Core Viewpoint - The documentary "拾光" produced by Huaxi Biological and "Great National Brands" showcases the journey of Huaxi Biological from breaking through the technical barriers of hyaluronic acid to creating a complete synthetic biology ecosystem, reflecting the evolution of China's biotechnology industry from following to leading [1][21]. Group 1: Historical Context and Technological Breakthroughs - In 1934, American scientists first isolated hyaluronic acid from bovine vitreous body, and by the 1970s, Western countries had industrialized it through extraction from chicken combs, but faced limitations in extraction efficiency and high costs, restricting its application to high-value fields like medicine and cosmetics [3]. - In 2000, Huaxi Biological initiated independent research and development of hyaluronic acid, successfully achieving large-scale production through microbial fermentation, breaking foreign technical barriers and significantly reducing costs, making hyaluronic acid more accessible [5]. Group 2: Research and Development Achievements - As of June 30, 2025, Huaxi Biological has applied for 1,081 patents, including 855 invention patents, establishing a comprehensive R&D capability from gene editing to large-scale fermentation [5]. - The company has undergone systematic upgrades of hyaluronic acid technology, achieving significant milestones such as large-scale production via microbial fermentation, the global first "enzyme-cutting method" for producing oligo-hyaluronic acid, and the establishment of a synthetic biology platform [8][10]. Group 3: Market Applications and Brand Development - Huaxi Biological has expanded the applications of hyaluronic acid from the medical field to food, skincare, reproductive health, and textiles, broadening the industry's prospects [10]. - The company has built a global R&D network with top institutions like Tsinghua University and Harvard University, and invested over 3 billion yuan in a leading synthetic biology pilot transformation platform [10]. Group 4: Innovation Ecosystem and Commercial Success - Huaxi Biological's complete innovation system, from basic research to large-scale production, allows it to bridge the gap in technology commercialization, exemplified by the success of its product "润百颜" which has sold hundreds of millions of units globally [11]. - The company has developed a range of brands covering health, beauty, and quality of life, demonstrating the tangible impact of technology on consumers' lives [15]. Group 5: Cultural and Social Contributions - Huaxi Biological actively contributes to cultural and sports vitality in Chinese cities through investments in landmark projects and cultural commercial ecosystems [17]. - The "Cloud Public Welfare" project has reached 19 provinces and 43 ethnic minority areas, supporting intangible cultural heritage projects and donating medical equipment to rural schools [19].

Core Viewpoint - Runbaiyan, a core strategic brand under Huaxi Biological, has consistently adhered to "cell repair" skincare technology, showcasing a commitment to technological innovation and strategic determination throughout its evolution [2][3]. Group 1: Brand Evolution and Innovation - Runbaiyan became the first domestic brand of cross-linked hyaluronic acid dermal fillers in 2012, pioneered the secondary essence category in 2014, and entered the skincare market in 2018 with the launch of the national trend IP Forbidden City lipstick [2]. - In 2025, Runbaiyan will launch a "personalized customization" project, marking a significant advancement in integrating online and offline services [3][6]. Group 2: Personalized Skincare Development - The personalized skincare concept has historical roots, dating back to 1853 with Guerlain's "Imperial Water" for Empress Eugénie, but has traditionally been limited to luxury markets [6][7]. - The evolution of personalized skincare in China has progressed through three stages: - 1.0 Stage: Basic skincare products with minimal differentiation [8]. - 2.0 Stage: Focus on specific consumer pain points and skin types [8]. - 3.0 Stage: Aiming for customized solutions that address individual skin conditions, though facing challenges in cost and scalability [8][9]. Group 3: Technological Foundation - Runbaiyan's approach to personalized skincare is rooted in advanced technologies in cell biology, sugar biology, and regenerative medicine, allowing for a deeper understanding of skin issues at the cellular level [9][11]. - The brand utilizes its proprietary INFHA cell repair technology to create a favorable environment for skin cells, emphasizing the importance of foundational skin health [11][22]. Group 4: Customization Process - The customization process begins with AI-driven skin diagnostics, utilizing extensive data from various sources to ensure accurate assessments and tailored skincare solutions [14][16]. - Runbaiyan has developed a modular formula design that can address 15,625 different skincare needs through 108 customized solutions, reflecting a rigorous development process [20][22]. Group 5: Production and Delivery - The brand has achieved flexible production capabilities, allowing for small batch production starting from 500 grams, and can switch formulas in as little as 12 minutes, ensuring efficiency and precision in meeting consumer demands [23][25]. - The first personalized customization experience was launched in Qingdao, where consumers can receive tailored skincare products directly from the store [26][28]. Group 6: Market Impact and Vision - Runbaiyan aims to democratize personalized skincare, making advanced solutions accessible to a broader audience, thus addressing unmet skincare needs and enhancing overall skin health [30][32].

真正优秀的成分，总会随着时间焕发新的生命力。 在护肤领域，透明质酸（ HA），也就是我们熟知的玻尿酸，堪称初代 "顶流巨星"。从保湿到抗皱，从修复到紧致，它的功效几乎覆盖了消费者对护肤 品的所有期待。然而，随着胜肽、烟酰胺等新兴成分的涌现，一时间，质疑声四起：曾经风靡护肤界的玻尿酸，如今是否还能保持它的优势？ 这种断层式领先表明，无论市场如何变化，透明质酸依然是品牌配方中的核心选择。 为什么透明质酸能够保持这样的地位？答案很简单 ——它不仅是一种经典成分，更是一种经过时间验证、安全可靠且功效显著的护肤原料。 透明质酸 的抗皱紧致 地位坚如磐石 数据不会撒谎。 根据中国香妆和用户说联合发布的《 2025原料成分趋势洞察榜单》，透明质酸稳坐"抗皱紧致"成分应用热度榜首。在2025年1-2月备 案的护肤品中，含有透明质酸的产品数量高达10562个，是第二名烟酰胺（5504个）的近两倍。 早期的透明质酸提取工艺复杂且成本高昂。 1949 年，Boas 从鸡冠中分离出透明质酸。提取 1g 透明质酸需要 200 公斤鸡冠（约 2 万只鸡），导致生 产成本极高，每公斤售价高达10万美元，被誉为"液体黄金"。 从 "液体黄金 ...