心血管疾病

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年轻人请注意,小心高血压“盯上”你!
Xin Hua Wang· 2025-10-07 08:53
新华社北京10月7日电(余佩璇、张帆)赶工作时手边的冰奶茶、宅家点的重辣火锅配可乐,这些年轻人习以为常的生活场景,正悄悄埋下健康 隐患——越来越多的人在体检时意外发现血压偏高,曾经被贴上"老年人专属病"标签的高血压,如今有逐步向中青年人群蔓延的趋势。中青年 高血压表现特征为何?成因有哪些?该怎样预防或干预?在第28个全国高血压日来临之际,记者采访相关专家进行解答。 "若不加以控制,高血压会造成多系统损伤,其中心脏、脑部、肾脏、眼部及血管危害更为突出。"郑博说,长期高血压会导致动脉硬化、心肌 肥厚,增加心梗、脑卒中风险;肾脏或肾动脉受损可能引发肾功能衰竭;眼底病变可能导致视力下降甚至失明。 专家表示,在中青年阶段干预并改善不良生活方式,有助于控制血压,遏制心血管疾病的发生发展。饮食上,应培养清淡饮食习惯,限制钠盐 摄入,每日食盐量不超过5克。同时,调整饮食结构,应遵循低盐、低脂、高纤维的饮食原则,多吃新鲜蔬菜、水果和全谷类食物,少吃油腻、 高盐、高糖的食物。 作息上,应保证每天7至9小时睡眠,避免周末"补觉式"作息紊乱,防止生物钟失衡。此外,还要根据自身情况选择快走、慢跑、游泳等合适的 运动方式,坚持规律锻炼, ...
长了动脉粥样硬化斑块 需要干预吗?
Yang Shi Wang· 2025-09-29 22:42
央视网消息:9月29日是世界心脏日,国家心血管病中心发布的数据显示,心血管疾病,已成为导 致我国居民死亡的首要原因。现在正是体检季,不少人在自己的体检报告上看到有动脉粥样硬化斑块, 一部分人觉得,这是正常的老化,也有人谈斑块色变,认为是心梗的信号。那么,长了斑块到底要不要 干预? ...
葛均波:警惕心脏的“午夜刺客”!年轻人还有一个“隐形杀手”
Di Yi Cai Jing· 2025-09-29 10:06
每当缺氧"警报"拉响,就会触发交感神经兴奋,导致心率飙升、血管收缩、夜间血压异常增高等症状,进而损伤血管壁,增加心脑血管疾 病风险。 近年来,我国年轻人群心血管疾病问题日益突出,心脏健康并非老年人的专属,年轻人也需提高警惕,其中压力与焦虑是心脏健康的"隐 形杀手"。 9月29日是世界心脏日,心血管疾病作为威胁人类生命健康的头号"杀手",正在侵袭越来越多的年轻人。近年来,在一些年龄相对不是很大 的心血管疾病的死亡案例中,很多发生在悄无声息的夜间。 今年世界心脏日的主题为"律动不息"。中国科学院院士、复旦大学附属中山医院心内科主任葛均波教授在近日的科普中指出,影响心血管 健康的,除了传统的"四高"(高血压、高血脂、高血糖、高体重),膳食营养、环境污染、睡眠与心理健康等因素同样不容忽视,其中阻 塞性睡眠呼吸暂停(OSA)是不容忽视的新兴危险因素。 OSA是指由于气道变窄或阻塞而导致睡眠期间的呼吸中断,全球30岁至69岁人群中预估约有9.36亿人群患有OSA。据《柳叶刀》数据,我 国约有1.76亿人群罹患OSA,居全球首位,其中,中重度OSA患者高达6552万。这一数据还在不断上升,预计到今年将超过2亿。 OSA往往 ...
云海肴回应创始人去世:他一直承受很大压力
Nan Fang Du Shi Bao· 2025-09-19 08:39
Company Overview - The founder of Yunnan Yunhaiyao Restaurant Management Co., Ltd., Zhao Han, passed away due to a sudden heart attack at the age of 40, which has garnered widespread attention [5]. - Zhao Han was instrumental in establishing the brand, opening over 100 restaurants in major cities such as Beijing, Shanghai, Guangzhou, and Shenzhen within a decade [5]. Leadership Changes - Following Zhao Han's passing, the company's board underwent adjustments, with Zhu Haiqin taking over as Chairman and CEO, assuming full responsibility for company decisions and management [3]. Industry Context - The restaurant industry has faced numerous challenges in recent years, prompting Yunhaiyao to explore various strategies, including brand collaborations and partnerships with popular media to attract new customers [3].
