双载体13价肺炎球菌结合疫苗
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康泰民海协办疫苗创新论坛 探讨乙肝“防复阳”、肺炎克雷伯菌疫苗等前沿方向
Zheng Quan Shi Bao Wang· 2025-12-02 07:24
Core Insights - The forum focused on innovative vaccine development, particularly addressing the challenges and advancements in the field, with a strong emphasis on collaboration between academia and industry [1] Group 1: Vaccine Development Focus - The forum highlighted the urgent need for vaccines against "superbugs," specifically targeting Klebsiella pneumoniae, which has a mortality rate of 40%-50% and causes approximately 800,000 deaths globally each year [2] - The research team from the Army Medical University has identified effective protective components from 6,000 candidate molecules, achieving over 80% protection in pneumonia models against clinical strains of Klebsiella pneumoniae [2] - The collaboration between the Army Medical University and Kangtai Biotech aims to develop the first international vaccine for Klebsiella pneumoniae using reverse vaccinology techniques [2] Group 2: Hepatitis B Vaccine Innovations - The forum discussed the new applications of hepatitis B vaccines in chronic hepatitis B treatment, emphasizing their role in improving anti-HBs seroconversion rates and reducing HBsAg relapse rates [3] - Kangtai Biotech is developing a vaccine aimed at preventing relapse in hepatitis B patients, marking a significant shift from traditional vaccine applications focused solely on healthy populations [3] - If successful, Kangtai Biotech could become the first company in China to offer a comprehensive hepatitis B solution covering prevention, treatment, and relapse prevention [3] Group 3: Multivalent Vaccine Advancements - The forum underscored the importance of multivalent vaccines as a core development direction in preventive vaccines [4] - Kangtai Biotech has developed China's first domestic quadrivalent vaccine and the world's first dual-vector 13-valent pneumococcal conjugate vaccine, both of which have been included in the Chinese Pharmacopoeia [4] - The dual-vector 13-valent vaccine has been registered in countries like Indonesia and Nicaragua, playing a key role in Kangtai Biotech's internationalization strategy [4]
康泰生物董事、副总裁刘建凯获“第十九届药学发展奖突出成就奖”
Zheng Quan Ri Bao Zhi Sheng· 2025-12-02 06:12
Group 1 - The core achievement of Kangtai Biologics is highlighted by the award of the "Outstanding Achievement Award" to Liu Jiankai, the Vice President of the company, recognizing significant contributions to the pharmaceutical field [1] - The 19th Pharmaceutical Development Award ceremony was held in Beijing, emphasizing the importance of breakthrough innovations in the medical and health sectors [1] - A vaccine innovation forum was co-organized by Kangtai Minhai, focusing on cutting-edge vaccine research and industrialization paths, featuring discussions from prominent experts in the field [1] Group 2 - Kangtai Minhai has undertaken nine national-level research projects and received four provincial and ministerial science and technology awards since its establishment [2] - The company has launched 12 vaccine products, including the domestically first four-component vaccine and the globally first dual-carrier 13-valent pneumococcal conjugate vaccine [2] - Kangtai Minhai is currently developing vaccines for Klebsiella pneumoniae, a five-component vaccine, and a hepatitis B treatment vaccine, aiming to become a leading enterprise covering the entire hepatitis B process [2]