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南京医科大学最新Nature子刊:汪秀星/张茜/钱旭/张军霞等揭示阻断肿瘤微环境乳酸转运,可增强胶质母细胞瘤的抗肿瘤免疫
生物世界· 2026-01-07 04:09
撰文丨王聪 编辑丨王多鱼 排版丨水成文 胶质母细胞瘤 (GBM) 是成年人中最常见、最具侵袭性的恶性脑肿瘤。胶质母细胞瘤 表现出显著的异质 性, 患者在确诊后通常只能存活 12-18 个月。 尽管经过了几十年的研究,但该疾病尚无治愈方法,而且 已批准的治疗方法 (例如手术、放疗和化疗) 在延长预期寿命方面效果有限。 胶质母细胞瘤的 肿瘤微环境 (TME) 复杂,以 胶质母细胞瘤干细胞 (GSC) 为主,并有 肿瘤相关巨噬 细胞 (TAM) 浸润,且存在异常的代谢途径。 乳酸 ( Lactate ) 是一种关键的糖酵解代谢物,可促进 肿瘤进展;然而,胶质母细胞瘤的肿瘤微环境中 乳酸转运 和 乳酸化修饰 的作用机制仍不清楚。 2026 年 1 月 6 日,南京医科大学基础医学院 汪秀星 教授、北卡罗来纳大学教堂山分校 Jeremy N. Rich 教授、南京医科大学基础医学院 张茜 副教授、南京医科大学公共卫生学院 钱旭 教授、南京医科大学第一 附属医院 张军霞 教授作为共同通讯作者 ( 李大奇 、 崔高源 、 Kailin Yang 、 陆晨飞 、 江雨韩 、 张乐 为论文共同第一作者) ,在 Nature 子 ...
金丹科技:坚持双轮驱动战略,已实施股份回购并推进员工持股计划
Sou Hu Cai Jing· 2026-01-06 03:57
来源:市场资讯 针对上述提问,金丹科技回应称:"尊敬的投资者您好,公司坚持'乳酸+可降解材料'双轮驱动战略,以 市场需求为导向,聚焦核心主业推进技术创新与市场拓展,目前经营一切正常,不存在应披露而未披露 的重大事项。公司治理始终严格遵循上市公司规范要求,积极与机构投资者保持沟通,努力提升治理透 明度与市场认可度;分别已于2024年和2025年实施了股份回购,同时积极推进股员工持股计划,充分体 现了管理层对公司长期发展的信心。二级市场股价受宏观环境、行业周期、市场情绪等多重因素综合影 响,波动具有复杂性,敬请投资者注意风险。感谢您的关注。" 声明:市场有风险,投资需谨慎。本文为AI基于第三方数据生成,仅供参考,不构成个人投资建议。 有投资者在互动平台向金丹科技提问:"董秘你好,请问公司如何看待今年股价涨幅与大盘的差异?是 否有提振措施。" ...
金丹科技(300829.SZ):出口到日本的产品主要是乳酸,乳酸钠和乳酸钙等
Ge Long Hui· 2025-12-17 01:15
格隆汇12月17日丨金丹科技(300829.SZ)在投资者互动平台表示,公司出口到日本的产品主要是乳酸, 乳酸钠和乳酸钙等,截止到当前2025年出口到日本的营业额约占总营收的0.4%,最终数据以公司2025 年年度审计数据为准。 ...
联泓新科,1.5亿元加码聚乳酸
DT新材料· 2025-12-08 16:05
Core Viewpoint - The company Lianhong Xinke plans to increase its investment in its subsidiary Jiangxi Academy of Biological New Materials Co., Ltd. by 150 million yuan to enhance its strategic development in biodegradable materials [2][3]. Group 1: Investment and Capital Structure - The investment will consist of 88.5 million yuan added to registered capital and 61.5 million yuan to capital reserves, aimed at improving the subsidiary's working capital and asset-liability structure [2]. - Following the capital increase, Lianhong Xinke's ownership in Jiangxi Academy will rise from 51% to 65.7%, increasing the subsidiary's registered capital from 207 million yuan to 295 million yuan [3][4]. Group 2: Business Focus and Financial Performance - Jiangxi Academy focuses on the research, production, and sales of lactic acid and polylactic acid, which are key components in the biodegradable materials sector [2]. - For the fiscal year 2024, Jiangxi Academy reported revenues of 4.836 million yuan and a net loss of 2.2296 million yuan. In the first three quarters of 2025, revenues increased to 52.8966 million yuan with a net profit of 15.7672 million yuan [5].
联泓新科拟向科院生物增资1.5亿元
Zhi Tong Cai Jing· 2025-12-05 13:55
联泓新科(003022)(003022.SZ)发布公告,生物可降解材料是公司战略发展的重点方向之一,公司控 股子公司江西科院生物新材料有限公司(下称"科院生物"或"标的公司")主要从事乳酸、聚乳酸的研发、 生产与销售。为加快公司战略布局及发展,补充科院生物流动资金,改善其资产负债结构,公司拟以自 有资金向科院生物增资1.5亿元,科院生物其他股东不同步参与本次增资。 ...