压力会在分子层面改变心脏功能
Ke Ji Ri Bao· 2025-09-01 00:22
Core Insights - A new study from the University of California, Davis reveals that stress affects not only the brain but also alters heart function at the molecular level [1] - The research focuses on environmental and social stressors, such as noise, crowding, and sleep disruption, and their impact on cardiovascular health, particularly how chronic psychological stress contributes to the development of cardiovascular diseases [1] Summary by Categories Research Findings - Animal experiments showed that just 10 days of acute stress can trigger inflammation, leading to subtle changes in heart function [1] - The study identified the activation of a multi-protein complex known as NLRP3 inflammasome, which acts as a key "amplifier" in the inflammatory response [1] - It is the first time scientists have confirmed that environmental stress can directly initiate this process within heart cells, releasing harmful molecules that promote heart disease [1] Implications for Health - While lifestyle changes and stress reduction are ideal for heart protection, these may be challenging for individuals living in high pollution, high noise, or high social stress environments [1] - The research team aims to identify intervenable targets based on this mechanism to pave the way for new therapies [1] - Future plans include investigating how chronic stress affects the "brain-heart axis" and its impact on gut microbiota and systemic chemical environments [1] - Collaboration with clinicians is planned to translate these findings into practical treatment options to help patients alleviate cardiac stress [1]
Cell子刊:赖仞团队揭示高脂饮食通过肠道细菌促进血栓形成的新机制
生物世界· 2025-08-01 04:07
Core Viewpoint - The study highlights the relationship between high-fat diets, gut microbiota, and cardiovascular disease (CVD), suggesting that palmitic acid levels in circulation, influenced by gut bacteria, may exacerbate thrombosis risk [2][3][12]. Group 1: Research Findings - High-fat diets increase circulating palmitic acid levels through the promotion of the gut bacterium Bacteroides thetaiotaomicron, leading to enhanced thrombosis [3][10]. - Palmitic acid has a direct pro-coagulation effect by inhibiting the endogenous anticoagulant activated protein C (APC) and enhancing platelet activation [8][10]. - The abundance of Bacteroides thetaiotaomicron is associated with elevated palmitic acid levels and a hypercoagulation state in patients with coronary artery disease [7][10]. Group 2: Dietary Implications - The composition and function of gut microbiota are directly influenced by dietary intake, particularly macronutrients like lipids, which play a crucial role in shaping host-microbe interactions [5]. - The study indicates that controlling palmitic acid and Bacteroides thetaiotaomicron could be a preventive strategy against cardiovascular diseases [12]. Group 3: Preventive Measures - Hesperidin, a dietary flavonoid, can inhibit the interaction between palmitic acid and APC, thereby preventing thrombosis induced by palmitic acid or Bacteroides thetaiotaomicron transplantation [9][10].
Nature:这种肠道细菌代谢物,促进心血管疾病,可作为治疗新靶点
生物世界· 2025-07-21 08:15
Core Viewpoint - There is a compelling link between gut microbiota and atherosclerosis, a disease characterized by cholesterol and inflammatory cell deposits in arterial walls, leading to potential health issues like stroke and heart attacks [1][5]. Group 1: Research Findings - A study published in Nature identified Imidazole Propionate (ImP), a metabolite produced by gut bacteria, as a driver of atherosclerosis, suggesting new targets for early detection and personalized treatment of cardiovascular diseases [2][10]. - The study highlights the necessity for early intervention in seemingly healthy populations due to rising morbidity and mortality rates associated with cardiovascular diseases [5]. - The research team found a strong correlation between ImP levels and the severity of atherosclerosis in both mouse models and human cohorts [7][10]. Group 2: Mechanism of Action - ImP promotes atherosclerosis through the activation of the imidazoline-1 receptor (I1R) in myeloid cells, indicating a specific signaling pathway that could be targeted for therapeutic purposes [8][10]. - Blocking the ImP-I1R signaling axis can inhibit the development of atherosclerosis induced by either ImP or a high-cholesterol diet, suggesting a potential intervention strategy [8][10]. Group 3: Implications for Treatment - The findings open new avenues for the early diagnosis and personalized treatment of atherosclerosis, emphasizing the importance of understanding gut microbiota's role in cardiovascular health [10].
最新研究证实:咖啡、茶和白开水可显著降低2型糖尿病患者死亡风险!
