Core Viewpoint - The company, Eddie Pharmaceuticals, is making significant advancements in the development of HIV treatments, particularly focusing on the new generation of integrase inhibitors and long-acting preventive medications, while also expanding its human protein business. Group 1: HIV Treatment Development - The company has completed a Phase I/IIa clinical study for its new integrase inhibitor, CC017, showing a significant viral load reduction of 2.34 Log10 copies/mL after 10 days of monotherapy, with over 90% of participants achieving complete viral suppression after 18 days of combination therapy [2] - The company reported a 58.49% year-on-year increase in sales revenue for its HIV new drugs, reaching 129 million yuan in the first half of 2025, indicating successful commercialization efforts [3] - The company is actively participating in academic conferences to promote its products and enhance its brand image, while also focusing on patient education and team optimization to improve treatment quality and service processes [3] Group 2: Long-Acting Preventive Medications - The company is accelerating the development of long-acting HIV medications, responding to national strategies for HIV prevention, with two new long-acting drug patents filed and accepted [4] - The market for long-acting medications is expected to grow due to their lower side effects and better privacy, positioning the company to capture a significant share of the pre-exposure prophylaxis (PrEP) market [4] Group 3: Human Protein Business Expansion - The company has established strong relationships with upstream suppliers and is integrating operations following the acquisition of Nanda Pharmaceutical, which has positively impacted its revenue and profitability [6] - The human protein market is growing, with significant advancements in collaboration with Nanda Pharmaceutical, including the approval of new drug applications for innovative human protein products [7] Group 4: Financial Performance - The company's mid-2025 report shows a 100.19% increase in main revenue to 362 million yuan and a 120.23% increase in net profit to 9.19 million yuan [8] - The second quarter of 2025 saw a revenue increase of 86.71% year-on-year, indicating strong financial performance despite some negative net profit figures [8]

Investment Rating - The report assigns a "Buy" rating for the company, indicating a positive outlook for investment [3][7]. Core Insights - The domestic HIV drug market is experiencing rapid growth, driven primarily by oral combination tablets. The market size for HIV drugs in China is projected to exceed 11 billion yuan by 2027, with a compound annual growth rate of 27% from 2017 to 2023 [6][50]. - The company has a multi-targeted approach in its HIV treatment drug pipeline, addressing diverse patient needs. Key products include the oral non-nucleoside reverse transcriptase inhibitors, which have been approved and included in the national medical insurance directory, leading to significant sales growth [6][7]. - The company is also focusing on developing long-acting pre-exposure prophylaxis (PrEP) drugs, which have substantial market potential in the U.S. market, estimated to be in the tens of billions of dollars [6][7]. Financial Data and Profit Forecast - The company is expected to achieve total revenue of 806 million yuan in 2025, with a year-on-year growth rate of 92.8%. By 2027, revenue is projected to reach 1.263 billion yuan [2]. - The net profit attributable to the parent company is forecasted to be 7 million yuan in 2025, with significant growth anticipated in subsequent years, reaching 166 million yuan by 2027 [2]. - The gross profit margin is expected to improve from 63.2% in 2025 to 75.2% by 2027, reflecting enhanced operational efficiency [2]. Company Overview - The company, established in 2009, specializes in the research, development, production, and sales of pharmaceutical products, focusing on HIV and human protein fields. It has established a strong competitive position in the domestic HIV market [14][23]. - The acquisition of Nanda Pharmaceutical in 2024 is part of the company's strategy to integrate human protein raw materials and formulations, enhancing its product offerings and market reach [28][32]. Market Dynamics - The report highlights the shift in the HIV drug market from government procurement to a combination of government-funded treatments, medical insurance, and out-of-pocket expenses, indicating a more diversified market structure [50][52]. - The company’s HIV drugs are expected to become mainstream products in the domestic market due to their superior efficacy and convenience compared to older government-procured drugs [6][9].

Investment Rating - The investment rating for the company is "Buy" (maintained) [5] Core Views - The company achieved a turnaround in Q1 2025, with revenue of 198 million yuan, representing a year-on-year increase of 113% and a quarter-on-quarter increase of 66.37%. The net profit attributable to shareholders was 16 million yuan, up 214.52% year-on-year and 119.41% quarter-on-quarter [5] - The company's HIV new drug sales reached 62 million yuan in Q1 2025, showing positive commercial progress. The new drug's revenue for 2024 was 150 million yuan, reflecting a year-on-year growth of 103.73% [6] - The company is expanding its pipeline with various innovative drugs and has made significant progress in clinical trials, including the ACC017 tablet and AD108 injection [7] Financial Summary - In 2024, the company reported revenue of 418 million yuan (up 1.57% year-on-year) and a net loss of 141 million yuan (down 85.63% year-on-year). The projected revenues for 2025, 2026, and 2027 are 737 million yuan, 1,037 million yuan, and 1,237 million yuan respectively, with expected net profits of -3 million yuan, 21 million yuan, and 77 million yuan [8] - The gross margin for Q1 2025 was 62.04%, an increase of 20 percentage points year-on-year, while the net margin was 12.94%, up 27.59 percentage points year-on-year [5] - The company's earnings per share (EPS) for 2025 is projected to be -0.01 yuan, with subsequent years showing improvements to 0.05 yuan in 2026 and 0.18 yuan in 2027 [8]

Investment Rating - The investment rating for the company is "Buy" (maintained) [1] Core Views - The company is experiencing steady revenue growth in 2024, with a reported revenue of 419 million yuan, reflecting a year-on-year increase of 1.92%. However, the net profit attributable to the parent company is -129 million yuan, a significant decline of 70.79% year-on-year [4][7] - The company is focusing on the commercialization of its HIV drug, which is showing strong momentum, supported by clinical research evidence [5] - The acquisition of Nanda Pharmaceutical is part of the company's strategy to deepen its presence in the human protein business and create a second growth curve [6] Financial Summary - In 2024, the company's total assets increased by 9.35% to 1.91 billion yuan, while the equity attributable to the parent company decreased by 11.94% to 999 million yuan [4] - The company's revenue projections for 2024-2026 have been adjusted to -129 million yuan, -3 million yuan, and 21 million yuan respectively, with corresponding EPS of -0.31, -0.01, and 0.05 yuan per share [4] - The company's gross margin is expected to improve from 55.4% in 2024 to 70.2% in 2026, indicating a positive trend in profitability [7]