Core Viewpoint - The article emphasizes that true aging is not merely the passage of time but the decline of curiosity and the willingness to explore new things, particularly in middle age [3][42]. Group 1: Physical Activity - The article discusses the decline in energy levels as individuals reach middle age, leading to a cycle of lethargy and health issues, such as weight gain and mental fatigue [7][8]. - Engaging in physical exercise is presented as a crucial method to combat these issues, with evidence suggesting that exercise promotes brain health and reduces negative emotions [7][8]. - The narrative includes a personal anecdote about an individual who revitalized their health and career through running, highlighting the importance of maintaining physical activity [7][8]. Group 2: Skill Development - The article points out that many middle-aged individuals become complacent in their careers, failing to develop new skills and thus risking obsolescence in the job market [11][12][13]. - It introduces the concept of the "Thumb Rule," which suggests that lacking a standout skill can lead to being easily replaced in various fields [19][20]. - The article cites the example of a successful individual,冯唐, who continuously learned and adapted across different fields, emphasizing the importance of lifelong learning and skill enhancement [21][23]. Group 3: Open-Mindedness - The article warns against the dangers of closed-mindedness in middle age, where individuals may become rigid in their thinking and resistant to new ideas [27][33]. - It recounts an experience where the author initially dismissed AI writing but later recognized its value, illustrating the need to remain open to new technologies and perspectives [28][30][32]. - The article concludes that maintaining a curious and open mindset is essential for personal and professional growth, allowing individuals to adapt to changes and seize new opportunities [38][40][42].

Core Points - The 2025 Nobel Prize in Chemistry was awarded to Susumu Kitagawa, Richard Robson, and Omar M. Yaghi for their work on metal-organic frameworks (MOFs), which are structures containing large internal cavities that allow molecules to move freely in and out [1] Group 1: Research and Contributions - The research focuses on metal-organic frameworks (MOFs), which are significant for their unique structural properties and potential applications in various fields [1] - Kitagawa's early interest in chemistry was influenced by philosophical ideas from Zhuangzi, leading him to explore the "useless" aspects of organic materials, particularly the tiny pores in these materials [11] - Robson contributed to the development of MOFs while working on a project assigned by his superior, which ultimately led to the discovery of a new type of material with significant internal voids [30][31] - Yaghi, who grew up in a challenging environment, developed MOFs that can capture water vapor from the air, addressing water scarcity issues in arid regions [38][46] Group 2: Personal Backgrounds of the Laureates - Kitagawa is known for his diverse interests, including detective novels and kabuki performances, and emphasizes the importance of public speaking skills among his students [5][6] - Robson has a strong academic background, having studied at prestigious institutions like Oxford and Caltech, and has spent most of his career at the University of Melbourne [13][15] - Yaghi's journey from a refugee background in Jordan to becoming a prominent scientist highlights the transformative power of education and science, as he now supports young scholars in developing countries [35][53]