GLP1减重宝典· 2025-07-16 04:12
Core Viewpoint - A groundbreaking study conducted by Xi'an Jiaotong University and Harvard University provides authoritative guidance on beverage choices for diabetes patients, revealing significant differences in health impacts among various drinks [6][9]. Group 1: Research Overview - The study tracked 15,486 type 2 diabetes patients over 38 years, utilizing validated food frequency questionnaires to assess beverage intake and its correlation with all-cause mortality and cardiovascular outcomes [6][12]. - The research highlights the urgent need for dietary interventions in diabetes management, given the rising global diabetes prevalence, projected to reach 783 million by 2045 [9]. Group 2: Key Findings - High intake of sugar-sweetened beverages (SSBs) is significantly associated with increased all-cause mortality and adverse cardiovascular outcomes, while coffee, tea, plain water, and low-fat milk show protective effects [6][10]. - Specifically, the highest consumption group of SSBs had a 20% higher risk of all-cause mortality compared to the lowest intake group, while coffee drinkers had a 26% lower risk [13]. Group 3: Clinical Implications - The study suggests that reducing SSB intake and increasing consumption of healthier beverages like coffee, tea, or plain water could be a viable strategy for improving long-term outcomes and reducing mortality risk in type 2 diabetes patients [14]. - The findings provide high-quality evidence for personalized dietary guidance, emphasizing the importance of beverage choices in diabetes management [14].
中国第一大慢性肝病,正在透支年轻人
虎嗅APP· 2025-07-05 10:00
Core Viewpoint - The article discusses the rising prevalence of non-alcoholic fatty liver disease (NAFLD) in China, particularly among young adults, and highlights the associated health risks and lifestyle factors contributing to this condition [3][4][7]. Group 1: Prevalence and Demographics - NAFLD has overtaken viral hepatitis as the leading chronic liver disease in China, with the prevalence of non-alcoholic fatty liver disease reaching 21.36% by 2021 [7][10]. - A study from Wuhan University indicates that the overall prevalence of NAFLD in China approached 30% from 1999 to 2018, suggesting that nearly 3 out of 10 individuals may be affected [10]. - The disease disproportionately affects the obese population, with approximately two-thirds of obese individuals diagnosed with NAFLD [11]. - Alarmingly, about 40% of NAFLD patients globally are not obese, and in China, nearly a quarter of non-obese individuals are also affected [12][13]. - The incidence of NAFLD among young adults aged 20-24 increased by 18.34% from 2011 to 2021, the highest growth rate across all age groups [16]. Group 2: Causes and Mechanisms - The root cause of NAFLD is metabolic dysfunction rather than just dietary habits, as the liver becomes overloaded with excess fat due to metabolic disturbances [18][19]. - The latest medical guidelines have redefined NAFLD as "metabolism-related fatty liver disease," emphasizing the connection between metabolic disorders and liver health [20]. - Conditions such as obesity, high blood lipids, and diabetes significantly increase the risk of developing NAFLD, with individuals exhibiting metabolic syndrome having over four times the risk compared to the general population [20][23]. Group 3: Health Risks and Complications - NAFLD is linked to increased risks of cardiovascular diseases, with over half of NAFLD patients also facing atherosclerosis [31]. - The risk of extrahepatic malignancies, including thyroid cancer and other gastrointestinal cancers, is significantly elevated in NAFLD patients, with the incidence of non-liver cancers reaching approximately 10.58 cases per 1,000 individuals [37]. - The mortality rates from liver cirrhosis and liver cancer due to NAFLD have been rising, with cirrhosis mortality increasing from 0.36 to 0.45 per 100,000 and liver cancer mortality more than doubling from 0.35 to 0.73 per 100,000 between 1990 and 2021 [25]. Group 4: Lifestyle Interventions - Weight loss of 3% to 5% can effectively reduce liver fat accumulation, while a 5% to 7% reduction can significantly lower liver inflammation [38]. - A combination of dietary changes, such as reducing sugar and fat intake, along with regular physical activity, is essential for managing and potentially reversing NAFLD [39]. - Individuals diagnosed with NAFLD often experience a cycle of anxiety and lifestyle regression, emphasizing the need for sustained lifestyle changes to prevent further health deterioration [39].
夏日“护心”千万小心
Hang Zhou Ri Bao· 2025-07-03 03:00
Group 1 - High temperatures, high humidity, and low pressure are significant contributors to cardiovascular diseases, with an increase in heart attack patients reported in Hangzhou [1] - The director of the cardiology department at Zhejiang University Second Hospital noted that over 20 heart attack patients have been treated in the past month due to the heat [1] - Factors such as skin blood vessel dilation, increased blood viscosity, and emotional stress during hot weather can elevate the risk of heart attacks [1] Group 2 - Patients with hypertension, diabetes, and hyperlipidemia are advised to monitor their blood pressure daily and adhere strictly to medication regimens [2] - Recommendations include drinking warm water in small amounts, avoiding cold drinks, and exercising during cooler times of the day [2] - Immediate medical attention is crucial if symptoms like chest pain, shortness of breath, or dizziness occur, as these may indicate serious conditions like heart failure or stroke [2]