive impairments [8][12]. Group 2: Broader Implications of GLP-1 Medications - Recent studies suggest that GLP-1 medications may have effects beyond glucose control and weight loss, potentially influencing cardiovascular health, addiction behaviors, certain cancers, and cognitive function [6][11]. - In the context of neurodegenerative diseases, GLP-1 medications may help slow cognitive decline due to their anti-inflammatory properties and ability to improve insulin signaling [11]. - Research indicates that patients using GLP-1 receptor agonists have lower all-cause mortality rates compared to those on other diabetes treatments, although the relationship with different cancer types remains unclear [11]. Group 3: Clinical Considerations and Future Research - The complexity of medication decisions for elderly patients necessitates a comprehensive assessment of their overall health, including potential side effects and interactions with other medications [12]. - Experts advocate for a gradual approach to GLP-1 treatment, focusing on maintaining strength, independence, and quality of life rather than solely on weight loss [12]. - There is a recognized need for more representative clinical trial data for older populations, as current studies show that older patients may experience higher rates of discontinuation due to gastrointestinal side effects [12].

步入老年阶段，不少人感到腰酸背痛腿抽筋，还会出现动作变慢等情况。南方医科大学珠江医院康复医 学中心主任吴文介绍："这些都是肢体功能下滑的信号，如果忽视会加速衰退。"吴文说，虽然生理衰老 不可逆，但功能衰退可延缓。老年人增强保养意识，通过健康管理、生活方式干预，有助于延缓肢体衰 老，提升肢体健康。 1.生活规律。 保持睡眠充足、饮食均衡，为肌肉修复与神经稳定打基础。 2.避免累积性伤害。 如何延缓肢体衰老？ 人民日报记者 王云娜 低头刷手机、久坐不动等不良习惯易累积成慢性损伤，可以每30分钟起身活动一下。日常搬重物时，也 应采用正确姿势，避免发力不当对肢体带来伤害。 3.增强基础力量。 肌少症是老年人常见问题，建议每周开展两到三次抗阻训练，比如弹力带练习、坐立起身等。还可以适 当补充蛋白质与钙质，常态化评估肌肉状态。 4.开展平衡训练，预防跌倒。 跌倒是导致老年人住院、卧床乃至生活失能的重要原因之一，往往源于平衡能力下降。可练习单脚站 立、八段锦等，尽可能降低跌倒风险。建议每年开展一次平衡功能评估，若出现问题，应遵医嘱及时进 行康复训练。 5.柔韧拉伸，保持关节灵活。 每日进行10到15分钟的简单拉伸，如靠墙抬 ...

步入老年阶段，不少人感到腰酸背痛腿抽筋，还会出现动作变慢等情况。南方医科大学珠江医院康复医 学中心主任吴文介绍："这些都是肢体功能下滑的信号，如果忽视会加速衰退。"吴文说，虽然生理衰老 不可逆，但功能衰退可延缓。老年人增强保养意识，通过健康管理、生活方式干预，有助于延缓肢体衰 老，提升肢体健康。 1.生活规律。 如何延缓肢体衰老？ 本报记者 王云娜 保持睡眠充足、饮食均衡，为肌肉修复与神经稳定打基础。 2.避免累积性伤害。 低头刷手机、久坐不动等不良习惯易累积成慢性损伤，可以每30分钟起身活动一下。日常搬重物时，也 应采用正确姿势，避免发力不当对肢体带来伤害。 3.增强基础力量。 肌少症是老年人常见问题，建议每周开展两到三次抗阻训练，比如弹力带练习、坐立起身等。还可以适 当补充蛋白质与钙质，常态化评估肌肉状态。 4.开展平衡训练，预防跌倒。 跌倒是导致老年人住院、卧床乃至生活失能的重要原因之一，往往源于平衡能力下降。可练习单脚站 立、八段锦等，尽可能降低跌倒风险。建议每年开展一次平衡功能评估，若出现问题，应遵医嘱及时进 行康复训练。 5.柔韧拉伸，保持关节灵活。 每日进行10到15分钟的简单拉伸，如靠墙抬腿、 ...

Core Viewpoint - By the end of this year, the elderly population aged 60 and above in Guangxi is expected to exceed 10 million, accounting for over 20% of the total population, indicating a transition into a moderately aging society [1] Group 1: Aging Population and Health Management - Guangxi is one of the earliest provinces to enter an aging society and has the largest elderly population [1] - Since the 14th Five-Year Plan, Guangxi has strengthened health management for the elderly, implementing special actions for health promotion and preventive interventions for elderly disabilities and dementia [1] - By the end of 2024, the coverage rate of family doctor contracts for residents aged 65 and above is expected to reach 73.59%, with the elderly health literacy level reaching 11.84%, an increase of 3.67% from 2023 [1] Group 2: Health Service Optimization - A three-year implementation plan for the "Guangxi Silver Age Health Protection Project (2024-2026)" has been jointly issued by multiple departments to address shortcomings in elderly health services [2] - Over 90% of medical institutions in the region have implemented preferential policies for elderly medical services, with 87.9% of hospitals and care facilities becoming age-friendly medical institutions [2] - 94.5% of secondary and higher-level public hospitals have established geriatric departments [2] Group 3: Integrated Medical and Elderly Care Services - The number of integrated medical and elderly care institutions in Guangxi has reached 189, with a total of 48,600 beds and 21,000 service personnel [2] - Four mature service models for integrated medical and elderly care have been formed, including services provided by medical institutions, elderly care institutions, and community-based services [2] - Guangxi promotes the integration of traditional Chinese medicine (Zhuang and Yao medicine) with health and elderly care, establishing 34 demonstration bases for integrated services [2]