Core Viewpoint - The article emphasizes the economic feasibility of converting non-grain biomass waste, such as straw, into high-value products through comprehensive innovation across the entire supply chain [2][4]. Group 1: Research and Development - Professor Jin Mingjie’s team at Nanjing University of Science and Technology has addressed key challenges in the biorefining process of lignocellulosic biomass, including high raw material collection and transportation costs, stringent pretreatment conditions, toxic byproducts, low bioconversion efficiency, and difficulties in lignin degradation [2]. - A novel pretreatment technology and biorefining system have been developed to solve critical issues in the biorefining process [2]. - The team has developed a high-solid enzymatic hydrolysis technology that achieves a fermentable sugar concentration exceeding 200 g/L, allowing for efficient fermentation of hydrolysate into products like cellulose ethanol, lactic acid, succinic acid, citric acid, and lipids without the need for washing or detoxification [2]. Group 2: Lignin Utilization - The research includes the analysis of lignin biodegradation pathways and the discovery of new lignin-degrading enzymes, employing a "biological funnel" strategy to construct multiple engineered strains for the efficient conversion of lignin into high-value products such as muconic acid and gallic acid [2]. Group 3: Company Formation and Impact - In 2024, Professor Jin Mingjie founded Suzhou Limi Biotechnology Co., Ltd. in Suzhou High-tech Zone, which has developed globally leading complete technologies with independent intellectual property rights, breaking through the industrialization bottleneck of converting non-grain biomass waste into high-value biochemical products [4]. - The establishment of this company is considered epoch-making in the field of biomass utilization [4]. Group 4: Industry Engagement - Professor Jin Mingjie is scheduled to present a report titled "Biorefining of Lignocellulosic Biomass Based on 'Sugar' Platform" at the 2025 Non-Grain Biomass High-Value Utilization Forum (NFUCon 2025) in Hangzhou, Zhejiang, from January 27 to 29, 2025, inviting industry participation for exchange [5].

Core Viewpoint - The article establishes an analytical method using high-performance liquid chromatography (HPLC) to determine six phenolic substances in Conghua olives, optimizing various conditions for effective separation and detection [2][4][40]. Methodology - The method involves weighing 0.5g of dried Conghua olive powder, dissolving it in isopropyl alcohol, and subjecting it to ultrasonic extraction for 30 minutes, followed by solid-phase extraction and filtration before HPLC analysis [4][6]. - The Eclipse XDB-C18 chromatographic column was selected for separation, and a diode array detector was used to optimize the testing conditions [4][12]. Results - The study found that the peak areas of gallic acid, hydroxytyrosol, oleuropein, and elenolic acid showed good linear relationships within specified concentration ranges, with R² values greater than 0.995 [4][5]. - Detection limits for the six substances were established, with gallic acid at 2.09 mg/kg and hydroxytyrosol at 2.20 mg/kg, among others [5][33]. Recovery and Precision - The recovery rates for the substances ranged from 84% to 116%, with relative standard deviations between 0.014% and 0.15%, indicating the method's reliability [5][34]. Conclusion - The optimized method provides a reliable approach for determining the content of six phenolic substances in Conghua olives, contributing valuable insights for researchers in the field [40].

Core Viewpoint - The company, Qicheng Biotechnology, has faced significant challenges leading to the termination of its IPO review, primarily due to declining financial performance and concerns regarding its construction projects and compliance issues [1][4][16]. Group 1: Market Position - Qicheng Biotechnology is a leading player in the hydrolyzed tannin industry, holding a global market share of approximately 7.12% in the tannic acid market and 9.07% in the gallic acid market as of 2023, indicating strong competitive positioning [2][3][24]. - The global market size for tannic acid and gallic acid in 2023 was approximately 1.16 billion and 1.91 billion respectively, highlighting the industry's growth potential [2]. Group 2: Financial Performance - The company's revenue has shown a downward trend, with reported figures of 359.76 million, 291.13 million, and 312.38 million for the years 2021 to 2023, respectively, and a projected decline in 2024 [4][17]. - The net profit attributable to shareholders decreased from 52.91 million in 2021 to 39.40 million in 2022, and slightly increased to 40.37 million in 2023, but is expected to drop to 29.85 million in 2024 [4][17]. - The company anticipates a further decline in revenue and net profit for the first quarter of 2025, with expected decreases of 2.94%-10.84% in revenue and 40.33%-48.86% in net profit [5][17]. Group 3: Construction Projects and Compliance Issues - Significant investments in construction projects, such as the Qicheng Biotechnology Industrial Park, have not yet been capitalized, raising concerns about the authenticity and reasonableness of these expenditures [9][10]. - The company has faced scrutiny for not completing necessary construction permits and for starting projects without proper approvals, although local authorities have indicated that these issues are not severe enough to warrant penalties [11][12][14][15]. - The company has been subject to multiple administrative penalties from various regulatory bodies, indicating ongoing compliance challenges [11][12]. Group 4: Market Dynamics and Competitive Landscape - The company has experienced fluctuations in revenue from its industrial tannic acid product, primarily due to changes in customer procurement strategies and market competition [21]. - The demand for mixed feed additives containing tannic acid has declined significantly, with utilization rates dropping to 7.17% and 9.17% in 2023 and 2024, respectively, largely due to the financial struggles of key customers [22]. - The competitive landscape is characterized by price reductions in response to increased market pressure, which has affected the company's profit margins [24].