9月29日，由北京市委网信办主办、新京报贝壳财经承办的"京彩不设限·经济热力站"月度主题走访活动 在北京举办，本期主题为"创新策源 健康领航"。 活动亮点纷呈，数十位主流媒体记者与网络大V一同走访调研了中关村生命科学园展厅、新生巢创新中 心、北京万泰生物（603392）药业股份有限公司、华辉安健（北京）生物科技有限公司、北京诺诚健华 医药科技有限公司等企业，深入拆解"明星"创新药从靶点发现到临床获批的完整路径。 这些企业不仅见证了北京在医药健康领域前沿技术赛道的重点布局，也记录下一座城如何以临床需求为 牵引、以政策赋能为支撑，撬动资本、人才、平台、数据等全要素，加速医药创新从"书架"走向"货 架"，为首都经济高质量发展注入源源不断的健康动能。 据中关村生命科学园展厅工作人员张祎介绍，经过多年发展，中关村生命科学园已成为中国生命科学领 域创新资源最密集的区域之一。园区聚集了北京生命科学研究所、国家蛋白质科学中心等一批国家级研 发机构，已建设10余个国家和省部级重点研发中心，入驻创新型医药企业1000多家。园区及周边布局了 北大国际医院、北大第六医院、高博医院等医疗机构，总床位数3000余张。其中，高博医院是全国 ...

Core Viewpoint - WanTai Bio's 2025 semi-annual report reveals significant declines in revenue and profit, marking the first half-year loss since its listing in 2020, primarily due to market adjustments and government procurement impacts on its vaccine segment [2][6]. Financial Performance - In the first half of 2025, WanTai Bio achieved revenue of approximately 844 million yuan, a year-on-year decline of 38.25% [2]. - The net profit attributable to shareholders was approximately -144 million yuan, a decrease of 155.30% year-on-year [2]. - The net profit attributable to shareholders after deducting non-recurring gains and losses was approximately -243 million yuan, down 481.93% year-on-year [2]. - Basic earnings per share were -0.11 yuan, a decline of 152.38% year-on-year [2]. Vaccine Segment Overview - WanTai Bio's vaccine business has a diversified pipeline centered around HPV vaccines, including the world's only hepatitis E vaccine and a two-valent HPV vaccine that has received WHO-PQ certification [3]. - The nine-valent HPV vaccine has been approved for market release, becoming the first domestically produced and the second globally approved nine-valent HPV vaccine [3]. - The company is advancing multiple new vaccine pipelines, including a 20-valent pneumonia conjugate vaccine and a recombinant zoster vaccine, among others [3][4]. R&D Progress - The nine-valent HPV vaccine has been approved for market release, with male Phase III clinical trials initiated [4]. - The 20-valent pneumonia conjugate vaccine is progressing through Phase I clinical trials, with all groups expected to complete enrollment by February 2024 [4]. - The recombinant zoster vaccine is in the IND registration application phase, while the freeze-dried varicella live attenuated vaccine has completed Phase III clinical studies [4]. Competitive Landscape - The vaccine industry in China is experiencing intensified competition, with increasing product homogeneity and price competition becoming the norm [6]. - Domestic companies are actively expanding into overseas markets, while multinational corporations are increasing investments in China, leading to heightened competition on a global scale [6]. - WanTai Bio is focusing on optimizing its response mechanisms across R&D, production, marketing, and internationalization to address these competitive risks [6].

Core Viewpoint - WanTai Bio's 2025 semi-annual report reveals significant declines in revenue and profit, marking the first half-year loss since its listing in 2020, primarily due to market adjustments and government procurement impacts on its vaccine segment [1][2][3]. Financial Performance - In the first half of 2025, WanTai Bio achieved revenue of approximately 844 million yuan, a year-on-year decline of 38.25% [1]. - The net profit attributable to shareholders was approximately -144 million yuan, a decrease of 155.30% year-on-year [1]. - The net profit after deducting non-recurring gains and losses was approximately -243 million yuan, down 481.93% year-on-year [1]. - Basic earnings per share were -0.11 yuan, a decline of 152.38% year-on-year [1]. Business Overview - WanTai Bio, established in 1991, operates primarily in two sectors: in vitro diagnostics and vaccines [4]. - The company has developed a diversified pipeline centered around HPV vaccines, including the world's only hepatitis E vaccine and a two-valent HPV vaccine that has received WHO-PQ certification [4]. - The nine-valent HPV vaccine has been approved for market release, becoming the first domestically produced and the second globally approved nine-valent HPV vaccine [4]. Research and Development Progress - The R&D expenses decreased by 42.39% year-on-year, mainly due to reduced costs associated with the transition of the nine-valent HPV vaccine [3]. - Various vaccines are in different stages of development, including: - Nine-valent HPV vaccine: Approved for market release and male Phase III clinical trials initiated [5]. - 20-valent pneumonia conjugate vaccine: Phase I clinical trials progressing as planned [5]. - Recombinant shingles vaccine: IND registration application in progress [5]. - Other vaccines, including live attenuated varicella vaccines and universal nasal spray influenza vaccines, are also advancing as scheduled [5]. Industry Competition - The vaccine industry in China is experiencing intensified competition, with increasing product homogeneity and price competition becoming the norm [6]. - Domestic companies are expanding into overseas markets, while multinational corporations are increasing investments in China, leading to heightened competition on a global scale [6]. - WanTai Bio is actively optimizing its response mechanisms across R&D, production, marketing, and internationalization to address these competitive risks [7].