生物打印
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2026年值得期待的十大技术应用
Ke Ji Ri Bao· 2025-12-04 00:55
Core Insights - The article highlights the rapid advancements in technology expected by 2026, including emotional AI, wearable health devices, renewable energy innovations, and more, which are set to transform daily life and work environments. Group 1: Emotional AI - The next generation of emotional AI assistants is surpassing traditional ones like Siri and Alexa by understanding human emotions through tone, expression, and wording, providing personalized relaxation recommendations and enhancing customer care [2] - Emotional AI is becoming a partner in daily life, playing a significant role in mental health support and personal growth [2] Group 2: Wearable Devices - By 2026, wearable devices are expected to evolve into "life guardians," with smart skin patches monitoring hydration, stress hormones, and nutrition levels, while AI watches can predict heart disease risks days in advance [3] - These innovations are shifting healthcare from reactive treatment to proactive prevention [3] Group 3: Renewable Energy - New night-time solar panels will capture infrared radiation, allowing for continuous power supply even in darkness, while advancements in lithium-sulfur and solid-state battery technologies will enhance energy storage for electric vehicles [4] - 2026 may mark a historical turning point for the decline of fossil fuels as the dominant energy source [5] Group 4: Brain-Computer Interfaces - Brain-computer interface technology is moving from medical applications to everyday use, enabling paralyzed patients to control devices with their thoughts and enhancing work efficiency through instant data retrieval [6] - By 2026, these interfaces will be integrated into daily life, impacting prosthetics, rehabilitation, and augmented reality experiences [6] Group 5: Space Economy - The space economy is set to flourish, with suborbital flight prices dropping below $100,000 and companies developing zero-gravity hotels, indicating a new era of space exploration and commercialization [7] Group 6: AI in Education - AI-driven personalized education is emerging, adapting courses to individual learning styles and helping adults with career transitions, fundamentally reshaping educational approaches [9] Group 7: Quantum Computing - Quantum computing is expected to solve complex problems beyond the capabilities of classical computers, significantly reducing drug development timelines and optimizing supply chains [10] Group 8: Smart Cities - Cities will become smarter by 2026, with AI traffic systems alleviating congestion, IoT-enabled waste management, and predictive security systems enhancing urban living [11] Group 9: Robotics - Robotics will become ubiquitous in households and various work environments, with cooking robots, construction robots, and personal care robots transforming daily tasks [12][13] Group 10: Bioprinting - The bioprinting field is anticipated to achieve significant advancements, enabling the creation of disease models, personalized medicine, and potentially addressing organ donation shortages [14]
杭州师范大学×浙江大学×西湖大学合作Cell子刊:生物打印“会生病”的人工动脉
生物世界· 2025-11-18 04:05
Core Insights - The article discusses a groundbreaking study on cardiovascular disease, highlighting the limitations of existing laboratory models in accurately replicating the complex environment of human arteries [2][5] - The research introduces a novel extrusion-on-demand (EoD) bioprinting technology that creates arterial models with micron-level structural fidelity and customizable macro geometries, enabling better understanding of vascular disease mechanisms and personalized treatment approaches [3][8] Summary by Sections Research Background - Cardiovascular disease is the leading cause of death globally, yet research has been hindered by inadequate laboratory models that fail to replicate the intricate interactions involved in vascular diseases [2] - Current models are either overly simplified (2D) or lack the necessary structural and functional complexity (3D), leading to unresolved mechanisms and ineffective drug trials [2] Technological Innovation - The EoD bioprinting technology developed in this study allows for the construction of arterial models that accurately reflect the microenvironment of vascular diseases, including specific gene/protein expressions that enhance endothelial function and barrier integrity [5][6] - This technology bridges the gap between simplified in vitro systems and the complex in vivo environments, providing a biomimetic platform for disease mechanism analysis and therapy evaluation [5][9] Key Findings - The printed arterial models successfully replicate hallmark processes of vascular diseases, such as endothelial dysfunction, immune cell infiltration, and foam cell formation under physiologically relevant flow and inflammatory conditions [8][9] - The response of these models to drugs mirrors in vivo results, establishing their value for preclinical testing and therapeutic discovery [8] Implications for Future Research - This research not only presents a sophisticated vascular model but also offers a blueprint for engineering complex disease environments, paving the way for decoding vascular disease progression, identifying therapeutic targets, and accelerating precision medicine [9]
耳朵、骨骼、心脏……探秘神奇的“生物打印”
Yang Shi Wang· 2025-09-18 22:47
Group 1: Biomedical Engineering Innovations - Recent advancements in biomedical engineering are reshaping the future of health, with innovations such as 3D printed organs and smart prosthetics [3][12] - In June 2025, a research team in China discovered a "molecular switch" for mammalian organ regeneration, enabling injured adult mice to regrow ear cartilage and nerve tissue [1] - The world's first living heart organoid, over 1 centimeter in diameter, was successfully cultivated in Shanghai, derived from human stem cells, offering new hope for organ transplantation [1][4] Group 2: Organoid Technology and Applications - Organoids are miniaturized organ models created from stem cells that can simulate real organ structures and functions, useful for disease modeling and drug screening [4][11] - The process of 3D printing active organoids requires billions of cells, with advancements in bioprinting technology allowing for the creation of complex structures [5][9] - Current applications include printing skin, cartilage, and small organoids for clinical use, while more complex organ printing is still in research stages [11][12] Group 3: Drug Testing and Personalized Medicine - High-throughput organoid printing technology allows for the simulation of cancer patient tumors, enabling efficient drug testing without the need for blind trials on patients [14] - This method allows for simultaneous testing of multiple drugs and dosages, streamlining the process of finding effective treatment options [14] Group 4: Cross-Disciplinary Collaborations - Recent developments in vision prosthetics demonstrate the potential of interdisciplinary collaboration, with a team creating a wide-spectrum visual prosthetic that enables blind animals to perceive infrared light [17][18] - The project involved multiple national key laboratories, showcasing a new paradigm of innovation in biomedical engineering through cross-laboratory cooperation [24] Group 5: Strategic Industry Development - Shanghai has initiated an innovation ecosystem for organoids since 2021, focusing on drug screening and personalized medicine [26] - Hubei aims to grow its biopharmaceutical industry to 250 billion by 2027, emphasizing organoid technology as a key direction [26] - Shenzhen has included cutting-edge fields like cell therapy and gene therapy in its support measures for the pharmaceutical and medical device sectors [26]