Group 1 - The company issued convertible bonds totaling RMB 200 million, with a net amount of RMB 198.966 million after deducting issuance costs [1][10][12] - The bonds have a maturity period of six years, from July 15, 2021, to July 14, 2027, with an annual interest rate that increases from 0.30% in the first year to 1.50% in the fifth year [1][3][12] - The initial conversion price for the bonds is set at RMB 145.63 per share, subject to adjustments based on various corporate actions [3][4][6] Group 2 - The funds raised will be allocated to two main projects: the "Baiwangxin Emergency Engineering Construction Project" and the "Adenovirus Vector COVID-19 Vaccine Workshop Project," with a total investment of RMB 317.267 million [9][10][12] - The company reported a significant decline in revenue for 2024, with total revenue of approximately RMB 2.652 billion, down 23.75% from the previous year [12] - The net profit for 2024 was RMB 20.155 million, representing a 76.60% decrease compared to the previous year, attributed to increased fixed asset depreciation and other factors [12][13] Group 3 - The company has a credit rating of AA for the bonds, with a stable outlook as assessed by Zhongjian Pengyuan Credit Rating Co., Ltd. [10][11] - The company has implemented strict management and supervision of the raised funds, ensuring compliance with relevant regulations [12][13] - The company has a total asset value of approximately RMB 14.564 billion as of December 31, 2024, reflecting a decrease of 3.46% from the previous year [12]

2025Q1疫苗行业跟踪报告（附批签发） 西南证券研究院 2025年5月 分析师：杜向阳 执业证号：S1250520030002 电话：021-68416017 邮箱：duxy@swsc.com.cn 联系人：雷瑞 邮箱：leir@swsc.com.cn 2012.08.13 10287 Hib疫苗：2025Q1批签发7批次(-50%)。 肠道病毒疫苗：2025Q1，EV71疫苗批签发4批次(-69%) 。 数据来源：医药魔方，中检院，西南证券整理，备注：本篇报告括号内均为同比变化数据，后续不一一指出，数据整理截至2025.4.7 1 2025Q1疫苗批签发批次情况 重点疫苗批签发情况： 多联苗：2025Q1，四联苗无批签发，五联苗同比下滑，赛诺菲巴斯德五联苗批签发17批次(+0%)。 肺炎疫苗：2025Q1，肺炎疫苗批累计签发23批次(-30%) ，其中13价肺炎疫苗批签发19批次(+0%)，其中 沃森生物9批次，民海生物6批次，辉瑞4批次。23价肺炎疫苗批签发4批次(-71%)。 HPV疫苗：2025Q1批签发57批次(+63%)。其中双价HPV疫苗批签发42批次（+367%），双价苗需求快速 增长，全部 ...

2024年及2025年一季度，疫苗行业均呈现比较严重的下滑趋势。从财务数据看，行业总营收从2020年的 1060亿元增至2023年的1637亿元，年均复合增长率达11.5%，2021年同比增速更达34.5%。然而2024 年，行业总营收骤降至1283亿元，同比下滑21.6%，为近五年首次负增长，显示行业进入调整期。 从利润表现看，行业净利润在2021年达到309亿元峰值后持续下滑，2024年降至120亿元，较峰值缩水 61%，同时盈利质量出现恶化迹象，净利润率从2021年的21.7%降至2024年的9.4%，成本压力显著抬 升。主要原因在于疫苗渠道库存压力较大，导致企业发货受到不利影响以及2价HPV疫苗、PCV13、 Vero细胞狂苗等竞争格局趋于激烈。 个股方面，头部企业业绩分化现象显著。其中，天坛生物、西藏药业逆势突围，天坛生物2024年营收60 亿元，同比增长17.6%；净利润15亿元，同比增长36.4%，毛利率提升至54%。西藏药业2024年净利润10 亿元，同比增长25%，毛利率连续三年超94%。 而智飞生物、万泰生物受HPV疫苗市场竞争加剧及集采影响业绩均出现大幅下滑。智飞生物2023年营收 52 ...

