Summary of the Conference Call for Lepu Medical Company Overview - **Company**: Lepu Medical - **Industry**: Medical Devices and Pharmaceuticals Key Points and Arguments Traditional Business Performance - Lepu Medical's traditional business remains stable, with cardiovascular devices and generic drugs showing steady performance. The expected profit for the basic business in 2025 is projected to reach between 1 billion to 1.2 billion CNY [2][4][5] - Operating cash flow has significantly improved, reaching 1 billion CNY in the first three quarters, with an annual forecast of 1.5 billion CNY [2][4] Aesthetic Medicine Segment - The aesthetic medicine segment has emerged as a new growth driver, with the "童颜针" (Youthful Needle) achieving nearly 100 million CNY in sales and entering 1,500 to 2,000 institutions [2][5][7] - New products like "热玛吉" (Thermage) and PDRN are expected to launch in the first half of next year, potentially boosting revenue further [2][5][7] Impact of Procurement Policies - The centralized procurement policy has put pressure on cardiovascular devices, but the company is managing dealer inventory and actively participating in procurement to mitigate impacts [2][6] - The coronary cutting balloon may face losses, but the auxiliary balloon is expected to compensate for this, maintaining overall balance [2][6] Market Expansion Strategy - Lepu Medical is aggressively expanding its aesthetic market using a "rural encircling cities" strategy, currently covering 80% of the targeted institutions and planning further expansion through partnerships with platforms like Meituan [2][7][19] Innovation in Drug Development - Significant progress has been made in innovative drug development, with drug 109 completing phase II clinical trials and plans to enter phase III next year. Multiple projects for weight loss, lipid reduction, and blood pressure management are also underway [2][10][11] Financial Performance - In Q3 2025, Lepu Medical reported a nearly 12% year-on-year revenue growth and a 176% increase in net profit, reaching 290 million CNY. Cumulative net profit for the first three quarters was 980 million CNY, slightly exceeding market expectations [3][4] Future Outlook - The company maintains a profit forecast of 1 billion to 1.1 billion CNY for 2025 and anticipates a stable business level in Q4 [4][5] - The aesthetic medicine sector is expected to generate close to 1 billion CNY in sales in 2026, with significant contributions from various products [9][21] Challenges and Opportunities - The aesthetic medicine sector faces challenges due to differing consumer logic and quality demands compared to traditional medical services. However, this also presents opportunities for providing scientifically reliable and easy-to-use products [23][20] Inventory Management - Lepu Medical is actively controlling dealer inventory to minimize stock levels in response to procurement policies, aiming to maintain inventory at one to two months' worth [24][25] Pricing Strategy - Despite recent price reductions by internet platforms, Lepu Medical is committed to maintaining its pricing strategy, offering a multi-tiered pricing approach to cater to different consumer segments [25][26] New Product Development - The company is advancing in the peripheral treatment field with new products like biodegradable occluders, which have shown promising clinical feedback [26][27] Management and Team Stability - The innovative drug team is stable and motivated, with regular clinical meetings and recruitment efforts to strengthen clinical operations [28][29] Conclusion - Lepu Medical is positioned for growth through its stable traditional business, expanding aesthetic medicine segment, and ongoing innovation in drug development, while effectively managing challenges posed by procurement policies and market dynamics. The company’s strategic focus on quality and market expansion is expected to drive future success.

Summary of Haohai Biology Conference Call Company Overview - **Company**: Haohai Biology - **Date**: September 18, 2025 Key Points Industry and Company Performance - **Revenue Decline**: Haohai Biology's revenue for the first half of 2025 decreased by 34% year-on-year, primarily due to changes in VAT policy affecting hyaluronic acid products, resulting in a profit reduction of approximately 30 million yuan [2][3] - **Overall Revenue**: The company achieved a revenue of 1.304 billion yuan in the first half of 2025, a year-on-year decline of 7% but a quarter-on-quarter increase of about 11% [3] - **Net Profit**: The net profit attributable to shareholders was 210 million yuan, down 10% year-on-year, but up 34% quarter-on-quarter [3] Business Segment Performance - **Aesthetic Medicine Segment**: - Revenue decreased by 9% year-on-year, with hyaluronic acid sales down 17% [2][4] - Human epidermal growth factor sales increased by 14% [2] - High-end hyaluronic acid product "Haimi" saw sales growth exceeding double digits, now accounting for over 40% of the segment [2][7] - **Ophthalmology Segment**: - Revenue decreased by 20% year-on-year, but sales of preloaded aspheric intraocular lenses increased by 74% [2][4] - High oxygen permeability orthokeratology lenses saw an 86% increase in sales [2][5] - **Surgical Segment**: - Revenue grew by 60%, with innovative hemostatic product "Kangrui Gel" contributing 44 million yuan [2][5] - New anti-adhesion surgical products performed well, achieving 40 million yuan in sales shortly after launch [2][24] Product Development and Market Strategy - **High-End Product Focus**: The company is focusing on exporting high-end products, with preparations for "Haimi" and "Haimi Yuebai" underway [10] - **New Product Lines**: The company is expanding its aesthetic medicine offerings, including dermal fillers and light therapy devices, with some products receiving FDA certification [11][12] - **Technological Advantages**: "Haimi" utilizes a unique cross-linking process for smooth injection, while "Haimi Yuebai" employs amino acid cross-linking for safety and effectiveness [9] Market Challenges and Responses - **Impact of VAT Policy**: The adjustment of VAT from 3% to 13% on hyaluronic acid and chitosan products is expected to impact profits throughout 2025, but no similar effects are anticipated in 2026 [2][5] - **Competitive Landscape**: The OK lens segment faced challenges due to competition from new products like defocus frame glasses, leading to a decline in sales [20][21] - **Price Pressure**: The company is increasing R&D investment in mid-to-high-end products to counteract potential price pressures from upcoming procurement policies [15] Future Outlook - **Performance Expectations**: The company remains optimistic about future growth despite current economic uncertainties, focusing on steady marketing efforts and product development [26] - **Market Share Potential**: The domestic multifocal intraocular lens market share is expected to increase due to price adjustments in procurement policies [16] Additional Insights - **Sales of Human Epidermal Growth Factor**: This product has seen significant growth due to its application in aesthetic medicine, with sales increasing since 2024 [13] - **Surgical Product Innovations**: The innovative hemostatic product "Kangrui Gel" has entered the Shanghai medical insurance directory, with plans to expand into other provinces [25] This summary encapsulates the key insights from Haohai Biology's conference call, highlighting the company's performance, strategic focus, and market challenges.