Investment Rating - The report indicates a positive investment outlook for the allergic asthma drug industry in China, with a projected compound annual growth rate (CAGR) of 15.6% from 2024 to 2030, leading to a market size of 467 billion yuan by 2030 [5][9][11]. Core Insights - The current treatment landscape for allergic asthma includes a variety of therapies such as inhaled corticosteroids (ICS), allergen immunotherapy (AIT), and biologics targeting type 2 inflammation, suitable for moderate to severe cases [5][6]. - The market for allergic asthma drugs in China is expanding, driven by an increasing patient population exceeding 40 million and a growing demand for innovative treatments that focus on long-term control rather than just symptom relief [9][11]. - The report highlights the rapid development of biologics, with several monoclonal antibodies targeting IL-5, IL-4Rα, and TSLP showing promise in clinical trials, thus diversifying treatment options for severe asthma patients [12][22]. Summary by Sections Treatment Patterns - The treatment modalities for allergic asthma primarily consist of chemical drugs, allergen immunotherapy, and biologics. Biologics are particularly effective for patients with specific biomarkers [5][6]. Market Size and Growth - The Chinese allergic asthma drug market grew from 11.2 billion yuan in 2018 to an estimated 19.6 billion yuan in 2024, with a CAGR of 9.8%. It is expected to reach 46.7 billion yuan by 2030, reflecting a significant increase in demand due to a rising patient base and improved treatment awareness [9][11]. Drug Development - The report notes a diverse pipeline for new drug development in the allergic asthma sector, with multiple candidates in various clinical trial phases targeting different pathways, including IL-5 and TSLP [12][22]. Biologics Overview - Four classes of monoclonal antibodies have been approved for asthma treatment: anti-IgE, anti-IL-5, anti-IL-5R, and anti-TSLP. These biologics are recommended as add-on therapies for patients who remain uncontrolled on standard treatments [12][22]. Future Trends - The report anticipates a "demand upgrade-technology breakthrough-policy empowerment" phase for the allergic asthma drug market in China, aiming to create a comprehensive ecosystem for innovative treatments that cater to all patient demographics [11][12].

Core Points - The article highlights the increasing prevalence of "thunderstorm asthma" during the autumn season, particularly in northern regions, due to frequent thunderstorms and rising allergen levels in the air [1][2] - It emphasizes the need for heightened awareness among individuals with pre-existing respiratory conditions, such as asthma and allergic rhinitis, as they are at higher risk during these weather events [1] Group 1 - Thunderstorm conditions can lead to the fragmentation of allergens like pollen and mold into smaller particles, increasing their inhalation risk [1] - The high-risk groups for "thunderstorm asthma" include individuals with asthma, hay fever, and those with weakened immune systems, such as children and the elderly [1] - Symptoms of "thunderstorm asthma" are similar to regular asthma but are more dangerous and can persist for 3 to 5 years in some patients [1] Group 2 - Medical professionals recommend preventive measures for susceptible individuals, including the use of antihistamines and carrying emergency asthma medications during thunderstorms [2] - Personal protective actions include keeping windows closed, avoiding outdoor activities, and wearing N95 masks and goggles if going outside [2] - After exposure, individuals should change clothes and wash their nasal passages and face to reduce the risk of allergen exposure [2]

Core Viewpoint - The article highlights the increasing risk of thunderstorm asthma due to frequent thunderstorm weather, emphasizing the need for public awareness and preventive measures against this serious health threat [1][2]. Group 1: Thunderstorm Asthma Overview - Thunderstorm asthma occurs when strong winds during thunderstorms disperse allergens like pollen and mold into the air, breaking them into smaller particles that can be easily inhaled [1]. - Symptoms of thunderstorm asthma are similar to regular asthma but can be more severe and potentially life-threatening, with symptoms lasting longer and possibly recurring for years after the initial event [1]. Group 2: Prevention Measures - Individuals with allergies should monitor weather forecasts, especially pollen counts, and limit outdoor activities before and after thunderstorms [2]. - Using air purifiers and keeping windows closed can help reduce indoor allergen concentrations during thunderstorms [2]. - Regular cleaning of homes to prevent mold growth and dust accumulation is essential for minimizing indoor allergens [2]. Group 3: Emergency Response - In case of an asthma attack, it is crucial to use emergency medications like budesonide/formoterol or albuterol immediately, with a recommendation to inhale every 20 minutes if symptoms persist [2][3]. - Maintaining an upright position and staying hydrated can help keep airways open during an asthma attack [3]. - If symptoms worsen, seeking medical attention is vital, and patients should continue using emergency medications while en route to the hospital [3].

Core Viewpoint - The article highlights the increasing risk of thunderstorm asthma due to frequent thunderstorm weather, emphasizing the need for public awareness and preventive measures [1][2]. Group 1: Thunderstorm Asthma Risks - Thunderstorm weather can lead to a significant increase in airborne allergens, such as pollen and mold, which can trigger severe asthma attacks [1]. - The particles generated during thunderstorms are typically 2 to 3 micrometers in diameter, making them easily inhalable and capable of causing acute allergic reactions [1]. Group 2: Prevention Measures - Individuals with a history of allergies should monitor weather forecasts, especially pollen counts, and limit outdoor activities during thunderstorms [2]. - Using air purifiers and keeping windows closed can help reduce indoor allergen concentrations during thunderstorm events [2]. - Regular cleaning of living spaces to prevent mold growth and dust accumulation is recommended to minimize indoor allergens [2]. Group 3: Emergency Response - In case of an asthma attack, it is crucial to use emergency medications like budesonide/formoterol or albuterol immediately, with a recommendation to inhale every 20 minutes if symptoms persist [2][3]. - Maintaining an upright position and staying hydrated can help ease breathing difficulties during an asthma attack [3]. - If symptoms worsen or do not improve, seeking immediate medical attention is essential, where further treatments may include intravenous corticosteroids or mechanical ventilation [3].