Core Viewpoint - The pharmaceutical sector is experiencing a decline, with significant drops in stock prices for various companies, while there is an increasing trend in domestic investment through the Hong Kong Stock Connect, indicating a mixed sentiment in the market [1]. Group 1: Stock Performance - Notable declines in pharmaceutical stocks include: - Innovent Biologics (09969) down 11.37% to HKD 14.73 - Sanofi (02257) down 11.05% to HKD 13.36 - Rongchang Biopharmaceutical (09995) down 10.4% to HKD 95.15 - Galenica (01672) down 8.57% to HKD 9.6 - Viatris (01873) down 8.14% to HKD 2.82 [1]. Group 2: Investment Trends - According to CICC, since September, the proportion of domestic investors holding pharmaceutical stocks through the Hong Kong Stock Connect has been increasing, while foreign investment has slightly decreased since mid-year [1]. - Despite the decline, the overall trend of increasing investment in innovative drugs remains unchanged [1]. Group 3: Future Outlook - The upcoming ESMO conference in mid-October is highlighted as a key event, with recommendations to focus on companies like CanSino Biologics, Kelun-Biotech, Rongchang Biopharmaceutical, and Heng Rui Medicine, which are expected to release significant data [1]. - Dongguan Securities reports that the pharmaceutical and biotechnology sector has underperformed compared to the CSI 300 index, with some previously high-performing innovative drug companies experiencing corrections [1]. - The medical research outsourcing sector is showing strength due to improved financing data and expectations of catalysts in innovative drugs, suggesting potential investment opportunities [1].

Investment Rating - The industry investment rating is maintained as "Buy" [1] Core Insights - The overall performance of the industry has shown significant improvement, with a notable recovery in revenue and profit margins [3][14] - Private medical services are under short-term pressure, while the CXO sector continues to perform well, particularly in ADC and CDMO related companies [4][6] - The core contradiction in the industry has shifted from "insufficient effective supply" to a new phase of "medical insurance cost control" due to increasing demand from an aging population [5][6] Summary by Sections Overall Industry Performance - The pharmaceutical manufacturing industry reported a cumulative revenue of 1.23 trillion yuan in the first half of 2025, a year-on-year decline of 1.20%, but the decline is narrowing month by month [5][14] - The medical service sector achieved a revenue of 883.6 billion yuan in 2025H1, with a year-on-year growth of 3.8% and a net profit growth of 43.0% [29] Private Medical Services and CXO Sector - Private medical services are experiencing short-term pressure, with the ophthalmology sector showing relatively strong performance [4][39] - The CXO sector's performance continues to improve, with significant growth in ADC and CDMO related companies [4][6] IVD and ICL Performance - The IVD sector is under pressure due to medical insurance cost control and centralized procurement policies, impacting short-term performance [5][6] - The ICL sector is facing a downward trend, with increased competition and pressure from medical insurance cost control [8][6] Investment Recommendations - The report suggests focusing on high-growth areas such as ADC CDMO and the weight-loss drug supply chain, as well as sectors with expected improvements like ophthalmology and dental services [6][29]