投资评级：买入（维持） 农林牧渔/动物保健Ⅱ 科前生物（688526.SH） 经营韧性十足，创新驱动成长 2025 年 04 月 30 日 《经营短期承压，静待 2024H2 业绩修 复—公司信息更新报告》-2024.9.1 陈雪丽（分析师） 王高展（联系人） chenxueli@kysec.cn 证书编号：S0790520030001 wanggaozhan@kysec.cn 证书编号：S0790123060055 日期 2025/4/30 当前股价(元) 16.25 一年最高最低(元) 19.56/11.00 总市值(亿元) 75.75 流通市值(亿元) 75.75 总股本(亿股) 4.66 流通股本(亿股) 4.66 近 3 个月换手率(%) 46.1 股价走势图 -40% -20% 0% 20% 40% 2024-04 2024-08 2024-12 2025-04 科前生物 沪深300 数据来源：聚源 相关研究报告 《后周期业绩有望修复向上，新品持 续发力持续成长—公司信息更新报 告》-2024.11.3 经营韧性十足，创新驱动成长，维持"买入"评级 公司发布 2024 年年报及 2025 年一季报 ...

Core Viewpoint - The impact of the U.S. tariff policy on Chinese pharmaceutical companies is relatively limited, with many companies reporting normal operations and minimal effects from the tariffs [1][2][3][4][5]. Company Responses - Heng Rui Pharmaceutical stated that overseas sales account for only 2.56% of its revenue, indicating that U.S. tariffs will have a minimal impact on its business [1]. - Han Yu Pharmaceutical emphasized its diversified market layout, which mitigates risks from single market policy changes, and reported no significant impact from the tariffs [2]. - WuXi AppTec acknowledged that tariffs would have some effect but deemed it manageable, highlighting their optimized supply chain and global presence [3]. - Kang Tai Biological reported no exports to the U.S. and is focusing on markets along the Belt and Road, indicating a strategic shift to other regions [4]. - Mindray Medical confirmed that while some raw materials are imported from the U.S., they are taking measures to ensure supply safety and view the tariff impact as a one-time issue [4]. Industry Trends - The Chinese vaccine industry is rapidly developing, with companies like CanSino Biologics transitioning from followers to leaders in vaccine technology, focusing on domestic innovation [6][7]. - The overall sentiment among companies is that the tariff policy presents an opportunity for domestic product substitution, with many firms prepared to adapt to changing market conditions [5][8]. - Companies are increasingly focusing on technological innovation and expanding into emerging markets to counteract potential supply chain disruptions caused by tariffs [5][6][7].

2024年，国内疫苗行业业绩承压明显，头部二类疫苗上市公司康泰生物（300601）(300601.SZ)的业绩 也坐上了"过山车"：第一、第二季度营收和净利均呈现同比双降，第三季度虽实现营收同比双位数增 长，但第四季度业绩再度急转直下。全年实现营收和归母净利润为26.52亿元和2.02亿元，分别同比下滑 23.75%和76.59%。而在今年一季度，虽然公司止住了营收下滑的颓势，然而归母净利润仍同比腰斩 58.51%至2243.41万元。 作为反映疫苗企业市场竞争力的关键指标，批签发量常被视作产品销量的先行信号。然而，证券之星关 注到，康泰生物2024年的批签发量与营收增长呈现背离：尽管其多款核心疫苗产品的批签发量均实现不 同程度的增长，但公司整体营收不增反降，这一数据表明，其批签发量未能有效转化为实际销量的增 长。此外，公司在财务端的隐忧凸显，截至今年一季度末，康泰生物应收账款高达28.54亿元，同比增 长5.1%，应收账款周转率和存货周转率均仅为0.23，反映出公司收款风险增加的同时，资金运营效率低 下。2024年至今，公司股价跌幅超48%。 或受益于乙肝疫苗批签发量增长的带动，2024年康泰生物来自免疫规 ...