联泓新科(003022.SZ)拟向科院生物增资1.5亿元
智通财经网· 2025-12-05 13:51
智通财经APP讯,联泓新科(003022.SZ)发布公告,生物可降解材料是公司战略发展的重点方向之一,公 司控股子公司江西科院生物新材料有限公司(下称"科院生物"或"标的公司")主要从事乳酸、聚乳酸的研 发、生产与销售。为加快公司战略布局及发展,补充科院生物流动资金,改善其资产负债结构,公司拟 以自有资金向科院生物增资1.5亿元,科院生物其他股东不同步参与本次增资。 ...
联泓新科(003022.SZ):拟向科院生物增资1.5亿元
Ge Long Hui A P P· 2025-12-05 11:41
格隆汇12月5日丨联泓新科(003022.SZ)公布,生物可降解材料是联泓新材料科技股份有限公司战略发展 的重点方向之一,公司控股子公司江西科院生物新材料有限公司(下称"科院生物"或"标的公司")主要 从事乳酸、聚乳酸的研发、生产与销售。为加快公司战略布局及发展,补充科院生物流动资金,改善其 资产负债结构,公司拟以自有资金向科院生物增资1.5亿元,科院生物其他股东不同步参与本次增资。 ...
联泓新科:拟对子公司江西科院生物新材料有限公司增资
Mei Ri Jing Ji Xin Wen· 2025-12-05 11:40
每经AI快讯,联泓新科(SZ 003022,收盘价:19.17元)12月5日晚间发布公告称,生物可降解材料是 联泓新材料科技股份有限公司战略发展的重点方向之一,公司控股子公司江西科院生物新材料有限公司 主要从事乳酸、聚乳酸的研发、生产与销售。为加快公司战略布局及发展,补充科院生物流动资金,改 善其资产负债结构,公司拟以自有资金向科院生物增资1.5亿元,科院生物其他股东不同步参与本次增 资。 2025年1至6月份,联泓新科的营业收入构成为:先进高分子材料占比56.7%,特种精细材料占比 23.35%,副产品及其他占比19.95%。 每经头条(nbdtoutiao)——秒光、售罄!银行大额存单成稀缺资源,2%以上产品很难抢,有的门槛高 达1000万元!专家:存款利率或长期下行 (记者 王晓波) 截至发稿,联泓新科市值为256亿元。 ...
促进可持续发展 金丹科技发布员工持股计划
Zheng Quan Ri Bao· 2025-11-24 13:39
Core Points - The employee stock ownership plan (ESOP) of Jindan Technology is designed to enhance the incentive mechanism and attract talent, aiming for sustainable growth [1][2] - The performance assessment for the ESOP includes company-level and individual-level evaluations for the fiscal years 2026 and 2027 [1] - The company targets a revenue growth of no less than 10% or a net profit growth of no less than 20% in 2026, and a revenue growth of no less than 30% or a net profit growth of no less than 30% in 2027 [1] - The ESOP will involve a maximum of 147 key personnel, including directors, senior management, and core technical staff, with a total share transfer not exceeding 1 million shares at a price of 11.12 yuan per share [2] Company Overview - Jindan Technology is a national high-tech enterprise that produces lactic acid using modern microbial fermentation technology, with corn as its core raw material [1]
金丹科技跌2.00%,成交额8187.03万元,主力资金净流出862.82万元
Xin Lang Cai Jing· 2025-11-18 06:57
Core Viewpoint - JinDan Technology's stock price has experienced fluctuations, with a recent decline of 2.00% and a year-to-date decrease of 0.75%, indicating potential volatility in the market [1]. Financial Performance - For the period from January to September 2025, JinDan Technology achieved a revenue of 1.204 billion yuan, representing a year-on-year growth of 8.41% [2]. - The net profit attributable to shareholders for the same period was 132 million yuan, reflecting a significant year-on-year increase of 30.06% [2]. - Cumulatively, the company has distributed 84.0133 million yuan in dividends since its A-share listing, with 47.8824 million yuan distributed over the past three years [2]. Stock Market Activity - As of November 18, JinDan Technology's stock was trading at 18.60 yuan per share, with a market capitalization of 4.227 billion yuan [1]. - The stock has seen a trading volume of 81.8703 million yuan and a turnover rate of 2.75% on the same day [1]. - The net outflow of main funds was 8.6282 million yuan, with significant selling pressure observed in large orders [1]. Company Overview - JinDan Technology, established on August 10, 2006, and listed on April 22, 2020, specializes in the research, production, and sales of lactic acid and its derivatives [1]. - The company's main revenue sources include lactic acid (61.94%), lactic acid salts (20.67%), by-products (9.40%), and other products (7.99%) [1]. - The company operates within the basic chemical industry, specifically in food and feed additives [1].