Core Viewpoint - The recent IPO of Saint Bella, known as the "Hermès" of confinement centers, saw a significant first-day increase of 33.74%, reaching a market capitalization of HKD 53.66 billion. However, industry experts view this listing as a desperate move due to the company's ongoing financial struggles, with a total loss of HKD 773 million and no net profit despite rising revenues [1][3]. Company Overview - Saint Bella's listing is part of a broader trend, with over 30 fertility-related companies currently seeking IPOs, including Babycare and Weituo Biotech, as they aim to capitalize on the market before potential downturns [2][3]. - The company has positioned itself at the intersection of maternity care and technology to support its valuation during the IPO process [1]. Financial Performance - Saint Bella reported a revenue increase of 42.6% to HKD 560 million, but still faced a net loss of HKD 420 million, marking a 103.43% increase in losses [9][10]. - Other companies in the sector, such as Newman Health and Haipai Ke, are also experiencing significant financial challenges, with losses and declining profits despite high revenues [7][10]. Market Dynamics - The fertility market in China is under pressure due to a declining birth rate, with 2024 projected to see only 9.54 million newborns, a significant drop from 14.65 million in 2019 [7][11]. - The low market penetration rate of 9.2% in assisted reproduction compared to around 30% in developed countries indicates substantial room for growth, but also highlights the challenges faced by domestic companies [11][12]. Challenges Faced by Companies - High operational costs and aggressive market expansion strategies have led to financial strain for many fertility companies, resulting in a cycle of increasing revenue without corresponding profit growth [16][17]. - Companies like Haipai Ke have reported significant losses, with cumulative losses reaching HKD 1.854 billion, despite high transaction volumes [7][10]. Future Outlook - The assisted reproduction market is expected to grow significantly, with projections indicating a market size of HKD 108.9 billion by 2029, driven by a compound annual growth rate of 12.9% from 2024 to 2029 [18]. - Companies are encouraged to target lower-income markets and innovate to reduce costs, while also considering international expansion to tap into global opportunities [18][20].

Core Viewpoint - Jingze Biopharma has submitted an application for listing on the Hong Kong Stock Exchange, focusing on assisted reproductive and ophthalmic drugs, with eight candidate drugs in its pipeline [1][3]. Group 1: Company Overview - Jingze Biopharma aims to commercialize its first product, JZB30, a recombinant human follicle-stimulating hormone (FSH) lyophilized powder injection, expected to generate revenue by 2026 [1][3]. - The company has previously attempted to list on the Shanghai Stock Exchange's Sci-Tech Innovation Board but faced delays in completing the necessary guidance [1][3]. Group 2: Product Pipeline and Market Competition - All of Jingze Biopharma's late-stage products are generic drugs, with JZB30 competing against established products like Follitropin [4][6]. - The domestic market for recombinant human FSH is dominated by companies like Merck and Jinsai Pharmaceutical, which have significant market shares [6][9]. - The market for injectable recombinant human FSH has shown limited growth, with sales fluctuating between 1.12 billion and 2.02 billion from 2015 to 2023 [6][9]. Group 3: Financial Situation - Jingze Biopharma has been operating at a loss, with projected losses of approximately 246 million and 243 million for 2023 and 2024, respectively [9][10]. - The company has raised about 930 million through six rounds of financing, with a significant portion raised during the C+ round [9][10]. - As of the end of 2024, the company's cash reserves were critically low, with only 68.6 million and 27.08 million remaining [10].